Download or read book Histamine and H1 Antihistamines in Allergic Disease Second Edition written by F. Estelle R. Simons and published by CRC Press. This book was released on 2002-06-26 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the strengths of the best-selling first edition, Histamine and H1-Antihistamines in Allergic Disease, Second Edition presents the latest advances and current research in histamine, histamine receptors, and H1-antihistamines for practical application in allergy, immunology, dermatology, otolaryngology, and pulmonology. Contains over 2000 contemporary references-300 more than the first edition! This Second Edition offers new chapters detailing cost-effective techniques to treat and manage allergic rhinoconjunctivitis, urticaria, angioedema, atopic dermatitis, asthma, and anaphylaxis the use of nonsedating antihistamines in care of the elderly the safety of specific antihistamines during pregnancy and lactation quality-of-life comparisons among different H1-antihistamines used in the treatment of allergic rhinitis and provides completely revised and expanded material describing the role of histamine in the pathogenesis of asthma regimens for the prevention of anaphylaxis and anaphylactoid reactions the potential of combined antihistamine and antileukotriene therapy With contributions from more than 20 esteemed international authorities, the Second Edition of Histamine and H1-Antihistamines in Allergic Disease is an in-depth guide suitable for allergists, immunologists, pulmonologists, respiratory specialists, dermatologists, otolaryngologists, pharmacologists, and graduate students in these disciplines.
Download or read book Histamine and H1 Antihistamines in Allergic Disease Second Edition written by F. Estelle R. Simons and published by CRC Press. This book was released on 2002-06-26 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the strengths of the best-selling first edition, Histamine and H1-Antihistamines in Allergic Disease, Second Edition presents the latest advances and current research in histamine, histamine receptors, and H1-antihistamines for practical application in allergy, immunology, dermatology, otolaryngology, and pulmonology. Contains over 2000 contemporary references-300 more than the first edition! This Second Edition offers new chapters detailing cost-effective techniques to treat and manage allergic rhinoconjunctivitis, urticaria, angioedema, atopic dermatitis, asthma, and anaphylaxis the use of nonsedating antihistamines in care of the elderly the safety of specific antihistamines during pregnancy and lactation quality-of-life comparisons among different H1-antihistamines used in the treatment of allergic rhinitis and provides completely revised and expanded material describing the role of histamine in the pathogenesis of asthma regimens for the prevention of anaphylaxis and anaphylactoid reactions the potential of combined antihistamine and antileukotriene therapy With contributions from more than 20 esteemed international authorities, the Second Edition of Histamine and H1-Antihistamines in Allergic Disease is an in-depth guide suitable for allergists, immunologists, pulmonologists, respiratory specialists, dermatologists, otolaryngologists, pharmacologists, and graduate students in these disciplines.
Download or read book Histamine and H1 antihistamines in Allergic Disease written by F. E. R. Simons and published by . This book was released on 2002 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Histamine and H1 receptor Antagonists in Allergic Disease written by F. E. R. Simons and published by . This book was released on 1996 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides comprehensive, up-to-date information on histamine receptors and H1-receptor antagonists, reviewing fundamental science and presenting advances in therapy. It discusses novel H1-receptor antagonists, including loratadine, cetrizine and acrivastine, and examines the role of topical H1-antagonists such as levocabastine and azelastine. The clinical scientific basis of antagonistic use is explored.
Download or read book Histamine Intolerance written by Reinhart Jarisch and published by Springer. This book was released on 2014-11-10 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histamine is an important mediator of allergic diseases, but knowledge of histamine as a cause of numerous non-allergic symptoms and signs is limited. This book offers wide-ranging coverage of histamine intolerance. There is extensive background discussion of the origin of histamine, its content in food and alcoholic beverages and intolerance to red wine. Diagnosis of histamine intolerance is explained and the various symptoms of histamine intolerance are clearly described. Subsequent chapters cover the relation of histamine to a wide variety of conditions, including drug intolerance, atopic dermatitis, seasickness and osteoporosis. This book will prove of value in clinical practice by facilitating differential diagnosis, which is by no means straightforward given the multiplicity of symptoms of histamine intolerance and by assisting in the selection of therapeutic measures.
Download or read book Histamine and Histamine Receptors in Health and Disease written by Yuichi Hattori and published by Springer. This book was released on 2017-05-22 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview on the field. This chapter will also link the book to the previous HEP volume on histamine receptors and the recent HEP volume on the pharmacology of itch. Great attention will be paid to complementation of existing literature while avoiding undue duplication. The book will cover new methods for analysis of histamine and histamine metabolites, development of methods for histamine receptor analysis, signal transduction, histamine release, regulation of immune cells by histamine, histamine metabolism and associated diseases, regulation of major organ systems by histamine and development of new drugs and experimental tools for the study of histamine receptors.
Download or read book The Essence of Analgesia and Analgesics written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2010-10-14 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.
Download or read book Itch written by E. Carstens and published by CRC Press. This book was released on 2014-02-25 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Download or read book Management of Allergy in the 1990 s written by Michael A. Kaliner and published by Hogrefe & Huber Publishing. This book was released on 1989 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for anyone involved with the study or treatment of allergies, this text presents a variety of insights regarding current and future tactics, as well as strategies important to practitioners in this area. It is especially directed at paediatricians, internists and GPs.
Download or read book History of Allergy written by K.-C. Bergmann and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-27 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.
Download or read book Histamine in Inflammation written by Robin Thurmond and published by Springer Science & Business Media. This book was released on 2011-06-29 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: The year 2010 marks the centennial for the identification of histamine and the first glimpse of its many physiological functions. From these initial findings a rich tapestry of research has uncovered roles for histamine in almost every physiological process with new findings emerging every year. These diverse roles of histamine have made for fertile ground for the discovery of novel therapeutics, and these drugs have been so successful that the term “antihistamine” has entered the common lexicon. This volume is an attempt to give a snapshot in time as to the current understanding of the role of histamine in just one important therapeutic area—inflammation. The first three chapters provide some background context for the rest of the book starting out with a historical perspective by Figueroa and Shankley. Bongers et al provide an overview of the pharmacology of the four histamine receptors and the chapter by Hiroshi Ohtsu describes how histamine is synthesized as well as the insights derived from mice where this synthesis is disrupted. The next several chapters discuss disease areas where histamine is known to be involved. Chapter 4 by Thomas Taylor-Clark outlines the role of histamine in allergic rhinitis, an area were antihistamines are commonly used. This is also true for ocular allergy as discussed by Ohbayashi et al. Both of these chapters highlight aspects of these conditions that are still not well-controlled and suggest the utility of new antihistamines targeting other histamine receptors.
Download or read book Biomedical Aspects of Histamine written by Nancy Khardori and published by Springer Science & Business Media. This book was released on 2010-09-30 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its identification by Sir Henry H. Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacological effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic neurotransmission and numerous brain functions, secretion of pituitary hormones, regulation of gastrointestinal and circulatory functions, cardiovascular system, as well as inflammatory reactions, modulation of the immune response, endocrine function and homeostasis, and other important areas. This book is a compendium of the current state of established and investigational literature on Histamine, its receptors and their Agonists and antagonists. It provides a comprehensive overview of histamine biology in the field of biochemistry, cell biology, molecular biology, immunology, allergy, neurobiology, pharmacology, microbiology and reproductive biology. The first section on Histamine biology and physiology leads into subsequent sections on enzymology, pharmacology, regulation of the immune system and cell proliferation and role in allergic and other diseases including acid peptic diseases, inflammatory diseases, autoimmune and cancer diseases, nervous system, reproductive functions and hematopoiesis. The compilation of chapters in the book presents the most recent advances in histamine research and bridges the basic and clinical aspects of histamine biology.
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Download or read book Histamine in the brain written by Jian-Sheng Lin and published by Frontiers Media SA. This book was released on 2015-03-18 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.
Download or read book Management of Allergic and Nonallergic Rhinitis written by and published by . This book was released on 2002 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacology of Itch written by Alan Cowan and published by Springer. This book was released on 2015-04-10 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its complexity and its negative effects on the quality of life of the distressed patients. Like pain, not all itches are the same. Unlike pain, there are no standard drugs equivalent to aspirin and morphine. Epidemiological studies emphasize the high incidence and economic costs of itch (pruritus). It is the most prevalent symptom of a wide variety of allergic and inflammatory skin conditions (e.g., psoriasis, atopic dermatitis), is associated with several systemic diseases (e.g., chronic kidney and liver disease), and occurs in patients undergoing hemodialysis, spinal administration of opioids, and in those suffering from AIDS. The reader will learn about the multiple pathways for itch and their interactions with pain. The relationship between these closely related, yet distinct sensory phenomena, will be emphasized. Both itch and pain use several common molecules to send signals to the brain. Thus, drugs that have been, and are being, developed as analgesics may also attenuate intractable itch. This has been an exciting and very necessary turn of events since traditional H-1 receptor antagonists are ineffective in blocking the pruritus associated with kidney failure and cholestasis. The clinical chapters will provide insights into contemporary treatment regimens for pruritus in different human scenarios.
Download or read book Therapeutic Index of Antihistamines written by Jean-Pierre Rihoux and published by Lewiston, N.Y. ; Toronto : Hogrefe & Huber. This book was released on 1992 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the therapeutic indices of antihistaminic drugs in relation to their unwanted effects and their possible additional beneficial effects from both the non-clinical and clinical viewpoints. While the relationships between antihistaminic activity and central nervous sedation are becoming resolved, clinicians must be aware of other clinical indicators of potential hazard with higher doses of a drug. The debate on additional beneficial properties of antihistamines will rage for many years yet, but this book presents a clear picture of what is known.
