Download or read book Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals written by Feroz Jameel and published by John Wiley & Sons. This book was released on 2010-07-13 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: A real-world guide to the production and manufacturing of biopharmaceuticals While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug products. This book helps fill the gap in the field, examining all areas of biopharmaceuticals manufacturing, from development and formulation to production and packaging. Written by a group of experts from industry and academia, the book focuses on real-world methods for maintaining product integrity throughout the commercialization process, clearly explaining the fundamentals and essential pathways for all development stages. Coverage includes: Research and early development phase appropriate approaches for ensuring product stability Development of commercially viable formulations for liquid and lyophilized dosage forms Optimal storage, packaging, and shipping methods Case studies relating to therapeutic monoclonal antibodies, recombinant proteins, and plasma fractions Useful analysis of successful and failed products Formulation and Process Development Strategies for Manufacturing Biopharma-ceuticals is an essential resource for scientists and engineers in the pharmaceutical and biotech industries, for government and regulatory agencies, and for anyone with an interest in the latest developments in the field.

Download or read book Handbook of Pharmaceutical Manufacturing Formulations Third Edition written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2019-11-25 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Two, Uncompressed Solid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this second volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features:  Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions  Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing  Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements  Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines

Download or read book Formulation and Fabrication of Food Bars written by Jack R. Durst and published by . This book was released on 1966 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Pharmaceutical Manufacturing Formulations written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2016-04-19 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing methodologies that can serve as a reference point for new formulations, the second volume covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution, and other similar products.Highlights from Uncompressed Solid Products, Volume Two include:the fundamental issues of good manufacturin

Download or read book Bioactive Delivery Systems for Lipophilic Nutraceuticals written by Ming Miao and published by Royal Society of Chemistry. This book was released on 2023-06-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing interest in the food, supplements, cosmetics, and pharmaceutical industries in improving the healthiness of their products by incorporating lipophilic bioactive substances like oil-soluble vitamins (A, D and E), omega-3 fatty acids, and nutraceuticals (carotenoids, curcuminoids and flavonoids). However, there are many challenges that need to be overcome due to their poor water-solubility, chemical stability, and bioavailability. For this reason, there is interest in the development of effective encapsulation technologies to increase the efficacy of lipophilic bioactives. This book reviews the encapsulation systems currently available for delivering lipophilic bioactives, including their preparation, functionality, and application range, including nanoemulsions, emulsions, Pickering emulsions, HIPEs, microgels, organogels and liposomes. Chapters 1-2 review the biological activity of delivery systems and lipophilic bioactives. Chapters 3-5 describe the materials and preparation methods used to assemble delivery systems. Chapters 6-17 focus on the formation and application of different kinds of delivery systems. Chapter 18 discusses future trends in the development of bioactive delivery systems. Edited and authored by world renowned scholars, the book provides a state-of-the-art overview of the design, fabrication, and utilization of delivery systems for bioactives that will be useful for academic, government, and industrial scientists in fields such as pharmaceuticals, cosmetics, agriculture, chemical engineering, nutrition, and foods.

Download or read book Nanoscale Fabrication Optimization Scale up and Biological Aspects of Pharmaceutical Nanotechnology written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2017-12-11 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. - Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products - Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years - Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Download or read book Non Stock Production written by Shigeo Shingo and published by CRC Press. This book was released on 2024-11-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shingo, whose work at Toyota provided the foundation for JIT, teaches how to implement non-stock production in your JIT manufacturing operations. The culmination of his extensive writings on efficient production management and continuous improvement, this book is an essential companion volume to his other landmark books on key elements of JIT, including SMED and poka-yoke. It covers-- Fundamental flaws in European and American production philosophies. Basic concepts for improving production systems. The "scientific thinking mechanism" -- a new approach to improvement. Implementing a production method in an age of authorized stock production. Development of production functions in the age of non-stock production. Significance of the different production systems. Dr. Shingo pulls together all the pieces of the production puzzle and thoroughly destroys the myth of the inevitability of waste and inventory.

Download or read book Surfactants Disinfectants Cleaners Toiletries Personal Care Products Manufacturing and Formulations Phenyl Naphthalene Ball Mosquito Coil Floor Cleaner Glass Cleaner Toilet Cleaner Utensil Cleaning Bar Liquid Detergent Detergent Powder Detergent Soap Liquid Soap Handwash Hand Sanitizer Herbal Shampoo Henna Based Hair Dye Herbal Cream Shaving Cream Air Freshener Shoe Polish Tooth Paste written by by P. K. Chattopadhyay B.Tech. (F.T.B.E.), P.G.D. (F.T.B.E.) (J.U.) Working Experience In Production Quality Control Lab., Project Work, R & D work with Nityakali Rice Mill & Solvents Extraction Plant, Bengal Distilleries Ltd., The Indian Yeast Company Ltd., Kusum Production Ltd., Asian Bio Food (P) Ltd., S.I.R.I., Parle Biscuits Ltd., Apex Silicated& Chemical Inds. (P) Ltd., Hayward Research Centre (Shaw Wallace Group), Niir Project Consultancy Services and published by NIIR PROJECT CONSULTANCY SERVICES. This book was released on 2021-01-01 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term surfactant comes from the words surface active agent. A surfactant is briefly defined as a material that can greatly reduce the surface tension of water when used in very low con-centrations. These are one of many different compounds that make up a detergent. They are added to remove dirt from skin, clothes and household articles particularly in kitchens and bathrooms. They are also used extensively in industry. A disinfectant or agent that frees from infection is ordinarily a chemical agent which kills disease germs or other harmful micro-organisms and is applied to inanimate objects. The specific way in which a disinfectant agent is used is dependent on both the desired objective and the infectious agent present. Growing emphasis on health, safety and sanitation is fuelling demand for disinfectants & surfactants across industries such as food processing, healthcare and consumer. Personal care industry in India is very huge and is one of the main key drivers for Indian surfactants market. Surfactants industry has a large market for consumer products. This handbook contains processes formulae of various pro-ducts and providing information regarding manufacturing method. It covers raw material suppliers, photographs of plant & machinery with supplier's contact details and some plant layout & process flow sheets. The major contents of the book are phenyl, floor cleaner, glass cleaner, toilet cleaner, mosquito coils, liquid detergent, detergent powder, detergent soap, naphthalene balls, air freshener, shoe polish, toothpaste, shaving cream, liquid soaps and hand-washes, herbal shampoo, heena based hair dye, herbal creams, utensil cleaning bar, hand sanitizer etc. It will be a standard reference book for professionals, entrepre-neurs, those studying and researching in this important area and others interested in the field of surfactants, disinfectants, cleaners, toiletries, personal care products manufacturing.

Download or read book Bio Based Nanoemulsions for Agri Food Applications written by Kamel A. Abd-Elsalam and published by Elsevier. This book was released on 2022-08-04 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent agricultural, food, and pharmaceutical research focuses attention on the development of delivery systems that can encapsulate, protect, and deliver natural compounds. Nanoemulsions are recognized as the best delivery systems for natural-origin nutraceuticals and phytochemicals, having many agri-food applications. Bio-based Nanoemulsions for Agri-Food Applications provides information on food-grade nanoemulsions and their application in agriculture and the food industry. This book covers concepts, techniques, current advances, and challenges in the formulation of the application of emerging food grade nanoemulsions. Particular attention is placed on food-grade nanoemulsion production methods and components used, such as plant/microbial products, biosurfactants, cosurfactants, emulsifiers, ligand targets, and bioactive/functional ingredients. This is an important reference source for materials scientists, engineers and food scientists who are looking to understand how nanoemulsions are being used in the agri-food sector. - Provides an overview of a range of bio-based nanoemulsions used in the agrifood sector - Explores how nanotechnology improves the properties of bio-based emulsions - Assesses the major challenges of manufacturing nanoemulsions at an industrial scale

Download or read book Nanoemulsions in Food Technology written by Javed Ahmad and published by CRC Press. This book was released on 2021-10-17 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: As of late, greater efforts are being made in the use of nanoemulsion techniques to encapsulate, protect, and deliver functional compounds for food applications, given their advantages over conventional emulsification techniques. In addition, delivery systems of nano-scale dimensions use low-energy emulsification methods and exclude the need of any solvent, heat, or sophisticated instruments in their production. Divided into three sections, Nanoemulsions in Food Technology: Development, Characterization, and Applications will provide in-depth information and comprehensive discussion over technologies, physical and nanostructural characterization, as well as applicability of the nanoemulsion technique in food sciences. It describes the techniques involved in nanoemulsion characterization, mainly dealing with interfacial and nanostructural characterization of nanoemulsions, different physical characterization techniques, as well as various imaging and separation techniques involved in its characterization. Key Features Provides a detailed discussion about the technology of nanoemulsion Explains how nanoemulsion technique is helpful in using essential oils of different biological sources Presents methods of preparation and recent advancements in manufacturing along with stability perspectives of this technique. Discusses recent advancements in manufacturing and reviews the stability perspectives of nanoemulsion techniques This book contains in-depth information on a technology overview, physical and nanostructural characterization, as well as applicability of the nanoemulsion technique in food sciences. It is a concise body of information that is beneficial to researchers, industries, and students alike. The contributing authors are drawn from a rich blend of experts in various areas of scientific field exploring nanoemulsion techniques for wider applications. Also available in the Food Analysis and Properties Series: Sequencing Technologies in Microbial Food Safety and Quality, edited by Devarajan Thangardurai, Leo M.L. Nollet, Saher Islam, and Jeyabalan Sangeetha (ISBN: 9780367351182) Chiral Organic Pollutants: Monitoring and Characterization in Food and the Environment, edited by Edmond Sanganyado, Basil K. Munjanja, and Leo M.L. Nollet (ISBN: 9780367429232) Analysis of Nanoplastics and Microplastics in Food, edited by Leo. M.L. Nollet and Khwaja Salahuddin Siddiqi (ISBN: 9781138600188)

Download or read book Emulsion based Encapsulation of Antioxidants written by M. Ali Aboudzadeh and published by Springer Nature. This book was released on 2021-02-22 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The limited aqueous solubility of bioactive pharmaceutical ingredients presents a tremendous challenge in the development of new drugs. In recent years, methods have been developed to protect these sensitive bioactive compounds, namely antioxidants, with the aim of increasing the public sanitation grades. Emulsion-based systems are particularly interesting as colloidal delivery encapsulation systems, because they can easily be created from food-grade ingredients using relatively simple processing protocols. It is one of the most favorable delivery systems to increase the solubility of phytochemicals, nutraceuticals and food additives. Emulsion‐based Encapsulation of Antioxidants: Design and Performance advances the field of colloid science through the investigation of the effects of formulation and process parameters that influence emulsion production. The book offers a deeper comprehension of the technological and biological aspects of the incorporation of encapsulated compounds in food matrices and explication of their activity. Chapters provide an overview of the status of emulsion-based formulations to encapsulate antioxidants, fabrication, properties, applications, and biological fate with emphasis on systems suitable for utilization within industry. Special emphasis is placed on the antioxidant activity of the carriers being the key advantage of these emulsion-based systems. The main aim of the book is to inspire and to guide fellow scientists and students in this field. Filled with illustrations, figures, case studies, practical examples, and historical perspectives, the book can also be used as a practical handbook or graduate textbook. For industry professionals, the book presents easy-to-achieve approaches to industrial pharmaceutical production.

Download or read book Manufacturing Planning and Control written by P. Higgins and published by Springer Science & Business Media. This book was released on 1996-05-31 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many companies have adopted the approach of Material Requirements Planning (MRP) and Manufacturing Resource Planning (MRP II). Despite the improvements and broadening of the MRP framework, MRP II systems still perform poorly in certain manufacturing environments. Help is at hand. This book proposes new ideas to improve the planning activities at the strategic, tactical and execution layers in manufacturing organisations. It takes into account the diverse nature of manufacturing environments. The book presents an almost unique combination of theory tested in practice, enhancing traditional manufacturing planning approaches. It is essential reading for managers and practitioners in the field, and is also suitable as an advanced text for students in industrial engineering, manufacturing and management.

Download or read book Nanofungicides written by Kamel A Abd-Elsalam and published by Elsevier. This book was released on 2023-11-21 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano- and Nanohybrid Fungicides: Novel Applications in Plant Pathology addresses nanofungicides and the opportunities that nano-agrochemicals can provide. Organized into three parts, this book addresses the synthesis and formulation of nanofungicides and nanohybrid fungicides, as well as their sensing, degradation, and commercialization. Furthermore, the book assesses the potential hazards and safety of nanofungicdes for agroecosytems, in addition to startup, patents, regulatory concerns, and prospects. Plant scientists, plant pathologist, agriculture and food scientists, and professionals and students working in related fields will all benefit from this timely resource. - Explains the synthesis or biosynthesis of nanofungicides - Determines the active ingredients of nanofungicides - Describes the applications of nanofungicides in plant disease control and crop protection - Explores the mechanisms of antifungal activity

Download or read book The FDA and Worldwide Current Good Manufacturing Practices and Quality System Requirements Guidebook for Finished Pharmaceuticals written by José Rodríguez-Pérez and published by Quality Press. This book was released on 2014-08-15 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance book is meant as a resource to manufacturers of pharmaceuticals, providing up-to-date information concerning required and recommended quality system practices. It should be used as a companion to the regulations/standards themselves and texts on the specific processes and activities contained within the QMS. This book includes chapters on US current Good Manufacturing Practice (GMP); international GMP; global GMP guides and harmonization; detailed analysis of the requirements and guidances; missing subparts; what inspectors are looking for; and the price of noncompliance. It also includes an appendix with two tabulated comparisons: the first compares US, European-PIC/S, Canadian, and WHO cGMPs, while the second compares US cGMPs with effective quality system elements. The companion CD contains cGMP regulations for sterile products produced by aseptic processing; it also includes updated data of statistical enforcement by the FDA, both domestically and abroad; a detailed glossary; and dozens of FDA guidance documents as well as international regulations (EU and Canada) and harmonization documents (WHO, PIC/S, and ICH). A very comprehensive checklist for a cGMP audit that is based on risk management criteria is also included. Finally, a comprehensive GMP exam is also included.

Download or read book Clove Syzygium aromaticum written by Mohamed Fawzy Ramadan and published by Academic Press. This book was released on 2022-07-12 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized into four sections, Clove (Syzygium aromaticum): Chemistry, Functionality, and Applications addresses the cultivation, composition, and applications of clove, along with the chemistry, functionality, and applications of clove fixed oil, clove essential oil, and clove extracts and their role in food and medicine. Beginning with the introduction of clove, this book aims to establish a multidisciplinary discussion on the development of Syzygium aromaticum phytochemistry, technology, processing, agricultural practices, functional traits, health-enhancing potential, mechanism of action, and toxicity as well as food and nonfood uses. The studies reported in this book confirm the functional applications of Syzygium aromaticum as a medicinal plant, standing out for the significance of novel applications. This book delves into the functional, nutritional, and pharmacological traits of clove. Therefore, the book will serve as a valuable reference for food scientists, technologists, chemists, nutritionists, and pharmacists developing new pharmaceutical and food products. - Explores the chemistry and functionality of clove buds, clove oils and clove extracts - Discusses clove bioactive phytochemicals and their health-promoting potential - Presents the functional applications of clove buds, clove oils and clove extracts in food - Includes applications, literature reviews, and coverage of recent developments

Download or read book Food Emulsions written by David Julian McClements and published by CRC Press. This book was released on 2015-08-21 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the mission of the first two editions, Food Emulsions: Principles, Practices, and Techniques, Third Edition covers the fundamentals of emulsion science and demonstrates how this knowledge can be applied to control the appearance, stability, and texture of emulsion-based foods. Initially developed to fill the need for a single resource co

Download or read book Nanobiotechnology Applications in Plant Protection written by Kamel A. Abd-Elsalam and published by Springer. This book was released on 2018-08-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology can target specific agricultural problems related to plant pathology and provide new techniques for crop disease control. Plant breeders and phytopathologists are needed who can apply nanogenomics and develop nanodiagnostic technologies to accurately advance the improvement process and take advantage of the potential of genomics. This book serves as a thorough guide for researchers working with nanotechnology to address plant protection problems. Novel nanobiotechnology methods describe new plant gene transfer tools that improve crop resistance against plant diseases and increase food security. Also, quantum dots (QDs) have emerged as essential tools for fast and accurate detection of particular biological markers. Biosensors, QDs, nanostructured platforms, nanoimaging, and nanopore DNA sequencing tools have the potential to raise sensitivity, specificity, and speed in pathogen detection, thereby facilitating high-throughput analysis and providing high-quality monitoring and crop protection. Also, this book deals with the application of nanotechnology for quicker, more cost-effective, and precise diagnostic procedures of plant diseases and mycotoxins. Applications of nanotechnology in plant pests and disease control, antimicrobial mechanisms, pesticides remediation and nanotoxicity on plant ecosystem and soil microbial communities are discussed in detail. Moreover, the application of specific nanomaterials including silver, copper, carbon- or polymer-based nanomaterials and nanoemulsions are also discussed. Crops treated with safe nanofertilizers and nanopesticides will gain added value because they are free of chemical residues, decay and putative pathogens for human health, sustaining the global demand for high product quality.