Download or read book Half a Century of Free Radical Chemistry written by Derek H. R. Barton and published by Cambridge University Press. This book was released on 1993-04-15 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the experience over 25 years of the senior author with the chemistry of organic free radicals. It begins with a mechanistic study of industrial importance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. There follows 20 years of practical work to prove the theory correct, especially in the case of morphine alkaloids. The book then describes the work on nitrile photolysis (Barton reaction) which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. There follows a description of the invention of an important new method for the deoxygenation of biologically important molecules, especially sugars and nucleosides, using radical chemistry applied to thiocarbonyl derivatives. Some years later, in a logical extension to carboxylic acids, another new reaction was invented which provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.
Download or read book Reagents for Radical and Radical Ion Chemistry written by David Crich and published by John Wiley & Sons. This book was released on 2013-05-30 with total page 1874 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.
Download or read book From Atoms to Molecules written by Colin A. Russell and published by Taylor & Francis. This book was released on 2024-08-01 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this volume by Professor Russell is the history of organic chemistry, which arose improbably out of early speculations about the construction of chemical compounds, and in particular their electrochemical nature. The rise of electrochemistry and the work of Berzelius were critical in this regard, and receive much attention in the first few chapters in this book. Aspects of the contributions of Frankland (fully explored elsewhere) and those of Kekulê and Hofmann are considered, together with the miscellaneous functions of organic synthesis and the origins of conformational analysis. Questions of chemical organisation are germane to the whole sequence of events and are briefly summarized before the whole last hundred years of organic chemistry are placed in historical perspective.
Download or read book Organosilanes in Radical Chemistry written by Chryssostomos Chatgilialoglu and published by John Wiley & Sons. This book was released on 2004-04-02 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years silicon-centered radicals have played an important role in organic synthesis, polymer chemistry and material sciences. The aim of this book is to offer for the first time a description of silyl radicals within an interdisciplinary context, connecting structural characteristics and chemical properties to their application in different areas of chemistry. The first time different aspects of silyl radicals have been brought together Excellent reference tool for experienced practitioners of radical and/or silicon chemistry Presents various aspects of these intermediates in an original, comprehensive fashion This book is essential for anyone working in free radical and/or silicon chemistry as well as for those who want to approach these fields for the first time.
Download or read book Streamlining Free Radical Green Chemistry written by V. Tamara Perchyonok and published by Royal Society of Chemistry. This book was released on 2012 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, concise guide showcases the sustainable methods offered by green free radical chemistry and summarizes the fundamental science involved.
Download or read book CRC Handbook of Organic Photochemistry and Photobiology Volumes 1 2 written by William M. Horspool and published by CRC Press. This book was released on 2003-09-29 with total page 2898 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this best-selling handbook is bigger, more comprehensive, and now completely current. In addition to thorough updates to the discussions featured in the first edition, this edition includes 66 new chapters that reflect recent developments, new applications, and emerging areas of interest. Within the handbook's 145 critically r
Download or read book Chemical History written by Gerrylyn K Roberts and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an historical overview of the recent developments in the history of diverse fields within chemistry. It follows on from Recent Developments in the History of Chemistry, a volume published in 1985. Covering chiefly the last 20 years, the primary aim of Chemical History: Reviews of the Recent Literature is to familiarise newcomers to the history of chemistry with some of the more important developments in the field. Starting with a general introduction and look at the early history of chemistry, subsequent chapters go on to investigate the traditional areas of chemistry (physical, organic, inorganic) alongside analytical chemistry, physical organic chemistry, medical chemistry and biochemistry, and instruments and apparatus. Topics such as industrial chemistry and chemistry in national contexts, whilst not featuring as separate chapters, are woven throughout the content. Each chapter is written by experts and is extensively referenced to the international chemical literature. Chemical History: Reviews of the Recent Literature is also ideal for chemists who wish to become familiar with historical aspects of their work. In addition, it will appeal to a wider audience interested in the history of chemistry, as it draws together historical materials that are widely scattered throughout the chemical literature.
Download or read book Copper Oxygen Chemistry written by Kenneth D. Karlin and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the vastly expanding subject of oxidative processes mediated by copper ions within biological systems Copper-mediated biological oxidations offer a broad range of fundamentally important and potentially practical chemical processes that cross many chemical and pharmaceutical disciplines. This newest volume in the Wiley Series on Reactive Intermediates in Chemistry and Biology is divided into three logical areas within the topic of copper/oxygen chemistry— biological systems, theory, and bioinorganic models and applications—to explore the biosphere for its highly evolved and thus efficient oxidative transformations in the discovery of new types of interactions between molecular oxygen and copper ion. Featuring a diverse collection of subject matter unified in one complete and comprehensive resource, Copper-Oxygen Chemistry probes the fundamental aspects of copper coordination chemistry, synthetic organic chemistry, and biological chemistry to reveal both the biological and chemical aspects driving the current exciting research efforts behind copper-oxygen chemistry. In addition, Copper-Oxygen Chemistry: Addresses the significantly increasing literature on oxygen-atom insertion and carbon-carbon bond-forming reactions as well as enantioselective oxidation chemistries Progresses from biological systems to spectroscopy and theory, and onward to bioinorganic models and applications Covers a wide array of reaction types such as insertion and dehydrogenation reactions that utilize the cheap, abundant, and energy-containing O2 molecule With thorough coverage by prominent authors and researchers shaping innovations in this growing field, this valuable reference is essential reading for bioinorganic chemists, as well as organic, synthetic, and pharmaceutical chemists in academia and industry.
Download or read book Amines written by Stephen A. Lawrence and published by Cambridge University Press. This book was released on 2004-09-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of amine chemistry is of paramount importance to numerous chemical industries, as well as academic research. This book provides an authoritative account of the properties and applications of amines with respect to the characteristics of bonded substituents and the nature of their surrounding chemical and physical environments. The synthesis of alkyl, aryl and heterocyclic amines and inorganic amines with a review of their typical reactions is comprehensively treated, whilst practical synthetic and analytical methods for laboratory preparation and detection are provided. The importance of amine chemistry from the nineteenth century to the modern day, with a brief history of the development of ammonia synthesis, is included.
Download or read book The Bartonian Legacy written by Pierre Potier and published by World Scientific. This book was released on 2000-12-18 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bartonian Legacy is a collection of memoirs, reminiscences and biographical details regarding Sir Derek Barton (1918-1998) who was one of the most influential organic chemists of the 20th Century. The chapters are contributed by some of his many students, coworkers and scientific colleagues, all of whom testify to his fascinating character and true genius. It offers intimate glimpses at Sir Derek's scientific life, his sense of humor and his modus operandi as a teacher of research methods. The volume will serve as a valuable companion work to the more official biographies and obituaries, several of which have already been published./a
Download or read book Advances in Pharmacology written by and published by Academic Press. This book was released on 1996-12-02 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.
Download or read book Reason and Imagination written by Sir Derek Barton and published by World Scientific. This book was released on 1996 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the recognition of new principles in Organic Chemistry. It is also about the discovery and invention of Chemical Reactions. In addition, it deals with the determination of structure by chemical degradation during the epoch when physical methods were not well developed. Also presented are new reagents and new types of functional groups never seen in chemistry before. The overall aim of the collected papers is to show how thought can direct original research and to demonstrate how thought about old or new chemical facts can lead to originality. This is further illuminated by commentaries which Prof Barton has written to accompany these papers.
Download or read book Oxidation and Antioxidants in Organic Chemistry and Biology written by Evgeny T. Denisov and published by CRC Press. This book was released on 2005-03-29 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive review of reactions of oxidation for different classes of organic compounds and polymers, and biological processes mediated by free radicals, Oxidation and Antioxidants in Organic Chemistry and Biology puts the data and bibliographical information you need into one easy-to-use resource. You will find up-to-date information
Download or read book Redox Signaling and Biomarkers in Ageing written by Ufuk Çakatay and published by Springer Nature. This book was released on 2021-12-02 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach. Establishing sensitive and specific biomarkers of dynamic redox homeostasis is crucially important in the development of effective antiaging and senolytic interventions. Recent years have seen tremendous advances in the understanding of redox signaling events which highlight the process of aging and age-related pathologies. A major challenge in biological aging research is developing reliable biomarkers to determine the consequences of disrupted redox signaling networks long before the clinical diagnosis of age-related diseases is made. Therefore, we have chosen to concentrate on aging-induced aberrant redox signaling networks, their biomarkers, and pathological consequences in this book. Although oxidation is a natural metabolic process, the imbalance in the level of oxidants and antioxidants causes oxidative stress and eventually leads to inflammatory conditions, diabetes, neurodegenerative diseases, and cancer. Novel redox-sensitive biomarkers for the evaluation of aging-induced proteinopathies such as amyloid ß and tau proteins in Alzheimer's disease, α-synuclein in Parkinson's disease, and islet amyloid polypeptides in type 2 diabetes mellitus recently drew the attention of researchers. Inside this textbook, readers will find comprehensive perspectives on the association between redox homeostasis and the aging process both at the molecular and clinical levels. Due to the inherent relationship between impaired metabolic activities and oxidative stress, the temporal interaction between intermediary metabolism and disturbed redox status can lead to greater susceptibility to aging-induced diseases and disorders, such as cardiovascular diseases, hypertension, and diabetes. This knowledge could be a key to continued research toward improving medication regimens such as in cancer and cardiovascular therapies, and procedural outcomes for patients. This book brings together current research evidence and knowledge on redox signaling and biomarkers in aging in chapters written by leading global experts in this rapidly evolving field. We hope that this textbook is of interest to a wide group of researchers, advanced students, scientifically curious non-specialist readers and clinicians alike.
Download or read book Organic Photochemistry written by James Morriss Coxon and published by Cambridge University Press. This book was released on 1987-04-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the decade after this book first appeared in 1974, research involving organic photochemistry was prolific. In this updated and expanded 1986 edition the authors summarise those classes of reaction that best illustrate the types of photochemical behaviour commonly observed for simple organic molecules. The different products obtained from compounds subjected to thermal and photolytic activation are explained with the aid of appropriate diagrams and mechanistic schemes. Where necessary, these are backed up by simple energy level profiles. Thus, theory and empirical data are interwoven to provide a firm basis which is aided by the generous basic references at the end of each chapter.
Download or read book Sulfur Centered Reactive Intermediates in Chemistry and Biology written by C. Chatgilialoglu and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: A wonderfully successful NATO Advanced Study Institute on "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" was held 18-30 June, 1989, at the Hotel Villa del Mare in Maratea, Italy. Despite the beautiful setting with mountains behind us and over looking the clear blue Mediterranean Sea under a cloudless sky (and with a private beach available), the lectures were extremely well attended. While some credit can go to the seriousness of the students, more must go to the calibre of speakers and the high quality of C. Chatgilialoglu, and Co-Director, Professor K. -D. their presentations. The Director, Dr. Asmus, are to be congratulated for putting together such an outstanding scientific program. Dr. Chatgilialoglu is also to be commended for arranging an equally stimulating social pro gram which included bus, train and boat trips to many local sites of interest. It was particularly fitting that a meeting on the chemistry and biochemistry of sulfur should be held in Italy since Italian chemists have made major contributions to our under standing of the organic chemistry of sulfur, including the chemistry of its reactive inter mediates. The early Italian interest in sulfur chemistry arose from the fact that Italy, or more specifically, Sicily, was a major world producer of sulfur prior to the development and exploitation of the Frasch process in Texas and Louisiana.
Download or read book The Formation and Stabilization of Free Radicals written by United States. National Bureau of Standards and published by . This book was released on 1957 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
