Download or read book Heterogeneous Transmission at the Drosophila Larval Neuromuscular Junction Revealed by Single bouton Optical Imaging written by Giovanna Guerrero and published by . This book was released on 2004 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2005 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuromuscular Junctions in Drosophila written by and published by Academic Press. This book was released on 1999-04-29 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach.This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories.Key Features* Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system* Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function* Written in clear language that is easily understandable to readers not already familiar with fruit fly research* Includes numerous diagrams and extensive reference lists
Download or read book Optogenetics written by Hiromu Yawo and published by Springer Nature. This book was released on 2021-01-05 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
Download or read book Brain Plasticity and Behavior written by Bryan Kolb and published by Psychology Press. This book was released on 1995 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.
Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Download or read book The Embryonic Development of Drosophila melanogaster written by Jose A. Campos-Ortega and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: " . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.
Download or read book Drosophila Models for Human Diseases written by Masamitsu Yamaguchi and published by Springer. This book was released on 2018-06-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
Download or read book Chemical Ecology of Insects written by William J. Bell and published by Springer. This book was released on 2013-11-27 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our objective in compiling a series of chapters on the chemical ecology of insects has been to delineate the major concepts of this discipline. The fine line between presenting a few topics in great detail or many topics in veneer has been carefully drawn, such that the book contains sufficient diversity to cover the field and a few topics in some depth. After the reader has penetrated the crust of what has been learned about chemical ecology of insects, the deficiencies in our understanding of this field should become evident. These deficiencies, to which no chapter topic is immune, indicate the youthful state of chemical ecology and the need for further investigations, especially those with potential for integrating elements that are presently isolated from each other. At the outset of this volume it becomes evident that, although we are beginning to decipher how receptor cells work, virtually nothing is known of how sensory information is coded to become relevant to the insect and to control the behavior of the insect. This problem is exacerbated by the state of our knowledge of how chemicals are distributed in nature, especially in complex habitats. And finally, we have been unable to understand the significance of orientation pathways of insects, in part because of the two previous problems: orientation seems to depend on patterns of distri bution of chemicals, the coding of these patterns by the central nervous system, and the generation of motor output based on the resulting motor commands.
Download or read book Ultradian Rhythms from Molecules to Mind written by David Lloyd and published by Springer Science & Business Media. This book was released on 2008-08-27 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: 5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism’s behavior to its environment has depended on one of life’s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al. , 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit regular periodicities since they constitute a mechanism of timing. Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.
Download or read book Peroxisome Biology Experimental Models Peroxisomal Disorders and Neurological Diseases written by Gérard Lizard and published by Springer. This book was released on 2021-01-09 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the biology and biochemistry of peroxisomes, and discusses the contribution of these organelles to peroxisomal and neurodegenerative diseases. It begins with a detailed introduction to the biogenesis and metabolic functions of peroxisomes, and highlights their role in oxidative stress and in lipid metabolism such as fatty acid oxidation. The following chapters focus on the molecular and clinical aspects of peroxisomal disorders caused by defects in peroxisomal function. In particular, the biological aspects of peroxisomal biogenesis disorders such as Zellweger syndrome and Heimler syndrome are discussed. This includes their underlying genetic causes as well as the biochemical and metabolic defects associated with the disorders. In addition, several chapters cover recent observations suggesting an association between peroxisomal dysfunction and neurodegenerative diseases such as Alzheimer's, Multiple Sclerosis and other degenerative cerebellar pathologies. The final section of the book discusses important cell and animal models for studying the role of peroxisomes in human diseases and presents current therapeutic strategies for their treatment. This book deals with a highly topical subject that is at the heart of current research, and represents a valuable contribution for all students and researchers who want to understand the complex biology of peroxisomes and their role in human diseases.
Download or read book The Sticky Synapse written by Michael Hortsch and published by Springer Science & Business Media. This book was released on 2009-06-07 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.
Download or read book Biorational Control of Arthropod Pests written by Isaac Ishaaya and published by Springer Science & Business Media. This book was released on 2009-08-28 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: For nearly 50 years, pest control was mostly based on broad-spectrum conv- tional insecticides such as organochlorines, organophosphates, carbamates and pyrethroids. However, the severe adverse effects of pesticides on the environment, problems of resistance reaching crisis proportions and public protests led to stricter regulations and legislation aimed at reducing their use. Ways to reduce the use of synthetic pesticides in plant protection and to use more alternative and novel me- ods for pest control or biorational control are the challenges of pest control for the twenty-first century. The term biorational (biological + rational) pesticides can be defined as the use of specific and selective chemicals, often with a unique modes of action, that are compatible with natural enemies and the environment, with minimal effect on n- target organisms. Biorational control is based on a diversity of chemical, biological and physical approaches for controlling insect pests which results in minimum risk to man and the environment.
Download or read book Developmental Timing written by and published by Academic Press. This book was released on 2013-09-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Current Topics in Developmental Biology covers developmental timing, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as the timing of developmental programs in Drosophila, temporal patterning of neural progenitors, and environmental modulation of developmental timing.
Download or read book Document Image Analysis written by Lawrence O'Gorman and published by Institute of Electrical & Electronics Engineers(IEEE). This book was released on 1995 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Confocal Microscopy written by Stephen W. Paddock and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Confocal Microscopy Methods and Protocols, Stephen Paddock and a highly skilled panel of experts lead the researcher using confocal techniques from the bench top, through the imaging process, to the journal page. They concisely describe all the key stages of confocal imaging-from tissue sampling methods, through the staining process, to the manipulation, presentation, and publication of the realized image. Written in a user-friendly, nontechnical style, the methods specifically cover most of the commonly used model organisms: worms, sea urchins, flies, plants, yeast, frogs, and zebrafish. Centered in the many biological applications of the confocal microscope, the book makes possible the successful imaging of both fixed and living specimens using primarily the laser scanning confocal microscope. The powerful hands-on methods collected in Confocal Microscopy Methods and Protocols will help even the novice to produce first-class cover-quality confocal images.
