Download or read book A Statistic of One written by Stephen Hatrak and published by iUniverse. This book was released on 2012-05-11 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Statistic of One: My Walk with Glioblastoma Multiforme traces Stephen Hatraks life from his diagnosis of glioblastoma multiforme, the deadliest of malignant brain tumors, to the present. He chronicles the trials and tribulations he faced and the losses he suffered along his journey. Faith and inner strength are formidable allies in overcoming any tragedy in ones life, and they played vital roles in his struggle. He was told from the start that the he might have twelve months to live; even so, he defi ed the odds and, six years later, is telling his own story. Despite the dire statistics associated with a diagnosis of glioblastoma, there are several stories of long-term survival; these stories gave him hope that this cancer could be tamed. To overcome this challenge in his life, he had to believe in himself and fi nd his inner sixth sense to strengthen his resolve. Along the way, he learned that life with brain cancer could be tough, but that he could be even tougher. What cancer cannot do.separate me from my soul, squash my spirit, and stop the sun from rising in the east and setting in the west; creating new tomorrows and new opportunities. A Statistic of One is an uplifting story of faith and perseverance; how we cope with challenge will determine how we move forward and live life to its fullest.
Download or read book Glioblastoma written by Swapan K. Ray and published by Springer Science & Business Media. This book was released on 2009-10-31 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.
Download or read book Glioblastoma Multiforme written by James Markert and published by Jones & Bartlett Learning. This book was released on 2005 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment of malignant glioma remains a major challenge for neurosurgeons, neurologists, medical oncologists, and radiation oncologists caring for patients with these tumors. Glioblastoma multiforme, the most common type of brain tumor, is also the most deadly -- only five percent of patients or fewer will be alive at five years after diagnosis. This comprehensive new reference is edited by a renowned team consisting of a neurosurgeon, medical oncologist, oncologic surgeon, and radiation oncologist. The book provides basic researchers and clinicians with a contemporary review of the epidemiology, diagnosis, and treatment of glioblastoma multiforme, and also imparts to experienced investigators outside of the field sufficient background to apply their skills to the treatment of this deadly disease. Expert malignant glioma researchers and clinicians provide state-of-the-art chapters on important topics such as molecular genetic classification of glioblastoma, surgical management, stem cell therapy, chemotherapy, angiogenesis, and more.
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Download or read book They Call Me The Miracle The Carmen Rice Story written by Randy R. Harris and published by Ambassador International. This book was released on 2021-10-26 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a major worldwide public health problem and is the second leading cause of death in the United States. In 2018, there were seventeen million new cancer cases and 9.5 million cancer deaths worldwide. Seemingly, everyone has been affected by or knows of someone who is affected by the disease. In 2004, doctors discovered that Carmen Rice had a stage 4 Glioblastoma Multiforme brain tumor, one of the deadliest of all cancers—the same cancer which killed John McCain, Edward Kennedy, and Beau Biden. After being diagnosed with a glioblastoma tumor, twenty-nine-year-old Brittany Maynard made headline news when she moved to Oregon to die with dignity. Carmen’s doctor gave her six months to live, but with her faith in God and tenacious spirit, Carmen just kept beating the odds. After all these years, Carmen is “off the map” and into uncharted territory. They Call Me "The Miracle" is her story.
Download or read book Imaging Gliomas After Treatment written by Tommaso Scarabino and published by Springer Science & Business Media. This book was released on 2011-11-22 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is a detailed guide to the imaging appearances of gliomas following treatment with neurosurgery, radiation therapy, and chemotherapy. Normal and pathological findings are displayed in detailed MR images that illustrate the potential modifications due to treatment. Particular emphasis is placed on characteristic appearances on the newer functional MR imaging techniques, including MR spectroscopy, diffusion-weighted imaging, and perfusion imaging. These techniques are revolutionizing neuroradiology by going beyond the demonstration of macroscopic alterations to the depiction of preceding metabolic changes at the cellular and subcellular level, thereby allowing earlier and more specific diagnosis. A key section comprising some 40 clinical cases and more than 500 illustrations offers an invaluable clinical and research tool not only for neuroradiologists but also for neurosurgeons, radiotherapists, and medical oncologists.
Download or read book Fast Facts Glioblastoma written by M. McNamara and published by Karger Medical and Scientific Publishers. This book was released on 2020-02-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma (also known as glioblastoma multiforme) is a malignant intrinsic tumor thought to arise from populations of stem/progenitor cells in the brain. It is the most common aggressive intrinsic brain tumor in adults, with the potential to spread rapidly within the brain. Patients with glioblastoma face a poor prognosis, with median overall survival of approximately 15 months. However, our growing understanding of the molecular biology of gliomas means that this outlook may be improving. The identification of clinically relevant subgroups defined by specific genetic mutations is challenging the traditional delineation between low- and high-grade gliomas that has been based on histological appearance and imaging. Indeed, it is becoming clear that, as a molecular entity, a glioblastoma, which by traditional classification is a grade IV glioma, may present with a lower grade initially and then become more aggressive – an important addition to the established concept. The care of a patient with a glioblastoma requires a coordinated approach delivered by a multidisciplinary team, with the aim of maintaining quality of life for as long as possible. Here, we provide a concise overview of the diagnosis and management of glioblastoma, as well as discussion of our emerging understanding of the molecular drivers that are helping us to delineate different patient subgroups. These subgroups will, hopefully, allow more targeted treatments in the future. This resource will be of interest to all those involved in caring for patients with this aggressive brain tumor, including neurologists, neurosurgeons, neuro-oncologists, radiation oncologists, palliative care specialists, specialist nurses and medical students. Contents: • Epidemiology, pathophysiology and classification • Clinical presentation • Diagnosis • Management • Treatment of associated conditions • Emerging research and treatment
Download or read book Re Irradiation New Frontiers written by Carsten Nieder and published by Springer. This book was released on 2016-10-25 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.
Download or read book Glioblastoma Multiforme written by Isabelle M. Germano and published by Nova Science Publishers. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides basic researchers and clinicians with a contemporary review of personalised medicine for the diagnosis and treatment of Glioblastoma Multiforme (GBM), the most common and most aggressive type of brain tumor. Over the past decade, there has been an explosion of basic and clinical research revolving around GBM, resulting in improved outcomes and, most importantly, significant advances in our ability to better understand this disease to formulate personalised medical treatment for each patient. It is important to note that the word multiforme means "of many forms or appearances", implying that "one treatment will not fit all". Data from a variety of sources show that medical decisions and interventions must be tailored to the individual patient to obtain the greatest outcome. In this book, the diagnostic techniques and treatment options for patients with GBM are reviewed in state-of-the-art chapters written by expert researchers and clinicians in the field focusing on molecular genetic classification, surgical management, chemotherapy, radiation, nutrition, immune-therapy, and more. Many new therapeutic options are described and reviewed, confirming that not only does each patient needs to have personalised treatment, but also that a single treatment alone will not be sufficient; multiple mechanisms are involved and tumor biology changes over time. Hopefully, this book will educate and stimulate readers' knowledge and lead to new avenues of investigation and therapeutic success.
Download or read book Surviving terminal Cancer written by Ben A. Williams and published by Createspace Independent Publishing Platform. This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An account of dealing with glioblastoma brain cancer, along with the information needed to survive it
Download or read book Tumors of the Central Nervous System Volume 2 written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2011-04-03 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.
Download or read book Jack s Story written by Ken Fleming and published by . This book was released on 2019-10-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The life and death of Jack Fleming through his battle with glioblastoma multiforme (GBM) brain cancer as told by his father, Ken. This is the story of a very brave young man. I was with him when he took his first breath and I was with him when he took his last. One was a moment of exquisite pleasure and the other was a moment of unimaginable pain. He gave life, and particularly the last two years struggling with terminal brain cancer, his best shot. He never stopped smiling; never gave up; never said no more. He was diagnosed with glioblastoma multiforme (GBM) brain cancer on a cold, wet and wintry 8 July 2016. He was given 12 months to live. We got 22 months. In December 2017 we found out that none of the treatments were working and he was unlikely to live much longer. On 28 March 2018, we were told it was all over. He died at 1.45 pm on 15 April 2018. I promised him I would write a book. I kept my promise. -- Ken Fleming - JACK EVAN FLEMING 25 November 1996 - 15 April 2018 RIP Praise for Jack's Story "Jack's Story is gripping and confronting. Well done for having the courage to write it and get it out there in the public space. I'm sure many other families and health professionals will benefit from reading this book. It was a real tribute to Jack...and also demonstrated you're didn't leave a stone unturned in trying to find a solution to this aggressive cancer." Dr Nick Cooling "Thank you for sharing Jack's Story. I'm deeply sorry to hear about your son's journey with cancer. As you know glioblastoma cancer has touched my life and those that I love dearly. I can only imagine how difficult this process is for you and your family. It sounds like Jack was surrounded with support and indeed possessed courage at its best. I know that the grieving process never quite ends, but in due time, the thought of your son will bring a smile to your lips sooner than a tear to your eye. Our sons gave us so much more than they knew, so much for us to cherish. Our memories of them will always be with us. Please know that Jill and I will keep you in our thoughts and prayers. We're in this with you. God Bless you." Joseph R. Biden. Jr. "I would like to give my condolences to your family as no family should have to go through what your family endured. Taking the pain from your son's story and turning it into a moving and beautifully honest book takes a lot of courage. I appreciate the bravery it took to write this book about what it is really like inside a life with glioblastoma multiforme." Senator John McCain "I read Jack's story in one night ...couldn't put it down ... and despite knowing how it all ended, I was willing there to be a twist and turn on each page that would see a miracle happen. What a truly incredible story of hope, love, courage and ultimate tragedy." Katie Murray "I'm so sorry that despite all the expert advice and treatment he received that no more could be done to save him. It is stories like these, and patients like Jack, that drive us to continue our work and research and clinical trials to try to find new and better treatments to counter this awful disease. Let's hope we can make some more break throughs in memory of all the children and young adults like Jack." Dr David Ziegler
Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.
Download or read book Navigating Glioblastoma written by Sally Connolly and published by McFarland. This book was released on 2020-07-10 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: A stale marriage. A deadly diagnosis. For Sally Connolly, three years of struggle followed her husband Peter's surgery for terminal brain cancer at age 61. Choosing treatment options that interfered least with his career, Peter focused his limited energy on work, with little left for his family, further straining the marriage during his remaining days. Connolly's clear-eyed and affecting memoir recounts their wrangling over gender roles, money management, domestic decisions and lifestyle changes. Through their traumatic journey, they find humor and comfort in unexpected places.
Download or read book Novel Treatment Strategies for Glioblastoma written by Stanley Stylli and published by Mdpi AG. This book was released on 2021-12-21 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.
Download or read book Proceedings of 2021 International Conference on Medical Imaging and Computer Aided Diagnosis MICAD 2021 written by Ruidan Su and published by Springer. This book was released on 2022-08-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers virtually all aspects of image formation in medical imaging, including systems based on ionizing radiation (x-rays, gamma rays) and non-ionizing techniques (ultrasound, optical, thermal, magnetic resonance, and magnetic particle imaging) alike. In addition, it discusses the development and application of computer-aided detection and diagnosis (CAD) systems in medical imaging. Also there will be a special track on computer-aided diagnosis on COVID-19 by CT and X-rays images. Given its coverage, the book provides both a forum and valuable resource for researchers involved in image formation, experimental methods, image performance, segmentation, pattern recognition, feature extraction, classifier design, machine learning / deep learning, radiomics, CAD workstation design, human–computer interaction, databases, and performance evaluation.
Download or read book Intracranial and Spinal Radiotherapy written by Lia M. Halasz and published by Springer Nature. This book was released on 2021-03-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.
