Download or read book GENATLAS written by Jean Frézal and published by John Libbey Eurotext. This book was released on 1991 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Analysing Gene Expression written by Stefan Lorkowski and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying particular attention to the automated, high-throughput processing demanded by the biotech industry. Completely up to date, the book covers such ground-breaking methods such as DNA microarrays, serial analysis of gene expression, differential display, and identification of open reading frame expressed sequence tags. All the methods and necessary equipment are presented visually in more than 300 mainly colour illustrations to assist their step-by-step reproduction in your laboratory. Each chapter is rounded off with its own set of extensive references that provide access to detailed experimental protocols. In short, the bible of analysing gene expression.
Download or read book Bioinformatics written by Zoé Lacroix and published by Elsevier. This book was released on 2003-09-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life science data integration and interoperability is one of the most challenging problems facing bioinformatics today. In the current age of the life sciences, investigators have to interpret many types of information from a variety of sources: lab instruments, public databases, gene expression profiles, raw sequence traces, single nucleotide polymorphisms, chemical screening data, proteomic data, putative metabolic pathway models, and many others. Unfortunately, scientists are not currently able to easily identify and access this information because of the variety of semantics, interfaces, and data formats used by the underlying data sources. Bioinformatics: Managing Scientific Data tackles this challenge head-on by discussing the current approaches and variety of systems available to help bioinformaticians with this increasingly complex issue. The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable. * Provides a clear overview of the state-of-the-art in data integration and interoperability in genomics, highlighting a variety of systems and giving insight into the strengths and weaknesses of their different approaches. * Discusses shared vocabulary, design issues, complexity of use cases, and the difficulties of transferring existing data management approaches to bioinformatics systems, which serves to connect computer and life scientists. * Written by the primary contributors of eight reputable bioinformatics systems in academia and industry including: BioKris, TAMBIS, K2, GeneExpress, P/FDM, MBM, SDSC, SRS, and DiscoveryLink.
Download or read book Genetic Databases written by and published by Academic Press. This book was released on 1999-09-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer access is the only way to retrieve up-to-date sequences and this book shows researchers puzzled by the maze of URLs, sites, and searches how to use internet technology to find and analyze genetic data. The book describes the different types of databases, how to use a specific database to find a sequence that you need, and how to analyze the data to compare it with your own work. The content also covers sequence phenotype, mutation, and genetic linkage databases; simple repetitive DNA sequences; gene feature identification; and prediction of structure and function of proteins from sequence information. This book will be invaluable to those starting a career in life sciences research as well as to established researchers wishing to make full use of available resources. Describes a wide range of databases: DNA, RNA, protein, pathways, and gene expression Enables readers to access the information they need from databases on the web Includes a directory of URLs for easy reference Invaluable for those starting a career in life sciences research and also for established researchers wishing to make full use of available resources
Download or read book The General Genetic Catastrophe written by Nils K. Oeijord and published by iUniverse. This book was released on 2011-02-24 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nils K. Oeijords research since 1999 shows that we have a worldwide general genetic catastrophe (GGC) due to general local and global manmade mutagenic pollution. The GGC began in the 1700s, increased in the 1800s, and exploded in the 1900s. The HIGH and INCREASING prevalence and the HIGH and INCREASING incidence of gene damage and genetic diseases all over the world logically prove the existence of the GGC. Nils K. Oeijord is a science writer, a former researcher (plant production), a former assistant professor (mathematics), and a former science and mathematics lecturer (high school). He is the discoverer of the general genetic catastrophe, and has earned a place in Whos Who in the World (28th Edition), in Great Minds of the 21st Century (5th Edition), and in 2000 Outstanding Intellectuals of the 21st Century (2011 Edition).
Download or read book Toxicogenomics written by Hisham K. Hamadeh and published by John Wiley & Sons. This book was released on 2004-09-06 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicogenomics: Principles and Applications fills the need for a single, thorough text on the key breakthrough technologies in genomics, proteomics, metabolomics, and bioinformatics, and their applications to toxicology research. The first section following a general introduction is on genomics and toxicogenomics, and qPCR. The next sections are toxicoproteomics and metabolomics. The final section covers bioinformatics aspects, from databases to data integration strategies. A practical resource for specialists and non-specialists alike, this book includes numerous illustrations that support the textual explanations. It offers practical guidance to investigators wishing to pursue this line of research, and lists key relevant software and Internet resources.
Download or read book Family Medicine written by A.K. David and published by Springer Science & Business Media. This book was released on 2013-05-13 with total page 1199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Family Medicine: Principles and Practice is a comprehensive reference text providing clear guidelines for diagnosing and managing acute and chronic illnesses regularly seen in family practice. The sixth edition will follow the format successfully established with the fourth edition. In addition, it will include new chapters on: Herbal Medicine, Hospitalist Medicine, Telemedicine, Evidence-Based Medicine, Osteopathic Medicine, Effective Office Management. Also, a whole new section on The Future of Family Medicine will be added. All chapters will be completely updated and with new clinical guidelines and references. Websites will be included in the references as well.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diagnostic Molecular Pathology in Practice written by Iris Schrijver and published by Springer Science & Business Media. This book was released on 2011-09-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.
Download or read book Prostate Cancer written by Leland W. K. Chung and published by Springer Science & Business Media. This book was released on 2007-11-10 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.
Download or read book EHealth Beyond the Horizon written by European Federation for Medical Informatics. International Congress and published by IOS Press. This book was released on 2008 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of the MIE 2008 conference theme - eHealth Beyond the Horizon - highlights the expectations for the future of ehealth and raises the question: What sort of developments in ehealth services can we imagine emerging above the horizon in the years to come? EHealth Beyond the Horizon contains a good number of high-quality papers giving different perspectives of this future, some of them already available today in picot scale, some of them outlined in visions. The second part of the theme - Get IT There - has triggered a large number of papers describing how to create, evaluate, adjust and deliver products and deploy services in healthcare organizations for the necessary information technology as a basis for the ehealth applications that are essential in order to respond to the challenges of the health systems. The papers in the proceedings are grouped by themes according to the submission categories and the supplied keywords. As the last theme, three doctoral students from different areas of medical informatics were selected to present and discuss their research under the guidance of a panel of distinguished research faculties.
Download or read book Molecular Genetic Testing in Surgical Pathology written by John D. Pfeifer and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts from Washington University School of Medicine, this text is a thorough review of the specific molecular genetic techniques that can provide diagnostically useful molecular genetic information on tissue samples—including cytogenetics, fluorescence in situ hybridization (FISH), PCR, electrophoresis and hybridization analysis, DNA sequence analysis, and microarrays. The first part of the book describes each technique, indicates its advantages, disadvantages, capabilities, and limitations, and systematically addresses sensitivity and specificity issues. Subsequent chapters, organized by organ system, detail the specific applications of these tests in surgical pathology. More than 150 full-color and black-and-white illustrations complement the text.
Download or read book Pharmacogenomics written by Werner Kalow and published by CRC Press. This book was released on 2001-05-08 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."
Download or read book Hormonal Signaling in Biology and Medicine written by Gerald Litwack and published by Academic Press. This book was released on 2019-10-24 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology covers the endocrine secretions produced by every organ. This extensive collection of knowledge is organized by tissue, addressing how certain hormones are synthesized in multiple tissues, along with their structure, function and pathways, which are very applicable for researchers in drug design who need to focus on a specific step along the pathway. This is a must have reference for researchers in endocrinology and practicing endocrinologists, but it is also ideal for biochemists, pharmacologists, biologists and students. Serves as a valuable desk reference for researchers Provides information on the structure of a given hormone, its receptor(s), and the pathways that become activated Includes extensive citations to the literature that will enable the reader to dig more deeply into the effects of a given hormone
Download or read book Mitochondrial Diseases written by Eylem Taskin and published by BoD – Books on Demand. This book was released on 2018-08-29 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.
