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Book Handbook of Machine Learning Applications for Genomics

Download or read book Handbook of Machine Learning Applications for Genomics written by Sanjiban Sekhar Roy and published by Springer Nature. This book was released on 2022-06-23 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.

Book Machine Learning and Systems Biology in Genomics and Health

Download or read book Machine Learning and Systems Biology in Genomics and Health written by Shailza Singh and published by Springer Nature. This book was released on 2022-02-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. It discusses how systems biology is exploited in identifying the genetic markers for drug discovery and disease identification. Myriad number of diseases whether be infectious, metabolic, cancer can be dealt in effectively which combines the different omics data for precision medicine. Major breakthroughs in the field would help reflect more new innovations which are at their pinnacle stage. This book is useful for researchers in the fields of genomics, genetics, computational biology and bioinformatics.

Book Computational Genomics with R

Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Book Machine Learning Methods for Multi Omics Data Integration

Download or read book Machine Learning Methods for Multi Omics Data Integration written by Abedalrhman Alkhateeb and published by Springer Nature. This book was released on 2023-12-15 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advancement of biomedical engineering has enabled the generation of multi-omics data by developing high-throughput technologies, such as next-generation sequencing, mass spectrometry, and microarrays. Large-scale data sets for multiple omics platforms, including genomics, transcriptomics, proteomics, and metabolomics, have become more accessible and cost-effective over time. Integrating multi-omics data has become increasingly important in many research fields, such as bioinformatics, genomics, and systems biology. This integration allows researchers to understand complex interactions between biological molecules and pathways. It enables us to comprehensively understand complex biological systems, leading to new insights into disease mechanisms, drug discovery, and personalized medicine. Still, integrating various heterogeneous data types into a single learning model also comes with challenges. In this regard, learning algorithms have been vital in analyzing and integrating these large-scale heterogeneous data sets into one learning model. This book overviews the latest multi-omics technologies, machine learning techniques for data integration, and multi-omics databases for validation. It covers different types of learning for supervised and unsupervised learning techniques, including standard classifiers, deep learning, tensor factorization, ensemble learning, and clustering, among others. The book categorizes different levels of integrations, ranging from early, middle, or late-stage among multi-view models. The underlying models target different objectives, such as knowledge discovery, pattern recognition, disease-related biomarkers, and validation tools for multi-omics data. Finally, the book emphasizes practical applications and case studies, making it an essential resource for researchers and practitioners looking to apply machine learning to their multi-omics data sets. The book covers data preprocessing, feature selection, and model evaluation, providing readers with a practical guide to implementing machine learning techniques on various multi-omics data sets.

Book Deep Learning Applications in Image Analysis

Download or read book Deep Learning Applications in Image Analysis written by Sanjiban Sekhar Roy and published by Springer Nature. This book was released on 2023-07-08 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides state-of-the-art coverage of deep learning applications in image analysis. The book demonstrates various deep learning algorithms that can offer practical solutions for various image-related problems; also how these algorithms are used by scientists and scholars in industry and academia. This includes autoencoder and deep convolutional generative adversarial network in improving classification performance of Bangla handwritten characters, dealing with deep learning-based approaches using feature selection methods for automatic diagnosis of covid-19 disease from x-ray images, imbalance image data sets of classification, image captioning using deep transfer learning, developing a vehicle over speed detection system, creating an intelligent system for video-based proximity analysis, building a melanoma cancer detection system using deep learning, plant diseases classification using AlexNet, dealing with hyperspectral images using deep learning, chest x-ray image classification of pneumonia disease using efficient net and inceptionv3. The book also addresses the difficulty of implementing deep learning in terms of computation time and the complexity of reasoning and modelling different types of data where information is currently encoded. Each chapter has the application of various new or existing deep learning models such as Deep Neural Network (DNN) and Deep Convolutional Neural Networks (DCNN). The detailed utilization of deep learning packages that are available in MATLAB, Python and R programming environments have also been discussed, therefore, the readers will get to know about the practical implementation of deep learning as well. The content of this book is presented in a simple and lucid style for professionals, nonprofessionals, scientists, and students interested in the research area of deep learning applications in image analysis.

Book Applications of Machine Learning and Deep Learning on Biological Data

Download or read book Applications of Machine Learning and Deep Learning on Biological Data written by Faheem Masoodi and published by CRC Press. This book was released on 2023-03-13 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The automated learning of machines characterizes machine learning (ML). It focuses on making data-driven predictions using programmed algorithms. ML has several applications, including bioinformatics, which is a discipline of study and practice that deals with applying computational derivations to obtain biological data. It involves the collection, retrieval, storage, manipulation, and modeling of data for analysis or prediction made using customized software. Previously, comprehensive programming of bioinformatical algorithms was an extremely laborious task for such applications as predicting protein structures. Now, algorithms using ML and deep learning (DL) have increased the speed and efficacy of programming such algorithms. Applications of Machine Learning and Deep Learning on Biological Data is an examination of applying ML and DL to such areas as proteomics, genomics, microarrays, text mining, and systems biology. The key objective is to cover ML applications to biological science problems, focusing on problems related to bioinformatics. The book looks at cutting-edge research topics and methodologies in ML applied to the rapidly advancing discipline of bioinformatics. ML and DL applied to biological and neuroimaging data can open new frontiers for biomedical engineering, such as refining the understanding of complex diseases, including cancer and neurodegenerative and psychiatric disorders. Advances in this field could eventually lead to the development of precision medicine and automated diagnostic tools capable of tailoring medical treatments to individual lifestyles, variability, and the environment. Highlights include: Artificial Intelligence in treating and diagnosing schizophrenia An analysis of ML’s and DL’s financial effect on healthcare An XGBoost-based classification method for breast cancer classification Using ML to predict squamous diseases ML and DL applications in genomics and proteomics Applying ML and DL to biological data

Book Advanced AI Techniques and Applications in Bioinformatics

Download or read book Advanced AI Techniques and Applications in Bioinformatics written by Loveleen Gaur and published by CRC Press. This book was released on 2021-10-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advanced AI techniques are essential for resolving various problematic aspects emerging in the field of bioinformatics. This book covers the recent approaches in artificial intelligence and machine learning methods and their applications in Genome and Gene editing, cancer drug discovery classification, and the protein folding algorithms among others. Deep learning, which is widely used in image processing, is also applicable in bioinformatics as one of the most popular artificial intelligence approaches. The wide range of applications discussed in this book are an indispensable resource for computer scientists, engineers, biologists, mathematicians, physicians, and medical informaticists. Features: Focusses on the cross-disciplinary relation between computer science and biology and the role of machine learning methods in resolving complex problems in bioinformatics Provides a comprehensive and balanced blend of topics and applications using various advanced algorithms Presents cutting-edge research methodologies in the area of AI methods when applied to bioinformatics and innovative solutions Discusses the AI/ML techniques, their use, and their potential for use in common and future bioinformatics applications Includes recent achievements in AI and bioinformatics contributed by a global team of researchers

Book Bioinformatics  second edition

Download or read book Bioinformatics second edition written by Pierre Baldi and published by MIT Press. This book was released on 2001-07-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to machine learning approaches and their application to the analysis of biological data. An unprecedented wealth of data is being generated by genome sequencing projects and other experimental efforts to determine the structure and function of biological molecules. The demands and opportunities for interpreting these data are expanding rapidly. Bioinformatics is the development and application of computer methods for management, analysis, interpretation, and prediction, as well as for the design of experiments. Machine learning approaches (e.g., neural networks, hidden Markov models, and belief networks) are ideally suited for areas where there is a lot of data but little theory, which is the situation in molecular biology. The goal in machine learning is to extract useful information from a body of data by building good probabilistic models—and to automate the process as much as possible. In this book Pierre Baldi and Søren Brunak present the key machine learning approaches and apply them to the computational problems encountered in the analysis of biological data. The book is aimed both at biologists and biochemists who need to understand new data-driven algorithms and at those with a primary background in physics, mathematics, statistics, or computer science who need to know more about applications in molecular biology. This new second edition contains expanded coverage of probabilistic graphical models and of the applications of neural networks, as well as a new chapter on microarrays and gene expression. The entire text has been extensively revised.

Book Machine Learning Applications in Integrative Cancer Genomics

Download or read book Machine Learning Applications in Integrative Cancer Genomics written by and published by . This book was released on 2015 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Machine Learning Approaches to Bioinformatics

Download or read book Machine Learning Approaches to Bioinformatics written by Zheng Rong Yang and published by World Scientific. This book was released on 2010 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of subjects in applying machine learning approaches for bioinformatics projects. The book succeeds on two key unique features. First, it introduces the most widely used machine learning approaches in bioinformatics and discusses, with evaluations from real case studies, how they are used in individual bioinformatics projects. Second, it introduces state-of-the-art bioinformatics research methods. Furthermore, the book includes R codes and example data sets to help readers develop their own bioinformatics research skills. The theoretical parts and the practical parts are well integrated for readers to follow the existing procedures in individual research. Unlike most of the bioinformatics textbooks on the market, the content coverage is not limited to just one subject. A broad spectrum of relevant topics in bioinformatics including systematic data mining and computational systems biology researches are brought together in this book, thereby offering an efficient and convenient platform for undergraduate/graduate teaching. An essential textbook for both final year undergraduates and graduate students in universities, as well as a comprehensive handbook for new researchers, this book will also serve as a practical guide for software development in relevant bioinformatics projects.

Book Genomics at the Nexus of AI  Computer Vision  and Machine Learning

Download or read book Genomics at the Nexus of AI Computer Vision and Machine Learning written by Shilpa Choudhary and published by Wiley-Scrivener. This book was released on 2024-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a comprehensive understanding of cutting-edge research and applications at the intersection of genomics and advanced AI techniques and serves as an essential resource for researchers, bioinformaticians, and practitioners looking to leverage genomics data for AI-driven insights and innovations. The book encompasses a wide range of topics, starting with an introduction to genomics data and its unique characteristics. Each chapter unfolds a unique facet, delving into the collaborative potential and challenges that arise from advanced technologies. It explores image analysis techniques specifically tailored for genomic data. It also delves into deep learning showcasing the power of convolutional neural networks (CNN) and recurrent neural networks (RNN) in genomic image analysis and sequence analysis. Readers will gain practical knowledge on how to apply deep learning techniques to unlock patterns and relationships in genomics data. Transfer learning, a popular technique in AI, is explored in the context of genomics, demonstrating how knowledge from pre-trained models can be effectively transferred to genomic datasets, leading to improved performance and efficiency. Also covered is the domain adaptation techniques specifically tailored for genomics data. The book explores how genomics principles can inspire the design of AI algorithms, including genetic algorithms, evolutionary computing, and genetic programming. Additional chapters delve into the interpretation of genomic data using AI and ML models, including techniques for feature importance and visualization, as well as explainable AI methods that aid in understanding the inner workings of the models. The applications of genomics in AI span various domains, and the book explores AI-driven drug discovery and personalized medicine, genomic data analysis for disease diagnosis and prognosis, and the advancement of AI-enabled genomic research. Lastly, the book addresses the ethical considerations in integrating genomics with AI, computer vision, and machine learning. Audience The book will appeal to biomedical and computer/data scientists and researchers working in genomics and bioinformatics seeking to leverage AI, computer vision, and machine learning for enhanced analysis and discovery; healthcare professionals advancing personalized medicine and patient care; industry leaders and decision-makers in biotechnology, pharmaceuticals, and healthcare industries seeking strategic insights into the integration of genomics and advanced technologies.

Book Modeling and Applications in Operations Research

Download or read book Modeling and Applications in Operations Research written by Jyotiranjan Nayak and published by CRC Press. This book was released on 2023-11-29 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text envisages novel optimization methods that significantly impact real-life problems, starting from inventory control to economic decision-making. It discusses topics such as inventory control, queueing models, timetable scheduling, fuzzy optimization, and the Knapsack problem. The book’s content encompass the following key aspects: Presents a new model based on an unreliable server, wherein the convergence analysis is done using nature-inspired algorithms. Discusses the optimization techniques used in transportation problems, timetable problems, and optimal/dynamic pricing in inventory control. Highlights single and multi-objective optimization problems using pentagonal fuzzy numbers. Illustrates profit maximization inventory model for non-instantaneous deteriorating items with imprecise costs. Showcases nature-inspired algorithms such as particle swarm optimization, genetic algorithm, bat algorithm, and cuckoo search algorithm. The text covers multi-disciplinary real-time problems such as fuzzy optimization of transportation problems, inventory control with dynamic pricing, timetable problem with ant colony optimization, knapsack problem, queueing modeling using the nature-inspired algorithm, and multi-objective fuzzy linear programming. It showcases a comparative analysis for studying various combinations of system design parameters and default cost elements. It will serve as an ideal reference text for graduate students and academic researchers in the fields of industrial engineering, manufacturing engineering, production engineering, mechanical engineering, and mathematics.

Book Hybrid Computational Intelligent Systems

Download or read book Hybrid Computational Intelligent Systems written by Siddhartha Bhattacharyya and published by CRC Press. This book was released on 2023-05-03 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hybrid Computational Intelligent Systems – Modeling, Simulation and Optimization unearths the latest advances in evolving hybrid intelligent modeling and simulation of human-centric data-intensive applications optimized for real-time use, thereby enabling researchers to come up with novel breakthroughs in this ever-growing field. Salient features include the fundamentals of modeling and simulation with recourse to knowledge-based simulation, interaction paradigms, and human factors, along with the enhancement of the existing state of art in a high-performance computing setup. In addition, this book presents optimization strategies to evolve robust and failsafe intelligent system modeling and simulation. The volume also highlights novel applications for different engineering problems including signal and data processing, speech, image, sensor data processing, innovative intelligent systems, and swarm intelligent manufacturing systems. Features: A self-contained approach to integrating the principles of hybrid computational ntelligence with system modeling and simulation Well-versed foundation of computational intelligence and its application to real life engineering problems Elucidates essential background, concepts, definitions, and theories thereby putting forward a complete treatment on the subject Effective modeling of hybrid intelligent systems forms the backbone of almost every operative system in real-life Proper simulation of real-time hybrid intelligent systems is a prerequisite for deriving any real-life system solution Optimized system modeling and simulation enable real-time and failsafe operations of the existing hybrid intelligent system solutions Information presented in an accessible way for researchers, engineers, developers, and practitioners from academia and industry working in all major areas and interdisciplinary areas of hybrid computational intelligence and communication systems to evolve human-centered modeling and simulations of real-time data-intensive intelligent systems.

Book Internet of Things Based Machine Learning in Healthcare

Download or read book Internet of Things Based Machine Learning in Healthcare written by Prasenjit Dey and published by CRC Press. This book was released on 2024-06-10 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Internet of Medical Things (IoMT) is a system that collects data from patients with the help of different sensory inputs, e.g., an accelerometer, electrocardiography, and electroencephalography. This text presents both theoretical and practical concepts related to the application of machine learning and Internet of Things (IoT) algorithms in analyzing data generated through healthcare systems. Illustrates the latest technologies in the healthcare domain and the Internet of Things infrastructure for storing smart electronic health records Focuses on the importance of machine learning algorithms and the significance of Internet of Things infrastructure for healthcare systems Showcases the application of fog computing architecture and edge computing in novel aspects of modern healthcare services Discusses unsupervised genetic algorithm-based automatic heart disease prediction Covers Internet of Things–based hardware mechanisms and machine learning algorithms to predict the stress level of patients The text is primarily written for graduate students and academic researchers in the fields of computer science and engineering, biomedical engineering, electrical engineering, and information technology.

Book A Guide to Applied Machine Learning for Biologists

Download or read book A Guide to Applied Machine Learning for Biologists written by Mohammad "Sufian" Badar and published by Springer Nature. This book was released on 2023-06-21 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is an introductory guide to applied machine learning, specifically for biology students. It familiarizes biology students with the basics of modern computer science and mathematics and emphasizes the real-world applications of these subjects. The chapters give an overview of computer systems and programming languages to establish a basic understanding of the important concepts in computer systems. Readers are introduced to machine learning and artificial intelligence in the field of bioinformatics, connecting these applications to systems biology, biological data analysis and predictions, and healthcare diagnosis and treatment. This book offers a necessary foundation for more advanced computer-based technologies used in biology, employing case studies, real-world issues, and various examples to guide the reader from the basic prerequisites to machine learning and its applications.

Book Handbook of Research on Machine Learning

Download or read book Handbook of Research on Machine Learning written by Monika Mangla and published by CRC Press. This book was released on 2022-08-04 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume takes the reader on a technological voyage of machine learning advancements, highlighting the systematic changes in algorithms, challenges, and constraints. The technological advancements in the ML arena have transformed and revolutionized several fields, including transportation, agriculture, finance, weather monitoring, and others. This book brings together researchers, authors, industrialists, and academicians to cover a vast selection of topics in ML, starting with the rudiments of machine learning approaches and going on to specific applications in healthcare and industrial automation. The book begins with an overview of the ethics, security and privacy issues, future directions, and challenges in machine learning as well as a systematic review of deep learning techniques and provides an understanding of building generative adversarial networks. Chapters explore predictive data analytics for health issues. The book also adds a macro dimension by highlighting the industrial applications of machine learning, such as in the steel industry, for urban information retrieval, in garbage detection, in measuring air pollution, for stock market predictions, for underwater fish detection, as a fake news predictor, and more.

Book Advances in Distributed Computing and Machine Learning

Download or read book Advances in Distributed Computing and Machine Learning written by Suchismita Chinara and published by Springer Nature. This book was released on 2023-06-27 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of peer-reviewed best selected research papers presented at the Fourth International Conference on Advances in Distributed Computing and Machine Learning (ICADCML 2023), organized by Department of Computer Science and Engineering, National Institute of Technology, Rourkela, Odisha, India, during 15–16 January 2023. This book presents recent innovations in the field of scalable distributed systems in addition to cutting edge research in the field of Internet of Things (IoT) and blockchain in distributed environments.