Download or read book The Structure of Biological Science written by Alexander Rosenberg and published by Cambridge University Press. This book was released on 1985-01-25 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preface p. ix Chapter 1 Biology and Its Philosophy p. 2 1.1 The Rise of Logical Positivism p. 2 1.2 The Consequences for Philosophy p. 4 1.3 Problems of Falsifiability p. 6 1.4 Philosophy of Science Without Positivism p. 8 1.5 Speculation and Science p. 10 Introduction to the Literature p. 11 Chapter 2 Autonomy and Provincialism p. 13 2.1 Philosophical Agendas versus Biological Agendas p. 13 2.2 Motives for Provincialism and Autonomy p. 18 2.3 Biological Philosophies p. 21 2.4 Tertium Datur? p. 25 2.5 The Issues in Dispute p. 30 2.6 Steps in the Argument p. 34 Introduction to the Literature p. 35 Chapter 3 Teleology and the Roots of Autonomy p. 37 3.1 Functional Explanations in Molecular Biology p. 39 3.2 The Search for Functions p. 43 3.3 Functional Laws p. 47 3.4 Directively Organized Systems p. 52 3.5 The Autonomy of Teleological Laws p. 59 3.6 The Metaphysics and Epistemology of Functional Explanation p. 62 3.7 Functional Explanation Will Always Be with Us p. 65 Introduction to the Literature p. 67 Chapter 4 Reductionism and the Temptation of Provincialism p. 69 4.1 Motives for Reductionism p. 69 4.2 A Triumph of Reductionism p. 73 4.3 Reductionism and Recombinant DNA p. 84 4.4 Antireductionism and Molecular Genetics p. 88 4.5 Mendel's Genes and Benzer's Cistrons p. 93 4.6 Reduction Obstructed p. 97 4.7 Qualifying Reductionism p. 106 4.8 The Supervenience of Mendelian Genetics p. 11 4.9 Levels of Organization p. 117 Introduction to the Literature p. 119 Chapter 5 The Structure of Evolutionary Theory p. 121 5.1 Is There an Evolutionary Theory? p. 122 5.2 The Charge of Tautology p. 126 5.3 Population Genetics and Evolution p. 130 5.4 Williams's Axiomatization of Evolutionary Theory p. 136 5.5 Adequacy of the Axiomatization p. 144 Introduction to the Literature p. 152 Chapter 6 Fitness p. 154 6.1 Fitness Is Measured by Its Effects p. 154 6.2 Fitness As a Statistical Propensity p. 160 6.3 The Supervenience of Fitness p. 164 6.4 The Evidence for Evolution p. 169 6.5 The Scientific Context of Evolutionary Theory p. 174 Introduction to the Literature p. 179 Chapter 7 Species p. 180 7.1 Operationalism and Theory in Taxonomy p. 182 7.2 Essentialism--For and Against p. 187 7.3 The Biological Species Notion p. 191 7.4 Evolutionary and Ecological Species p. 197 7.5 Species Are Not Natural Kinds p. 201 7.6 Species As Individuals p. 204 7.7 The Theoretical Hierarchy of Biology p. 212 7.8 The Statistical Character of Evolutionary Theory p. 216 7.9 Universal Theories and Case Studies p. 219 Introduction to the Literature p. 225 Chapter 8 New Problems of Functionalism p. 226 8.1 Functionalism in Molecular Biology p. 228 8.2 The Panglossian Paradigm p. 235 8.3 Aptations, Exaptations, and Adaptations p. 243 8.4 Information and Action Among the Macromolecules p. 246 8.5 Metaphors and Molecules p. 255 Bibliography p. 266 Index p. 273.

Download or read book The Journal of Biological Chemistry written by and published by . This book was released on 1924 with total page 1822 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. 3-140 include the society's Proceedings, 1907-41

Download or read book Classification Disease and Evidence written by Philippe Huneman and published by Springer. This book was released on 2014-10-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This anthology of essays presents a sample of studies from recent philosophy of medicine addressing issues which attempt to answer very general (interdependent) questions: (a) what is a disease and what is health? (b) How do we (causally) explain diseases? (c) And how do we distinguish diseases, i.e. define classes of diseases and recognize that an instance X of disease belongs to a given class B? (d) How do we assess and choose cure/ therapy? The book is divided into three sections: classification, disease and evidence. In general, attention is focused on statistics in medicine and epidemiology, issues in psychiatry and connecting medicine with evolutionary biology and genetics. Many authors position the theories that they address within their historical contexts. The nature of health and disease will be addressed in several essays that also touch upon very general questions about the definition of medicine and its status. Several chapters scrutinize classification because of its centrality within philosophical problems raised by medicine and its core position in the philosophical questioning of psychiatry. Specificities of medical explanation have recently come under a new light, particularly because of the rise of statistical methods and several chapters investigate these methods in specific contexts such as epidemiology or meta-analysis of random testing. Taken together this collection addresses the question of how we gather, use and assess evidence for various medical theories. The rich assortment of disciplines featured also includes epidemiology, parasitology and public health, while technical aspects such as the application of game theory to medical research and the misuse of the DSM in forensic psychiatry are also given an airing. The book addresses more than the construction of medical knowledge, however, adding cogent appraisal of the processes of decision making in medicine and the protocols used to justify therapeutic choices.

Download or read book Research at the Intersection of the Physical and Life Sciences written by National Research Council and published by National Academies Press. This book was released on 2010-03-25 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, the natural sciences have been divided into two branches: the biological sciences and the physical sciences. Today, an increasing number of scientists are addressing problems lying at the intersection of the two. These problems are most often biological in nature, but examining them through the lens of the physical sciences can yield exciting results and opportunities. For example, one area producing effective cross-discipline research opportunities centers on the dynamics of systems. Equilibrium, multistability, and stochastic behavior-concepts familiar to physicists and chemists-are now being used to tackle issues associated with living systems such as adaptation, feedback, and emergent behavior. Research at the Intersection of the Physical and Life Sciences discusses how some of the most important scientific and societal challenges can be addressed, at least in part, by collaborative research that lies at the intersection of traditional disciplines, including biology, chemistry, and physics. This book describes how some of the mysteries of the biological world are being addressed using tools and techniques developed in the physical sciences, and identifies five areas of potentially transformative research. Work in these areas would have significant impact in both research and society at large by expanding our understanding of the physical world and by revealing new opportunities for advancing public health, technology, and stewardship of the environment. This book recommends several ways to accelerate such cross-discipline research. Many of these recommendations are directed toward those administering the faculties and resources of our great research institutions-and the stewards of our research funders, making this book an excellent resource for academic and research institutions, scientists, universities, and federal and private funding agencies.

Download or read book Femtochemistry VII written by Michele Kimble and published by Elsevier. This book was released on 2006-10-03 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Femtochemistry VII presents the most recent developments in femtochemistry and highlights the significance of the field today. This book contains extracts from the proceedings, presentations and posters from the Femtochemistry VII conference, held in Washington D.C., on July 17-22, 2005. The stimulating conference was opened by Professor Ahmed Zewail (1999 Nobel Prize Winner), and as was evident by the attendees at the conference, had a very active program with the presentation of numerous talks and a large number of posters. This collection of papers reflects the remarkable progress that has been made in femtosecond spectroscopy, and especially to its emergence as a field of research devoted to chemistry and biology, giving rise to femtochemistry and femtobiology. Subjects covered include imaging, structural dynamics, and spectroscopies, fundamentals of reaction dynamics, salvation phenomenta, liquids and interfaces, aggregates/particles/surfaces, protein dynamics and photobiology, quantum control, and intense laser-matter interactions. Subjects covered by this book include imaging, structural dynamics, and spectroscopies; fundamentals of reaction dynamics; salvation phenomenta; liquids and interfaces; aggregates/particles/surfaces; protein dynamics and photobiology; quantum control; and intense laser-matter interactions. This book would appeal to chemists, physicists and biologists in the fields of atomic and molecular science. * Contains the most recent developments in Femtochemistry from the Femtochemistry VII conference* Highlights the significance of femtochemistry today* Displays extracts from the proceedings, presentations and posters from the conference

Download or read book Personalised Health Management Systems written by C. Nugent and published by IOS Press. This book was released on 2005-11-29 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development and advancement of personalised health management systems requires the consideration of advances in sensor technologies and advanced textiles in addition to nano technologies and evolving information and communication technologies. We are now living in an environment where changes in healthcare structures and requests from patients to have an increased participation in their own healthcare are demanding the availability of affordable and readily available personalised health management systems. Recent research has taken us a step closer in providing such solutions, however, efforts are still required to address the issues of integration of new technologies into existing health care practices, implications of interoperability of services, analysis of results following large scale clinical evaluations and development of technology which is small, reliable and affordable by its users. This publication shows a synergy between research efforts in three diverse areas; sensor technologies, advanced textiles and nanotechnology and computing. It brings together researchers from academia, industry and clinical healthcare provision and emphasises the need for multi-disciplinary collaborations in the future developments of personalised health management systems.

Download or read book Surface Organometallic Chemistry Molecular Approaches to Surface Catalysis written by Jean-Marie Basset and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface organometallic chemistry is a new field bringing together researchers from organometallic, inorganic, and surface chemistry and catalysis. Topics ranging from reaction mechanisms to catalyst preparation are considered from a molecular basis, according to which the "active site" on a catalyst surface has a supra-molecular character. This. the first book on the subject, is the outcome of a NATO Workshop held in Le Rouret. France, in May. 1986. It is our hope that the following chapters and the concluding summary of recommendations for research may help to provide a definition of surface organometallic chemistry. Besides catalysis. the central theme of the Workshop, four main topics are considered: 1) Reactions of organometallics with surfaces of metal oxides, metals. and zeolites; 2) Molecular models of surfaces, metal oxides, and metals; 3) Molecular approaches to the mechanisms of surface reactions; 4) Synthesis and modification of zeolites and related microporous solids. Most surface organometallic chemistry has been carried out on amorphous high-surf ace-area metal oxides such as silica. alumina. magnesia, and titania. The first chapter. contributed by KNOZINGER. gives a short summary of the structure and reactivity of metal oxide surfaces. Most of our understanding of these surfaces is based on acid base and redox chemistry; this chemistry has developed from X-ray and spectroscopic data, and much has been inferred from the structures and reactivities of adsorbed organic probe molecules. There are major opportunities for extending this understanding by use of well-defined (single crystal) oxide surfaces and organometallic probe molecules.

Download or read book Femtochemistry and Femtobiology written by Abderrazzak Douhal and published by World Scientific. This book was released on 2002 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains important contributions from top international scientists on the-state-of-the-art of femtochemistry and femtobiology at the beginning of the new millennium. It consists of reviews and papers on ultrafast dynamics in molecular science.The coverage of topics highlights several important features of molecular science from the viewpoint of structure (space domain) and dynamics (time domain). First of all, the book presents the latest developments, such as experimental techniques for understanding ultrafast processes in gas, condensed and complex systems, including biological molecules, surfaces and nanostructures. At the same time it stresses the different ways to control the rates and pathways of reactive events in chemistry and biology. Particular emphasis is given to biological processes as an area where femtodynamics is becoming very useful for resolving the structural dynamics from techniques such as electron diffraction, and X-ray and IR spectroscopy. Finally, the latest developments in quantum control (in both theory and experiment) and the experimental pulse-shaping techniques are described.

Download or read book Waterborne Pathogens written by Helen Bridle and published by Academic Press. This book was released on 2020-10-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Waterborne Pathogens: Detection Methods and Applications, Second Edition, gives an overview of advanced and emerging technologies in the detection of a range of waterborne pathogens. In addition, the book presents existing methodologies, highlights where improvements can be made, includes applications, and touches on the ways in which new technologies can be applied in water management. Finally, the book addresses issues of sample preparation (from sampling, to concentration and enrichment), a key stage in any detection protocol. - Gives an overview of advanced emerging technologies in the detection of a range of waterborne pathogens - Ensures the latest research developments, along with other changes in the sector, e.g., regulations and approaches are current - Provides an overview of the existing approaches and key challenges before discussing sample processing and detection - Presents existing methodologies and highlights where improvements can be made

Download or read book The Living Soil written by Jean-Michel Gobat and published by Science Publishers. This book was released on 2004 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study looks at the fundamentals of soil science and soil biology, encompassing topics such as the building blocks of the soil system and bioremediation of contaminated soils.

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer Nature. This book was released on 2021-05-20 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.

Download or read book Computational Economics Heterogeneous Agent Modeling written by Cars Hommes and published by Elsevier. This book was released on 2018-06-27 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Computational Economics: Heterogeneous Agent Modeling, Volume Four, focuses on heterogeneous agent models, emphasizing recent advances in macroeconomics (including DSGE), finance, empirical validation and experiments, networks and related applications. Capturing the advances made since the publication of Volume Two (Tesfatsion & Judd, 2006), it provides high-level literature with sections devoted to Macroeconomics, Finance, Empirical Validation and Experiments, Networks, and other applications, including Innovation Diffusion in Heterogeneous Populations, Market Design and Electricity Markets, and a final section on Perspectives on Heterogeneity. - Helps readers fully understand the dynamic properties of realistically rendered economic systems - Emphasizes detailed specifications of structural conditions, institutional arrangements and behavioral dispositions - Provides broad assessments that can lead researchers to recognize new synergies and opportunities

Download or read book Photosynthesis written by Harvey J.M. Hou and published by Elsevier. This book was released on 2023-07-27 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photosynthesis: From Plants to Nanomaterials in the Nanomaterial-Plant Interactions series, summarizes both the foundational mechanisms and latest advances in photosynthesis. With a strong emphasis on artificial photosynthesis, the book also analyzes the role of nanomaterials in energy production. Starting with an introduction to plant photosynthetic systems, chapters discuss the structure of light harvesting systems, energy transfer and membrane protein complexes. The book later describes the role of nanoparticles in photosynthesis, including agricultural applications, advances in nanobionics, and the impact of engineered nanomaterials. This book is an essential read for researchers and students interested in photosynthesis, bionanotechnology and nanomaterials. - Presents the latest advances in plant photosynthesis - Discusses the role of nanomaterials in energy production and other photosynthetic mechanisms - Highlights nanotechnology and artificial photosynthesis

Download or read book Science written by John Michels (Journalist) and published by . This book was released on 2003 with total page 1638 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cholesterol written by Anna N. Bukiya and published by Academic Press. This book was released on 2022-04-26 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Cholesterol, Drs. Anna Bukiya and Alex Dopico have compiled a comprehensive resource on biological and clinical aspects of cholesterol, spanning biophysics and biochemistry, as well as the latest pharmacological discoveries employed to tackle disorders associated with abnormal cholesterol levels. Early chapters on basic biology offer guidance in cholesterol lab chemistry, cholesterol metabolism and synthesis, molecular evolution of cholesterol and sterols, cholesterol peptides, and cholesterol modulation. Chapters on cellular and organismal development discuss cholesterol transport in blood, lipoproteins, and cholesterol metabolism; cholesterol detection in the blood; cellular cholesterol levels; hypercholesterolemia; and the role of cholesterol in early human development. Pathophysical specialists consider familial hypobetalipoproteinemia, critical illness and cholesterol levels, coronary artery disease, CESD, cholesterol and viral pathology, cholesterol and neurodegenerative disorders, and cholesterol and substance use disorders. A final section examines pharmacology of drug delivery systems targeting cholesterol related disorders, cholesterol receptors, cholesterol reduction, statins, citrate lyase, cyclodextrins, and clinical management. Cholesterol: From Biophysics and Biochemistry to Pathology and Pharmacology empowers researchers, students, and clinicians across various disciplines to advance new cholesterol-based studies, improve clinical management, and drive drug discovery. - Ties basic biology to clinical application and drug discovery - Provides methods and protocols for lab-based cholesterol research and clinical testing - Examines the latest pharmacological discoveries employed to tackle cholesterol related disorders - Includes chapter contributions from a wide range of specialists, uniting various disciplines

Download or read book Handbook of Forensic Science written by Jim Fraser and published by Routledge. This book was released on 2013-01-11 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic science has become increasingly important within contemporary criminal justice, from criminal investigation through to courtroom deliberations, and an increasing number of agencies and individuals are having to engage with its contribution to contemporary justice. This Handbook aims to provide an authoritative map of the landscape of forensic science within the criminal justice system of the UK. It sets out the essential features of the subject, covering the disciplinary, technological, organizational and legislative resources that are brought together to make up contemporary forensic science practice. It is the first full-length publication which reviews forensic science in a wider political, economic, social, technological and legal context, identifying emerging themes on the current status and potential future of forensic science as part of the criminal justice system. With contributions from many of the leading authorities in the field it will be essential reading for both students and practitioners.

Download or read book Advanced Heterogeneous Catalysts Volume 1 written by Sudarsanam Putla and published by ACS Symposium. This book was released on 2021-05-07 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances and applications of nanosized catalysts Over the last five years, tremendous advances have been made in heterogeneous catalysis. In particular, catalysts' design from the bulk to nano-scale (1-100 nm), with desirable active sites, has received great attention in current catalysis research with the aim to fill the gap between homogeneous and heterogeneous catalysis. This volume focuses on applications of nanosized catalysts. Articles describe characterization, synthesis, and applications in biomass conversion, auto-exhaust purification, selective oxidation/hydrogenation, syngas conversion, and other important reactions. Readers will find examples of catalysts designed to be tunable for specific outcomes, inspiring their research. Scientists and engineers in chemistry, materials science, nanotechnology, and chemical engineering will find this volume useful.