Download or read book Handbook of Eicosanoids 1987 written by A. L. Willis and published by CRC Press. This book was released on 2017-11-22 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.

Download or read book CRC Handbook of Eicosanoids Volume II written by A. L. Willis and published by CRC Press. This book was released on 2017-07-28 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.

Download or read book The Eicosanoids written by Peter Curtis-Prior and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).

Download or read book Nutrition Applied to Injury Rehabilitation and Sports Medicine written by Luke R. Bucci and published by CRC Press. This book was released on 2020-10-25 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and exciting new book brings together for the first time the readily available choices of dietary supplements and their relationship to injury rehabilitation. Nutrition Applied to Injury Rehabilitation and Sports Medicine supports the rational use of specific nutrients for specific healing conditions. Guidelines for nutritional programs applied to specific conditions are provided for practical application.

Download or read book Handbook of Platelet Physiology and Pharmacology written by Gundu H.R. Rao and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive work to review blood platelet biochemistry, physiology, pharmacology, and function. It provides up-to-date information on how platelets function, the biochemical mechanisms that modulate their physiology and function, as well as the pharmacology of platelet inhibitory drugs.

Download or read book Omega 3 Fatty Acids and Health written by Joyce A. Nettleton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evidence that omega-3 fatty acids are essential for human development and most helpful to achieve good health throughout life is clearly documented by Dr. Joyce Nettleton in her new book Omega-3 Fatty Acids and Health. Omega 3 fatty acids are produced by the plants of the land and sea. The tissues of the body require the omega-3 fatty acids for their proper functioning just as they also need the omega-6 essential fatty acids. It is probable in man's evolutionary development that there has always been the proper balance between these two groups of essential fatty acids, but in the modern era with the provision of inexpensive vegetable oils it is possible that the pendulum for increased dietary omega-6 fatty acids in the form of linoleic acid has swung too far and the intake ofomega-3 fatty acids has actualIy declined. In particular, the 22 carbon omega 3 fatty acid, docosahexaenoic acid, which has six double bonds, is important in the membranes of brain cells, heart muscle cells, the rods and cones of the retina and spermatozoa. Docosahexaenoic acid is found only in foods such as fish and other sea life, having been synthesized by the phytoplankton of the waters. An outright deficiency of omega-3 fatty acids has led to a number of distur bances in animals and human infants such as impaired vision, abnormalities of the electroretinogram, of the eye and various behavioral aberrations.

Download or read book Handbook of Food Analytical Chemistry Volume 1 written by Ronald E. Wrolstad and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 1397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing effective, state-of-the art methodology and written by recognized experts in the field, the Handbook of Food Analytical Chemistry is an indispensable reference for food scientists and technologists to enable successful analysis. * Provides detailed reports on experimental procedures * Includes sections on background theory and troubleshooting * Emphasizes effective, state-of-the art methodology, written by recognized experts in the field * Includes detailed instructions with annotated advisory comments, key references with annotation, time considerations and anticipated results

Download or read book Profiles of the Nutrients 1 Carbohydrate Lipid and Protein written by Richard Rydon and published by Lulu.com. This book was released on 2016-10-02 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1 of 'Profiles of the Nutrients' by Richard Rydon covers the macronutrients required for energy supply in the body. The topics considered include Water, Oxygen, Energy, Carbohydrate including Fibre, Lipid including the Essential Fatty Acids and Protein including the Essential Amino Acids. In all, the series comprises three books. The second part deals with Minerals and Trace Elements. Finally the third part deals with Water-Soluble and Fat-Soluble Vitamins.

Download or read book Cell Chemistry and Physiology Part I written by Edward Bittar and published by Elsevier. This book was released on 1996-01-04 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a 4-volume module that is an introduction to the study of cell chemistry and physiology. It is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are central to an understanding of cell biology and those that are certain to become of increasing importance in the teaching of modern medicine.We have followed what appeared to as to be the logical divisions of the subject beginning with proteins. Allewell and her colleagues stress the point that proteins fold spontaneously to form complex three-dimensional structures and that some of them unfold with the help of proteins called chaperones. Michaelis-Menten kinetics are shown by Nelsestuen to describe the behaviour of enzymes in the test tube. The formalism is particularly useful in the search for agents of therapeutic value, as exemplified by methotrexate. Uptake by mammalian cells of substrates and their metabolic conversions are discussed by van der Vusse and Reneman. However, both Welch and Savageau expound the view that the cell is not simply a bagful of enzymes. The biologist is urged by Savageau to abandon Michaelis-Menten formalism and apply the Power Law. The biologist is also told that the approach to arriving at a theory of metabolic control would have to be one of successive approximations requiring the use of the computer. Information gained from comparative biochemistry is shown by Storey and Brooks to have shed new light on mechanisms of metabolic rate depression and freeze tolerance, and to be applicable to organ transplantation technology. We are reminded that enzyme adaptation is partly the result of the presence of a hydrating shell of vicinal water that stabilises conformation of the enzyme. Vicinal water, according to Drost-Hausen and Singleton, lies adjacent to most solids and protein interfaces. The kinks or breaks observed in the slope of the Arrhenius plot are attributed to structural changes in vicinal water. Regulation of cell volume is shown by Hempling to involve regulation of cell water. It could be that the osmo-receptor or volume detection system is a protein that links the cytoskeleton to specific K and C1 channels. Additionally, it is interesting that aquaporins, which are water channel-forming membrane proteins, are now known to exist in both renal and extra-renal tissues. One of the renal porins is affected by vasopressin. We then pass on to protein synthesis (Rattan) and other important topics including protein glycosylation (Hounsell), methylation (Clarke), ADP-ribosylation (Pearson) and prenylation (Gelb). Among the four types of lipids attached to membrane proteins are the prenyl groups. Ford and Gross in their chapter on lipobiology drive home the point that there is an accumulation of acyl carnitine and lysophospholipids during myocardial infarction.

Download or read book Bio Assays for Oxidative Stress Status written by W.A. Pryor and published by Elsevier. This book was released on 2012-12-02 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place.Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state.Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified?This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above.

Download or read book Handbook of Obesity Volume 1 written by George A. Bray and published by CRC Press. This book was released on 2014-02-10 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, we've developed a much better grasp of the biological and other factors associated with the development of obesity. Reflecting our evolving understanding of causes and consequences, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology provides comprehensive coverage of the biological, behavioral, and environmental deter

Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1994-02-08 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is devoted solely to the research area of metalloenzymes involving amino acid-residue and related radicals. Topics covered include: general considerations; structure, function and engineering of peroxidases; and ribonucleotide reductase in mammalian systems.

Download or read book Insect Lipids written by David Warren Stanley and published by U of Nebraska Press. This book was released on 1993-01-01 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 1 Principles and Practice of Toxicologic Pathology written by Wanda M. Haschek and published by Academic Press. This book was released on 2021-10-20 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Download or read book CRC Handbook of Eicosanoids Volume II written by A. L. Willis and published by CRC Press. This book was released on 2017-07-28 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.

Download or read book Prostaglandins Leukotrienes and Other Eicosanoids written by Friedrich Marks and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new light on today's most common diseases including atherosclerosis, cancer, Alzheimer's, allergies, and rheumatic diseases. The recent advances already have far-reaching implications in medicine. This detailed account, written by leading experts, covers the ground-breaking developments in recent eicosanoid research. The topics span eicosanoid biogenesis, new aspects of their pathophysiology, for example their influence on the cardiovascular system, as well as the clinical application of synthetic eicosanoids and their antagonists. Researchers and students working in biochemistry or in pharmaceutical, physiological, medicinal and neurochemistry will value this informative introduction to one of the most rapidly developing fields in cell biology.

Download or read book Handbook of Burns Volume 1 written by Marc G. Jeschke and published by Springer Nature. This book was released on 2019-10-29 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides updated information on acute burn treatment. It also discusses genomic responses to burns and novel techniques in this area. Divided into four topical parts, this book provides insights into the history, epidemiology, prevention of burns, as well as initial and pre-hospital management of burns, acute burn care and therapy, and non-thermal burns. All chapters have been edited by leading world authorities on burn care and offer readers a broad overview of the techniques and outcomes in this area. Please also have a look at "Handbook of Burns Volume 2 - Reconstruction and Rehabilitation 2nd edition".