Download or read book Hargobind Khorana written by Nandini and published by Prabhat Prakashan. This book was released on 2021-01-01 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Biology Selected Papers Of H G Khorana With Introductions written by H Gobind Khorana and published by World Scientific. This book was released on 2000-05-24 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two chapters of this invaluable book trace the developments of the chemistry and macromolecular structures, respectively, of proteins and nuclei acids. Similarly, the introductions to the succeeding chapters review, step by step, the historical landmarks in the topics covered. These include discoveries of biological phosphate esters, nucleotides and nucleotide coenzymes (important in intermediary metabolism), the nature of the genetic material and biological synthesis of proteins, formulation of the problem of the genetic code, and perspectives on bioenergetics.The selected papers illustrate the developments of the chemical synthesis of nucleotides and nucleotide coenzymes of ribo- and deoxy-ribo-polynucleotides (RNA, DNA), of the total synthesis of genes in the laboratory, and principles for gene amplification (PCR). Another major section covers studies of enzymes that degrade nucleic acids, the structure of transfer RNA and its role in protein synthesis, and the author's work on the elucidation of the genetic code. Finally, there are descriptions of the studies on biological membranes and the membrane protein bacteriorhodopsin, a biological proton pump. These studies elucidated the mechanism of proton translocation, which is central to bioenergetics.
Download or read book Landmark Experiments in Molecular Biology written by Michael Fry and published by Academic Press. This book was released on 2016-06-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. - Includes detailed analysis of classically designed and executed experiments - Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries - Provides critical analysis of the history of molecular biology to inform the future of scientific discovery - Examines the machinery of inheritance and biological information handling
Download or read book Life s Greatest Secret written by Matthew Cobb and published by Hachette UK. This book was released on 2015-07-07 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life's secrets. Life's Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life's) future. Life's Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters -- mathematicians, physicists, information theorists, and biologists -- who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or "junk DNA" was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb's telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who'd like to explore those questions for themselves.
Download or read book Sources of Medical Technology written by Committee on Technological Innovation in Medicine and published by National Academies Press. This book was released on 1995-01-15 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Download or read book Membranes to Molecular Machines written by Mathias Grote and published by University of Chicago Press. This book was released on 2019-07-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences—from practitioner to historian to philosopher. The research described in the book and its central actor, Dieter Oesterhelt, were honored with the 2021 Albert Lasker Basic Medical Research Award for his contribution to the development of optogenetics.
Download or read book The Least Likely Man written by Franklin H. Portugal and published by MIT Press. This book was released on 2015-02-06 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: How unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code. The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Francis Crick. How did Nirenberg do it, and why is he so little known? In The Least Likely Man, Franklin Portugal tells the fascinating life story of a famous scientist that most of us have never heard of. Nirenberg did not have a particularly brilliant undergraduate or graduate career. After being hired as a researcher at the NIH, he quietly explored how cells make proteins. Meanwhile, Watson, Crick, and eighteen other leading scientists had formed the “RNA Tie Club” (named after the distinctive ties they wore, each decorated with one of twenty amino acid designs), intending to claim credit for the discovery of the genetic code before they had even worked out the details. They were surprised, and displeased, when Nirenberg announced his preliminary findings of a genetic code at an international meeting in Moscow in 1961. Drawing on Nirenberg's “lab diaries,” Portugal offers an engaging and accessible account of Nirenberg's experimental approach, describes counterclaims by Crick, Watson, and Sidney Brenner, and traces Nirenberg's later switch to an entirely new, even more challenging field. Having won the Nobel for his work on the genetic code, Nirenberg moved on to the next frontier of biological research: how the brain works.
Download or read book Comprehensive Biochemistry for Dentistry written by Anil Gupta and published by Springer. This book was released on 2018-12-30 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
Download or read book 20 Indians Who Changed the World written by Shruthi Rao and published by . This book was released on 2019-05-10 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: A brilliant collection of profiles of 20 trailblazing Indians who changed the world with their ideas, innovation and discoveries. For over 3000 years, the Indian subcontinent has contributed to fields as diverse as mathematics and science, spirituality and philosophy, as well as music and literature. In this absorbing book, Shruthi Rao profiles 20 legendary Indians who dared to think differently and changed the world--from starting a new religion based on the principles of compassion and peace; to creating the first set of rules for grammar; to discovering the existence of black holes, and so much more. 20 Indians Who Changed the World is as informative and well-researched as it is inspiring, a book every Indian can read with pride. Amartya Sen Ashoka Bhaskara II (Bhaskaracharya) Buddha C.V. Raman Faqir Chand Kohli Har Gobind Khorana Indra K. Nooyi Jawaharlal Nehru Kalpana Chawla Mohandas Karamchand Gandhi Mother Teresa Narinder Singh Kapany Pandit Ravi Shankar Panini Rabindranath Tagore Subrahmanyan Chandrasekhar Swami Vivekananda Tipu Sultan Venkatraman Ramakrishnan
Download or read book Primates written by Jim Ottaviani and published by Macmillan. This book was released on 2013-06-11 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fun and immersive look into the lives of the three greatest primatologists of the twentieth century: Biruté Galdikas, Dian Fossey, and Jane Goodall, from the #1 New York Times bestselling author of Feynman.
Download or read book Fred Sanger Double Nobel Laureate written by George G. Brownlee and published by Cambridge University Press. This book was released on 2020-04-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.
Download or read book Candid Science Ii Conversations With Famous Biomedical Scientists written by Istvan Hargittai and published by World Scientific. This book was released on 2002-03-15 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable book contains 36 interviews, including 26 with Nobel laureates. It presents a cross-section of biomedical science, a field that has been dominant in science for the past half century. The in-depth conversations cover important research areas and discoveries, as well as the roads to these discoveries, including aspects of the scientists' work that never saw publication. They also bring out the humanness of the famous scientists — the reader learns about their backgrounds, aspirations, failings, and triumphs. The book is illustrated with snapshots of the conversations and photos provided by the interviewees. It is a follow-up to the critically acclaimed Candid Science: Conversations with Famous Chemists, by the same author./a
Download or read book Essential Microbiology written by Stuart Hogg and published by John Wiley & Sons. This book was released on 2013-06-10 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Microbiology 2nd Edition is a fully revised comprehensive introductory text aimed at students taking a first course in the subject. It provides an ideal entry into the world of microorganisms, considering all aspects of their biology (structure, metabolism, genetics), and illustrates the remarkable diversity of microbial life by devoting a chapter to each of the main taxonomic groupings. The second part of the book introduces the reader to aspects of applied microbiology, exploring the involvement of microorganisms in areas as diverse as food and drink production, genetic engineering, global recycling systems and infectious disease. Essential Microbiology explains the key points of each topic but avoids overburdening the student with unnecessary detail. Now in full colour it makes extensive use of clear line diagrams to clarify sometimes difficult concepts or mechanisms. A companion web site includes further material including MCQs, enabling the student to assess their understanding of the main concepts that have been covered. This edition has been fully revised and updated to reflect the developments that have occurred in recent years and includes a completely new section devoted to medical microbiology. Students of any life science degree course will find this a concise and valuable introduction to microbiology.
Download or read book World Famous Scientists written by RAJEEV GARG and published by V&S Publishers. This book was released on 2012-11-15 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in simple and lucid language, these biographical sketches of great scientists have been put together for ready reference. History of the world is replete with such instances of such men and women who went against all the odds and achieved great heights and changed the shape of the world. In fact, reading about the life-sketch of a scientist and his achievements, has certainly great infotainment value. Besides, the lives of great men and women provide us inspiration to do things differently, and more confidently. For some people these inspirations have more importance than any other motivational factors. When we learn that Edison was a poor boy without any formal schooling or Faraday was an apprentice at a stationery shop we feel greatly motivated and think, 'if they could do it we can do it too!'. We find a new confidence in ourselves. In this respect the importance of these books, specially for children, can hardly be underestimated. Rather they could even be a part of the curriculum-- as at times they can prove so inspiring and motivate a person in such a way, that they could change the entire course of the life of a person. The main aim of this series is to expand the mental horizons of our readers and motivate them to achieve great heights in life. It is certainly a very valuable addition to the literature of popular science. The book can also prove to be an ideal companion during leisure time. #v&spublishers
Download or read book Asian Americans 3 Volumes written by Xiaojian Zhao and published by Greenwood. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive and up-to-date reference work on Asian Americans, comprising three volumes that address a broad range of topics on various Asian and Pacific Islander American groups from 1848 to the present day. This three-volume work represents a leading reference resource for Asian American studies that gives students, researchers, librarians, teachers, and other interested readers the ability to easily locate accurate, up-to-date information about Asian ethnic groups, historical and contemporary events, important policies, and notable individuals. Written by leading scholars in their fields of expertise and authorities in diverse professions, the entries devote attention to diverse Asian and Pacific Islander American groups as well as the roles of women, distinct socioeconomic classes, Asian American political and social movements, and race relations involving Asian Americans. Presents information on Asian Americans and individual Asian ethnic groups that provides comprehensive overviews of the respective groups Includes special topic entries that contain source information regarding major historical events Comprises work from a truly outstanding list of contributors that include scholars, journalists, writers, community activists, graduate students, and other specialists Expands the boundaries of Asian American studies through innovative entries that address transnationalism, gender and sexuality, and inter- and cross-disciplinarity
Download or read book The Origin and Evolution of the Genetic Code 100th Anniversary Year of the Birth of Francis Crick written by Koji Tamura and published by MDPI. This book was released on 2018-03-23 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "The Origin and Evolution of the Genetic Code: 100th Anniversary Year of the Birth of Francis Crick" that was published in Life
Download or read book Exploring Integrated Science written by Belal E. Baaquie and published by CRC Press. This book was released on 2009-12-01 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why is rubber elastic? Why are leaves green? Why can a gecko climb a wall? Answering these and a myriad of other puzzles of nature, Exploring Integrated Science shows how the simplest questions that arise from our daily experiences can lead us through a chain of reasoning that explains some of the most fascinating principles of science.Written in a
