Download or read book Guide to Receptors and Channels GRAC written by S. P. H. Alexander and published by . This book was released on 2008 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guide to Receptors and Channels GRAC written by and published by . This book was released on 2009 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Concise Guide to Pharmacology 2013 14 written by Stephen P. H. Alexander and published by . This book was released on 2013 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
Download or read book Guide to Receptors and Channels written by Stephen P. H. Alexander and published by . This book was released on 2006 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guide to Receptors and Channels written by S. P. H. Alexander and published by . This book was released on 2004 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guide to Receptors and Channels 1st Edition written by Steve P. H. Alexander and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Concise Guide to Pharmacology 2015 16 written by Stephen P. H. Alexander and published by . This book was released on 2015 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
Download or read book Receptor Biology written by Michael S. Roberts and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses verständlich geschriebene Lehrbuch ist nicht nur hoch informativ, sondern macht die komplexe Thematik der Signalwege von Rezeptoren leichter greifbar. Es eignet sich perfekt für Kurse zu diesem Fachgebiet in den Studiengängen Biologie, Medizin oder Pharmakologie.
Download or read book Rang Dale s Pharmacology written by Humphrey P. Rang and published by Elsevier Health Sciences. This book was released on 2011-04-14 with total page 2651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rang & Dale’s Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Find and cross-reference information quickly using a color-coded layout that makes navigation easy. Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts. Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications. Apply current best practices and clinical applications through thoroughly updated and revised drug information. Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse. Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines.
Download or read book Ion Channels written by James N. C. Kew and published by . This book was released on 2010 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are intimately involved in the everyday physiological functions that enable us to live a full and varied life. When disease strikes, malfunction of ion channels or their dependent is often involved, either as the cause or the effect of the illness. Thus, billions of dollars have been, and still are being, invested in research to understand the physiological and pathophysiological functions of ion channels in an attempt to develop novel therapeutic treatments for a wide range of diseases. This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts. Part one is an introductory overview of the ion channel superfamily and the generic aspects of ion channel function. This part also reviews the methodologies by which ion channel function can be studied from the perspective of performing detailed biophysical characterization through to the deployment of high throughput approaches for identifying novel ion channel ligands. Part two of the book provides an in-depth review of the individual ion channel subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion Channels, and Polymodal-Gated Ion Channels, with each chapter focused on specific family members. These chapters have been written by world leading experts and provide a detailed overview of the structure, biophysics, localization, pharmacology, physiology, and disease relevance of each particular ion channel subfamily. Reviewing both the basic principles of ion channel function and providing a detailed up-to-date review of the phsyiological and pharmacological aspects of individual ion channel sub-families, this book constitutes both an excellent introduction to the field for non-specialists, as well as a highly valuable reference text for experienced researchers already working in the ion channel area.
Download or read book Principles and Practice of Regional Anaesthesia written by Graeme McLeod and published by Oxford University Press. This book was released on 2013 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this highly successful textbook discusses the practical applications of the various methods of regional anaesthesia, including ultrasound, as well as giving an account of their theoretical aspects. The well-established author team use their experience to provide a practical and stimulating book which reflects everyday clinical activity, supplemented by high definition ultrasound images and schematic diagrams. The book will also discuss the place of regional anaesthesia in current medical practice, particularly with regard to pain processes, ultrasound imaging, and patient outcomes. Regional anaesthesia is a rapidly expanding sub-speciality of anaesthesia: routine provision of long-lasting pain relief and the introduction of real-time ultrasound block has fuelled a demand for cadaver and ultrasound-based anatomy training courses. Thus, it is more important than ever to have a thorough grounding in this exciting subspecialty.
Download or read book Mechanically Gated Channels and their Regulation written by Andre Kamkin and published by Springer Science & Business Media. This book was released on 2012-12-05 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. In our opinion the book presents not only the latest achievements in the field but also brings the problem closer to the experts in related medical and biological sciences as well as practicing doctors. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different living organs and tissues and allows to predict changes, which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. We also hope that presenting the problem will attract more attention to it both from researchers and practitioners and will assist to efficiently introduce it into the practical medicine.
Download or read book Membrane Receptors Channels and Transporters in Pulmonary Circulation written by Jason X. -J. Yuan and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets. We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.
Download or read book Transient Receptor Potential Channels written by Md. Shahidul Islam and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 1090 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
Download or read book Basic and Advanced Sciences for Anaesthetic Practice Prepare for the FRCA written by Nicholas Pace and published by Elsevier Health Sciences. This book was released on 2015-11-16 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is one of 10 carefully selected collections of key articles from the Anaesthesia and Intensive Care Medicine journal - a continually updated, evidence-based learning resource, based on the RCOA Curriculum. It is ideal for trainees preparing for the FRCA (or similar) exams. It will also prove an invaluable, authoritative refresher for life-long learning and CPD. Related MCQs are included to test your understanding.
Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Academic Press. This book was released on 2013-01-26 with total page 2033 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. Presents all aspects of biologically active peptides in one resource Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications
Download or read book Transporters as Drug Targets written by Gerhard F. Ecker and published by John Wiley & Sons. This book was released on 2017-04-10 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.
