Download or read book Functionalized Upconversion Nanoparticles for Cancer Imaging and Therapy written by and published by . This book was released on 2014 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multi functional Upconversion Nanoparticles for in Vivo Imaging in Vivo Tumor Suppression and Photodynamic Therapy written by Chi Fai Chan and published by . This book was released on 2016 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functionalized Nanomaterials for Cancer Research written by Hamed Barabadi and published by Elsevier. This book was released on 2024-03-22 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step by step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients' overall outcomes. The book discusses the functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. It is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment. - Provides comprehensive coverage on functionalized nanomaterials for cancer therapeutics and future developments - Explores current trends on functionalized nanomaterials for cancer research and commercial scale opportunities - Discusses real-world case studies on functionalized nanomaterials for cancer therapy and research
Download or read book Nanomedicine for Cancer Diagnosis and Therapy written by Arshi Malik and published by Springer Nature. This book was released on 2021-08-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.
Download or read book Functional Nanomaterials for Cancer Diagnostics and Therapy written by Wansong Chen and published by Frontiers Media SA. This book was released on 2021-05-18 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanomaterials for Cancer Detection Using Imaging Techniques and Their Clinical Applications written by Ramesh S. Chaughule and published by Springer Nature. This book was released on 2022-10-17 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents nanomaterials for cancer detection using a variety of state-of-the-art imaging techniques. Clinical applications are also highlighted. The unique size-dependent properties and convenient surfaces for molecular assembly make these nanomaterials essential for a variety of innovative imaging techniques. This book covers important imaging modalities, synthesis of nanoparticles with specific functional properties, and clinical applications including the development of anticancer drugs. The information presented here involves contributions from chemistry, materials science, materials characterization, cell engineering, and clinical testing. The book will be essential reading to experienced clinicians as well as a wide range of scholars and researchers interested in nanotechnology and imaging techniques for cancer detection.
Download or read book Bionanotechnology in Cancer written by D. Sakthi Kumar and published by CRC Press. This book was released on 2022-10-27 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.
Download or read book Multifunctional Theranostic Nanomedicines in Cancer written by Malay K. Das and published by Academic Press. This book was released on 2021-03-16 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment
Download or read book Design of Functionalized Nanoparticles as Imaging Agents for Cancer written by José Alejandro Barreto Solano and published by . This book was released on 2012 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes the synthesis and characterization of three different generations of iron oxide magnetic nanoparticles derivatized with macrocyclic ligands for application as bi-modal imaging agents in the detection of cancer tumors by Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET). The nanoparticles have been modified with polyethyleneglycol (PEG) in order to avoid uptake by the Reticuloendothelial System (RES), whilst the macrocyclic ligands have been introduced for chelation of the radionuclide 64Cu2+, which is detectable by PET. Apart from being a platform for the transport of the radionuclide complexes, the magnetic nanoparticles themselves act as MRI contrast agents and can be used for hyperthermia treatment of cancer due to their super paramagnetic nature. Synthesis of the first generation nanoparticles involved co precipitation of the core nanoparticles from a solution of iron(II) and iron(III) salts through addition of base. The macrocycles 1,4-bis(2-pyridylmethyl)-1,4,7-triazacyclononane (dmptacn), 1,4,7,10-tetraazacyclododecane (cyclen) and 1,4,8,11-tetraazacyclotetradecane (cyclam) were reacted with glycidyloxypropyltriethoxysilane (GPTES) to form the corresponding siloxane derivatives, which were then hydrolyzed over the surface of the nanoparticles to form a stable coating. Macrocycle loadings of the order of 0.2 mmol/g were achieved using this methodology, and the mean diameter of the nanoparticles was found to be ca. 7 nm, respective of the ligand used. Light scattering measurements showed that the particles form aggregates in solution, with a hydrodynamic size of 150-200 nm. The nanoparticles could be rapidly radiolabeled with 64Cu2+. Challenge experiments performed with an excess of cyclam indicated that the nanoparticles derivatized with dmptacn were the most resistant to 64Cu2+ leaching. These particles were also found to be the most stable in rat plasma. A second generation of nanoparticles was synthesized in order to diminish the aggregation of the nanoparticles. This involved synthesis of the core nanoparticles by co precipitation, followed by surface coating with oleic acid, which provided enhanced stability (reduced aggregation) in organic media. Displacement of the oleic acid chains with polyethylene glycol silane (PEG-silane) derivatives was used to produce a stable coating on the nanoparticles and to render them water soluble. Two different PEG-silane molecules, with different PEG chain lengths (Mn 250 and 600), were used to modified the nanoparticles. It was found that the nanoparticles coated with the longer PEG chains (PEG600) were less susceptible to aggregation in aqueous media. The nanoparticles were also functionalized with different macrocycles through amide coupling to the terminal carboxylic acid groups of the PEG chains. The nanoparticles were found to bind 64Cu2+both specifically (via the macrocycles) and nonspecifically, however the weakly boundions could be removed by addition of cyclam. In addition to MRI and PET, these second generation nanoparticles would be suitable for use in hyperthermia treatment as they possess a good specific absorption rate. The third generation nanoparticles consisted of iron oxide particles synthesized by thermal decomposition of iron oleate in the presence of oleic acid. Substitution of the surface oleate molecules by ligand exchange reaction with a PEG 600-silane derivative produced water dispersible nanoparticles with narrower size distribution and smaller hydrodynamic size than the first two generations of nanoparticles. The nanoparticles were found to accumulate in the liver after injection, as revealed by in vivo imaging studies performed on rats. The particles were further functionalized with the 64Cu2+ complex of a new dmptacn derivative, via the free carboxyl groups of the PEG chains, to produce an agent suitable for dual modal MRI-PET imaging.
Download or read book Structural DNA Nanotechnology written by Nadrian C. Seeman and published by Cambridge University Press. This book was released on 2015 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.
Download or read book Upconversion Nanoparticles UCNPs for Functional Applications written by Vijay Kumar and published by Springer Nature. This book was released on 2023-09-17 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores upconversion nanoparticles (UCNPs) at both, the fundamental as well as applied levels, for functional applications. It provides a broad perspective about the synthesis approaches of UCNPs with the preferred size, improved and tunable upconversion luminescence, along with the combined multifunctionality for various applications. It highlights the fundamentals and systematic developments in the tuning of UC emission and surface engineering of UCNPs that make UCNPs convenient for use in a large range of applications. Moreover, it gives an understanding of the imposed limitations and challenges associated with these methods to achieve the desired performance in targeted applications. It also includes the latest multifunctional lanthanide-based UCNPs, which efficiently convert low-energy photons into high-energy photons, and their applications in fluorescent microscopy, deep-tissue bioimaging, nanomedicine, optogenetics, solid-state lighting, solar cells, security labeling, and volumetric display.
Download or read book Design and Evaluation of Plasmonic Magnetic Au MFe2O4 M Fe Co Mn Core Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics written by Ravichandran Manisekaran and published by Springer. This book was released on 2017-10-30 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.
Download or read book Advanced Theranostic Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2015-06-30 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materialsis written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers – an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications
Download or read book Nanooncology written by Gil Gonçalves and published by Springer. This book was released on 2018-06-01 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.
Download or read book Gastric Cancer Prewarning and Early Diagnosis System written by Daxiang Cui and published by Springer. This book was released on 2017-06-21 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores recent developments in the application of nanotechnology in the early detection of gastric cancer. It discusses various aspects, such as screening for gastric cancer-associated biomarkers; establishing new ultrasensitive detection methods based on nanoparticle labeling and nanoeffects; developing a new generation of nanodevices for high-throughput examination of serum and breath biomarkers; developing multifunctional nanoprobes for targeted imaging and simultaneous therapy of gastric cancer; evaluating the biosafety of multifunctional nanoprobes; and the establishment of a pre-warning and early diagnosis system. It also presents clinical applications and prospects. The book provides a valuable reference for researchers in nanomedicine and clinicians involved in gastric cancer and radiology.
Download or read book Colloidal Upconverting Nanoparticle Systems for Integration in Targeting Therapeutics and Imaging Applications written by Rafik Naccache and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functionalized Nanoparticles for Use in Cancer Therapy written by Martin Lafleur and published by . This book was released on 2013 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
