Download or read book Functional Imaging and Classification of Retinal Ganglion Cells in the Living Primate Eye written by Tyler Christian Godat and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The primate fovea is perhaps the most important location for vision in the retina, being specialized for high resolution spatial and chromatic vision, but it has been traditionally difficult to study in ex vivo electrophysiology and especially in vivo. The crucial visual properties conferred by the fovea are mediated by neurons called retinal ganglion cells, which exist in twenty or more distinct types that all tile the retina and are present from the far periphery up to the inner edge of the foveal slope. Microelectrode recordings of foveal retinal ganglion cells have been challenging due to their reduced size and the fragility of tissue survival in excised retina. Some of these difficulties in observing individual cells have been overcome in the in vivo retina by combining high resolution fluorescence adaptive optics ophthalmoscopy with calcium imaging to optically record functional responses in the living primate eye. The work in this thesis advances knowledge of functional properties of retinal ganglion cells at the primate fovea by studying their responses to various stimuli in the living primate (macaca fascicularis) eye. This includes measurements of retinal ganglion cells' chromatic tuning and cone weightings, made possible by silent substitution style uniform chromatic flicker stimuli, and measurements of cells' spatial transfer functions, made possible by monochromatic drifting gratings of various spatial frequencies. In particular, the most common type of retinal ganglion cell, the midget, is studied extensively to generate a broader understanding of the specialization and importance of the primate fovea. This work thus provides a closer look at the in situ spatial, chromatic, and temporal properties of these retinal ganglion cells than ever before possible. A novel stimulation delivery arm as part of a dual adaptive optics ophthalmoscope is also developed as part of this work to improve the resolution and breadth of stimuli used to interrogate the functional properties of retinal ganglion cells. These imaging and stimulation techniques provide a suite of tools for assessing and characterizing the functional properties of retinal ganglion cells in vivo which will inform the next generation of vision restoration strategies such as optogenetics and retinal prostheses."--Pages xi-xii.
Download or read book Wavefront Sensing and High Resolution Adaptive Optics Imaging in the Living Rodent Eye written by Ying Geng and published by . This book was released on 2011 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The rodent has become an increasingly valuable model for human diseases and development due to its availability for genetic manipulations. Non-invasive microscopic imaging of the rodent retina would allow tracking of retinal development, disease progression, and the efficacy of therapy in single animals. Correction of the eye's aberrations using adaptive optics (AO) could improve the resolution of in vivo rodent retinal images, but previous attempts have been limited by the small size of its eye and the difficulty in measuring its aberrations due to poor Shack-Hartmann wavefront sensor (SHWS) spot quality. The work in this thesis describes methods developed to measure the rodent eye optics and to optimize its retinal image quality in vivo. Our first attempt was modifying a confocal fluorescence adaptive optics scanning laser ophthalmoscope (AOSLO) originally built for imaging the primate and human eye to accommodate the rat eye. Despite achieving in vivo resolution sufficient to resolve sub-cellular structures in fluorescent ganglion cells, problems were identified with aberration measurements and AO image quality. We then constructed a SHWS customized for the small mouse eye, and found a solution to the aberration measurement problem. The custom designed SHWS can favor light from a specific retinal layer and provide good wavefront spot quality. This wavefront sensor was incorporated into a confocal AOSLO custom designed for the mouse eye. High quality images were obtained in the mouse retina revealing multiple cell layers, including the photoreceptor mosaic, nerve fiber bundles, fine capillaries/blood flow, and ganglion cell bodies and fine processes. The in vivo resolution of the system was directly characterized to be sub-[micrometer] laterally, and ~10 [micrometers] axially. This fine resolution has allowed classification of ganglion cells in vivo. The value of the instrument was also demonstrated in two functional imaging scientific studies"--Leaves vii-viii.
Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Download or read book Glaucoma written by Franz Grehn and published by Springer Science & Business Media. This book was released on 2009-02-08 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third Glaucoma volume of the Essentials in Ophthalmology series, as in the first and the second, provides a picture of recent progress in the field of glaucoma, in both basic clinical research and applied clinical science. Its intention is not to replace textbooks on glaucoma, but to serve as a conceptual bridge between original research and textbook presentation. The editors have set out to provide the reader with diverse and interesting topics reflective of the evidence-based, modern approach to the field of glaucoma. The book’s well-structured text and new design is quick and easy to read.
Download or read book Handbook of Optics Devices measurements and properties written by Michael Bass and published by . This book was released on 1995 with total page 1574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation -- A new volume in the field's bestselling optics reference -- an entirely new opus focusing on x-ray, nonlinear, and vision optics -- Provides the same mix of tutorial writing with in-depth reference material that distinguished Volumes I & II.
Download or read book Retinal Imaging written by David Huang and published by Mosby. This book was released on 2006 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: SECTION I: IMAGING MODALITIES: BASIC PRINCIPLES & INTERPRETATION -- 1. Fluorescein angiography -- 2. Indocyanine green angiography -- 3. Optical coherence tomography (OCT) -- -- 4. Optical coherence tomographic ophthalmoscopy -- 5. Ultrasound -- 6. Scanning laser tomography -- 7. Scanning laser polarimetry -- 8. Retinal thickness analyzer -- 9. Adaptive optics ophthalmoscopy -- 10. Imaging of Ocular Blood Flow -- SECTION II: MACULAR DISEASES -- 11. Non-neovascular age-related macular degeneration -- -- 12. Neovascular Age-Related Macular Degeneration -- 13. Pathologic myopia -- 14. Central serous retinopathy -- 15. Macular holes -- 16. Epiretinal membranes -- 17. Macular dystrophies -- 18. Cystoid macular edema -- 19. Angiod streaks -- 20. Chrorioretinal folds -- SECTION III: RETINAL VASCULAR DISEASES -- 21. Diabetic Retinopathy -- 22. Arterial obstructive disease -- 23. Venous obstructive disease -- 24. Parafoveal Telangiectasis -- 25. Coats' disease -- 26. Retinopathy of prematurity -- 27. Ocular ischemic syndrome -- 28. Hypertensive retinopathy -- 29. Radiation retinopathy -- 30. Retinal artery macroanuerysm -- SECTION IV: INFLAMMATORY & INFECTIOUS DISEASES -- 31. Posterior Scleritis -- -- 32. Pars Planitis -- 33. Sarcoidosis -- 34. Uveal Effusion Syndrome -- 35. White Dot Syndromes -- -- 36. Sympathetic Ophthalmia -- 37. Vogt-Koyanagi-Harada Disease -- 38. Syphilis -- 39. Tuberculosis -- 40. Ocular Histoplasmosis -- 41. Fungal Infections -- 42. Endophthalmitis -- 43. Acute Retinal Necrosis -- 44. Toxoplasmosis -- 45. Toxocariasis -- 46. Cysticercosis -- 47. Diffuse Unilateral Subacute Neuroretinitis -- 48. Cytomegalovirus Retinitis -- SECTION V: OTHER RETINAL DISEASES -- 49. Ocular Phototoxicity -- 50. Metabolic and nutritional anomalies -- 51. Medications and Retinal Toxicity -- 52. Retinal injuries -- 53. Hereditary/congenital vitreoretinal disorders -- 54. Retinitis pigmentosa and allied disorders -- SECTION VI: TUMORS -- 55. Retinoblastoma -- 56. Choroidal malignant melanoma -- 57. Choroidal nevus -- 58. Cavernous hemangioma of the retina -- 59. Retinal capillary hemangioma -- 60. Choroidal hemangioma -- -- 61. Tuberous sclerosis complex -- 62. Tumors and related lesions of the retinal pigment epithelium -- 63. Congenital hypertrophy of the retinal pigment epithelium and other pigmented lesions -- 64. Choroidal/retinal metastasis -- 65. Osteomas -- 66. Leukemia /lymphomas -- SECTION VII: OPTIC NERVE DISORDERS -- 67. Optic pits -- 68. Optic nerve head drusen -- 69. Melanocytoma of the optic disc -- 70. Papilledema -- 71. Glaucoma -- 72. Other optic nerve malformations.
Download or read book Encyclopedia of Computational Neuroscience written by Dieter Jaeger and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Color Vision written by Jan Kremers and published by Springer. This book was released on 2016-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of human color vision has advanced tremendously in recent years, helped along by many new discoveries, ideas, and achievements. It is therefore timely that these new developments are brought together in a book, assembled specifically to include new research and insight from the leaders in the field. Although intentionally not exhaustive, many aspects of color vision are discussed in this Springer Series in Vision Research book including: the genetics of the photopigments; the anatomy and physiology of photoreceptors, retinal and cortical pathways; color perception; the effects of disorders; theories on neuronal processes and the evolution of human color vision. Several of the chapters describe new, state-of-the-art methods within genetics, morphology, imaging techniques, electrophysiology, psychophysics, and computational neuroscience. The book gives a comprehensive overview of the different disciplines in human color vision in a way that makes it accessible to specialists and non-specialist scientists alike. About the Series: The Springer Series in Vision Research is a comprehensive update and overview of cutting edge vision research, exploring, in depth, current breakthroughs at a conceptual level. It details the whole visual system, from molecular processes to anatomy, physiology and behavior and covers both invertebrate and vertebrate organisms from terrestrial and aquatic habitats. Each book in the Series is aimed at all individuals with interests in vision including advanced graduate students, post-doctoral researchers, established vision scientists and clinical investigators. The series editors are N. Justin Marshall, Queensland Brain Institute, The University of Queensland, Australia and Shaun P. Collin, Neuroecology Group within the School of Animal Biology and the Oceans Institute at the University of Western Australia.
Download or read book The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques written by Peng Xiao and published by Frontiers Media SA. This book was released on 2022-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Light Reflex on Retinal Arteries and Veins written by Olaf Brinchmann-Hansen and published by . This book was released on 1986 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Color Psychology written by Andrew J. Elliot and published by Cambridge University Press. This book was released on 2015-12-17 with total page 1737 pages. Available in PDF, EPUB and Kindle. Book excerpt: We perceive color everywhere and on everything that we encounter in daily life. Color science has progressed to the point where a great deal is known about the mechanics, evolution, and development of color vision, but less is known about the relation between color vision and psychology. However, color psychology is now a burgeoning, exciting area and this Handbook provides comprehensive coverage of emerging theory and research. Top scholars in the field provide rigorous overviews of work on color categorization, color symbolism and association, color preference, reciprocal relations between color perception and psychological functioning, and variations and deficiencies in color perception. The Handbook of Color Psychology seeks to facilitate cross-fertilization among researchers, both within and across disciplines and areas of research, and is an essential resource for anyone interested in color psychology in both theoretical and applied areas of study.
Download or read book Duplicity Theory of Vision written by Bjørn Stabell and published by Cambridge University Press. This book was released on 2009-08-13 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book chronicles the development of three classic theories within vision research, from the 17th century to today, focusing on duplicity theory.
Download or read book The Structure of the Retina written by Santiago Ramón y Cajal and published by . This book was released on 1972 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Stroke Syndromes 3ed written by Louis R. Caplan and published by Cambridge University Press. This book was released on 2012-07-12 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of dysfunction due to stroke, this revised edition remains the definitive guide to stroke patterns and syndromes.
Download or read book Imaging of Orbital and Visual Pathway Pathology written by Wibke S. Müller-Forell and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with imaging of pathology of the visual system. This book is divided into two parts, general and special. In the general part, important basics of modern imaging methods are discussed. The knowledge on the indication, technique, and results of functional MR imaging is also presented.
Download or read book The Cambridge Handbook of Animal Cognition written by Allison B. Kaufman and published by Cambridge University Press. This book was released on 2021-07-22 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook lays out the science behind how animals think, remember, create, calculate, and remember. It provides concise overviews on major areas of study such as animal communication and language, memory and recall, social cognition, social learning and teaching, numerical and quantitative abilities, as well as innovation and problem solving. The chapters also explore more nuanced topics in greater detail, showing how the research was conducted and how it can be used for further study. The authors range from academics working in renowned university departments to those from research institutions and practitioners in zoos. The volume encompasses a wide variety of species, ensuring the breadth of the field is explored.
