Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Regulation of Tissue Oxygenation written by Roland N. Pittman and published by Morgan & Claypool. This book was released on 2016-08-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4-5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Hemoglobin and Oxygen Binding written by Chien Ho and published by North-Holland. This book was released on 1982 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.
Download or read book A Molecular Description of Oxygen Binding to Hemoglobin written by Barry Duane Olafson and published by . This book was released on 1979 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Blood Groups and Red Cell Antigens written by Laura Dean and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Hemoglobins written by Howard Franklin Bunn and published by W.B. Saunders Company. This book was released on 1977 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the dawn of the era of molecular biology, hemoglobin has been subjected to more scrutiny than any other protein, and Bunn, Forget, and Ranney can each lay claim to major contributions to the saga of hemoglobin. Their well-organized, comprehensive, and superbly illustrated work is an excellent review of the abnormal hemoglobin field. Early chapters deal with the structure and function of human hemoglobin and the way in which this is modified in various disease states. Later sections deal with the various structural hemoglobin variants and their associated clinical manifestations, the thalassaemias, and the acquired disorders of hemoglobin. The sections that deal with the modification of hemoglobin function in various disease states are particularly good. The book contains an extensive and up-to-date bibliography and is remarkably free from errors of fact or type--the best standard of reference on the subject as of the year 1977.
Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.
Download or read book Hemoglobin Disorders written by Ronald L. Nagel and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemoglobin and Hemoglobinologists This volume, Hemoglobin Disorders: Molecular Methods and Protocols, will be introduced with a review of the great milestones in the field, and the scientists responsible for those achievements. The history of hemoglobin can be divided into three periods: the Classical period, the Modern period, and the Post-Modern period. I am inclined to include as the four major members of the classical period Francis Roughton, Quentin Gibson, Jeffries Wyman, and Linus Pauling, not only because of their achievements, but also because of the superb scientists they trained and/or influenced. Francis John Worsely Roughton (1899–1972) (Fig. 1), in his laboratory at Trinity College in Cambridge, England, made the first measurements of the rapid reaction of oxygen with hemoglobin at the millisecond scale, at first by flow-mixing methods and later by flash photolysis. He not only opened an era of molecular research of hemoglobin, but also invented the methodology for fast reactions through the use of laser technology, which was later improved by others so that even faster reactions could be detected. Another contribution of Roughton was the education of Quentin H. Gibson (Fig. 2), his favorite s- dent, who, in his laboratory in Sheffield, continued to expand the horizon of ligand binding to hemoglobin, defining the oxygen binding constants for each of the hemes of hemoglobin. Though this did not, as expected, solve the und- lying mechanism of ligand cooperativity as discussed below, it was nonet- less an important milestone.
Download or read book Blood and Tissue Oxygen Carriers written by Charlotte P. Mangum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigations of the oxygen carriers range from the characterization of natural populations to measurements of tenths of nanometer distances between atoms. The scope is so great that few biologists and biochemists can fully comprehend the primary literature in its entirety. In addition, the findings of the past two or three decades have advanced the field so rapidly that a truly current account is not readily accessible to a general audience. In recognition of the problem a symposium was held and its proceedings published in the American Zoologist in 1980. Although it included several research reports, most of the contributions were intended to summarize then state-of-the-art information on molecular structure and respiratory function at a level that could be understood by biologists and biochemists who are not experts on our subject. Judging from the reprint requests with which the authors were inundated, the assessment of need had been accurate. I believe that the need for an update, which is wholly focused on communication to the general audience, is even greater in 1992. I therefore asked the authors of this volume to address individuals who might otherwise turn in vain to an advanced textbook of physiology or biochemistry. I have, of course, requested a more comprehensive coverage than would be possible in a general text, but one that is not more parochial. Just as textbooks differ vastly in the level at which their subject matter is presented, so the level of non-expertise was conceived differently by the contributors to this volume.
Download or read book Vertebrate and Invertebrate Respiratory Proteins Lipoproteins and other Body Fluid Proteins written by Ulrich Hoeger and published by Springer Nature. This book was released on 2020-03-18 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.
Download or read book Hemoglobin and Myoglobin in Their Reactions with Ligands written by Eraldo Antonini and published by North-Holland. This book was released on 1971 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physics Pharmacology and Physiology for Anaesthetists written by Matthew E. Cross and published by Cambridge University Press. This book was released on 2014-03-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.
Download or read book Hemoglobin and Oxygen Binding Ed by Chien Ho Etc written by Jian He and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hemoglobin Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics written by Hae Won Kim and published by Springer Science & Business Media. This book was released on 2013-12-18 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.
Download or read book Oxygen Complexes and Oxygen Activation by Transition Metals written by Arthur Martell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph consists of manuscripts, summary statements, and poster abstracts submitted by invited speakers and poster contributors who participated in the symposium "Oxygen Complexes and Oxygen Activation by Transition Metals," held March 23-26, 1987, at Texas A&M University. This meeting was the fifth annual international symposium sponsored by the Texas A&M Industry-University Cooperative Chemistry Program (IUCCP). The co chairmen of the conference were Professors Arthur E. Martell and Donald T. Sawyer of the Texas A&M University Chemistry Department. The program was developed by an academic-industrial steering committee consisting of the co-chairmen and members appointed by the sponsoring chemical companies Dr. James F. Bradzil, The Standard Oil Company, Ohio; Dr. Jerry R. Ebner, Monsanto Company; Dr. Craig Murchison, Dow Chemical Company; Dr. Donald C. Olsen, Shell Development Company; Dr. Tim R. Ryan, Celanese Chemical Company; and Dr. Ron Sanderson, Texaco Chemical Company. The subject of this conference reflects the intense interest that has developed in academic institutions and industry on several aspects of dioxygen chemistry. These include the formation of dioxygen complexes and their applications in facilitated transport and oxygen separation; homo geneous and heterogeneous catalysis of oxidation; and oxygenation of organic substrates by molecular oxygen. The conference differs in two respects from several other symposia on dioxygen chemistry held during the past few years. First, there is extensive industrial participation, especially with respect to oxygen activation.
Download or read book The Molecules of Life written by Kuriyan, John and published by W.W. Norton & Company. This book was released on 2012-07-25 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an integrated physical and biochemical foundation for undergraduate students majoring in biology or health sciences. It is particularly suitable for students planning to enter the pharmaceutical industry. This new generation of molecular biologists and biochemists will harness the tools and insights of physics and chemistry to exploit the emergence of genomics and systems-level information in biology, and will shape the future of medicine.
