Download or read book Handbook of teratology written by F. Clarke Fraser and published by . This book was released on 1977 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Teratology written by James G. Wilson and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Teratology written by James Graves Wilson and published by . This book was released on 1977 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Behavioral Teratology written by E.P. Riley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was developed in response to a need in behavioral teratology for a comprehen sive set of reviews of the field's many topics brought together in a single source. This volume represents the first effort to synthesize and integrate research in the field since 1969 when Justin Joffe wrote Prenatal Determinants of Behaviour. Joffe's book became a standard reference for many years, particularly for the experimental design of animal investigations. It has become increasingly evident, however, that some aspects of design once considered inviolate have changed and become part of a more flexible approach. In current research the emphasis is on a set of prioritized, but focused, experimental ques tions rather than on designs which factor all possible variables into every experiment. Also, new design considerations have arisen over the last 15 years, not appreciated when Joffe wrote. Moreover, the sheer volume of new experimental evidence generated since 1969 has increased the content of the field several fold. These considerations made a new review and critical appraisal of the field compelling. The book is divided into four major sections. Part I contains four chapters. These chapters provide discussions of the general principles of behavioral teratogenesis, and information on the historical, governmental, and methodological contexts in which the field operates. The purpose of these chapters is to provide the framework within which the review chapters in the remainder of the book may best be understood.

Download or read book Mechanisms and Pathogenesis written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Teratology written by C.L. Berry and published by Springer. This book was released on 2011-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fifteen years since the thalidomide disaster teratology has become a science in its own right, distinct from its progenitors, experimental embryology and develop mental biology, but bearing many of the familiar features of both parents. In this growth period there have been contributions from many different scientific disciplines as diverse as molecular biology and obstetrics, which have united in the field of study of congenital malformations. Scientists in academic departments, government research institutes and industrial pharmacology have all explored ways of evaluating the potential of drugs and chem icals to damage the embryo; strict methods of screening for teratogenicity have be come mandatory in most parts of the world. Despite a wealth of basic information in the fields of genetics and embryology, there is little concrete knowledge of the causal mechanisms of malformation in Man, and even less concerning the relevance to Man of those laboratory and animal tests which decide the fate of potentially useful drugs. It is timely, therefore, that in 1975 a group of young and active sci entists and clinicians concerned with the broader implications of teratology should review the past and look to the future of this emerging speciality. In this volume the editors have blended the opinions of teratologists; their message presages change in many of the old and accepted areas of investigative teratology.

Download or read book Research Procedures and Data Analysis written by James Wilson and published by Springer. This book was released on 1978-07-01 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Teratology Research procedures and data analysis written by James Graves Wilson and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Basic Concepts in Teratology written by T. V. N. Persaud and published by Alan R. Liss. This book was released on 1985 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Teratogenesis and Reproductive Toxicology written by E.M. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several disoiplines such as developmental and molecu lar biology, pathology, pharmacology and toxicology, pediatrics and neonatology, and epidemiology. More recently we h~ve seen an emergence of interest in other fields such as perinatal physiology and postnatal behavior which have now become incorporated into the mainstream of research in this discipline. The present volume is an effort to provide a sampling of concepts currently under active investigation in several of the above fields. The authors have endeavored to provide up-to-date in formation on the following topics: detection and analysis of potential hazards to the conceptus in the workplace, pharmacokinetic aspects of the maternal/placental! fetal complex and its relationship to human birth defects, and probable mechanisms of teratogenesis as uncovered in certain well-defined situations. Also included are summaries of newer investigations on the emerging field of postnatal functional evaluations, i. e. , adverse effects on adult activities resultant from in utero exposure to toxic substances.

Download or read book Comparative Maternal and Epidemiologic Aspects written by James Wilson and published by Springer. This book was released on 1977-12-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.

Download or read book Handbook of Life Course Health Development written by Neal Halfon and published by Springer. This book was released on 2017-11-20 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

Download or read book Drugs During Pregnancy and Lactation written by Christof Schaefer and published by Academic Press. This book was released on 2014-09-17 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs During Pregnancy and Lactation, Third Edition is a quick and reliable reference for all those working in disciplines related to fertility, pregnancy, lactation, child health and human genetics who prescribe or deliver medicinal products, and to those who evaluate health and safety risks. Each chapter contains twofold information regarding drugs that are appropriate for prescription during pregnancy and an assessment of the risk of a drug when exposure during pregnancy has already occurred. Thoroughly updated with current regulations, references to the latest pharmacological data, and new medicinal products, this edition is a comprehensive resource covering latest knowledge and findings related to drugs during lactation and pregnancy. Provides evidence-based recommendations to help clinicians make appropriate recommendations Uniquely organized and structured according to drug class and treatment indications to offer authoritative clinical content on potential adverse effects Highlights new research developments from primary source about working mechanism of substances that cause developmental disorders

Download or read book Handbook of Psychodynamic Approaches to Psychopathology written by Patrick Luyten and published by Guilford Publications. This book was released on 2017-05-04 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative and comprehensive, this volume provides a contemporary psychodynamic perspective on frequently encountered psychological disorders in adults, children, and adolescents. Leading international authorities review the growing evidence base for psychoanalytic theories and therapeutic models. Chapters examine the etiology and psychological mechanisms of each disorder and thoroughly describe effective treatment strategies. Highly accessible, the book is richly illustrated with clinical case material. It demonstrates ways in which psychodynamic theory and therapy are enhanced by integrating ideas and findings from neuroscience, social and personality psychology, cognitive-behavioral therapy, and other fields. Winner?Goethe Award for Psychoanalytic and Psychodynamic Scholarshipÿ

Download or read book The Cambridge Handbook of Environment in Human Development written by Linda Mayes and published by Cambridge University Press. This book was released on 2012-08-27 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Families, communities and societies influence children's learning and development in many ways. This is the first handbook devoted to the understanding of the nature of environments in child development. Utilizing Urie Bronfenbrenner's idea of embedded environments, this volume looks at environments from the immediate environment of the family (including fathers, siblings, grandparents and day-care personnel) to the larger environment including schools, neighborhoods, geographic regions, countries and cultures. Understanding these embedded environments and the ways in which they interact is necessary to understand development.

Download or read book The Oxford Handbook of Clinical Child and Adolescent Psychology written by Thomas H. Ollendick and published by Oxford University Press. This book was released on 2018-11-13 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the founding in 1896 of the first psychological clinic dedicated to children and adolescents, the study of the psychological treatment of young people lagged behind that of adults, and the basic psychopathology underlying mental disorders in this population was largely ignored. Since those early days, the field has evolved steadily and, in recent years, exponentially. The Oxford Handbook of Clinical Child and Adolescent Psychology is a state-of-the-science volume providing comprehensive coverage of the psychological problems and disorders of childhood. International in scope and penned by the discipline's most eminent scientists and practitioners, the handbook begins with a section on conceptual and empirical issues, followed by exceptional content on specific psychiatric disorders such as intellectual disability, externalizing and internalizing disorders, communication disorders, schizophrenia and bipolar disorder, personality disorders, and many more. The third section offers chapters on special problems in childhood and adolescence, including divorce, the incarceration of parents, suicide and non-suicidal self-injury, bullying, and medical illness. A fourth section covers delivery of clinical services in diverse settings, such as schools and prisons, and the handbook concludes with several chapters on emerging trends and future directions for the field. Conceptually rich and evidence-based, this handbook is an essential resource for students, practitioners, and researchers, providing a cutting-edge compendium of the latest theoretical and empirical developments by leaders of the discipline.

Download or read book Oxford Handbook of Obstetrics and Gynaecology written by Sally Collins and published by Oxford University Press, USA. This book was released on 2008-12-11 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a quick reference guide to the specialty, covering diagnoses, investigation and management in a user-friendly, accessible format. Contributors provide evidence-based guidelines which highlight the core knowledge for diagnosing and managing common problems and emergencies.