Download or read book Gene Based Therapies for Pediatric Blood Diseases An Issue of Hematology Oncology Clinics of North America E Book written by Nirali N. Shah and published by Elsevier Health Sciences. This book was released on 2022-07-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Gene Based Therapies for Pediatric Blood Diseases An Issue of Hematology Oncology Clinics of North America written by Sung-Yun Pai, MD and published by Elsevier. This book was released on 2022-08-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Gene Therapy An Issue of Hematology Oncology Clinics of North America E Book written by Daniel E. Bauer and published by Elsevier Health Sciences. This book was released on 2017-09-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Download or read book Pediatric Hematology An Issue of Hematology Oncology Clinics of North America written by Rachael Grace and published by Elsevier Health Sciences. This book was released on 2019-05-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

Download or read book An Update on Pediatric Oncology and Hematology an Issue of Hematology Oncology Clinics of North America written by Max J. Coppes and published by Clinics: Internal Medicine. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue highlights some of the exciting new developments in pediatric oncology and hematology. Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer. Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.

Download or read book Pediatric Hematology an Issue of Hematology Oncology Clinics of North America written by Rachael Grace and published by Elsevier. This book was released on 2019-06-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

Download or read book Pediatric Hematology An Issue of Pediatric Clinics written by Catherine S. Manno and published by Elsevier Health Sciences. This book was released on 2013-12-28 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.

Download or read book Pediatric Hematology Oncology Secrets written by Michael A. Weiner and published by Elsevier Health Sciences. This book was released on 2001-08-31 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Utilizes the proven Secrets Series format to present questions and answers in a convenient, readable, concise manner The text is intended to introduce the reader to the field of pediatric hematology/oncology.Each chapter will emphasize diagnosis, clinical management, therapeutics, and innovative concepts for the future. Highlights of the text include the following chapters: experimental therapeutics, the application of bone marrow and stem cell transplants for pediatric patients, and genetic and molecular diagnostics. There is a section dealing with quality of life and death issues such as supportive care, psychosocial aspects of care of the child with cancer, palliative care, and management of the dying child. Other chapters relate and differentiate disease entities based upon the age of the patient, newborn through adolescent. Each topic covered will discuss diagnosis, clinical management, therapeutics, and innovative concepts for the future. Concise answers that also feature the authors' pearls, tips, memory aids, and "secrets" Bulleted lists and pertinent tables for quick review and reference Succinct chapters written by experts in pediatric hematology and oncology All the most important "need-to-know" questions and answers in the proven format of the highly acclaimed Secrets Series Thorough, highly detailed index

Download or read book Sickle Cell Syndromes An Issue of Hematology Oncology Clinics of North America E Book written by Sophie Lanzkron and published by Elsevier Health Sciences. This book was released on 2022-11-20 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book CAR T Cell An Issue of Hematology Oncology Clinics of North America E Book written by Caron A Jacobson and published by Elsevier Health Sciences. This book was released on 2023-10-12 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Caron A. Jacobson and Parth S. Shah bring their considerable expertise to the topic of CAR T-Cell Therapy. Top experts in the field discuss the multiple ways CAR T-cell therapy can be used to help fight a variety of cancers, such as diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia (ALL). Contains 12 practice-oriented topics including CAR T-cells in aggressive B-cell lymphomas; CAR T-cells in multiple myeloma; CAR T-cells in AML; mechanisms of resistance of CAR T-cell therapy; the role of CAR T-cell therapy in the era of bispecific antibodies; and more. Provides in-depth clinical reviews on CAR T-cell therapy, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book New Drugs for Malignancy An Issue of Hematology Oncology Clinics of North America written by Franco Muggia and published by Elsevier Health Sciences. This book was released on 2012-06-28 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics include: Targeting IGF-1R, Tyrosine Kinase Inhibitors in Lung Cancer, Targeting mTOR, Targeting Hedgehog, Mitotic Inhibitors, Topoisomerase I Inhibitors , and New Strategies and Drugs Inhibiting Folate Pathways.

Download or read book Benign Hematologic Disorders in Children an Issue of Pediatric Clinics of North America written by Michael U. Callaghan and published by Elsevier. This book was released on 2018-04-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue will provide a current update on diagnosis, treatment, and management of children with benig hematological disorders. Dr. Callaghan has put together a comprehensive issue with clinical reviews written by top experts in the field. Articles are devoted to the following topics: Hemophilia; Sickle cell acute chest; Sickle cell drugs; Sickle cell gene therapy; Sickle cell menses and pain; Pediatric DVT; Atypical HUS; von Willebrand Disease; Female bleeding; Functional platelet disorders; Hemolytic anemia; Advocacy in hematology; ITP; and Acquired aplastic anemia. Readers will come away with the current clinical information they need to improve clinical outcomes.

Download or read book Hematological Disorders in Children written by Eiichi Ishii and published by Springer. This book was released on 2017-06-14 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future. Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.

Download or read book Colorectal Cancer An Issue of Hematology Oncology Clinics of North America E Book written by Kimmie Ng and published by Elsevier Health Sciences. This book was released on 2022-05-30 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Kimmie Ng and Benjamin L. Schlechter bring their considerable expertise to the topic of Colorectal Cancer. Despite tremendous progress in the management of this disease, many questions and controversies remain regarding screening, adjuvant therapy for resected colon cancers, targeted therapies and immunotherapy for patients with advanced disease, surgical management, and more. In this issue, top experts in the field address provide clinicians with the tools to individualize management and optimize care for this growing patient population. - Contains 13 relevant, practice-oriented topics including screening for colorectal cancer; hereditary colorectal cancer; disparities in colorectal cancer; microbiome in colorectal cancer; impact of diet and exercise on colorectal cancer; colorectal cancer in younger adults; and more. - Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Central Nervous System Malignancies An Issue of Hematology Oncology Clinics of North America E Book written by David A. Reardon and published by Elsevier Health Sciences. This book was released on 2021-11-24 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editor David A. Reardon? brings his considerable expertise to the topic of Central Nervous System Malignancies. Top experts in the field cover key topics such as CNS Metastases, Leptomeningeal Disease, Neurofibromatoses, Imaging Advances for CNS Tumors, and more. Contains 16 relevant, practice-oriented topics including CNS Tumor Classification: An Update on the Integration of Tumor Genetics; Etiology and Epidemiology of CNS Tumors; The Evolving Role of Neurosurgical Intervention for CNS Tumor ; Update on Radiation Therapy for CNS Tumors; and more. Provides in-depth clinical reviews on CNS Malignancies, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Handbook of Pediatric Hematology and Oncology written by Caroline A. Hastings and published by John Wiley & Sons. This book was released on 2021-02-18 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der überarbeitete Leitfaden für Diagnose, Management und Behandlung von Blutkrankheiten und Krebs bei Kindern. Kinder mit Blutkrankheiten und Krebs sind eine ganz spezifische Gruppe, die besondere Diagnosemaßnahmen und ein spezifisches Management erfordert. Das Handbook of Pediatric Hematology and Oncology stellt Klinikern auf jedem Niveau anhand eines aktuellen Algorithmus praxisorientierte Handlungsanleitungen zur Verfügung. Die aktualisierte dritte Auflage wurde von einem Expertenteam des Children`s Hospital & Research Center Oakland zusammengestellt. - Präsentiert aktuelle Management- und Behandlungsrichtlinien für die meisten bekannten Blutkrankheiten und bösartigen Krebserkrankungen. - Neuester Algorithmus-Ansatz für Diagnose und Management der häufigsten Krankheitsbilder mit Verweisen zur Fachliteratur. - Bietet zum schnellen Nachschlagen Tabellen mit visualisierten Darstellungen der Symptome, Laborergebnissen, Differenzialdiagnosen und beinhaltet Behandlungsempfehlungen. - Zeigt mittels Fallstudien die verschiedenen hämatologischen und onkologischen Aspekte, u. a. hämolytische Anämie, Sichelzellenkrankheit, Hämophilie, Neuroblastom, weiches und hartes Sarkom. -Enthält eine nützliche Arzneimittelliste und Informationen zu chemotherapeutischen Wirkstoffen, Dosierung, Handlungsmechanismen, Schwangerschaft, Indikationen und Nebenwirkungen. - Behandelt Transfusionsmedizin, Stammzellentransplantation, Management zentraler Venenkatheter, Schmerzbehandlung, onkologische Notfälle und Grundlagen der Chemotherapie. Aufgrund seiner Praxisorientierung und des handlichen Formats ist die 3. Auflage des Handbook of Pediatric Hematology and Oncology eine unschätzbare Quelle für Medizinstudenten, Praktikanten, Patienten, Fach- und Pflegepersonal in der pädiatrischen Hämatologie und Onkologie, Kinderärzte und Einsteiger in das Fachgebiet der Hämatologie und Onkologie.

Download or read book Pancreatic Cancer An Issue of Hematology Oncology Clinics of North America E Book written by Matthew B. Yurgelun and published by Elsevier Health Sciences. This book was released on 2022-10-22 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editors Drs. Matthew B. Yurgelun and Douglas A. Rubinson bring their considerable expertise to the topic of Pancreatic Cancer. Top experts in the field cover key topics such as pancreatic adenocarcinoma: trends in epidemiology, risk factors, and outcomes; decision making regarding perioperative therapy in individuals with localized pancreatic adenocarcinoma; the evolving role of radiotherapy in the management of individuals with pancreatic adenocarcinoma; and more. - Contains 14 relevant, practice-oriented topics including diabetes, cachexia, sarcopenia, and metabolic factors in individuals with pancreatic adenocarcinoma; PARP inhibitors and other novel therapeutics in pancreatic adenocarcinoma; screening and surveillance for pancreatic adenocarcinoma in high-risk individuals; germline testing for individuals with pancreatic adenocarcinoma and novel genetic risk factors; and more. - Provides in-depth clinical reviews on pancreatic cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.