Download or read book Handbook of Myocardial Revascularization and Angiogenesis written by Stephen E Epstein and published by CRC Press. This book was released on 1999-09-23 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid development of myocardial revascularization from angioplasty to stents, and now to new laser technology has meant that there is an abundance of information available which has not been distilled into a user-friendly format. Confusion exists as to where we are with angiogenesis: what can it do? how do we do it? what is acceptable as a satisfactory result? Drs Kornowski, Epstein and Leon answer the need for a concise reference on the subject. They have assembled a team of internationally-recognised experts who are at the forefront of research and clinical application on myocardial revascularization and angiogenesis. They examine direct, transmyocardial and percutaneous approaches to revascularization. In the latter part of the Handbook, there is discussion about growth factors protein and gene therapy which should serve as a guide and provide background facts so as to ensure greater informational access to the interventional cardiologist.
Download or read book Angiogenesis and Direct Myocardial Revascularization 2005 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Myocardial Revascularization written by George S. Abela and published by Wiley-Liss. This book was released on 2002 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The percutaneous method of transluminal myocardial revascularization has roused enthusiasm in the field of cardiology because it is minimally invasive and relatively inexpensive. In his progressive new book, George Abela, a widely recognized pioneer in cardiology and lasers, has brought together the expertise of international leaders on the subject in this premier reference, Myocardial Revascularization: Novel Percutaneous Approaches. This resource provides interventional cardiologists, technical personnel and nurses in cardiac catheterization labs with the most current scholarly and clinical information available, including: * A historical overview of myocardial revascularization (including the Vineberg procedure and the more recent TMR/PMR procedures) * Biological responses and mechanisms of action in myocardial revascularization using mechanical, laser, ultrasound, and cryoenergy * Current technology for the percutaneous method of the procedure * Descriptions of other novel approaches including percutaneous in situ coronary venous arterialization * Discussion of results from preliminary and advanced TMR/PMR in canine and human procedures * Examination of various catheter navigation systems and potential adjunct gene therapies * Myocyte transplantation to replenish the depleted myocardium * Insights into the economics of these novel percutaneous techniques
Download or read book Angiogenesis and Direct Myocardial Revascularization written by Roger J. Laham and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Download or read book The AHA Clinical Cardiac Consult written by J. V. Nixon and published by Lippincott Williams & Wilkins. This book was released on 2010-10-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ideal source of fast, reliable guidance on diagnosis and management of both common and rare cardiovascular problems, this handbook covers more than 170 problems, diseases, syndromes, and chief complaints in the popular, easy-to-read, two-page 5-Minute Consult format.
Download or read book An Essential Guide to Cardiac Cell Therapy written by Emerson Perin and published by CRC Press. This book was released on 2006-09-15 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.
Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Download or read book Texas Heart Institute Journal written by and published by . This book was released on 2000 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Local Drug Delivery for Coronary Artery Disease written by Edoardo Camenzind and published by CRC Press. This book was released on 2005-06-14 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restenosis remains the Achilles heel of Percutaneous Coronary Interventions. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response, and drug eluting stents-using the stent as a platform for local drug delivery-are now considered a significant breakthrough in interventional cardiology. Pioneers in the field, the editors of Local Drug Delivery for Coronary Artery Disease have assembled an excellent team of contributors who offer their experience with threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. They share their expertise on all aspects of the field, including a discussion of results from preclinical and clinical studies, and they examine alternative methods of molecular delivery to the vessel wall. With coverage of the most current methods and applications, as well as a host of photographs illustrating their implementation, this book will serve as an excellent reference for cardiologists, pharmacologists, cardiac surgeons, and trainees.
Download or read book Cardiac Drug Development Guide written by Michael K. Pugsley and published by Springer Science & Business Media. This book was released on 2008-02-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and molecular aspects of therapeutic drug development. The chapters comprise a broad spectrum of therapeutic areas and hence involve a comprehensive discussion of molecular, biochemical, and electrophy- ological concepts based on years of in vitro as well as in vivo pharmacological st- ies. In addition, the latter part of the book includes comprehensive clinical cardiac chapters that describe important topics in molecular medicine. These chapters also discuss current clinical therapeutic trends in medicine and provide an evaluation of the efficacy of novel drugs in these areas. Cardiac Drug Development Guide has many distinctive and outstanding features that set it apart from other cardiac pharmacology books. This book introduces topics in an easily understandable format for researchers in many varying disciplines by integrating and thereby simplifying concepts not usually discussed across a broad range of cardiac disciplines and in a highly technical field. Each chapter not only introduces and describes the physiology, pharmacology, and pathophysiology of the disease, but also overviews the clinical implications of drug development, what stages these areas are currently in, and also reviews some of the methodologies involved in drug discovery and development. As a result, this book provides a comprehensive overview of the most advanced procedures in cardiac pharmacology today.
Download or read book Handbook of Complex Percutaneous Carotid Intervention written by Jacqueline Saw and published by Springer Science & Business Media. This book was released on 2008-08-17 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook supplements hands-on training in interventional cardiology with a specific focus on percutaneous intervention in patients with extracranial carotid artery stenosis. It carries reviews of landmark studies supporting carotid endarectomy and stenting and is a comprehensive guide to this exciting and burgeoning field.
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book The Handbook of Nanomedicine written by Kewal K. Jain and published by Humana Press. This book was released on 2017-03-20 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.
Download or read book Myocardial Laser Revascularization written by Charles Bridges and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, there is a dependable guide to transmyocardial laser revasculariztion (TMR). In this groundbreaking volume, clinicians who pioneered the use of this innovative treatment share their insights on the indications, results, mechanisms, and limitations of the technique. Under the careful editorial guidance of Drs. Bridges, Horvath, and Chiu, contributing authors explain: the evolution, science, rationale, and limitations for TMR how to select suitable candidates anesthetic considerations and the role of transesophageal echo TMR as a sole or combination therapy Whether you are already practicing TMR or contemplating its addition to your therapeutic armamentarium, this concise reference will answer all your questions about this important new procedure.
Download or read book Handbook of Cardiac Anatomy Physiology and Devices written by Paul A. Iaizzo and published by Springer Science & Business Media. This book was released on 2010-03-11 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revolution began in my professional career and education in 1997. In that year, I visited the University of Minnesota to discuss collaborative opportunities in cardiac anatomy, physiology, and medical device testing. The meeting was with a faculty member of the Department of Anesthesiology, Professor Paul Iaizzo. I didn’t know what to expect but, as always, I remained open minded and optimistic. Little did I know that my life would never be the same. . . . During the mid to late 1990s, Paul Iaizzo and his team were performing anesthesia research on isolated guinea pig hearts. We found the work appealing, but it was unclear how this research might apply to our interest in tools to aid in the design of implantable devices for the cardiovascular system. As discussions progressed, we noted that we would be far more interested in reanimation of large mammalian hearts, in particular, human hearts. Paul was confident this could be accomplished on large hearts, but thought that it would be unlikely that we would ever have access to human hearts for this application. We shook hands and the collaboration was born in 1997. In the same year, Paul and the research team at the University of Minnesota (including Bill Gallagher and Charles Soule) reanimated several swine hearts. Unlike the previous work on guinea pig hearts which were reanimated in Langendorff mode, the intention of this research was to produce a fully functional working heart model for device testing and cardiac research.
Download or read book The Collateral Circulation of the Heart written by Wolfgang Schaper and published by . This book was released on 1971 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Vessels for the Heart written by Thomas Joseph Stegmann and published by Cardiovascular Biotherapeutics Incorporated. This book was released on 2005 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
