Download or read book Principles of Gene Manipulation written by R. W. Old and published by Univ of California Press. This book was released on 1981 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Download or read book Principles of Gene Manipulation and Genomics written by Sandy B. Primrose and published by John Wiley & Sons. This book was released on 2006-02-10 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.
Download or read book An Introduction to Genetic Engineering written by Desmond S. T. Nicholl and published by Cambridge University Press. This book was released on 2002-02-07 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author presents a basic introduction to the world of genetic engineering. Copyright © Libri GmbH. All rights reserved.
Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Download or read book Genetic Manipulation written by Werner Arber (Microbiologist) and published by Cambridge University Press. This book was released on 1984-03 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty-three papers by the Committee on Genetic Experimentation (COGENE) review recent advances in experimental studies on microorganisms, plants and animals.
Download or read book Gene Cloning and Manipulation written by Christopher Howe and published by Cambridge University Press. This book was released on 2007-07-12 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to reflect advances in the field, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Written for advanced undergraduates, graduates and scientists who want to use this technology, emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. An introduction to the basic biochemical principles is presented first. Then PCR and cloning using E. coli hosts and plasmid, phage and hybrid vectors are described, followed by the generation and screening of libraries and how to modify, inactivate or express cloned sequences. Finally genetic manipulation in a range of other organisms is discussed, including other bacteria, fungi, algae and plants, insects and mammals. A series of 'real-life' biological problems are also presented to enable readers to assess their understanding of the material and to prepare for exams.
Download or read book Experimental Manipulation of Gene Expression written by Masayori Inouye and published by Academic Press. This book was released on 2014-06-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.
Download or read book Genetic Manipulation written by J. M. Grange and published by John Wiley & Sons. This book was released on 2009-07-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic manipulation is no longer the province of the specialized researcher. It is finding widespread application in all fields of medicine and biology. Nevertheless, application of these relatively new techniques to new areas of research is often fraught with unexpected problems and difficulties. Based on the Society for Applied Bacteriology's Autumn 1989 Conference, this unique volume covers a wide and very up-to-date range of techniques used in genetic engineering. These include the isolation and analysis of DNA and RNA from cells and tissues, the selection and use of phage and plasmic vectors for cloning DNA, the cloning procedures, the production and screening of genomic libraries, the production and use of DNA probes, the polymerase chain reaction and the synthesis of 'designer' genes. This volume contains many examples of the applications of the above and other techniques for genetic manipulation, to subjects as diverse as plant pathology, forensic science, bacterial taxonomy, cardiac research, diagnostic microbiology, food hygiene and sewage treatment.
Download or read book Principles of Gene Manipulation and Genomics written by Sandy B. Primrose and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.
Download or read book Genetic Manipulation of the Nervous System written by and published by Elsevier. This book was released on 1995-11-24 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas. The recent development of Gene Therapy procedures which allow specific genes to be delivered to human patients who lack functional copies of them is of major therapeutic importance. In addition such gene delivery methods can be used in other organisms to define the function of particular genes. These studies are of particular interest in the nervous system where there are many incurable diseases like Alzheimer's and Parkinson's diseases which may benefit from therapies of this kind. Unfortunately gene delivery methods for use in the nervous system have lagged behind those in other systems due to the fact that the methods developed in other systems are often not applicable to cells like neurons which do not divide. This book discusses a wide range of methods which have now been developed to overcome these problems and allow safe and efficient delivery of particular genes to the brain. Methods discussed include virological methods, physical methods (such as liposomes) and the transplantation of genetically modified cells. In a single volume therefore this book provides a complete view of these methods and indicates how they can be applied to the development of therapies for treating previously incurable neurological disorders.
Download or read book Gene Manipulation in Plant Improvement II written by J. Perry Gustafson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are clearly many directions in which the further development of the GUS gene fusion system can progress. Some of these have been outlined above, but others can be imagined. There are no reasons to limit our conceptions of the use of GUS gene fusions to analysis and manipulation of single genes. We can envision numerous marked genes - perhaps with several new fusion systems - giving valuable information about gene interaction, or population structure. The study of plan- pathogen and plant symbiont interactions can progress rapidly with simple quantitative markers for genes and individuals. We can imagine ways of using gene fusions to report on crop physiology or other complex phenotypes, thereby enhancing the accuracy and speed of screening. Introduction of the biosynthetic pathway for glucuronide detoxification by expressing genes for the UDP-glucuronyl transferases in plants may result in novel mechanisms for plants to deal with xenobiotics such as insecticides or herbicides. Synthesis of substrates, which until now has been performed chemicall- resulting in expensive compounds - can be done biosynthetically. This should make the system not only the most powerful gene fusion system for agriculture, but also the most accessible.
Download or read book Gene Manipulation and Expression written by Robert E. Glass and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents selected papers from the international symposium on "Gene Manipulation and Expression" held in the Bechyne Castle, in South Bohemia, Czechoslovakia, on September 3 to 7, 1984. The symposium was sponsored by Academician J. Riman, vicepresident of the Czechoslovak Academy of Sci ences and director of the Institute of Molecular Genetics of the Czechoslovak Academy of Sciences, and by corresponding member of the Czechoslovak Academy of Sciences Prof. V. Krumphanzl, president of the Czechoslovak Society for Microbiology and director of the Institute of Microbiology of the Czechoslovak Academy of Sciences, with Dr. K. Mikulik of the same Institute acting as chairman of the Organizing Committee. The book is divided into four parts entitled: (l) Rearrangement of prokaryotic genetic material and DNA cloning vectors; (2) DNA-Dependent RNA polymerase in prokaryotes: structure and function; (3) The role of cAMP in gene expression; (4) Translational control of gene expression. We wish to thank all participants who con tributed to this volume. We should also like to express our deep gratitude to Drs. I. Janda and J. Weiser, both of the Institute of Microbiology of the Czechoslovak Academy of Sciences, for their invaluable help in the editorial work and Mrs. J. Pistorova for patiently retyping all the manu scripts
Download or read book Gene Cloning and Manipulation written by C. J. Howe and published by Cambridge University Press. This book was released on 1995-03-31 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Now fully updated to reflect recent advances, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Written for advanced undergraduate, graduates and scientists who want to use this technology, emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations."--BOOK JACKET.
Download or read book Genetics and the Manipulation of Life written by Craig Holdrege and published by Lindisfarne Books. This book was released on 1996 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative work that challenges our common assumptions about nature and science, this book is for all who want to understand the biological revolution of the late twentieth century. In this clearly written, well-illustrated book, Holdrege describes, using fascinating examples, how living organisms develop and exist within the context of their environments. In an age when we are able to reshape life on earth, this book offers a deeper, more complex vision of nature, one that can help us establish a more conscious and responsible connection to the world around us.
Download or read book An Introduction to Genetic Engineering written by Desmond S. T. Nicholl and published by Cambridge University Press. This book was released on 2008-05-29 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this third edition of his popular undergraduate-level textbook, Des Nicholl recognises that a sound grasp of basic principles is vital in any introduction to genetic engineering. Therefore, the book retains its focus on the fundamental principles used in gene manipulation. It is divided into three sections: Part I provides an introduction to the relevant basic molecular biology; Part II, the methods used to manipulate genes; and Part III, applications of the technology. There is a new chapter devoted to the emerging importance of bioinformatics as a distinct discipline. Other additional features include text boxes, which highlight important aspects of topics discussed, and chapter summaries, which include aims and learning outcomes. These, along with key word listings, concept maps and a glossary, will enable students to tailor their study to suit their own learning styles and ultimately gain a firm grasp of a subject that students traditionally find difficult.
