Download or read book The Evolution of Genome Size written by T. Cavalier-Smith and published by John Wiley & Sons. This book was released on 1985 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses both the evolutionary causes and the molecular mechanisms of changes in genome size. It emphasises the universal posistive correlation between genome size and cell volume, and discusses both natural and experimentally induced changes.

Download or read book Long Non coding RNA written by Antonin Morillon and published by Elsevier. This book was released on 2018-02-01 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dark side of the genome represents vast domains of the genome that are not encoding for proteins – the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms. - This book offers a large review about the long non-coding RNA - It presents the broad functional diversities of those molecules - It presents pioneer works from the field - Provides a comprehensive review of the field - Presents fundamental and therapeutic interests