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Book HADI COMPREHENSIVE NEONATAL MEDICATIONS

Download or read book HADI COMPREHENSIVE NEONATAL MEDICATIONS written by DR.ABDELHADI ABDELGABBAR ABDELHADI and published by ABDELHADI ABDELGABBAR ABDELHADI. This book was released on 2024-01-24 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is intended to provide comprehensive yet concise information on indications, doses, preparation, administration, and adverse reactions of drugs in use during the neonatal period. There is particular emphasis on preparation and administration by neonatal nurses. Compatibility of intravenous medications with concurrent other fluids or medications are thoroughly addressed. The routes for the administration of various medications are delineated. The most recognised adverse effects of various medications are flagged up, but the lists are by no means all-inclusive. It is advisable to consult up to date periodically if reactions or side effects outside the specific monograph texts are encountered. Furthermore, the publication focuses on known contraindications, precautions, and practical advice. A considerable effort has been exercised to ensure the doses, calculations, with or without dilutions, are accurate. However, further confirmation by the nursing and medical personnel is advised prior to the first use of each individual monograph. Feedback and suggestions are appreciated and can be sent to [email protected]. It is acknowledged that many neonatal units prefer to custom their own dilutions, concentrations, and infusion times. Nevertheless, the information in the various monographs is counterchecked with the practice of various well recognised international neonatal units. The use of computerised programmed infusion pumps is ideal but is not available in most nurseries. The latest edition of the British National Formulary for Children (BNFc, September 2022-September 2023, Last updated 14 December 2022) is used as the primary source for many medications' doses, side effects and contraindications. Various other useful references are utilised and are listed on the last page. The intention is to update the information on the web version of this publication on a regular basis. The publication is written bearing in mind the wide variations in the skill mix of neonatal practitioners, both nurses and doctors. Likewise, the challenging circumstances in developing countries are taken into consideration. Many of the stated calculations, methods of infusions or administration and monitoring requirements may appear too extensive and long winded. However, this is intended to be excessively simple to take some pressure off the shoulders of busy doctors and nurses. Printing and laminating individual monographs for the commonly used medications extracted from this publication is highly recommended. It would provide a quick and easily accessible source when every minute counts. The publication reflects the author's own acceptable and safe practices and advice. It is written with the intention of facilitating the delivery of care to the most vulnerable newborn. However, the responsibility of correct prescriptions, calculations and administration falls on the individual practitioners. The clinical pharmacist of the hospital may be requested to endorse individual drug monographs or the whole publication before the neonatal unit adopts it. It is a legal requirement to advise users of the information provided within this publication that the editor and publisher are not responsible for any errors or omissions and/or any consequences arising from the use of the information in this book.

Book HADI PRACTICAL NEONATOLOGY BOOK 1

    Book Details:
  • Author : ABDELHADI ABDELGABBAR ABDELHADI
  • Publisher : DR ABDELHADI ABDELGABBAR ABDELHADI MBBS, MRCP, FRCPCH
  • Release : 2024-01-24
  • ISBN :
  • Pages : 444 pages

Download or read book HADI PRACTICAL NEONATOLOGY BOOK 1 written by ABDELHADI ABDELGABBAR ABDELHADI and published by DR ABDELHADI ABDELGABBAR ABDELHADI MBBS, MRCP, FRCPCH. This book was released on 2024-01-24 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hadi Practical Neonatology ,a 2-book series of practical guidelines, is intended to provide a structured approach to the management of neonatal conditions which are likely to face the neonatal team. It is not intended to replace textbooks or to teach the beginners in the field. Prior sound knowledge of Neonatal Medicine, by the user, is essential. This book is the first in the series. It covers aspects of RESUSCITATION, THERMAL CONTROL- RESPIRATORY-CARDIOVASCULAR-INFECTIONS- ENDOCRINE & METABOLIC-GASTROINTESTINAL & NUTRITION- DERMATOLOGY- and SURGICAL NEWBORN challenges. It is my belief that neonatal doctors and nurses are an integrated team, and any demarcation is an imaginary line. The recipe of creating a backbone of good nurses is passionate support, continuous education, and practical teaching at every possible opportunity. Mutual trust and appropriate delegations are crucial to the success of the team. HADI PN series is written for the neonatal team and not just for the medical staff. The best way for consolidating the team knowledge and experience is bedside teaching. New methods and approaches of neonatal management are progressing but seem to slow down over the last few years. This may reflect the fact neonatal advances are approaching our era peak of “what is possible.” Nevertheless, many of our current practices are yet to be scrutinized to fulfil the evidence-based standards. There is no robust verification of the evidence behind our current practice of many routine day to day applications. This include but not limited to fluid requirements, duration of antibiotics courses, use of various blood products, seizures pharmacological treatment, and safe PaCO2 levels. I have reviewed multiple medical and nursing guidelines from Europe, North America, and Australia as well as Asia, South America, and Africa. I integrated many of these guidelines within this book whenever they are in accord with the international acceptable practices. Feedback and suggestions are welcome and can be sent to [email protected] The book is an updated version of the protocols and guidelines which I have developed during my work as Consultant Neonatologist. Some are adopted from various reputable institutes and modified to reflect the current evidence plus a slight flavour of my experience. Considerable effort has been exercised to ensure the doses of medications given in HADI PN are accurate. However, further confirmation by the nursing and medical staff is advised prior to the first use of each medication. HADI PN reflects the author’s own acceptable and safe practice and advice. It is written with the intention of facilitating the delivery of care to the most vulnerable newborn. The publication is written bearing in mind the wide variations in the skill mix of neonatal practitioners, nurses, and doctors. Likewise, the chall

Book NEW TO NICU

    Book Details:
  • Author :
  • Publisher : ABDELHADI ABDELGABBAR ABDELHADI
  • Release : 2024-05-16
  • ISBN :
  • Pages : 196 pages

Download or read book NEW TO NICU written by and published by ABDELHADI ABDELGABBAR ABDELHADI. This book was released on 2024-05-16 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: The experience of walking into the neonatal unit for the first time is frightening to parents, doctors, and nurses. The beautiful decorations, elegant furniture and the gracefully dimmed lights are not seen, as if they are not existing. What matters for parents is their baby, and they see nothing but their baby. For new nurses and doctors, the tension and stress of the unfamiliar environment pulls a cataract-like blinds across both eyes. Then comes the next challenge: the Jargon and unique phrases in common use in NICU. The team, in every neonatal unit, has adopted hundreds of peculiar and unfamiliar terms as part of their daily language. They always make some efforts to explain themselves, only to divert back to their tested and trusted language. I, like many other colleagues, have struggled on many occasions to keep away from the medical jargon while talking to parents or relatives. There are countless references, books and internet sites which give tables of NICU abbreviations and terms and their counter words or phrases. This book is not intended to add to these useful resources, as they are far from perfect. The mere provision or listing of the abbreviations and their meanings, does not provide the parents or beginners with the backbone of knowledge, upon which they could assimilate in depth exploration of the challenge in question. On the other hand, there is plethora of neonatal conditions which make thorough explanation of each and everyone of them, an impossible and daunting task. Any book, in that scenario, will be comprehensive but not practical due to its length. This book, (NEW TO NICU), tries to introduce NICU to all newcomers: parents, nurses, and doctors. It highlights the essential structure of NICU and how to approach it by those who are new to it. It introduces NICU family with a brief description of their roles. Then the book goes in detail to explore the majority of day-to-day NICU language. This is coupled with summary to the situations behind phrases or abbreviations. There are some areas where the explanations are intentionally detailed, while in other areas, a brief description is offered. The communication with the neonatal team is irreplaceable and face to face discussions are the gold standard of successful dialogues. The information about the baby condition, current status, medications, nutrition, and growth are normally conveyed by the nursing staff. The questions about why (Causation), what (Condition), when (Anticipation) and how the future looks for the baby (Prognosis), are best discussed with the Doctors. Consistent and factual information build the trust between parents and the managing team. There is a place for emotions in all the interactions between staff and parents, but emotions should not colour facts to deal with the short-term outcome or long-term prognosis. New nurses and doctors joining NICU find themselves out of their depth in the first few days-weeks. This is not related to their inexperience or ignorance, but only because they are not able to follow conversations riddled with mines of abbreviations in every single sentence. I remember vividly in my first job in UK, when a nurse phoned me to tell a baby’s cannula is tissued. I felt very embarrassed (Being an experienced Registrar coming from overseas), that I could not even ask for the meaning of this phrase. I replied by saying “Thank You,” to which she replied: “Are you coming now?” I put the phone down after I said Yes!! I immediately rang my sister who is a radiologist in London, who was even more surprised that I did not know the meaning of “Cannula is tissued.” This is just one example of many which may look trivial but the accumulation of these gaps in conversations are difficult to live with. Ward rounds in particular are stressful times for those who are not familiar with NICU jargon. The jargon and abbreviations infiltrate every aspect of communication in NICU: Handovers, day to day care, resuscitation, non-emergency procedures and even offering the baby breast milk obtained from the mother! The use of abbreviations is unacceptable to many people but is the bear reality in each hospital department, and NICU is not an exception. The staff are advised to use the approved abbreviations which are published by each hospital governance body. The use of non approved abbreviations may lead to dire clinical and legal consequences. Furthermore, the staff should make every possible effort to explain to parents, in simple language, what is meant by an abbreviation or a commonly used phrase. I hope this book helps newcomers to NICU including parents, nurses, and doctors.

Book Comprehensive Neonatal Nursing Care

Download or read book Comprehensive Neonatal Nursing Care written by Carole Kenner and published by Springer Publishing Company. This book was released on 2013-08-21 with total page 1023 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart

Book Physical Assessment of the Newborn

Download or read book Physical Assessment of the Newborn written by Ellen P. Tappero, DNP, RN, NNP-BC and published by Springer Publishing Company. This book was released on 2014-09-01 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Assessment of the Newborn, 5th Edition, is a comprehensive text with a wealth of detailed information on the assessment of the newborn. This valuable and essential resource illustrates the principles and skills needed to gather assessment data systematically and accurately, and also provides a knowledge base for interpretation of this data. Coverage addresses: gestational assessment, neurologic assessment, neonatal history, assessment of the dysmorphic infant, and systemic evaluation of individual body systems, as well as key information on behavioral and pain assessment, including the use of specific tools with various groups ranging from term to extremely preterm infants. Numerous tables, figures, illustrations, and photos, many of them in full color, are a major strength that enhances the book’s usefulness as a clinical resource. The text is an excellent teaching tool and resource for anyone who performs newborn examinations including nurses, neonatal and pediatric nurse practitioners, nurse-midwives, physicians and therapists. It can also serve as a core text for any program preparing individuals for advanced practice roles in neonatal care. KEY FEATURES: An authoritative and renowned text that comprehensively addresses all key aspects of newborn assessment Provides a well-ordered evaluation of individual body systems. Assists the practitioner in identifying infant state, behavioral clues, and signs of pain, facilitating individualized care. Comprehensively addresses the tremendous range of variation among newborns of different gestational ages. The content is amplified by numerous photos and illustrations, many in full color Includes Power Point slides and an Image Bank

Book HADI PRACTICAL NEONATOLOGY BOOK 2

    Book Details:
  • Author : DR.ABDELHADI ABDELGABBAR ABDELHADI MBBS,MRCP,FRCPCH
  • Publisher : ABDELHADI ABDELGABBAR ABDELHADI
  • Release : 2024-01-24
  • ISBN :
  • Pages : 412 pages

Download or read book HADI PRACTICAL NEONATOLOGY BOOK 2 written by DR.ABDELHADI ABDELGABBAR ABDELHADI MBBS,MRCP,FRCPCH and published by ABDELHADI ABDELGABBAR ABDELHADI. This book was released on 2024-01-24 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hadi Practical Neonatology (Hadi PN), a 2-book series of practical guidelines, is intended to provide a structured approach to the management of neonatal conditions which are likely to face the neonatal team. It is not intended to replace neonatal textbooks or to teach the beginners in the field. Prior sound knowledge of Neonatal Medicine, by the user, is essential. This book is the second in the series. It covers aspects of NEUROLOGY-FLUIDS & ELECTROLYTES, VASCULAR ACCESS & SAMPLING, FREQUENT CHALLENGES , HAEMATOLOGY, JAUNDICE and ESSENTIAL PROCEDURES&PRACTICES challenges. It is my belief that neonatal doctors and nurses are an integrated team, and any demarcation is an imaginary line. The recipe of creating a backbone of good nurses is passionate support, continuous education, and practical teaching at every possible opportunity. Mutual trust and appropriate delegations are crucial to the success of the team. HADI PN series is written for the neonatal team and not just for the medical staff. The best way for consolidating the team knowledge and experience is bedside teaching. New methods and approaches of neonatal management are progressing but seem to slow down over the last 2-3 years. This may reflect the fact neonatal advances are approaching our era peak of “what is possible.” Nevertheless, many of our current practices are yet to be scrutinized to fulfil the evidence-based pathways and standards. There is no robust verification of our current practice of many routine day to day applications. This include but not limited to fluid requirements, duration of antibiotics courses, use of various blood products, and seizures pharmacological treatment. I have reviewed multiple neonatal medical and nursing guidelines from Europe, North America, and Australia as well as guidelines from Asia, South America, and Africa. I integrated many aspects from these guidelines within this text whenever they are in accord with the international acceptable practices. Feedback and suggestions are welcome and can be sent to [email protected] The book is an updated version of the protocols and guidelines which I have developed during my work as Consultant Neonatologist. Many are adopted from various reputable institutes and modified to reflect the current evidence plus a slight flavour of my experience. Considerable effort has been exercised to ensure the doses of medications given in HADI PN are accurate. However, further confirmation by the nursing and medical staff is advised prior to the first use of each medication. HADI PN reflects the author’s own acceptable and safe practice and advice. It is written with the intention of facilitating the delivery of care to the most vulnerable newborn. The publication is written bearing in mind the wide variations in the skill mix of neonatal practitioners, nurses, and doctors. Likewise, the challenging circumstances in developing countries are taken into consideration. It is a legal requirement to advise users of the information provided within this publication that the editor and publisher are not responsible for any errors or omissions and or any consequences arising from the use of this book.

Book Registries for Evaluating Patient Outcomes

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Book Cancer Incidence and Survival Among Children and Adolescents

Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Maternity  Newborn  and Women s Health Nursing

Download or read book Maternity Newborn and Women s Health Nursing written by Susan A. Orshan and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 1186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book will be a core text for undergraduate Maternity/Newborn courses. It also will work for courses emphasizing Women's Health across the lifespan. Coverage includes core content on preconception, pregnancy, labor, birth, and postpartum. In addition, the text focuses on important topics throughout a woman's life: health promotion, nutrition, medical issues, psychosocial issues, sexuality, family, fertility control and issues, menopause, and aging. While other texts touch on the different stages of a woman's lifespan, this book provides more detail and information in areas outside the average maternity text.

Book Preterm Birth

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2007-05-23
  • ISBN : 030910159X
  • Pages : 791 pages

Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.

Book Essentials of Pediatric Surgery

Download or read book Essentials of Pediatric Surgery written by Sultan Mohsen Ghanem and published by Bentham Science Publishers. This book was released on 2021-11-02 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Pediatric Surgery is an introductory reference on basic pediatric medicine and surgery. The book provides the reader the information on which a surgeon relies on in diagnosis and treatment. Chapters start with the physiology of infants before progressing into separate topics about the surgery of different sections including the head and neck, chest, abdomen, reproductive organs, cancers, and the nervous system. Information is presented in a simple manner, which makes the text easy to understand for both students and medical residents. Key Features: - 8 chapters covering introductory topics about pediatric physiology and surgery - Includes chapters which cover specialized domains in the subject based on different parts of the body - Chapters include information about clinical presentations, diagnosis and treatment of different conditions - Simple, structured layout for easy understanding - References for further reading Essentials of Pediatric Surgery is a handy textbook for both medical students studying modules on pediatric surgery and residents in training in pediatric clinics.

Book How Tobacco Smoke Causes Disease

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Book The Changing Role of the Hospital in European Health Systems

Download or read book The Changing Role of the Hospital in European Health Systems written by Martin McKee and published by Cambridge University Press. This book was released on 2020-08-13 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: A team of world-leading policy experts and clinicians analyse the changing role of the hospital across Europe.

Book Vibrant and Healthy Kids

    Book Details:
  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release : 2019-12-27
  • ISBN : 0309493382
  • Pages : 621 pages

Download or read book Vibrant and Healthy Kids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-27 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.

Book Joints and Connective Tissues

Download or read book Joints and Connective Tissues written by Kerryn Phelps and published by Elsevier Health Sciences. This book was released on 2012-10-31 with total page 1281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Joints and Connective Tissues - General Practice: The Integrative Approach Series. In order to diagnose and manage the patient presenting with musculoskeletal symptoms, it is important to distinguish whether the pathology is arising primarily in the so-called hard tissues (such as bone) or the soft tissues (such as cartilage, disc, synovium, capsule, muscle, tendon, tendon sheath). It is also important to distinguish between the two most common causes of musculoskeletal symptoms, namely inflammatory and degenerative.

Book Alternative Proteins

Download or read book Alternative Proteins written by Alaa El-Din A. Bekhit and published by CRC Press. This book was released on 2022-01-20 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, there has been substantial research dedicated towards prospecting physiochemical, nutritional and health properties of novel protein sources. In addition to being driven by predictions of increased population and lack of a parallel increase in traditional protein sources, main drivers for the rise in novel proteins/ novel foods research activities is linked to significant changes in young consumers’ attitudes toward red meat consumption and their interest in new alternative protein products. Alternative Proteins: Safety and Food Security Considerations presents up-to-date information on alternative proteins from non-meat sources and examines their nutritional and functional roles as food sources and ingredients. Emphasis is placed on the safety of these novel proteins and an evaluation of their potential contribution to food security. Motivations for novel proteins and restrictions for their use are also discussed. Key Features: Explains potential improvements to alternative proteins through the employment of novel processing techniques. Contains the first review on keratin as an alternative protein source. Explores first comprehensive evaluation of the religious aspects of novel proteins. Describes methods for the detection and evaluation of health hazards. Discusses guidelines, regulatory issues and recommendations for food safety Additionally, this book covers fundamental and recent developments in the production of alternative proteins, and examines safety and consumer acceptability wherever information is available. The sources and processing options for alternative proteins and their impact on final product characteristics are also covered. A collective contribution from international researchers who are active in their field of research and have made significant contributions to the the food sciences, this book is beneficial to any researcher interested in the the food science and safety of alternative proteins.

Book Innovations for Next Generation Antibody Drug Conjugates

Download or read book Innovations for Next Generation Antibody Drug Conjugates written by Marc Damelin and published by Springer. This book was released on 2018-05-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.