Download or read book Hepatic Plasma Proteins written by Barbara H. Bowman and published by Elsevier. This book was released on 2014-05-10 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.
Download or read book Production of Plasma and Tissue Proteins by Non hepatic Rat Organs as Studies with Lysine 6 C14 written by C. G. Bly and published by . This book was released on 1953 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plasma Protein Metabolism written by Marcus Rothschild and published by Elsevier. This book was released on 2012-12-02 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma Protein Metabolism: Regulation of Synthesis, Distribution, and Degradation covers the concepts concerning the physiological and pathophysiological factors regulating the distribution, degradation, and synthesis of plasma proteins. This book is organized into nine parts encompassing 32 chapters. The first parts present the assumptions and methodology involved in the various in vivo and in vitro techniques that provide insights to protein metabolism. The next parts describe the techniques of protein isolation, characterization, labeling, and mathematical analysis of the data, as well as the methods for directly quantitating protein synthetic rates in nonsteady state conditions. Other parts are devoted to the factors involved in regulating the serum levels of albumin, acute phase reactants, immunoglobulins, clotting factors, complement and hormone-binding proteins. The controlling factors include such general and specific physiological regulators of protein synthesis and catabolism as levels of specific serum proteins, hormonal regulators, variations of temperature and oncotic pressure, antigenic stimulation, and nutritional factors. The remaining parts analyze the pathophysiological factors including disorders of protein synthesis, distribution, exogenous catabolism, and external loss and stress that produce abnormal levels of serum proteins. This book is intended primarily intended to protein chemists and researchers.
Download or read book Plasma Protein Turnover written by Romano Bianchi and published by Springer. This book was released on 1976-06-18 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Biochemistry for Dentistry written by Anil Gupta and published by Springer. This book was released on 2018-12-30 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
Download or read book Structure and Function of Plasma Proteins written by A. Allison and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma proteins are of interest from many points of view. Biochemists have separated and purified numerous plasma proteins and studied their physical properties, aminoacid composition and sequence, the carbohydrate components of some, and binding of metals, hormones and other materials. Much work has also been carried out on the synthesis, rates of turnover and degradation of plasma proteins. Many plasma proteins show inherited variations, some of which (e.g. those of heptoglobins and transferrins) are common in various human populations while others (e.g. absence of lipoproteins or im munoglobins) are rare but important because of their association with clinical syndromes. Since blood is the most accessible bodily con stituent, geneticists have made good use of serum protein differences as genetic markers in family and population studies. Physiologists have long been interested in plasma proteins in relation to colloid osmotic pressure, transport of lipids, iron, hormones and other materials, the activities of renal glomeruli and tubules, the function of the liver, and many other bodily activities. Plasma proteins are also widely studied in relation to malnutrition and undernutrition, particularly that associated with defective intake of protein.
Download or read book The Plasma Proteins written by Paul G. Weil and published by . This book was released on 1959 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Function of Plasma Proteins written by A. Allison and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Ontogeny of Human Plasma Proteins: Detection of the Onset and Site of Synthesis Using Genetic Markers and in Vitro Cultures.- 1.1. Introduction.- 1.2. Immunoglobulins.- 1.2.1. Classes and Subclasses and Genetic Markers.- 1.2.2. Synthesis of Ig Molecules at Cellular Level.- 1.2.3. Transfer of Immunoglobulins through the Placenta.- 1.2.4. Synthesis of Immunoglobulins during Fetal Life.- 1.3. Complement.- 1.3.1. The Components of Complement.- 1.3.2. Levels and Fetal Synthesis of the Components of C.- 1.4. Haptoglobin System.- 1.5. Transferrins.- 1.6. ?-Lipoprotein Variants: The Ag and Lp System.
Download or read book Plasma proteins written by U Satyanarayana and published by Elsevier Health Sciences. This book was released on 2014-11-07 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma proteins Plasma proteins
Download or read book Clinical Hepatology written by G. Csomos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatology has come of age in the last decades. Biology of the liver has flour ished long before. As the largest homogeneous organ of the body the liver served as useful model in the development of biochemistry and related discip lines. Only gradually were these biological investigations applied to the clinical study of liver disease. This was particularly stimulated by the recognition that in the greater part of the world, the developing countries and what we now call the Third World, liver disease represents a major threat to overall public health. It leads to morbidity and mortality of persons in their productive years from liver cancer, cirrhosis and parasitic disease, particularly, schistosomiasis. Moreover, the growing emphasis on the social impact of diseases focused on disorders of the liver because malnutrition, poverty, and drug addiction contrib ute greatly to their spread. This is compounded by the increase of alcohol abuse, recently on the rise even in the developing countries. Concern with envi ronmental pollution has also raised the interest in liver diseases, in part because the liver acts as a guardian against polluting chemicals and in part because it is considered, possibly to an exaggerated degree, a vulnerable target of such chemicals.
Download or read book An Electrophoretic Study of Plasma Proteins in Liver Disease written by and published by . This book was released on 1949 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Liver Pathophysiology written by Pablo Muriel and published by Academic Press. This book was released on 2017-03-02 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Download or read book Pathophysiology of Plasma Protein Metabolism written by Giulian Mariant and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a factual account of the proceedings of an international symposium on the pathophysiology of plasma protein metabolism, which was organised in October 1982 by the Plasmaprotein and Immunology Division of the C.N.R. Institute of Clinical Physiology at the University of Pisa (Italy). Several of the contributors are former members of the International Study Group on Plasma Protein Metabolism, the last meeting of which was held in Turin (Italy) in 1974, under the auspices of the scientific organisation of the same institute. The symposium took the form of a series of lectures, with the main objective of providing a positive contribution to the state of the art of several topics related to the kinetic and pathophysiological factors regulating the synthesis, distribution and degradation of plasma proteins. The first four chapters form a group, each one considering a special aspect of the kinetics of turnover and distribution of plasma proteins in general; particular attention is paid to the recent advances in the field of kinetic modelling, the choice of the best models and the optimisation of the experimental designs. The next seven chapters consider the regulation of synthesis, distribution and catab olism of various classes of plasma proteins including albumin, immunoglobulins, complement fractions and acute-phase proteins. The remaining chapters deal with metabolic studies of various plasma proteins (including tumour markers, coagUlation proteins and lipoproteins) in different disease states, such as malig nancies, coagulative disorders, malnutrition and the extensive group of athero sclerotic cardiovascular diseases.
Download or read book Studies on the Role of the Liver in the Formation of the Plasma Proteins written by George Hugh Berryman and published by . This book was released on 1941 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Download or read book Albumin Structure Function and Uses written by Victor M. Rosenoer and published by Elsevier. This book was released on 2014-05-18 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.
Download or read book Osmosensing and Osmosignaling written by and published by Elsevier. This book was released on 2007-10-01 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of osmosensing and osmosignaling written by experts in the field.