Download or read book Hemoglobin acetaldehyde Adducts written by Pekka Sillanaukee and published by . This book was released on 1992 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acetaldehyde induced Changes of Hemoglobin and Immune Response Against Protein Acetaldehyde Adducts written by Aija Riikonen-Kyttälä and published by . This book was released on 1996 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acetaldehyde Adducts of Hemoglobin as a Possible Marker of Chronic Alcoholism written by Evanthia N. Diaconis and published by . This book was released on 1984 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aldehyde Adducts in Alcoholism written by Michael Aldis Collins and published by . This book was released on 1985 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acetaldehyde Related Pathology written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2007-04-30 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer’s. Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology. This book is essential reading for anyone interested in the effects of this compound - pathologists, biochemists, toxicologists, cell and molecular biologists.
Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2001 with total page 1254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders of Hemoglobin stands tall as the definitive work on the genetics, pathophysiology, and clinical management of hemoglobinopathies and thalassemia. Drs. Steinberg, Forget, Higgs, and Nagel have gathered the world authorities on the science and clinical management of these disorders and created the authoritative textbook for researchers and clinicians alike.Authors describe the scientific basis of clinical features and provide clinicians with a clear background of disorders they treat and scientists with an essential link between their research and its clinical manifestation. Disorders of Hemoglobin is the only single-source reference on hemoglobinopathies for hematologists, pediatricians, clinical investigators, and geneticists worldwide.
Download or read book Toxicology of the Liver written by Gabriel L Plaa and published by CRC Press. This book was released on 1998-02-27 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, micro
Download or read book Endogenous Toxins 2 Volume Set written by Peter J. O'Brien and published by John Wiley & Sons. This book was released on 2009-12-02 with total page 1043 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as a first-stop reference for researchers and professionals in toxicology, pharmacology and medicine, this handbook is the very first to tie together the knowledge from many disciplines that has so far been available only from widely dispersed sources in the primary literature. As such, it presents the complete picture on what is currently known about endogenous toxins, including their generation, mode of action, resulting disease condition, and available countermeasures. Clearly divided into four parts, the first systematically covers important toxic molecule species, including metabolic intermediates and reactive oxygen species. The second discusses the role of genetically determined metabolic malfunctions, such as galactosemia, hyperlipidemia, porphyria, hemochromatosis and related conditions, while part three looks at acquired and chronic diseases caused or exacerbated by endogenous toxins, such as hepatic injury, asthma, rheumatism, colorectal cancer, reperfusion diseases, neurodegneration and aging. The final part reviews currents strategies to control and minimize the effect of endogenous toxins, either by nutritional or pharmacological interventions. With its complete coverage integrating molecular and systemic aspects from the biochemical basis to human disease conditions, this comprehensive reference will appeal to a broad target group of toxicologists, biochemists, nutrition specialists and physicians.
Download or read book Alcoholism A Molecular Perspective written by T. Norman Palmer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected proceedings from the NATO Advanced Study Institute (AS I) "The Molecular Pathology of Alcoholism" held at the Hotel Il Ciocco in Tuscany during 26th August - 6th September 1990. Alcoholism remains one of the most challenging problems in medical care, with far-reaching medical, social and economic consequences. For example in the U. S. , estimates indicate that 18 million people have a serious drinking problem and that the total cost to the economy of alcohol abuse is $117 billion. Treatment of alcohol dependence and other alcohol-related disorders accounts for almost 15% of the total health bill of the United States. Despite the scale of the medical problem, biomedical research on alcoholism remains something of a 'Cinderella science'. Research funding from government and other bodies is relatively poor and the number of medical scientists working in the field remains small. The Organizing Committee for this NATO ASI, comprising Charles Lieber (New York), Timothy Peters (London), Mario Dianzani (Torino), Emanuele Albano (Torino) and Norman Palmer (perth, Director), were therefore particularly grateful to the NATO Scientific Affairs Division for their active support of this AS I, the first dealing with a topic related to alcohol abuse. We moreover hope that this support will continue. The theme of the ASI was an in depth discussion of the molecular events initiated by alcohol abuse that culminate in onset of alcohol-related disease.
Download or read book Ethanol and the Liver written by David Sherman and published by CRC Press. This book was released on 2002-05-30 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic scien
Download or read book The Pharmacology of Alcohol Abuse written by Henry R. Kranzler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of the book is the pharmacology of ethanol. It brings together the work of both basic and clinical investigators in the pharmacology of alcohol and alcohol abuse. The major focus is on the integration of findings from different levels of analysis, together with a discussion of recent insights from molecular biology in terms of their relevance for understanding ethanol's effects and the implications for the development of medications. Comprehensive in its scope, this book provides an up-to-date, in-depth treatment of the field, with particular emphasis on the integration of research findings from diverse approaches and how these findings might influence future investigations.
Download or read book Diagnosis of Alcohol Abuse written by Ronald Ross Watson and published by CRC Press. This book was released on 1989-07-31 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest methods used to diagnose alcoholism are discussed in this timely publication. Old systems are reviewed, and their efficacy in the diagnosis of alcoholism is analyzed. Laboratory methods that could improve the objectivity and accuracy of clinical tests are highlighted. Additionally, physical, psychological, and biochemical tests used to diagnose severe alcoholism are explored.
Download or read book Alcohol and Its Biomarkers written by Amitava Dasgupta and published by Elsevier. This book was released on 2015-02-18 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking
Download or read book Medical and Nutritional Complications of Alcoholism written by Charles S. Lieber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the Western world, alcohol is the most abused drug. recognized that a majority of patients with cirrhosis do For all the attention being directed toward heroin, co admit to excessive alcohol consumption. Other tissues caine, and marijuana, the favorite mood-altering drug in can also be severely affected, including brain, gut, the United States, as in almost every human society, is heart, endocrine systems, bone, blood, and muscle. A question often raised is, "In what way does an alcoholic alcohol. In nature, the fermentation of sugars is the differ from a nonalcoholic?" Inquiries have focused on major source of ethanol, but how humans first encoun tered it is unclear. It most likely occurred in either psychological make-up, behavioral differences, and socio fermented fruit juices (wine), fermented grain (beer), or economic factors. More recently, however, physical dif fermented honey (mead). Whether the Paleolithic Stone ferences have been delineated. Prior to the development Age man knew of ethanol is undetermined, but it is of various disease entities, chronic ethanol exposure abundantly clear that his Neolithic descendants were results in profound biochemical and morphological familiar with the product of fermentation. With the changes. Consequently, an alcoholic does not respond exception of the original inhabitants of Tierra del Fuego, normally to alcohol, other drugs, or even other toxic the Australian aborigines, and some polar tribes, all agents.
Download or read book Measuring Alcohol Consumption written by Raye Z. Litten and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Importance of Measuring Alcohol Consumption To date, alcohol studies have attended far more to issues of alco hol dependence and the harmful consequences of drinking than to the level of alcohol consumption itself. This is, perhaps, not surprising since dependence on alcohol is believed to constitute a meaningful and distinct medical syndrome, regardless of the level of alcohol consumption associated with it (Edwards and Gross, 1976). Also, of society is generally more concerned with the adverse consequences drinking (e. g. , traffic fatalities, homelessness, health care and legal expenses, and academiclbehavioral problems in young drinkers), than with the quantity of alcohol actually consumed. Nevertheless, accurate assessment of alcohol usage is important in its own right in at least four contexts: 1. Evaluating the effectiveness of alcoholism and alcohol abuse treatment and prevention efforts. Such efforts include both applied evaluations of existing programs and formal, well-controlled efficacy studies on experimental interventions. These investigations require rigorous methodologies to assess outcomes precisely and contrast what may be quite subtle differences between programs and between pre treatment and posttreatment outcomes. Although these studies are usually characterized by the employment of multiple measures of success-including general improvements in social and physical functioning, reduction in degree of dependence, and resolution of problems directly resultant from drinking-it is by their assessment of changes in drinking behavior that they are potentially able to achieve the highest level of objectivity and exactitude.
Download or read book Assessing Alcohol Problems written by John P. Allen and published by . This book was released on 2003 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Vinyl Acetate written by and published by . This book was released on 1992 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
