Download or read book Folded Selves written by Michelle Burnham and published by Dartmouth College Press. This book was released on 2014-06-14 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Folded Selves radically refigures traditional portraits of seventeenth-century New England literature and culture by situating colonial writing within the spatial, transnational, and economic contexts that characterized the early-modern "world system" theorized by Immanuel Wallerstein and others. Michelle Burnham rethinks American literary history and the politics of colonial dissent, and her book breaks new ground in making the economic relations of investment, credit, and trade central to this new framework for early American literary and cultural study. Transcontinental colonialism and mercantile capitalism underwrote not just the emerging world system but New World writing -- suggesting that early modern literary aesthetics and the early modern economy helped to sponsor each other. Burnham locates in New England's literature of dissent -- from Ma-re Mount to the Salem witchcraft trials -- a persistent use of economic language, as well as competing economies of style. The brilliance of Burnham's study is that it exposes the transoceanic material and commercial concerns of colonial America's literature and culture of dissent.
Download or read book Folding and Self assembly of Biological Macromolecules written by Eric Westhof and published by World Scientific. This book was released on 2004 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers - and audience interaction - are edited and illustrated versions of the transcribed oral presentations.
Download or read book Protein Folding and Self Avoiding Walks Polyhedral Studies and Solutions written by Agnes Dittel and published by Logos Verlag Berlin GmbH. This book was released on 2008 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The protein folding problem refers to the correlation of a protein's amino acid sequence and its native three-dimensional structure which is essential for functionality. It still constitutes one of the major challenges in computational biology. One commonly studied model for the protein folding problem is the HP lattice model in which proteins are considered in a fairly abstract representation. However, the HP model proteins exhibit significant parallels to proteins occurring in nature. The solution of the HP lattice mode as a combinatorial optimization problem has been proven to be NP-complete, and there have already been developed various different approaches for efficient algorithms. We study an integer programming formulation of the problem. Starting with an analysis of this model, where we concentrate on symmetry issues, we show how the model can be consolidated by exploiting symmetry properties of the underlying lattice. The main focus lies in the development of specific components of a branch-and-cut framework for the computation of solutions for the HP model by means of integer programming methods. In order to understand the structure of the model, we perform a series of polyhedral studies from which we derive two main classes of cutting planes. Furthermore, we exploit the knowledge of folding principles which are also valid for HP model proteins for the development of related branching strategies. For the solution of a special class of instances, we present an implementation of a genetic algorithm for the generation of primal feasible start solutions. Finally, we document the performance of the methods developed for each of the four topics (model consolidation, primal method, branching strategy and cutting planes) within the branch-and-cut procedure. We present computational results for different types of lattices, where we both consider known benchmark instances from literature and random instances.
Download or read book Folded Synthetic Peptides for Biomedical Applications written by Alessandro Contini and published by Frontiers Media SA. This book was released on 2019-09-26 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequential arrangement, induce secondary structures peptides. Such building blocks include D- and other non-proteinogenic amino acids, as well as beta- and gamma-amino acids. This Research Topic comprises a collection of papers by an international group of 77 scientists with a background in synthetic, analytical, computational and medicinal chemistry, as well as in biochemistry and pharmacology. Their research is presented here in a total of 11 papers (8 original research reports and 3 reviews), covering diverse aspects of folded synthetic peptides. These studies include the preparation and characterization of new peptide monomers with interesting folding properties, the synthesis and conformational analysis of non-natural peptides, as well as the use of folded peptidomimetics as molecular switches. Additionally, a range of biomedical applications, such as antimicrobial, anti-inflammatory, antiangiogenic and immune-stimulating activities, are also reported. We hope this eBook will be a source of inspiration and knowledge for scientist in various disciplines related to folded peptides and their many applications, as well as for those who want to learn more about this fascinating field of research.
Download or read book The Man Who Folded Himself written by David Gerrold and published by ReadHowYouWant.com. This book was released on 2011-02-02 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic work of science fiction is widely considered to be the ultimate time-travel novel. When Daniel Eakins inherits a time machine, he soon realizes that he has enormous power to shape the course of history. He can foil terrorists, prevent assassinations, or just make some fast money at the racetrack. And if he doesn't like the results of the change, he can simply go back in time and talk himself out of making it! But Dan soon finds that there are limits to his powers and forces beyond his control.
Download or read book The Folded Clock written by Heidi Julavits and published by Anchor. This book was released on 2016-03-08 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable Book Rereading her childhood diaries, Heidi Julavits hoped to find incontrovertible proof that she was always destined to be a writer. Instead, they “revealed me to possess the mind of a phobic tax auditor.” Thus was born a desire to try again, to chronicle her daily life—now as a forty-something woman, wife, mother, and writer. A meditation on time and self, youth and aging, friendship and romance, faith and fate, and art and ambition, in The Folded Clock one of the most gifted prose stylists in American letters explodes the typically confessional diary form with her trademark humor, honesty, and searing intelligence.
Download or read book On Folding written by Michael Friedman and published by transcript Verlag. This book was released on 2016-05-31 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only recently, with the increasing interest in origami and folding in natural sciences and the humanities, that the fold as a new conception in a whole range of disciplines has begun to be conceived in a broader way. Folding as a material and structural process offers a new methodology to think about the close relationship of matter, form and code. It henceforth crosses out old dichotomies, such as the organic and the inorganic or nature and technology, and blurs the boundaries between experimental, conceptual and historical approaches. This anthology aims to unfold this new interdisciplinary field and its disciplinary impact, ranging from materials science, biology, architecture, and mathematics to literature and philosophy.
Download or read book Molecular Biology of Protein Folding Part B written by P. Michael Conn and published by Academic Press. This book was released on 2009-01-09 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. Follow the new editor-in-chief, P. Michael Conn, as he introduces this second thematic volume in the series – an in-depth aid to researchers who are looking for the best techniques and tools for understanding the complexities of protein folding Understand the advantages of protein folding over other therapeutic approaches and see how protein folding plays a critical role in the development of diseases such as Alzheimer’s and diabetes Decipher the rules of protein folding through compelling and timely reviews combined with chapters written by international authors in engineering, biochemistry, physics and computer science
Download or read book The College of Life Or Practical Self written by Henry Davenport Northrop and published by . This book was released on 1896 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Self Culture written by and published by . This book was released on 1897 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Official Gazette of the United States Patent Office written by USA Patent Office and published by . This book was released on 1914 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Canadian Patent Office Record and Register of Copyrights and Trade Marks written by and published by . This book was released on 1908 with total page 1670 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Universal Graphic Dictionary of the English Language Self pronouncing written by William Joseph Pelo and published by . This book was released on 1925 with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Universal Graphic Dictionary of the English Language Self pronouncing written by and published by . This book was released on 1922 with total page 1140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Paradise of Childhood written by Edward Wiebé and published by . This book was released on 1869 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Your Spacious Self written by Stephanie Bennett Vogt and published by Red Wheel/Weiser. This book was released on 2023-09-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revised and expanded edition of Your Spacious Self. Author and space-clearing expert Stephanie Bennett Vogt invites readers to clear their homes and restore their spirits by releasing the clutter that prevents them from experiencing who they really are. It's a jungle...in here! Behind our stress, clutter, and confusion is an infinitely spacious place one might call stillness or joy. This is our natural state of being, but we usually don't experience it, because we are caught in a web of material possessions, desires, and fears. Our clutter, writes Vogt, a longtime space clearing expert, "becomes like another member of the family that we feed, house, and lug around." She shows us that it's not our stuff, but the holding on to it that creates a force field of "stuck-ness" that clouds our perceptions and paralyzes our lives. Clutter is not just the junk spilling out of the closet. It is any thing or thought that prevents us from experiencing who we truly are. Clearing is not a tedious exercise of throwing away, but a gentle journey of letting go - one small step, drawer, or moment at a time. With all-new nourishing lessons in slowing down, simplifying, and self-care, Your Spacious Self shows you how to clear your home, quiet the mind, and restore your spirit, in ways that feel good and last a lifetime. Included are daily tips and meditations, a weekly worksheet, and guidelines for starting and maintaining a clearing support group--perfect for book groups and support groups. This updated and 10th anniversary edition replaces the previously published edition (9780981877181).
Download or read book Pictures from Italy Sketches by Boz and American Notes written by Charles Dickens and published by . This book was released on 1877 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
