Download or read book Fundamentals of Preparative and Nonlinear Chromatography written by Georges Guiochon and published by Academic Press. This book was released on 2006-03-21 with total page 991 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Preparative and Nonlinear Chromatography is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.
Download or read book Fundamentals of Preparative and Nonlinear Chromatography written by Georges Guiochon and published by . This book was released on 2006 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary approach combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. The book covers recent developments in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on solid materials and packed columns process concepts. Final chapters on modeling and determination of model parameters, the design and optimization of preparative chromatographic processes and chromatographic reactors allow for the optimum selection of chromatographic systems. Essential for chemists and engineers working in the chemicals and pharmaceutical industries as well as for food technologies, due to the interdisciplinary nature of these processes.
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2020-02-12 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.
Download or read book Preparative Chromatography for Separation of Proteins written by Arne Staby and published by John Wiley & Sons. This book was released on 2017-02-02 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers
Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2020-02-27 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.
Download or read book Liquid Chromatography written by M. Kaspereit and published by Elsevier Inc. Chapters. This book was released on 2013-01-08 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter describes rivalling operating modes applied industrially in preparative chromatography. After recapitulating the basic features of the “workhorse” and reference in the field, namely, isocratic batch elution, at first, more-sophisticated concepts are presented that offer additional degrees of freedom but maintain the discontinuous character of the separation process. Subsequently, process options are described that possess the potential to perform the separations continuously. Hereby, mainly the most successful multicolumn concepts are explained, which are based on realizing highly efficient countercurrent transport processes. Finally, the important aspect is addressedL how different process alternatives can be evaluated and compared quantitatively.
Download or read book Advances in Chromatography written by Eli Grushka and published by CRC Press. This book was released on 2009-12-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than four decades, scientists and researchers have relied on the Advances in Chromatography Series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. With contributions from an array of international experts, the latest volume captures new developments in this important field th
Download or read book Drug Stereochemistry written by Krzysztof Jozwiak and published by CRC Press. This book was released on 2012-04-23 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology. Topics include:The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug disc
Download or read book Modern Supercritical Fluid Chromatography written by Larry M. Miller and published by John Wiley & Sons. This book was released on 2019-12-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.
Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-22 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making
Download or read book Handbook of HPLC written by Danilo Corradini and published by CRC Press. This book was released on 2016-04-19 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the
Download or read book Surface Functionalized Ceramics written by Laura Treccani and published by John Wiley & Sons. This book was released on 2022-12-12 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-Functionalized Ceramics Focused coverage of making and using functional ceramic materials for a wide variety of scientific and technical applications Surface-Functionalized Ceramics provides a comprehensive overview of surface functionalization approaches for ceramic materials, including alumina, zirconia, titania, and silica, and their uses as sensors, chemical, and biological probes, chromatographic supports for (bio)molecule purification and analysis, and adsorbents for toxic substances and pollutants. Overall, the text provides a broad picture of the enormous possibilities offered by surface functionalization and addresses the current challenges regarding surface analysis, characterization, and stability. As a well-rounded resource, the text points out opportunities of surface-functionalized ceramics, their issues such as achieving surface stability and complex analysis, and how to counter them. Edited by two experts in the field of advanced materials surfaces, Surface-Functionalized Ceramics covers topics such as: Processing methods for advanced ceramics, surface modification of ceramic materials, and methods for electrokinetic surface characteristics Surface imaging and chemical surface analysis using atomic force microscopy Surface chemical analysis and ceramic-enhanced analytics Biological and living matter-surface interactions including protein adsorption mechanisms as well as bacteria behavior in terms of biofilm formation and prevention for antibacterial applications Mesoporous silica and organosilica biosensors for water quality and environmental monitoring, plus ceramic-based adsorbents in bioproduct recovery and purification For professionals, researchers, and academics in the fields of materials science, biotechnology, biotechnological industry, environmental sciences, and ceramics industry, Surface-Functionalized Ceramics is a one-stop reference on the subject that provides different approaches to obtain surfaces of ceramic materials that perform desired functions.
Download or read book Separation Methods in Drug Synthesis and Purification written by Klara Valko and published by Elsevier. This book was released on 2020-06-19 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods. Features descriptions and applications of all separation methods used in the pharmaceutical industry Written by the leading scientists in their respective fields, providing solutions for a wide range of industrial separation problems encountered within the pharmaceutical industry Thoroughly updated with brand new separation science techniques and the latest developments in the established techniques of chromatography
Download or read book Mathematical Modeling and Scale Up of Liquid Chromatography written by Tingyue Gu and published by Springer. This book was released on 2015-04-06 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tingyue Gu's second edition provides a comprehensive set of nonlinear multicomponent liquid chromatography (LC) models for various forms of LC, such as adsorption, size exclusion, ion-exchange, reversed-phase, affinity, isocratic/gradient elution and axial/radial flow LC. Much has advanced since the first edition of this book and the author's software, described here, is now used for teaching and research in 32 different countries. This book comes together with a complete software package with graphical user interface for personal computers, offered free for academic applications. Additionally, this book provides detailed methods for parameter estimation of mass transfer coefficients, bed voidage, particle porosity and isotherms. The author gives examples of how to use the software for predicitons and scale-up. In contrast to the first edition, authors do not need to deal with complicated math. Instead, they focus on how to obtain a few parameters for simulation and how to compare simulation results with experimental data. After reading the detailed descriptions in the book, a reader is able to use the simulation software to investigate chromatographic behavior without doing actual experiments. This book is aimed at readers who are interested in learning about LC behaviors and at those who want to scale up LC for preparative- and large-scale applications. Both academic personnel and industrial practitioners can benefit from the use of the book. This new edition includes: - New models and software for pellicular (cored) beads in liquid chromatography - Introduction of user-friendly software (with graphical user interface) - Detailed descriptions on how to use the software - Step-by-step instructions on parameter estimation for the models - New mass-transfer correlations for parameter estimation - Experimental methods for parameter estimation - Several actual examples using the model for product development and scale-up - Updated literature review
Download or read book Principles and Practice of Modern Chromatographic Methods written by Kevin Robards and published by Academic Press. This book was released on 2021-12-03 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Modern Chromatographic Methods, Second Edition takes a comprehensive, unified approach in its presentation of chromatographic techniques. Like the first edition, the book provides a scientifically rigid, but easy-to-follow presentation of chromatography concepts that begins with the purpose and intent of chromatographic theory - the “what and why that are left out of other books attempting to cover these principles. This fully revised second edition brings the content up-to-date, covering recent developments in several new sections and an additional chapter on composite methods. New topics include sample profiling, sample preparation, sustainable green chemistry, 2D chromatography, miniaturization/nano-LC, HILIC, and more. Contains thorough chapters that begin with an updated schematic overview and a visual representation of the content Avoids the obfuscation of different terminologies and classification systems that are prevalent in the area, such as the relationship between liquid chromatography and column chromatography Provides integrated and comprehensive topic coverage based on chromatographic bibliometrics and survey reports on the relative usage of chromatographic techniques
Download or read book Advances in Chromatography Volume 51 written by Eli Grushka and published by CRC Press. This book was released on 2016-04-19 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 51, the series editors have invited established, well-known chemists from across the globe to offer cutting-edge revie
