Download or read book From Aspirin to Viagra written by Vladimir Marko and published by Springer. This book was released on 2020-08-12 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Aspirin to Viagra, insulin to penicillin, and vaccines to vitamin supplements, drugs have become part of our everyday lives. This staggering global industry wasn’t born overnight; advancements in pharmaceutical science have been happening for a long while, over the course of decades and even centuries. This book tells the history of ten prominent substances and how they came to be common household names. It shows how the creation of such influential drugs often began with the right person at the exactly right—or wrong!— time. The chapters tell the stories of geniuses and charlatans; scholars and amateurs; advances won through hard work or pure luck; and ultimately, the handful of resounding successes that revolutionized a global industry. Beyond the pioneers of the most famous drugs in our culture, the book analyzes how our perspective on medical treatment has shifted over the decades. Modern standards for testing and administering substances have created a new set of advantages, setbacks, and stigmas, all of which are discussed herein.
Download or read book From Aspirin to Viagra written by Vladimir Marko and published by Springer Nature. This book was released on 2020-07-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Aspirin to Viagra, insulin to penicillin, and vaccines to vitamin supplements, drugs have become part of our everyday lives. This staggering global industry wasn’t born overnight; advancements in pharmaceutical science have been happening for a long while, over the course of decades and even centuries. This book tells the history of ten prominent substances and how they came to be common household names. It shows how the creation of such influential drugs often began with the right person at the exactly right—or wrong!— time. The chapters tell the stories of geniuses and charlatans; scholars and amateurs; advances won through hard work or pure luck; and ultimately, the handful of resounding successes that revolutionized a global industry. Beyond the pioneers of the most famous drugs in our culture, the book analyzes how our perspective on medical treatment has shifted over the decades. Modern standards for testing and administering substances have created a new set of advantages, setbacks, and stigmas, all of which are discussed herein.
Download or read book Laughing Gas Viagra and Lipitor written by Jie Jack Li and published by Oxford University Press. This book was released on 2006-09-07 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Jie Jack Li is a medicinal chemist and is intimately involved with drug discovery. Through extensive research and interviews with the inventors of drugs, including those of Viagra and Lipitor, he has assembled an astounding number of facts and anecdotes, as well as much useful information about important drugs we know and use in our lives today. Figures, diagrams, and illustrations highlight the text throughout."--BOOK JACKET.
Download or read book The Drug Hunters written by Donald R. Kirsch and published by Simon and Schuster. This book was released on 2016-12-13 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery. The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.
Download or read book Side Effects The Hidden Agenda of the Pharmaceutical Drug Cartel written by and published by Present Time Books. This book was released on 2008 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Case Studies in Nurse Anesthesia written by Sass Elisha and published by Jones & Bartlett Publishers. This book was released on 2009-12-23 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Case Studies in Nurse Anesthesia provides succinct and relevant information that can be used by students and professionals in the operating room. Information is written in a question and answer format for easy understanding and the chapters are divided into surgical specialties, with a focus on the most frequently performed procedures. Each case describes the entire perioperative course and discusses the patient’s history and physical, anesthetic concerns, surgical concerns, anesthetic management, differential diagnosis, and potential complications.
Download or read book Those of Us on Earth written by Karin A. Fleischhaker and published by AuthorHouse. This book was released on 2011-06-22 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those of us on Earth depicts the trials and tribulations of two female alien-born friends who did not anticipate a forbidden love with their earth-alien guides. Yet through various devices, with the assistance of the mafia, the FBI and alien families who escaped to an ancient city in the mountains, they were able to save all of those on earth, seek a defense against the alien ship which threatened Las Vegas and trade advanced technologies to the U.S. Government for the return of a high ranking alien.
Download or read book Drug Induced Headache written by Hans-Christoph Diener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.
Download or read book The Drug Book written by Michael C. Gerald and published by Union Square + ORM. This book was released on 2013-09-03 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A beautiful and well-researched historical guide to significant drugs” from the author of The Complete Idiot’s Guide to Prescription Drugs (Library Journal). Throughout history, humans everywhere have searched for remedies to heal our bodies and minds. Covering everything from ancient herbs to cutting-edge chemicals, this book in the hugely popular Milestones series looks at 250 of the most important moments in the development of life-altering, life-saving, and sometimes life-endangering pharmaceuticals. Illustrated entries feature ancient drugs like alcohol, opium, and hemlock; the smallpox and the polio vaccines; homeopathic cures; and controversial medical treatments like ether, amphetamines, and Xanax—while shining a light on the scientists, doctors, and companies who brought them to us. “These true tales of discovery in The Drug Book by Michael C. Gerald might change the way you think about your medicine.” —The Healthy “An excellent starting point for student researchers and is very browsable for the general reader.” —Booklist
Download or read book Medicinal Chemistry written by Norma K Dunlap and published by Garland Science. This book was released on 2018-04-17 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry begins with the history of the field, starting from the serendipitous use of plant preparations to current practice of design- and target-based screening methods. Written from the perspective of practicing medicinal chemists, the text covers key drug discovery activities such as pharmacokinetics and patenting, as well as the classes and structures of drug targets (receptors, enzymes, nucleic acids, and protein-protein and lipid interactions) with numerous examples of drugs acting at each type. Selected therapeutic areas include drugs to treat cancer, infectious diseases, and central nervous system disorders. Throughout the book, historical and current examples illustrate the progress to market and case studies explore the applications of concepts discussed in the text. Each chapter features a Journal Club, as well as review and application questions to enhance and test comprehension. This textbook is ideal for upper-level undergraduates and graduate students taking a one-semester survey course on medicinal chemistry and/or drug discovery, as well as scientists entering the pharmaceutical industry.
Download or read book CDC Yellow Book 2018 Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Download or read book Powerful Medicines written by Jerry Avorn, M.D. and published by Vintage. This book was released on 2008-12-10 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you believe that the latest blockbuster medication is worth a premium price over your generic brand, or that doctors have access to all the information they need about a drug’s safety and effectiveness each time they write a prescription, Dr. Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced. This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans. In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls? Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science.
Download or read book The Rise of Viagra written by Meika Loe and published by NYU Press. This book was released on 2006-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on interviews with men who take the drug, their wives, doctors and pharmacists as well as scientists and researchers in the field, this fascinating account provides an intimate history of the Viagra's effect on America.
Download or read book The Body Hunters written by Sonia Shah and published by New Press, The. This book was released on 2012-03-13 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hailed by John le Carré as “an act of courage on the part of its author” and singled out for praise by the leading medical journals in the United States and the United Kingdom, The Body Hunters uncovers the real-life story behind le Carré's acclaimed novel The Constant Gardener and the feature film based on it. "A trenchant exposé . . . meticulously researched and packed with documentary evidence" (Publishers Weekly), Sonia Shah's riveting journalistic account shines a much-needed spotlight on a disturbing new global trend. Drawing on years of original research and reporting in Africa and Asia, Shah examines how the multinational pharmaceutical industry, in its quest to develop lucrative drugs, has begun exporting its clinical research trials to the developing world, where ethical oversight is minimal and desperate patients abound. As the New England Journal of Medicine notes, “it is critical that those engaged in drug development, clinical research and its oversight, research ethics, and policy know about these stories,” which tell of an impossible choice being faced by many of the world's poorest patients—be experimented upon or die for lack of medicine.
Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.
Download or read book Popular Mechanics written by and published by . This book was released on 1998-08 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular Mechanics inspires, instructs and influences readers to help them master the modern world. Whether it’s practical DIY home-improvement tips, gadgets and digital technology, information on the newest cars or the latest breakthroughs in science -- PM is the ultimate guide to our high-tech lifestyle.
Download or read book Countering the Problem of Falsified and Substandard Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adulteration and fraudulent manufacture of medicines is an old problem, vastly aggravated by modern manufacturing and trade. In the last decade, impotent antimicrobial drugs have compromised the treatment of many deadly diseases in poor countries. More recently, negligent production at a Massachusetts compounding pharmacy sickened hundreds of Americans. While the national drugs regulatory authority (hereafter, the regulatory authority) is responsible for the safety of a country's drug supply, no single country can entirely guarantee this today. The once common use of the term counterfeit to describe any drug that is not what it claims to be is at the heart of the argument. In a narrow, legal sense a counterfeit drug is one that infringes on a registered trademark. The lay meaning is much broader, including any drug made with intentional deceit. Some generic drug companies and civil society groups object to calling bad medicines counterfeit, seeing it as the deliberate conflation of public health and intellectual property concerns. Countering the Problem of Falsified and Substandard Drugs accepts the narrow meaning of counterfeit, and, because the nuances of trademark infringement must be dealt with by courts, case by case, the report does not discuss the problem of counterfeit medicines.
