Download or read book Genomic Perl written by Rex A. Dwyer and published by Cambridge University Press. This book was released on 2003 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.

Download or read book Approaches and applications in plant genome assembly and sequence analysis written by Weihua Pan and published by Frontiers Media SA. This book was released on 2023-04-06 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genome Plasticity in Health and Disease written by and published by Academic Press. This book was released on 2020-04-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery. Examines the role of genome plasticity across a range of disease types, from cardiovascular disease, to cancer and neuropsychiatric disorders Adopts an interdisciplinary approach, with expert contributions across the spectrum of basic science and disease relevance to drug discovery

Download or read book Nuclear Genome Stability DNA Replication Telomere Maintenance and DNA Repair written by Maria Isabel Nogueira Cano and published by Frontiers Media SA. This book was released on 2022-03-09 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genome Annotation written by Jung Soh and published by CRC Press. This book was released on 2016-04-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of individualized medicine, advanced crops, and new and sustainable energy sources requires thoroughly annotated genomic information and the integration of this information into a coherent model. A thorough overview of this field, Genome Annotation explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. The book initially takes you through the last 16 years since the sequencing of the first complete microbial genome. It explains how current analysis strategies were developed, including sequencing strategies, statistical models, and early annotation systems. The authors then present visualization techniques for displaying integrated results as well as state-of-the-art annotation tools, including MAGPIE, Ensembl, Bluejay, and Galaxy. They also discuss the pipelines for the analysis and annotation of complex, next-generation DNA sequencing data. Each chapter includes references and pointers to relevant tools. As very few existing genome annotation pipelines are capable of dealing with the staggering amount of DNA sequence information, new strategies must be developed to accommodate the needs of today’s genome researchers. Covering this topic in detail, Genome Annotation provides you with the foundation and tools to tackle this challenging and evolving area. Suitable for both students new to the field and professionals who deal with genomic information in their work, the book offers two genome annotation systems on an accompanying downloadable resources.

Download or read book The Globe Artichoke Genome written by Ezio Portis and published by Springer. This book was released on 2019-06-08 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest information on the genetics and genomics of the globe artichoke. It focuses on the latest findings, tools and strategies employed in genome sequencing, physical map development and QTL analyses, as well as genomic resources. The re-sequencing of four globe artichoke genotypes, representative of the core varietal types in cultivation, as well as the genotype of cultivated cardoon, has recently been completed. Here, the five genomes are reconstructed at the chromosome scale and annotated. Moreover, functional SNP analyses highlight numerous genetic variants, which represent key tools for dissecting the path from sequence variation to phenotype, as well as for designing effective diagnostic markers. The wealth of information provided here offers a valuable asset for scientists, plant breeders and students alike.

Download or read book Genome Mapping written by Jon Schiller and published by CreateSpace. This book was released on 2010-08-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your author decided to write this book about Genome Mapping after attending a Dinner Lecture for Caltech Alumni living in the Santa Barbara County area of Mid-Coast California Dr David Barker, BS 1963 Caltech & PhD in Biochemistry from Brandeis University, gave a slide presentation on DNA sequencing and what it can tell you. In my quest for more knowledge about this exciting area of biochemistry, I sought more information about Genome Mapping and Entire DNA Sequencing from the Google and Yahoo search engines. As is common in Internet Research, I found a great deal of research was taking place worldwide. It was my objective to summarize this research in this book so my readers could learn what is happening and where to find more information about this important area of Biochemistry. One possibility is modifying your DNA to reduce susceptibility to certain diseases..perhaps we will be able to reduce our risk of cancer. One of my good friends died recently of Prostate Cancer, so my interest in combating Cancer has been intensified.

Download or read book The Rubber Tree Genome written by Minami Matsui and published by Springer Nature. This book was released on 2020-04-18 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the first comprehensive compilation of genome research on the Hevea brasiliensis rubber tree. The genomes of Hevea tree clones (cultivars) are described by three major international groups. Chapters on omics-driven investigations address a broad range of topics including genome annotation and utilisation, transcriptome and gene family analysis, genetic mapping, metabolic pathways in latex and molecular breeding. Additionally, an overview of fundamental rubber biology, especially on laticifers, provides a historical background that is relevant to rubber genome analysis. The book concludes with several perspectives on the future needs of rubber investigations and prospects of rubber genomics. Given the scope of topics, this book will appeal to researchers and university students working in genomics and biotechnology of the rubber tree, and to rubber breeders with an interest in non-conventional approaches to trait analysis, selection and breeding.

Download or read book The Lupin Genome written by Karam B. Singh and published by Springer Nature. This book was released on 2020-01-30 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on lupin genomics primarily focuses on the narrow-leafed lupin (NLL), and details the genomic resources that have been developed and how they are currently being used to help advance both fundamental and applied research on NLL in areas ranging from its domestication to plant–microbe interactions and syntenic relationships between NLL and other legume crops. It also reports on genomic efforts being pursued with regard to other lupin crops. Lupins are important ecological ‘engineers’: they can colonise and thrive in low-nutrient soils due to their ability to fix atmospheric nitrogen in symbiosis with bacteria and efficiently take up phosphorous. Recently, lupins have attracted considerable interest, not only because of their value for sustainable farming as a break crop, but also as a potential ‘super food’ for fighting major health issues in connection with diabetes and obesity. Narrow-leafed lupin is the main grain legume crop, grown primarily in Australia, and was therefore selected for the development of a reference lupin genome and associated genomic resources. Its genome has recently been sequenced with a focus on the gene-rich space, which has advanced the development of new breeding tools for the improvement of NLL and related lupin crops.

Download or read book Bioinformatics of Genome Regulation and Systems Biology written by Yuriy L. Orlov and published by Frontiers Media SA. This book was released on 2020-09-17 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Genome Informatics 2008 written by Jonathan Arthur and published by Imperial College Press. This book was released on 2008-01-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers presented at the 19th International Conference on Genome Informatics (GIW 2008) held at the Marriott Surfers Paradise Resort, Gold Coast, Queensland, Australia from December 1 to 3, 2008. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 19 years, GIW is the longest-running international bioinformatics conference.

Download or read book Genome Mining and Marine Microbial Natural Products written by Kui Hong and published by MDPI. This book was released on 2020-01-07 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two review papers, eight research articles, and one brief report were published in this Special Issue. They showed the rich resources that are present within the genomes of marine microorganisms and discussed the use of recently developed tools and technologies to exploit this genetic richness. Examples include the rational supply of precursors according to the relevant biosynthetic pathway and stress driven discovery together with the use of histone deacetylase inhibitors to facilitate the discovery of new bioactive molecules with potential biopharmaceutical applications. We believe that the content of this Special Issue reflects the current state-of-the-art research in this area and highlights the interesting strategies that are being employed to uncover increasing numbers of exciting novel compounds for drug discovery from marine genetic resources.

Download or read book Human Genome Epidemiology 2nd Edition written by Muin Khoury and published by Oxford University Press. This book was released on 2010-01-20 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace. With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.

Download or read book Human Genome Epidemiology 2nd Edition written by Muin Khoury and published by Oxford University Press. This book was released on 2010-01-20 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. It provides a foundation that should help researchers, policy makers and practitioners integrate genomics into medical and public health practice.

Download or read book Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R written by Gabriel Valiente and published by CRC Press. This book was released on 2009-04-08 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis of genomic, transcriptomic, proteomic, metabolomic

Download or read book Aquaculture Genome Technologies written by Zhanjiang (John) Liu and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics is a rapidly growing scientific field with applications ranging from improved disease resistance to increased rate of growth. Aquaculture Genome Technologies comprehensively covers the field of genomics and its applications to the aquaculture industry. This volume looks to bridge the gap between a basic understanding of genomic technology to its practical use in the aquaculture industry.

Download or read book Advances in Genome Assembly for Fisheries and Aquaculture written by Liang Guo and published by Frontiers Media SA. This book was released on 2022-03-28 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: