Download or read book Fungal Immunology written by Paul L. Fidel and published by Springer Science & Business Media. This book was released on 2006-04-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunology of Fungal Infections written by Gordon D. Brown and published by Springer Science & Business Media. This book was released on 2007-05-10 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.

Download or read book Immunity to Human Fungal Pathogens Mechanisms of Host Recognition Protection Pathology and Fungal Interference written by Steven P. Templeton and published by Frontiers Media SA. This book was released on 2019-01-24 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergence of antifungal-resistant strains. It is therefore of interest to increase our understanding of host-pathogen interactions in order to facilitate the development of new therapies for individuals suffering from fungal infection and disease. These early interactions are shaped by an array of constituent and secreted factors that stimulate or inhibit host immune responses toward protective or detrimental immunity. Likewise, an array of preformed factors and tissue-resident cells provide early protection from fungal infection and provide extracellular signals that result in localized recruitment of inflammatory cells and determine the character of subsequent adaptive antifungal immunity. This Research Topic explores the host and fungal pathways that program innate and adaptive immunity and the immune cells, molecules, and regulatory pathways that comprise protective or detrimental responses to fungal exposure or infection. Over 200 authors contributed reviews, opinions, or original research focusing on antifungal immunity in humans and in experimental models. We believe that the results of these efforts provide a benchmark for further advances and improved antifungal therapies.

Download or read book Fungal Infections and Immune Responses written by Juneann W. Murphy and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years, there has been an almost explosive increase in interest and studies concerning the nature and mechanisms of the immune response to fungal infections. Many immunologists who are not well versed in mycology have begun to study the nature and mechanisms of antifungal immunity using a wide variety of newer as well as more conventional immunologic technologies, both in vivo and in vitro. Up to the 1980s, however, there was little interest among basic immunologists concerning fungal immunity. This situation has changed dramatically in the past half decade, mainly because of AIDS.

Download or read book Human Fungal Pathogen Identification written by Thomas Lion and published by Humana. This book was released on 2016-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related to pathogenicity, susceptibility, and response to treatment. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Human Fungal Pathogen Identification: Methods and Protocols serves as an ideal reference for researchers investigating the ever-growing worldwide healthcare problems involving fungal infections.

Download or read book Immunogenetics of Fungal Diseases written by Agostinho Carvalho and published by Springer. This book was released on 2017-04-03 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.

Download or read book Infection and Immunity written by D H Davies and published by CRC Press. This book was released on 2002-09-11 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise text explores the interactions between pathogens and the immune system. Taking a disease-based approach, it explains how micro-organisms adapted to growth in human hosts can evade the immune system and cause disease. The opening chapter overviews the innate and adaptive immune responses to microbes. Subsequent chapters are specific to particular pathogens, beginning with their biology and leading on to illustrate mechanisms of adaptation and ensuing consequences. Each of these chapters ends with a summary, review questions and further reading lists. Summaries, review questions and further reading make this book suitable for self-directed study. Infection and Immunity is ideal for any undergraduates taking a course that explores the interaction between pathogens and the human immune system.

Download or read book Nijkamp and Parnham s Principles of Immunopharmacology written by Michael J. Parnham and published by Springer Nature. This book was released on 2019-12-10 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Download or read book Laboratory Protocols in Fungal Biology written by Vijai Kumar Gupta and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Protocols in Fungal Biology presents the latest techniques in fungal biology. This book analyzes information derived through real experiments, and focuses on cutting edge techniques in the field. The book comprises 57 chapters contributed from internationally recognised scientists and researchers. Experts in the field have provided up-to-date protocols covering a range of frequently used methods in fungal biology. Almost all important methods available in the area of fungal biology viz. taxonomic keys in fungi; histopathological and microscopy techniques; proteomics methods; genomics methods; industrial applications and related techniques; and bioinformatics tools in fungi are covered and complied in one book. Chapters include introductions to their respective topics, list of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting. Each chapter is self-contained and written in a style that enables the reader to progress from elementary concepts to advanced research techniques. Laboratory Protocols in Fungal Biology is a valuable tool for both beginner research workers and experienced professionals. Coming Soon in the Fungal Biology series: Goyal, Manoharachary / Future Challenges in Crop Protection Against Fungal Pathogens Martín, García-Estrada, Zeilinger / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites Zeilinger, Martín, García-Estrada / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 van den Berg, Maruthachalam / Genetic Transformation Systems in Fungi Schmoll, Dattenbock / Gene Expression Systems in Fungi Dahms / Advanced Microscopy in Mycology

Download or read book Fungal Infections of the Central Nervous System written by Mehmet Turgut and published by Springer. This book was released on 2019-07-05 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.

Download or read book Damp Indoor Spaces and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-10-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.

Download or read book Oxford Textbook of Medical Mycology written by Christopher C. Kibbler and published by Oxford University Press. This book was released on 2017-12-14 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.

Download or read book Fungal Pathogenesis written by Richard Calderone and published by CRC Press. This book was released on 2001-10-12 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution outlines rapid identification of major mycoses utilizing antigen capture and molecular assays details signaling and phenotypic switching discusses the value of genomics in validation highlights state-of-the-art molecular methodologies to study disease-causing organisms describes available and potential antifungal drug targets and drug development considers predicting the consequences of drug resistance on patient management presents topical observations on strain typing and variation and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.

Download or read book Toll Like Receptors TLRs and Innate Immunity written by Stefan Bauer and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

Download or read book Fungal Extracellular Vesicles written by Marcio Rodrigues and published by Springer Nature. This book was released on 2022-01-01 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.

Download or read book Lectin in Host Defense Against Microbial Infections written by Shie-Liang Hsieh and published by Springer Nature. This book was released on 2020-03-09 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.