Download or read book Genetic Distance written by James Crow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included in the program of The Fourth International Congress of Human Genetics, held in Paris on September ~-ll, 1971, was a Workshop of Genetic Distance. This session, or ganized by Newton E. Morton, included several papers anrl a discussion under the general chairmanship of James F. Crow. Many of the participants and members of the audience asled at the time that the papers be printed so as to have a per manent record. It has not been practical to record the dis cussion, but all the papers originally presented are includ ed in this volume. The idea behind the Workshop was to take advantage of the large number of people who would be attending the Con gress and bring together those who were interested in human population structure and measures of genetic distance. The emphasis was on methodology; the number of metbods almost equals the number of persons working in the field. The Workshop offered an opportunity to present and discuss the various procedures and review their accomplishments. The aim has been to have these papers either present the methods themselves, or give references as to where they can be found.

Download or read book Molecular Evolutionary Genetics written by Masatoshi Nei and published by Columbia University Press. This book was released on 1987 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: -- "The Scientist"

Download or read book Molecular Systematics of Fishes written by Thomas D. Kocher and published by Elsevier. This book was released on 1997-07-10 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequenced biological macromolecules have revitalized systematic studies of evolutionary history. Molecular Systematics of Fishes is the first authoritative overview of the theory and application of these sequencing data to fishes. This volume explores the phylogeny of fishes at multiple taxonomic levels, uses methods of analysis of molecular data that apply both within and between fish populations, and employs molecule-based phylogenies to address broader questions of evolution. Targeted readers include ichthyologists, marine scientists, and all students, faculty, and researchers interested in fish evolution and ecology and vertebrate systematics. - Focuses on the phylogeny and evolutionary biology of fishes - Contains phylogenies of fishes at multiple taxonomic levels - Applies molecule-based phylogenies to broader questions of evolution - Includes methods for critique of analysis of molecular data

Download or read book Analysis of Complex Disease Association Studies written by Eleftheria Zeggini and published by Academic Press. This book was released on 2010-11-17 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. Analysis of Complex Disease Association Studies will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available. - Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests - Extensive list of references including links to tutorial websites - Case studies and Tips and Tricks

Download or read book Genetics for Surgeons written by Patrick John Morrison and published by Remedica. This book was released on 2005 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).

Download or read book Evolutionary Biology written by Max K. Hecht and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifteen volumes and one supplement have now appeared in the series known as Evolutionary Biology. The editors continue to seek critical reviews, original papers, and commentaries on controversial topics. It is our aim to publish papers primarily of greater length and depth than those normally published by society journals and quarterlies. The editors make every attempt to solicit manuscripts on an international scale and to see that no facet of evolutionary biology-classical or modern-is slighted. Manuscripts should be sent to anyone of the following: Max K. Hecht, Department of Biology, Queens College of the City University of New York, Flushing, New York 11367; Bruce Wallace, Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061; Ghillean T. Prance, New York Botanical Garden, Bronx, New York 10458. The Editors vII Contents 1. Patterns of Neotropical Plant Species Diversity . . . . . . . . . . . . . . . . . . . . . . 1 Alwyn H. Gentry Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I Sites and Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Sample Sites . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Identifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Structural Trends . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Community Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Floristic Composition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Dispersal Ecology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Pollination Strategies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Appendix. Sites and Communities Studied . . . . . . . . . . . . . . . . . . . . . . . . . . 50 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 2. Evolution on a Petri Dish: The Evolved fJ-Galactosidase System as a Model for Studying Acquisitive Evolution in the Laboratory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ••. . . . . . . . . . . . . . . . . . . 85 Barry G. Hall Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Approaches to Molecular Evolution . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 The Descriptive Approach . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 The Experimental Approach . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 Mechanisms for the Acquisition of New Genetic Material. . . . . 97 The EBG System a s a Model for Acquisitive Evolution . . . . . . . 98 The Unevolved Enzyme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Download or read book Biometry written by Robert R. Sokal and published by Macmillan. This book was released on 1995 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers students with little background in statistical analysis an introduction to a variety of statistical concepts and methods. In addition to the incorporation of computer calculation, this new edition expands on a number of important topics, including the revised Kolmogrov-Smirnov test.

Download or read book The History and Geography of Human Genes written by L L Cavalli-sforza and published by Princeton University Press. This book was released on 2018-06-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hailed as a breakthrough in the understanding of human evolution, The History and Geography of Human Genes offers the first full-scale reconstruction of where human populations originated and the paths by which they spread throughout the world. By mapping the worldwide geographic distribution of genes for over 110 traits in over 1800 primarily aboriginal populations, the authors charted migrations and devised a clock by which to date evolutionary history. This monumental work is now available in a more affordable paperback edition without the myriad illustrations and maps, but containing the full text and partial appendices of the authors' pathbreaking endeavor.

Download or read book Geographical Genetics MPB 38 written by Bryan K. Epperson and published by Princeton University Press. This book was released on 2003-08-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Population genetics has made great strides in applying statistical analysis and mathematical modeling to understand how genes mutate and spread through populations over time. But real populations also live in space. Streams, mountains, and other geographic features often divide populations, limit migration, or otherwise influence gene flow. This book rigorously examines the processes that determine geographic patterns of genetic variation, providing a comprehensive guide to their study and interpretation. Geographical Genetics has a unique focus on the mathematical relationships of spatial statistical measures of patterns to stochastic processes. It also develops the probability and distribution theory of various spatial statistics for analysis of population genetic data, detailing exact methods for using various spatial features to make precise inferences about migration, natural selection, and other dynamic forces. The book also reviews the experimental literature on the types of spatial patterns of genetic variation found within and among populations. And it makes an unprecedented strong connection between observed measures of spatial patterns and those predicted theoretically. Along the way, it introduces readers to the mathematics of spatial statistics, applications to specific population genetic systems, and the relationship between the mathematics of space-time processes and the formal theory of geographical genetics. Written by a leading authority, this is the first comprehensive treatment of geographical genetics. It is a much-needed guide to the theory, techniques, and applications of a field that will play an increasingly important role in population biology and ecology.

Download or read book The Human Genome written by Julia E. Richards and published by Academic Press. This book was released on 2010-12-12 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, Third Edition will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome, Second Edition includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information. - Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students - Full, 4-color illustration program enhances and reinforces key concepts and themes - Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers

Download or read book The Phylogenetic Handbook written by Marco Salemi and published by Cambridge University Press. This book was released on 2009-03-26 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: A broad, hands on guide with detailed explanations of current methodology, relevant exercises and popular software tools.

Download or read book Genes peoples and languages written by Luigi Luca Cavalli- Sforza and published by . This book was released on 2006 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Understanding Racial and Ethnic Differences in Health in Late Life written by National Research Council and published by National Academies Press. This book was released on 2004-09-08 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.

Download or read book The Neolithic Transition and the Genetics of Populations in Europe written by Albert J. Ammerman and published by Princeton University Press. This book was released on 2014-07-14 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the shift from hunting and gathering to agriculture as a way of life and the implications of this neolithic transition for the genetic structure of European populations. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Download or read book Genetic Structure and Selection in Subdivided Populations MPB 40 written by François Rousset and published by Princeton University Press. This book was released on 2013-02-15 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Various approaches have been developed to evaluate the consequences of spatial structure on evolution in subdivided populations. This book is both a review and new synthesis of several of these approaches, based on the theory of spatial genetic structure. François Rousset examines Sewall Wright's methods of analysis based on F-statistics, effective size, and diffusion approximation; coalescent arguments; William Hamilton's inclusive fitness theory; and approaches rooted in game theory and adaptive dynamics. Setting these in a framework that reveals their common features, he demonstrates how efficient tools developed within one approach can be applied to the others. Rousset not only revisits classical models but also presents new analyses of more recent topics, such as effective size in metapopulations. The book, most of which does not require fluency in advanced mathematics, includes a self-contained exposition of less easily accessible results. It is intended for advanced graduate students and researchers in evolutionary ecology and population genetics, and will also interest applied mathematicians working in probability theory as well as statisticians.

Download or read book Avian Influenza Virus written by Erica Spackman and published by Springer Science & Business Media. This book was released on 2008-02-28 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the growing global fear of a major pandemic, avian influenza (AI) virus research has greatly increased in importance. In Avian Influenza Virus, an expert team of researchers and diagnosticians examine the fundamental, yet essential, virological methods for AI virus research and diagnostics as well as some of the newest molecular procedures currently used for basic and applied research. They present exciting, cutting-edge new methods that focus both on studying the virus itself and on work with avian hosts, an area greatly lacking in research.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: