Download or read book Genetic Analysis of Complex Traits Using SAS written by Arnold Myron Saxton and published by SAS Press. This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arnold Saxton, Ph.D., the editor of this volume, is a professor of animal science at the University of Tennessee, Knoxville. He has assembled 16 coauthors from around the world to create this unique, example-rich compilation that demonstrates how one can use SAS and SAS/Genetics to extract answers from quantitative and molecular genetics data.
Download or read book Genetic Data Analysis for Plant and Animal Breeding written by Fikret Isik and published by Springer. This book was released on 2017-09-09 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the gap between textbooks of quantitative genetic theory, and software manuals that provide details on analytical methods but little context or perspective on which methods may be most appropriate for a particular application. Accordingly this book is composed of two sections. The first section (Chapters 1 to 8) covers topics of classical phenotypic data analysis for prediction of breeding values in animal and plant breeding programs. In the second section (Chapters 9 to 13) we provide the concept and overall review of available tools for using DNA markers for predictions of genetic merits in breeding populations. With advances in DNA sequencing technologies, genomic data, especially single nucleotide polymorphism (SNP) markers, have become available for animal and plant breeding programs in recent years. Analysis of DNA markers for prediction of genetic merit is a relatively new and active research area. The algorithms and software to implement these algorithms are changing rapidly. This section represents state-of-the-art knowledge on the tools and technologies available for genetic analysis of plants and animals. However, readers should be aware that the methods or statistical packages covered here may not be available or they might be out of date in a few years. Ultimately the book is intended for professional breeders interested in utilizing these tools and approaches in their breeding programs. Lastly, we anticipate the usage of this volume for advanced level graduate courses in agricultural and breeding courses.
Download or read book Molecular Dissection of Complex Traits written by Andrew H. Paterson and published by CRC Press. This book was released on 2019-09-17 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in thi
Download or read book Validating Clinical Trial Data Reporting with SAS written by Carol I. Matthews and published by SAS Institute. This book was released on 2008 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This indispensable guide focuses on validating programs written to support the clinical trial process from after the data collection stage to generating reports and submitting data and output to the Food and Drug Administration.
Download or read book Genetic Dissection of Complex Traits written by D.C. Rao and published by Academic Press. This book was released on 2008-04-23 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more
Download or read book SAS for Mixed Models written by Walter W. Stroup and published by SAS Institute. This book was released on 2018-12-12 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the power of mixed models with SAS. Mixed models—now the mainstream vehicle for analyzing most research data—are part of the core curriculum in most master’s degree programs in statistics and data science. In a single volume, this book updates both SAS® for Linear Models, Fourth Edition, and SAS® for Mixed Models, Second Edition, covering the latest capabilities for a variety of applications featuring the SAS GLIMMIX and MIXED procedures. Written for instructors of statistics, graduate students, scientists, statisticians in business or government, and other decision makers, SAS® for Mixed Models is the perfect entry for those with a background in two-way analysis of variance, regression, and intermediate-level use of SAS. This book expands coverage of mixed models for non-normal data and mixed-model-based precision and power analysis, including the following topics: Random-effect-only and random-coefficients models Multilevel, split-plot, multilocation, and repeated measures models Hierarchical models with nested random effects Analysis of covariance models Generalized linear mixed models This book is part of the SAS Press program.
Download or read book The Essential PROC SQL Handbook for SAS Users written by Katherine Prairie and published by SAS Institute. This book was released on 2005-06-21 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Navigate the world of the powerful SQL procedure with Katherine Prairie's Essential PROC SQL Handbook for SAS Users. Written in an easy-to-use, logical format, this comprehensive reference focuses on the functionality of the procedure, as well as the accomplishment of common tasks using PROC SQL, enabling readers to quickly develop and enhance their SQL skills. Features include more than 300 examples of PROC SQL code, plus queries and diagrams showing how the statements are processed, tips and techniques highlighting "need-to-know" concepts, and an appendix designed specifically for SQL Pass-Through Facility and SAS/ACCESS users. This practical guide is written for SAS users of all levels who want to learn how to integrate the SQL procedure into their Base SAS and/or SAS/ACCESS programs as well as SQL programmers who want to adapt their current skills to SAS. This book is part of the SAS Press program.
Download or read book Pharmaceutical Statistics Using SAS written by Alex Dmitrienko and published by SAS Institute. This book was released on 2007 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.
Download or read book SAS for Linear Models written by Ramon Littell and published by John Wiley & Sons. This book was released on 2002-05-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features and capabilities of the REG, ANOVA, and GLM procedures are included in this introduction to analysing linear models with the SAS System. This guide shows how to apply the appropriate procedure to data analysis problems and understand PROC GLM output. Other helpful guidelines and discussions cover the following significant areas: Multivariate linear models; lack-of-fit analysis; covariance and heterogeneity of slopes; a classification with both crossed and nested effects; and analysis of variance for balanced data. This fourth edition includes updated examples, new software-related features, and new material, including a chapter on generalised linear models. Version 8 of the SAS System was used to run the SAS code examples in the book. * Provides clear explanations of how to use SAS to analyse linear models * Includes numerous SAS outputs * Includes new chapter on generalised linear models * Uses version 8 of the SAS system This book assists data analysts who use SAS/STAT software to analyse data using regression analysis and analysis of variance. It assumes familiarity with basic SAS concepts such as creating SAS data sets with the DATA step and manipulating SAS data sets with the procedures in base SAS software.
Download or read book Genetic Analysis of Complex Traits Affective disorders written by and published by . This book was released on 1989 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Architecture and Evolution of Complex Traits and Diseases in Diverse Human Populations written by Mashaal Sohail and published by Frontiers Media SA. This book was released on 2022-03-31 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Statistical Methods for the Genetic Dissection of Complex Traits in Plants written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2024-01-26 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.
Download or read book DNA Microarrays Part A Array Platforms and Wet Bench Protocols written by and published by Elsevier. This book was released on 2011-08-19 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician. Provides an overview of platforms Includes experimental design and wet bench protocols Presents statistical and data analysis methods, array databases, data visualization and meta-analysis
Download or read book Association Mapping in Plants written by Nnadozie C. Oraguzie and published by Springer Science & Business Media. This book was released on 2007-01-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides both basic and advanced understanding of association mapping and an awareness of population genomics tools to facilitate mapping and identification of the underlying causes of quantitative trait variation in plants. It acts as a useful review of the marker technology, the statistical methodology, and the progress to date. It also offers guides to the use of single nucleotide polymorphisms (SNPs) in association studies.
Download or read book Linear Selection Indices in Modern Plant Breeding written by J. Jesus Céron-Rojas and published by Springer. This book was released on 2018-09-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the linear selection index (LSI) theory and its statistical properties. It addresses the single-stage LSI theory by assuming that economic weights are fixed and known - or fixed, but unknown - to predict the net genetic merit in the phenotypic, marker and genomic context. Further, it shows how to combine the LSI theory with the independent culling method to develop the multistage selection index theory. The final two chapters present simulation results and SAS and R codes, respectively, to estimate the parameters and make selections using some of the LSIs described. It is essential reading for plant quantitative geneticists, but is also a valuable resource for animal breeders.
Download or read book Modeling Demographic Processes in Marked Populations written by David L. Thomson and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, biologists and statisticians come together in an interdisciplinary synthesis with the aim of developing new methods to overcome the most significant challenges and constraints faced by quantitative biologists seeking to model demographic rates.
Download or read book Strain comparisons in aquaculture species written by Ponzoni and published by WorldFish. This book was released on with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: