Download or read book Gastric Cancer Prewarning and Early Diagnosis System written by Daxiang Cui and published by Springer. This book was released on 2017-06-21 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores recent developments in the application of nanotechnology in the early detection of gastric cancer. It discusses various aspects, such as screening for gastric cancer-associated biomarkers; establishing new ultrasensitive detection methods based on nanoparticle labeling and nanoeffects; developing a new generation of nanodevices for high-throughput examination of serum and breath biomarkers; developing multifunctional nanoprobes for targeted imaging and simultaneous therapy of gastric cancer; evaluating the biosafety of multifunctional nanoprobes; and the establishment of a pre-warning and early diagnosis system. It also presents clinical applications and prospects. The book provides a valuable reference for researchers in nanomedicine and clinicians involved in gastric cancer and radiology.
Download or read book Advances in Nanotheranostics II written by Zhifei Dai and published by Springer. This book was released on 2016-01-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.
Download or read book Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers written by Ganji Purnachandra Nagaraju and published by Springer Nature. This book was released on 2020-10-07 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) malignancies account for a large portion of cancers worldwide. Although incidence of esophageal, gastric, and colorectal cancers has decreased in recent years, pancreatic and liver cancer have increased. The mainstay of GI cancer therapy is chemoradiation and surgery. Despite significant medical advancements, diagnosis and therapy for GI cancers remain challenging due to tumor cell resistance to chemoradiotherapy. The tumor’s increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells. This leads to tumor chemoresistance. To circumvent these difficulties, drug therapy targeting the tumor’s specific microenvironment and the additive anticancer effect of phytochemicals can allow for more effective treatment. This volume will be the first on the market on the topic of phytochemicals and their effect on the tumor microenvironment (TME). TME is an emerging area of research and the book will be a welcome introductory addition to the field.
Download or read book Handbook of Nanomaterials for Cancer Theranostics written by Joao Conde and published by Elsevier. This book was released on 2018-06-27 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments
Download or read book Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers written by Pallaval Veera Bramhachari and published by Springer Nature. This book was released on 2020-07-21 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancer treatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.
Download or read book Genetic and proteomic biomarkers in solid tumor detection and treatment written by Jitian Li and published by Frontiers Media SA. This book was released on 2023-06-07 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gastric Carcinoma written by Daniela Lazar and published by BoD – Books on Demand. This book was released on 2013-01-23 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer is the second most common cause of cancer-related death in the world. There are no screening tests available for its diagnosis, therefore patients usually presents in late stages, associated with poor prognosis. Currently, many efforts are made toward new advances in the treatment strategies. The book makes an insight into the assessment of premalignant lesions, current management of early gastric cancer, risk and protective factors in gastric carcinogenesis. "Gastric cancer" provides a detailed description of the morphologic classification, molecular changes and epigenetic alterations of this tumor. The book describes the role of different diagnostic tools in the preoperative assessment of patients and the most important factors contributing to the prognosis. Moreover, it describes the current surgical and chemotherapeutic options for gastric neoplasm. This publication may open new and interesting gates for further research concerning carcinogenesis, genetic and epigenetic alterations, signaling pathways, H. pylori infection, the discovery of protective factors against gastric cancer and of revolutionary therapies of this tumor.
Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Download or read book Independent Inquiry into care provided by Mid Staffordshire NHS Foundation Trust January 2005 March 2009 written by Mid Staffordshire NHS Foundation Trust Inquiry and published by The Stationery Office. This book was released on 2010-02-24 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concerns about mortality and the standard of care provided at the Mid Staffordshire NHS Foundation Trust resulted in an investigation by the Healthcare Commission which published a highly critical report in March 2009, followed by two reviews commissioned by the Department of Health. These investigations gave rise to widespread public concern and a loss of confidence in the Trust, its services and management. This Inquiry was set up primarily to give those most affected by poor care an opportunity to tell their stories and to ensure that the lessons learned were fully taken into account in the rebuilding of confidence in the Trust. The evidence received about the patient experience covered many areas of basic nursing and medical care, communication and discharge management. The culture of the Trust was not conducive to providing good care for patients or providing a supportive working environment for staff due to: attitudes of patients and staff; bullying; target-driven priorities; disengagement from management; low staff morale; isolation from the wider NHS community; lack of openness; acceptance of poor standards of conduct; reliance on external assessments; denial. The report also looks at the management of significant issues - ward reconfiguration, finance, staff cuts - governance, staff review, the Board, mortality statistics and external organisations. Major themes identified by the Inquiry are: focus on process not outcomes; failure to listen to complaints; insufficient attention to maintenance of professional standards; lack of support for staff; failure to meet the challenge of care for the elderly; lack of transparency; disregard of the significance of mortality statistics.
Download or read book AI and Learning Systems written by Konstantinos Kyprianidis and published by BoD – Books on Demand. This book was released on 2021-02-17 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last few years, interest in the industrial applications of AI and learning systems has surged. This book covers the recent developments and provides a broad perspective of the key challenges that characterize the field of Industry 4.0 with a focus on applications of AI. The target audience for this book includes engineers involved in automation system design, operational planning, and decision support. Computer science practitioners and industrial automation platform developers will also benefit from the timely and accurate information provided in this work. The book is organized into two main sections comprising 12 chapters overall: •Digital Platforms and Learning Systems •Industrial Applications of AI
Download or read book The Work of Professional Football written by Martin Roderick and published by Routledge. This book was released on 2006-09-27 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: A long-term study providing rare insights into the precarious career and ordinary working culture of professional footballers. Away from the celebrity-obsessed media gaze, the work of a professional footballer is rarely glamorous and for most players a career in football is insecure and short-lived. A former professional, Martin Roderick’s familiarity with the world of football is the foundation for this privileged research into a world that is typically closed to the public gaze and ignored by media reportage and academic research which prefers to focus on a small, unrepresentative group of elite players. Key themes explored within the text include: the culture of work in professional football the changing identity, orientation and expectations of players during their careers the fragile and uncertain nature of professional sport careers the performance and dramatic aspects of a career under public scrutiny the role of relationships with managers, owners, support staff and partners players' responses to the insecurities inherent in professional football such as injury, ageing, performance and transfer. The text deals with a wide range of issues of interest to sports students and academics, particularly those with a focus on the sociology of sport but also including sport development, sport management and coaching studies. The text will also be of interest to researchers in the fields of careers, industrial relations and the sociology of work.
Download or read book Complex Intelligent and Software Intensive Systems written by Leonard Barolli and published by Springer Nature. This book was released on 2021-06-29 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes the proceedings of the 15th International Conference on Complex, Intelligent, and Software Intensive Systems, which took place in Asan, Korea, on July 1–3, 2021. Software intensive systems are systems, which heavily interact with other systems, sensors, actuators, devices, and other software systems and users. More and more domains are involved with software intensive systems, e.g., automotive, telecommunication systems, embedded systems in general, industrial automation systems, and business applications. Moreover, the outcome of web services delivers a new platform for enabling software intensive systems. Complex systems research is focused on the overall understanding of systems rather than its components. Complex systems are very much characterized by the changing environments in which they act by their multiple internal and external interactions. They evolve and adapt through internal and external dynamic interactions. The development of intelligent systems and agents, which is each time more characterized by the use of ontologies and their logical foundations build a fruitful impulse for both software intensive systems and complex systems. Recent research in the field of intelligent systems, robotics, neuroscience, artificial intelligence, and cognitive sciences is very important factor for the future development and innovation of software intensive and complex systems. The aim of the book is to deliver a platform of scientific interaction between the three interwoven challenging areas of research and development of future ICT-enabled applications: Software intensive systems, complex systems, and intelligent systems.
Download or read book Analgesia Anaesthesia and Pregnancy written by Steve Yentis and published by Cambridge University Press. This book was released on 2012-11-15 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analgesia, Anaesthesia and Pregnancy focuses on pre-empting problems and maximising quality of care. Every chapter of this well-established practical guide has been completely updated and revised. All aspects of obstetric medicine relevant to the anaesthetist are covered, from pre-pregnancy management to conception, throughout pregnancy, to postnatal care. The authors have identified over 150 potential complications, each covered in two parts: 'problems/special considerations' and 'management options', with key points prominently displayed for quick reference. A section on organisational aspects such as record keeping, training protocols and guidelines makes this an important resource for any labour ward or hospital dealing with pregnant women. Presented in a clear, structured format, this practical summary will be invaluable to any anaesthetist encountering obstetric patients, whether they are a practiced consultant or still in training. It will also be useful for obstetricians, neonatologists, midwives, nurses and operating department practitioners wishing to extend or update their knowledge.
Download or read book Oxford Desk Reference Major Trauma written by Jason Smith and published by Oxford University Press. This book was released on 2010-11-11 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Text covers all the main areas of trauma care necessary for the trauma specialist in the 21st century.
Download or read book Each Woman s Menopause An Evidence Based Resource written by Patricia Geraghty and published by Springer Nature. This book was released on 2021-12-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to meet the needs of nurse practitioners, other advanced practice nurses, and allied health professionals working in women’s health, primary care, and other specialties. The multiple roles the clinician embraces in menopause management include that of direct caregiver, manager of therapeutics, educator, and interdisciplinary team member or leader. This book provides updated, evidence based information on the menopause transition from the late reproductive stage to post-menopause to optimize the interaction of the clinician and the individual woman in each of those roles. Women’s lived experiences of menopause and women’s concerns regarding both the menopause transition and the choice of care options are included as critical components of shared therapy decisions. The review of natural menopause physiology and the variability of menopause symptoms are inclusive of diverse women and diverse trajectories. The impact of menopause on chronic disease, sleep, weight and nutrition, mood and cognition, urogenital health and sexuality, as well as vasomotor symptoms are each developed as individual topics by experts in those fields. Evidence based management using hormonal and non-hormonal options, and life-style and other complementary interventions are discussed with the most updated advantages and disadvantages of each treatment option. Consistent with advanced practice nursing theory, the approach is whole patient focused.
Download or read book Take Control of Your Cancer Risk written by John Whyte, MD, MPH and published by Harper Horizon. This book was released on 2021-10-05 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Something everyone has the power to do is reduce your cancer risk, and this book will show you just how easy it is to do it. Each year, over a million people in the United States alone hear the words no one ever wants to hear: You have cancer. But what if there was a way for fewer people to hear these words? One of the biggest myths regarding cancer is that it’s mostly genetic - meaning that you have no control over whether you get it. While genetics do have an impact, the truth is that your lifestyle and environment play the major role. Physician and Chief Medical Offer of WebMD John Whyte, MD, MPH, shares straightforward information and equips you with strategies to help you on a journey to better health. In Take Control of Your Cancer Risk, Dr. Whyte provides helpful tips including: assessing your cancer risk knowing which screenings you need, and when learning the role food, exercise, and sleep play understanding the relationship between stress and cancer Take Control of Your Cancer Risk is filled with practical advice that empowers you to really take control of our health.
Download or read book Anticancer Research written by and published by . This book was released on 1981 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt:
