Download or read book Fungal Siderophores written by Kalyani Dhusia and published by Springer Nature. This book was released on 2021-02-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades, it has been realized through research that fungal siderophores epitomize the uptake of iron as well as other essential elements like zinc, magnesium, copper, nickel and arsenic. Understanding the chemical structures of different fungal siderophores and the membrane receptors involved in uptake of mineral ions has opened new areas for research. In this edited volume, recent research is presented on fungal siderophores in one comprehensive volume to provide researchers a strong base for future research. Siderophores are the low molecular weight, high affinity iron-chelating compounds produced by bacteria and fungi. They are responsible for transporting iron across the cell membrane. Fungi produce a range of hydroxamate siderophores involved in the uptake of essential elements in almost all microorganisms and plants. In recent years, siderophores have been used in molecular imaging applications to visualize and understand cellular functions, which thus provide an opportunity to identify new drug targets. Therefore, knowledge of fungal siderophores has become vital in current research. Siderophores have received much attention in recent years because of their potential roles and applications in various research areas. Their significance in these applications is because siderophores have the ability to bind a variety of metals in addition to iron, and they have a wide range of chemical structures and specific properties. For instance, siderophores function as biocontrols, biosensors, and bioremediation and chelation agents, in addition to their important role in weathering soil minerals and enhancing plant growth. This book focuses on siderophores with the following significant points. It discusses leading, state-of-the-art research in all possible areas on fungal siderophores. The contributors are well-known and recognized authorities in the field of fungal siderophores. It discusses a projection of practical applications of fungal siderophores in various domains. This is the first book exclusively on fungal siderophores. In this comprehensive, edited volume, we show leading research on fungal siderophores and provide the most recent knowledge of researchers' work on siderophores. This book presents in-depth knowledge on siderophores to researchers working in areas of health sciences, microbiology, plant sciences, biotechnology, and bioinformatics.
Download or read book Fungal Siderophores written by Kalyani Dhusia and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades, it has been realized through research that fungal siderophores epitomize the uptake of iron as well as other essential elements like zinc, magnesium, copper, nickel and arsenic. Understanding the chemical structures of different fungal siderophores and the membrane receptors involved in uptake of mineral ions has opened new areas for research. In this edited volume, recent research is presented on fungal siderophores in one comprehensive volume to provide researchers a strong base for future research. Siderophores are the low molecular weight, high affinity iron-chelating compounds produced by bacteria and fungi. They are responsible for transporting iron across the cell membrane. Fungi produce a range of hydroxamate siderophores involved in the uptake of essential elements in almost all microorganisms and plants. In recent years, siderophores have been used in molecular imaging applications to visualize and understand cellular functions, which thus provide an opportunity to identify new drug targets. Therefore, knowledge of fungal siderophores has become vital in current research. Siderophores have received much attention in recent years because of their potential roles and applications in various research areas. Their significance in these applications is because siderophores have the ability to bind a variety of metals in addition to iron, and they have a wide range of chemical structures and specific properties. For instance, siderophores function as biocontrols, biosensors, and bioremediation and chelation agents, in addition to their important role in weathering soil minerals and enhancing plant growth. This book focuses on siderophores with the following significant points. It discusses leading, state-of-the-art research in all possible areas on fungal siderophores. The contributors are well-known and recognized authorities in the field of fungal siderophores. It discusses a projection of practical applications of fungal siderophores in various domains. This is the first book exclusively on fungal siderophores. In this comprehensive, edited volume, we show leading research on fungal siderophores and provide the most recent knowledge of researchers' work on siderophores. This book presents in-depth knowledge on siderophores to researchers working in areas of health sciences, microbiology, plant sciences, biotechnology, and bioinformatics.
Download or read book Microbial Siderophores written by Ajit Varma and published by Springer Science & Business Media. This book was released on 2007-07-04 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to low iron availability in the environment most microorganisms synthesize iron chelators, called siderophores. Bacteria and fungi produce a broad range of structurally diverse siderophores, all of which show a very high affinity for ferric ions. This book presents an up-to-date overview of the chemistry, biology and biotechnology of these iron chelators. Coverage ranges from an introductory chapter to siderotyping to applications in human and plant health.
Download or read book Metal Ions in Fungi written by Gunther Winkelmann and published by CRC Press. This book was released on 2020-08-26 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the latest advances in the study of the intracellular fate and transport of metal ions in fungi, emphasizing the mechanisms that regulate cellular concentration. The book explains the expanding relationship between molecular genetics and inorganic biochemistry.
Download or read book Microbial Siderophores written by Ajit Varma and published by Springer. This book was released on 2009-09-02 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to low iron availability in the environment most microorganisms synthesize iron chelators, called siderophores. Bacteria and fungi produce a broad range of structurally diverse siderophores, all of which show a very high affinity for ferric ions. This book presents an up-to-date overview of the chemistry, biology and biotechnology of these iron chelators. Coverage ranges from an introductory chapter to siderotyping to applications in human and plant health.
Download or read book Damp Indoor Spaces and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-10-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.
Download or read book Oxford Textbook of Medical Mycology written by Christopher C. Kibbler and published by Oxford University Press. This book was released on 2017-12-14 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.
Download or read book Nematode Trapping Fungi written by Ke-Qin Zhang and published by Springer Science & Business. This book was released on 2014-04-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: These chapters provide up-to-date information on nematophagous fungi, particularly those of the Orbiliaceae in Ascomycota, whose asexual states produce nematode-trapping devices. The authors consider fungal-nematode interactions, fossil fungi, the biodiversity, ecology and geographical distribution of nematode-trapping fungi, and their potential use in biocontrol of nematodes, all in detail. Nematode-trapping fungi with adhesive or mechanical hyphal traps are the main focus of this book which begins with an overview of the data on nematode-trapping fungi, including their taxonomy, phylogeny and evolution. Subsequent chapters expand upon the methods and techniques used to study these fascinating fungi. Keys for genera of Arthrobotrys, Drechslerella and Dactylellina, which include all reported species of predatory orbiliaceous fungi are presented and numerous species from these genera are morphologically described and illustrated. The ecology of nematode-trapping fungi is expertly presented: their occurrence and habitats, their geographical and seasonal distribution and the effects of soil conditions and nematode density on their distribution all feature amongst the relevant themes. Further chapters examine the use of nematode-trapping fungi in biological control and the authors consider nematicidal activities in detail, exploring the many compounds from fungi that feature in nematicidal activities and of course useful paths for further study on this topic. This is a highly informative and carefully presented book, providing scientific insight for scholars with an interest in fungi and in biological control of nematodes.
Download or read book Iron Nutrition in Plants and Rhizospheric Microorganisms written by Larry L. Barton and published by Springer Science & Business Media. This book was released on 2007-08-20 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review on the status of iron nutrition in plants. It contains updated reviews of most relevant issues involving Fe in plants and combines research on molecular biology with physiological studies of plant-iron nutrition. It also covers molecular aspects of iron uptake and storage in Arabidopsis and transmembrane movement and translocation of iron in plants. This book should serve to stimulate continued exploration in the field.
Download or read book Fungal Biology written by J. W. Deacon and published by John Wiley & Sons. This book was released on 2013-04-29 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Visit the accompanying website from the author at www.blackwellpublishing.com/deacon. Fungal Biology is the fully updated new edition of this undergraduate text, covering all major areas of fungal biology and providing insights into many topical areas. Provides insights into many topical areas such as fungal ultrastructure and the mechanisms of fungal growth, important fungal metabolites and the molecular techniques used to study fungal populations. Focuses on the interactions of fungi that form the basis for developing biological control agents, with several commercial examples of the control of insect pests and plant diseases. Emphasises the functional biology of fungi, with examples from recent research. Includes a clear illustrative account of the features and significance of the main fungal groups.
Download or read book The Importance of Secreted Siderophores in Diagnosis and Virulence of Invasive Fungal Infections written by Cassandra Sariya Carroll and published by . This book was released on 2018 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron acquisition is essential for growth. In pathogenic Mucorales fungi, reductive iron assimilation contributes to virulence whereas in Aspergillus fumigatus, siderophore biosynthesis is essential for pathogenesis. The overall aim of my research was to investigate the synthesis and diagnostic importance of siderophores of these two groups of pathogenic fungi. Biosynthesis of select siderophores has been shown to occur using non-ribosomal peptide synthetase (NRPS)-independent siderophore (NIS) synthetases. I used crystal structures to compare NIS enzymes involved in the biosynthesis of 8 siderophores. I proposed a new class of Type C' synthetases, responsible for dimerization/macrocyclization of more complex and substituted intermediates. I also demonstrated that NIS enzymes are predicted to be present in all Domains of life. I identified an NIS homolog in the fungal pathogen, Rhizopus delemar, and confirmed that the enzyme (Rfs) was responsible for synthesis of the polycarboxylate siderophore, rhizoferrin. Rfs kinetic parameters were comparable to bacterial NIS enzymes. Rfs used diaminobutane, ornithine, diaminopentane and diaminopropane as nucleophiles. Site-directed mutagenesis showed that H484 is essential, and that L544 may govern nucleophile specificity. These data provide the first characterization of a fungal NIS enzyme. We identified an uncharacterized siderophore, termed Band 4, in Aspergillus terreus. Band 4 did not restore growth of a sidA mutant of A. fumigatus suggesting that Band 4 is structurally unrelated to A. fumigatus hydroxamate siderophores. Studies of an A. terreus sidA mutant indicated that biosynthesis of Band 4 is not co-regulated with hydroxamate siderophores. An iron-regulated NIS homologue (AtNIS) was identified and recombinant AtNIS was generated. rAtNIS can be used to confirm its involvement in Band 4 biosynthesis. Finally, I investigated whether siderophores could be detected in serum of patients at risk for invasive aspergillosis (IA) caused by A. fumigatus. We used UPLC-MS/MS to quantify the major A. fumigatus siderophore, N,N',N"-triacetylfusarinine C (TAFC) in serum. In >90 serum samples from at-risk patients, TAFC was diagnostic in 29 samples, and identified in an additional 28 serum samples. TAFC was not detected in healthy serum. Thus, serum siderophore detection may be a useful tool in the diagnosis of IA caused by A. fumigatus.
Download or read book Iron Transport in Bacteria written by Jorge H. Crosa and published by Amer Society for Microbiology. This book was released on 2004 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: provides an up–to–date survey of iron transport systems in bacteria; details iron transport and its regulation in E.colias a prototype for iron transport systems in gram–negative bacteria; includes chapters on the major gram–negative, gram–positive and acid–fast bacterial pathogens – their iron transport systems and the roles of these systems in virulence; presents structural studies of siderophores, heme carriers, and iron transport proteins; discusses the ecology of siderophores and potential therapeutic uses of siderophores.
Download or read book The Physiology of Fungal Nutrition written by D. H. Jennings and published by Cambridge University Press. This book was released on 1995-03-09 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of how nutrients enter a fungus and their fate once inside the cell. 2000 references.
Download or read book Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites written by Juan-Francisco Martín and published by Springer. This book was released on 2014-09-09 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.
Download or read book Fungal Respiratory Infections in Cystic Fibrosis written by Jean-Philippe Bouchara and published by Frontiers Media SA. This book was released on 2022-01-05 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Iron Siderophores and Plant Diseases written by T. R. Swinburne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of competition for iron in the interactions between saprophytic microorganisms, pathogens and plants has been recognised for almost a decade. This has been reflected i.n an upsurge of publications on the topic over the last five years. Paradoxically, the subject was only touched upon during the International Congress of Plant Pathology held in 1983. In response to this apparent omission, a few of those most closely associated with the topic met one evening during which they resolved to organise a symposium devoted solely to the various aspects of iron uptake and its relation to plant disease. It was my privilege to be asked to undertake the task of convenor. &arly correspondence brought a wealth of positive replies to the proposal, particularly from Bob Schippers in Baarn. With the increasing costs of international symposia the need for a sponsor soon became apparent and an application to NATO was favourabiy received, following helpful advice from Dr. di Lullo, Advanced Research Workshop Programme Director, to whom all the participants in this Workshop owe a debt of gratitude.
Download or read book Metal Ions in Fungi written by Gunther Winkelmann and published by CRC Press. This book was released on 2020-08-26 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the latest advances in the study of the intracellular fate and transport of metal ions in fungi, emphasizing the mechanisms that regulate cellular concentration. The book explains the expanding relationship between molecular genetics and inorganic biochemistry.
