Download or read book Guidelines for the Clinical Evaluation of Antineoplastic Drugs written by and published by . This book was released on 1981 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Clinical Evaluation of Antineoplastic Drugs written by and published by . This book was released on 1981 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Clinical Evaluation of Antineoplastic Drugs written by and published by . This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anticancer Drug Development Guide written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements for FDA approval. A companion volume by the same editor (Cancer Therapeutics: Experimental and Clinical Agents) reviews existing anticancer drugs and potential anticancer therapies. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field.
Download or read book Clinical Guidelines for the Use of Antineoplastic Agents written by and published by . This book was released on 1982 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Economic Evaluation of Cancer Drugs written by Iftekhar Khan and published by CRC Press. This book was released on 2019-06-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems. With advances in the diagnosis and treatment, more people are diagnosed early and receive treatments for a disease where few treatments options were previously available. As a result, the survival of patients with cancer has steadily improved and, in most cases, patients who are not cured may receive multiple lines of treatment, often with financial consequences for the patients, insurers and healthcare systems. Although many books exist that address economic evaluation, Economic Evaluation of Cancer Drugs using Clinical Trial and Real World Data is the first unified text that specifically addresses the economic evaluation of cancer drugs. The authors discuss how to perform cost-effectiveness analyses while emphasising the strategic importance of designing cost-effectiveness into cancer trials and building robust economic evaluation models that have a higher chance of reimbursement if truly cost-effective. They cover the use of real-world data using cancer registries and discuss how such data can support or complement clinical trials with limited follow up. Lessons learned from failed reimbursement attempts, factors predictive of successful reimbursement and the different payer requirements across major countries including US, Australia, Canada, UK, Germany, France and Italy are also discussed. The book includes many detailed practical examples, case studies and thought-provoking exercises for use in classroom and seminar discussions. Iftekhar Khan is a medical statistician and health economist and a lead statistician at Oxford Unviersity’s Center for Statistics in Medicine. Professor Khan is also a Senior Research Fellow in Health Economics at University of Warwick and is a Senior Statistical Assessor within the Licensing Division of the UK Medicine and Health Regulation Agency. Ralph Crott is a former professor in Pharmacoeconomics at the University of Montreal in Quebec, Canada and former head of the EORTC Health Economics Unit and former senior health economist at the Belgian HTA organization. Zahid Bashir has over twelve years experience working in the pharmaceutical industry in medical affairs and oncology drug development where he is involved in the design and execution of oncology clinical trials and development of reimbursement dossiers for HTA submission.
Download or read book Guidelines for the Clinical Evaluation of General Anesthetics written by and published by . This book was released on 1982 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Safe Handling of Hazardous Drugs written by Martha Polovich and published by . This book was released on 2017-11 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Bureau of Drugs and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Clinical Evaluation of Radiopharmaceutical Drugs written by United States. Food and Drug Administration. Division of Oncology and Radiopharmaceutical Drug Products and published by . This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Guidelines for the Use of Antineoplastic Agents written by Anne D. De Fraine and published by . This book was released on 1990 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Third edition of a handbook describing the practical and clinical uses of cytotoxic drugs in oncology, autoimmune diseases and transplants. The editors have a background in pharmacy and have been assisted by some leading Sydney cancer specialists.
Download or read book Chemotherapy and Biotherapy Guidelines and Recommendations for Practice written by Martha Polovich and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Order your copy of the fourth edition of the best-selling resource used by more than 101,000 healthcare professionals since 2009 and keep up-to-date on the latest chemotherapy, biotherapy, and targeted agents. This new edition of the Chemotherapy and Biotherapy Guidelines and Recommendations for Practice has been revised and updated to reflect the current procedures and practices in your specialty. You'll find that this latest edition incorporates a number of significant changes. To help you find the content and information that you need quickly and easily, the text has been reorganized and is now divided into 11 chapters ranging from an overview of cancer and cancer treatment and principles of antineoplastic therapy to post-treatment care and competencies in chemotherapy administration. Patient education information has also been expanded in the new edition to emphasize importance of education in patient care. And, finally, look for new information on chemotherapy sequencing and updates on the nursing management of treatment side effects.As with previous editions, the guidelines strives to bring you the latest details on approved drugs, standards of practice, and available evidence. Make sure to update your library with this latest edition of one of the most trusted and widely used resources for practicing oncology nurses.
Download or read book Improving Healthcare Quality in Europe Characteristics Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.
Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Download or read book The Prevention and Treatment of Missing Data in Clinical Trials written by National Research Council and published by National Academies Press. This book was released on 2010-12-21 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Extravasation of Cytotoxic Agents written by Ines Mader and published by Springer Science & Business Media. This book was released on 2003 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Extravasation of cytotoxic drugs can lead to serious complications during tumour therapy. This volume is intended as an aid to assess the situation quickly and conclusively should this emergency occur. The substance specific section of the book provides detailed instructions for how to deal with 49 cytotoxic agents so that targeted measures can be started at once. The general section provides comprehensive information on prevention, general measures to be taken in case of extravasation, specific antidotes, and documentation. For support during everyday clinical practice, the book is accompanied by a template for an extravasation kit, tables, documentation sheets, and patient information." "The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic. The practical instructions are accompanied by a review of the literature to enable readers to study source materials via the original published studies."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
