Download or read book Glycoprotein Hormones written by Joyce W. Lustbader and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the field of glycoprotein hormones necessitated a second international symposium on this topic, held March 11 to 14, 1993, in Santa Barbara, California, and again sponsored by Serono Symposia, USA. The meeting was twofold in its concept: (1) the dissemination of the current research in the field and (2) honoring three scientists who have greatly contributed to this field, Drs. Harold Papkoff, Robert Ryan, and Darrell Ward, upon their retirements. We were honored to have Dr. John Pierre present as a participant at the meeting and also serving as master of ceremonies at the banquet. Certainly one of the highlights at the first meeting, held in 1989, was the cloning of the CG/LH receptor. This second meeting was also filled with insightful and innovative scientific presentations. Significant advances in the regulation of gene transcription of the gonadotropins were presented by Pamela Mellon, James Hoeffler, John Nilson, Bruce Weintraub, and Joel Habener. These presentations reflected major advances from the in the understanding concepts offered at the last meeting. Other advances of hormone structure/function included the continuing work by Joyce Lustbader on the determination of the three-dimensional structure of hCG, including a new approach using nonisotopic labels for 3-D and 4-D NMR imaging. New insights into biosynthesis of hCG were proposed by Irving Boime. Studies directed at identifying receptor contact regions were presented by Henry Keutmann and David Puett.
Download or read book Microheterogeneity of Glycoprotein Hormones written by B.A. Keel and published by CRC Press. This book was released on 2018-05-04 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eleven contributions review our knowledge of the characterization of glycoprotein hormone microheterogeneity, the relationships between biological activity and microheterogeneity, the endocrinological control mechanisms involved in the production of these forms and the underlying biochemical basis for glycoprotein hormone microheterogeneity. Organized so that the heterogeneity of each hormone from a variety of species is covered in detail, the peptide components and oligosaccaride stuctures of glycoprotein hormones are reviewed, and the heterogeneity of uncombined alpha and beta subunits is discussed.
Download or read book Glycoprotein Hormones written by William W. Chin and published by Serono Symposia USA, Incorporated. This book was released on 1990 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Cloning of Hormone Genes written by Joel F. Habener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peptide hormones are small proteins that regulate cellular metabolism through their specific interactions with tissues of the endocrine, nervous, and immune systems, as well as in embry onic development. During the past ten years, refinements in the techniques of recombinant DNA technology have resulted in the cloning of genes encoding approximately 50 different hormonal and regulatory peptides, including those in which the peptides themselves and the mRNAs encoding the peptides are present in only trace amounts in the tissues of origin. In addition to provid ing the coding sequences of recognized hormonal and regulatory peptides, gene sequencing has uncovered new bioactive peptides encoded in the precursor pro hormones that are then liberated along with the hormonal peptides during cellular cleavages of the precursors. The encoding of multiple peptides in a single mono cistronic mRNA appears to be a genetic mechanism for the gener ation of biologic diversification without requiring amplification of gene sequences. Two of the objectives in the assembly of this book are to pre sent, in one volume, the known primary structures of the genes encoding several of the polypeptide hormones and related regulatory peptides, and to provide an account of the various ap proaches that have been used to identify and select the cloned genes encoding these polypeptides. The contents of the two in troductory chapters are intended to provide the reader with a brief background of the approaches to gene cloning and the struc ture and expression of hormone-encoding genes.
Download or read book Glycoproteins written by Jean Montreuil and published by Elsevier. This book was released on 1995 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian, bacterial, yeast, plant and insect glycoproteins. There are alsotwo chapters on functional aspects (glycoprotein hormones andcollagens). The content of the volume is very comprehensive in that, mostcontributors have focussed on discussing, in depth, the wealthof most recent advances in their field, and referring to previousreviews of older work for background information. This method caneffectively produce a very wide subject coverage in a smallernumber of chapters/volumes. The volume is an importantinformation source for all glycobiologist researchers (seniorinvestigators, post-doctoral fellows and graduate students), andas a good, comprehensive, reference text for scientists working inthe life sciences.
Download or read book Glycoprotein Hormones written by Joyce Werner Lustbader and published by Springer. This book was released on 1994-01-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Glycoproteins I written by J. Montreuil and published by Elsevier. This book was released on 1995-06-23 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part I covers modern advances in the determination of glycoprotein structure and in the biosynthesis of mammalian, bacterial, yeast, plant and insect glycoproteins. There are also two chapters on functional aspects (glycoprotein hormones and collagens). The content of the volume is very comprehensive in that, most contributors have focussed on discussing, in depth, the wealth of most recent advances in their field, and referring to previous reviews of older work for background information. This method can effectively produce a very wide subject coverage in a smaller number of chapters/volumes. The volume is an important information source for all glycobiologist researchers (senior investigators, post-doctoral fellows and graduate students), and as a good, comprehensive, reference text for scientists working in the life sciences.
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Download or read book Structure activity Relationships of Protein and Polypeptide Hormones written by M. Margoulies and published by . This book was released on 1971 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Function of the Gonadotropins written by Kenneth W. McKerns and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September of 1977 scientists from many countries met at the Asticou Inn in Maine to present and discuss papers written especially for this monograph. The presentations were informal and directed to the special interests of the audience in order to generate discussions. The authors, many of whom are pioneers and leaders in their field, then had the oppor tunity to revise their contributions, which were brought together with the edited discussions to form this volume. The basic research studies presented here are important because of the essential role of gonadotropins in regulating the ovary and testis. This monograph will therefore be of interest to those concerned with fertility regulation, population control, possible new methods for contraception, and to those concerned with reproduction in domestic animals. Re searchers in other fields may find this monograph useful, as it has been de termined that gonadotropins are secreted by many tumors and are im plicated in many cancers. Human choriogonadotropin also seems to be found in most, if not all, cells of the human body. The significance of this, however, is unknown.
Download or read book Gigantism and Acromegaly written by Constantine A. Stratakis and published by Academic Press. This book was released on 2021-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Download or read book Microheteroginsity of Glycoprotein Hormones written by Broods A. Keel and published by . This book was released on 1989 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Glycoprotein Hormones written by Jean-Michel Bidart and published by . This book was released on 2000 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Biochemistry of Glycoproteins and Proteoglycans written by William Lennarz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although glycoproteins and proteoglycans have been a subject of re search for many years, it is only during the last five or so years that they have aroused the interest of a very broad cross section of investigators in the biological sciences. The reason for this expanded interest in these molecules is simple: not only are glycoproteins and proteoglycans ubiq uitous, but many are molecules with well-defined and important biological functions. The list of molecules that fall into this category grows daily; interferon, immunoglobulins, certain hormones, many cell surface recep tors, and viral coat proteins are but a few examples. Thus, investigators with interests as diverse as viral replication. cell-cell interactions. poly isoprenoid synthesis, secretory processes, hormone responses, embryonic development, and immunology have become concerned with glycopro teins and proteoglycans. The objective of this book is to summarize the current state of knowledge on the biochemistry of these molecules. Coverage is by no means encyclopedic; rather the thrust is to emphasize the recent ad vances. The first chapter deals primarily with structural work on the oligosaccharide chains of glycoproteins, but it will be apparent in it and in the succeeding two chapters on biosynthesis that not only do structural studies aid biosynthetic investigations, but that studies on biosynthesis often playa major role in elucidation of structure.
Download or read book Heterogeneity of Polypeptide Hormones written by David Rabinowitz and published by . This book was released on 1974 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reproduction in Domestic Animals written by H. H. Cole and published by Elsevier. This book was released on 2013-09-24 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproduction in Domestic Animals, Second Edition discusses the chemistry of gonadotropins and biochemistry of the gonadal hormones. The book presents the immunological characterization of the gonadotropins and the regulation of the secretion of pituitary gonadotropins by the nervous system. The text describes the physiology of reproduction and then discusses the effects of hormones on the development and differentiation of the brain. Another topic of interest is the formation of preovulatory follicles. The section that follows describes the necessity of quantitative female gametes production. The book will provide valuable insights for biologists, zoologists, students, and researchers in the field of animal reproduction.
Download or read book Structure of the Glycoprotein Hormones written by Stanley R. Krystek (Jr) and published by . This book was released on 1989 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
