Download or read book Gangliosides and Neuronal Plasticity written by G. Tettamanti and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the Proceedings of the Meeting "Neuronal plasticity and gangliosides" which was held at Mantova, Italy, on May 29-31, 1985, as a satellite to the Tenth Meeting of the International Society for Neurochemistry, (Riva del Garda, Italy, May 19-24,1985). The Symposium took place in the "Teatro Bibiena", one of the oldest and most beautiful theatres in Italy, known for having been the place for some of the very first performances of W .A. Mozart. The number of registered participants in the Meeting was about 180 including 40 accor:Qpanying persons. The persons invited as Speakers or Chairmen of Colloquia and Workshops were 48. Eighteen countries were represented with the largest contingent coming from Italy, followed by Federal Republic of Germany, The United States, France and Great Britain. The Meeting was based on Colloquia, Workshops, Round Tables and Poster Sessions, with a total of 42 Lectures and 32 Poster presentations.
Download or read book Gangliosides and Modulation of Neuronal Functions written by Hinrich Rahmann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NATO Advanced Research Workshop on "Gangliosides and Modu lation of Neuronal Functions" was held at the University of Stutt gart-Hohenheim, Federal Republic of Germany, on October 20 - 24, 1986. About 70 participants from 10 countries presented papers on a wide range of topics all concerning the ganglioside theme. The content of the workshop consisted of the following chap ters: (1) Fundamentals for research on function of gangliosides; (2) Brain ganglioside metabolism; (3) Cell specific distribution and differentiation-related ex pression of brain gangliosides; (4) Gangliosides and neuronal plasticity; (5) Bio-medical potential of exogenous ganglioside application on neuronal function; and (6) Critical assessments on aspects of ganglioside therapy. The aim of the workshop was to sum up and discuss the present knowledge in the respective fields. Despite intensive research on gangliosides ever since Ernst Klenk discovered them in 1936, the biological function of. these amphiphilic, "sphinx-like" glycosphingo lipids remains elusive. Over the past few years, several thousands of articles on gangliosides have been published demonstrating very special properties of these glycolipids and their possible in volvement in diverse biological phenomena. As far as we know up to the present time, these properties may be due to particular physico-chemical attributes of these compounds, especially in com bination with calcium. The results obtained so far have shed light not only on pos sible functional roles of gangliosides with regard to cellular induction and organization, but have also unexpectedly opened up VI a whole new field of therapeutic applications for these compounds.
Download or read book Neuronal Plasticity and Trophic Factors written by Giovanni Biggio and published by . This book was released on 1988 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurobiology of Gangliosides written by Alfredo Gorio and published by . This book was released on 1985 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Post Lesion Neural Plasticity written by Hans Flohr and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural networks are not rigidly wired but rather highly plastic structures, the functional architecture of which can be actively reorganized in response to external or internal events. Lesions of such networks induce plastic processes which in time may lead to a recovery of the initially disrupted function. This type of neural plasticity is the main focus of the book, which presents a broad spectrum of experimental paradigms for lesion-induced plasticity as in the spinal cord, the vestibular, oculomotor, visual and olfactory system, the cerebellum and the cerebral cortex, including recent methodological developments. Concepts and perspectives in understanding neural plasticity are reported in reviews and original research reports and are thoroughly discussed.
Download or read book Neuronal Plasticity and Memory Formation written by Cosimo Ajmone Marsan and published by . This book was released on 1982 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Lipids in Synaptic Function and Neurological Disease written by Jacques Fantini and published by Academic Press. This book was released on 2015-05-12 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders. Written to provide a "hands-on" approach for readers Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings Step-by-step guide to memorize and draw lipid structures Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique
Download or read book GM3 Signaling written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2020-07-10 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field.
Download or read book The Chemistry of Behavior written by Stanislav Reinis and published by Springer. This book was released on 1982-09-30 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses a particular aspect of brain function, that of storage and retrieval of memory of past experience, in terms of neuronal plasticity. In discussing this aspect of brain functions, however, it discusses brain mecha nisms in their wider sense as well. Clearly, the central nervous system is a highly interconnected system from all points of view, and it would not be possible to understand function in terms of only a single event or only a sin gle neurotransmitter. This is true for any biochemical activity that accompanies neuronal functional activity and accompanies behavior. The authors have commendably recognized this complexity, and recognize still more the need to present information in a compact and uniform manner in spite of the tremendous expansion of our knowledge in recent years. It is a somewhat easier task to gather a set of authors and record their results for a multiauthor symposium, but it is a most admirable endeavor for two authors to summarize a field that encompasses subjects such as transmission barri ers, lipids, proteins, energy, hormones, to name a few that this book covers so well in a compact manner, and in such depth as well. Metabolism and func tion cannot really be understood without understanding structural factors, changes in membrane properties, and changes in metabolism.
Download or read book Synaptic Plasticity in the Hippocampus written by Helmut L. Haas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.
Download or read book The Sugar Code written by Hans-Joachim Gabius and published by John Wiley & Sons. This book was released on 2011-09-19 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE
Download or read book Brain Plasticity Learning and Memory written by B. E. Will and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the contributions presented at a conference held from August 30 to September 1, 1984 at the Universite Louis Pasteur, Strasbourg, France. This meeting was organized under the joint auspices of the European Brain and Behaviour Society (EBBS) and the Societe Fran~aise pour 1 'Etude du Comportement Animal (SFECA). The objective of this meeting was to bring together an international group of participants to evaluate and to report on recent research in three broad and overlapping fields within the general theme of the relationships between brain plasticity and learning and memory. These three fields are "developmental plasticity" "adaptive plasticity" and "restorative plas tici ty." Al though the boundaries between these fie Ids are a rna t ter of debate (see Introduction), they have been retained as the major sections of this volume, the arrangement of which roughly parallels that of the meeting. We believe and very much hope that the contents of this volume convey an internal consistency despite the diversity of the material presented.
Download or read book Biochemical Basis of Functional Neuroteratology written by and published by Elsevier. This book was released on 1988-07-01 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Basis of Functional Neuroteratology
Download or read book Biochemistry of Brain written by Sudhir Kumar and published by Pergamon. This book was released on 1980 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase ...
Download or read book Neural Development and Regeneration written by A. Gorio and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data of all relevant aspects of neuronal cell growth and differentiation are presented in this volume. Regulation of expression, storage and release of nerve growth factors, receptor control and the cellular responses to growth factors are comprehensively discussed. Treated are also influences of various neurotransmitters on neuronal morphogenesis and new results of interactions of cells and mediators of the immune, endocrine and nervous system. Special emphasis is given to those factors regulating regeneration and nerve spreading after injuries of the nerve tissue.
Download or read book Machinery of the Mind written by JOHN and published by Springer Science & Business Media. This book was released on 1990-01-01 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the spring of 1987, I was in Havana, Cuba, where I was participating in planning a large-scale longitudinal study of the neurophysiological, neurochemical, and behavioral characteristics of cohorts of patients with cerebrovascular disease, depression, senile dementia, schizophrenia, or learning disabilities; and also part of this study were their first-degree blood relatives. This study was the outgrowth of a long-term project on the practical application of computer methods for the evaluation of brain electrical activity related to anatomical integrity, maturational development, and sensory, perceptual;·-and cognitive processes, especially in chil dren. For many years, that project had been supported by the United Nations Development Program (UNDP), the National Scientific Research Center of Cuba (CNIC), and the Ministries of Public Health and of Education of Cuba. Since its inception, I had served as a technical advisor to the UNDP project. When the project began, I became acquainted with Dr. Jose M. Miyar Barrueco, who was at that time the Rector of the Medical School of the University of Havana. Because of his keen interest in the new computer technology and its potential utility in developing countries, we met from time to time during my visits. These occasional meetings continued after he became Secretary of the Cuban Council of State, so that he could remain apprised of progress and problems with which he might help.
Download or read book Biological Function of Gangliosides written by Nobel Symposium and published by Elsevier. This book was released on 1994-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial role of gangliosides, also in therapeutic administration. There is a section on the role of gangliosides in neuronal differentiation and development and their receptor functions and cell surface activities. This excellent addition to the renowned Progress in Brain Research series also contains an invaluable plenary lecture on molecular basis of cell adhesion by Nobel prizewinner Gerald Edelman.
