Download or read book Fluoride And Fluorosis Interaction Symptoms Prevalence And Mitigation written by Arjun L Khandare and published by . This book was released on 2021-05-15 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since the pioneering research in fluorosis has been undertaken at ICMR-National Institute of Nutrition, Hyderabad in the year 1937, the first case of fluorosis was identified in cattle in Kanagiri, Prakasam district, Andhra Pradesh. Since then, the fluoride and fluorosis research is being continued at ICMR-National Institute of Nutrition. Fluorosis is a disease that is caused due to excess fluoride in drinking and cooking water which can be easily prevented by safe drinking water. The non-availability of a book in layman's language consisting of various research papers/articles on fluorosis and related areas inspired the author to compile his 25 years of research findings in a simple language that can easily be understood by the common people. The book has covered 20 chapters in various thematic areas like epidemiological studies, basic research (animals), applied research in humans, mechanistic studies, fluorosis mitigation, education and training, and dissemination of knowledge. The epidemiological studies, studies were conducted in 5 districts of Tamil Nadu, Nellore and Prakasam district of Andhra Pradesh, Nalgonda district of Telangana, Doda district of Jammu, and Kashmir, Nawada district of Bihar, and KarbiAnglong of Assam. These studies were conducted to understand the prevalence and severity of disease, its etiology, and various dietary factors including environmental factors which enhance or reduce the burden of fluoride toxicity in the study areas. The basic studies have been conducted in animal models/species (dog, guinea pig, rabbit, and rat) to understand organ toxicity, various biomarkers, and toxicokinetics of fluoride toxicity and its mitigation by tamarind. The efficacy of mitigation of fluoride toxicity by tamarind pulp was evaluated in humans in the field set up. Whereas, the mechanistic studies related to the enhanced excretion of fluoride through urine and reduced deposition in bone by tamarind intervention were assessed in laboratory conditions in rats, which has been also supported by the insilico studies. As of now, no medicine is available to treat fluorosis; hence, the dietary intervention to mitigate fluorosis has been a challenging area to study. Our basic and translational studies using tamarind to mitigate fluorosis were the aim of the author's research. The research conducted by the author has great potential for further dissemination of knowledge in the area of fluorosis and fluoride research. The knowledge was disseminated in the form of training programs to the health functionaries of the affected districts of the country under the National Programme for Prevention and Control of Fluorosis, Ministry of Health and Family Welfare, Government of India. In the capacity of the President for the International Society for Fluoride Research, the author had successfully conducted XXXIII Conference of the International Society for Fluoride Research through which the importance of fluoride research was disseminated globally.
Download or read book Fluoride in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2007-01-22 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.
Download or read book Fluoride in Drinking Water written by A.K. Gupta and published by CRC Press. This book was released on 2016-04-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the Health Effects of Fluoride PollutionFluoride in Drinking Water: Status, Issues, and Solutions establishes the negative impacts of naturally occurring fluoride on human health and considers the depth and scope of fluoride pollution on an international scale. The book discusses current global water quality and fluoride-related issues and
Download or read book Dietary Reference Intakes for Calcium Phosphorus Magnesium Vitamin D and Fluoride written by Institute of Medicine and published by National Academies Press. This book was released on 1999-10-17 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1941, Recommended Dietary Allowances (RDAs) has been recognized as the most authoritative source of information on nutrient levels for healthy people. Since publication of the 10th edition in 1989, there has been rising awareness of the impact of nutrition on chronic disease. In light of new research findings and a growing public focus on nutrition and health, the expert panel responsible for formulation RDAs reviewed and expanded its approachâ€"the result: Dietary Reference Intakes. This new series of references greatly extends the scope and application of previous nutrient guidelines. For each nutrient the book presents what is known about how the nutrient functions in the human body, what the best method is to determine its requirements, which factors (caffeine or exercise, for example) may affect how it works, and how the nutrient may be related to chronic disease. The first volume of Dietary Reference Intakes includes calcium, phosphorus, magnesium, vitamin D, and fluoride. The second book in the series presents information about thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Based on analysis of nutrient metabolism in humans and data on intakes in the U.S. population, the committee recommends intakes for each age groupâ€"from the first days of life through childhood, sexual maturity, midlife, and the later years. Recommendations for pregnancy and lactation also are made, and the book identifies when intake of a nutrient may be too much. Representing a new paradigm for the nutrition community, Dietary Reference Intakes encompasses: Estimated Average Requirements (EARs). These are used to set Recommended Dietary Allowances. Recommended Dietary Allowances (RDAs). Intakes that meet the RDA are likely to meet the nutrient requirement of nearly all individuals in a life-stage and gender group. Adequate Intakes (AIs). These are used instead of RDAs when an EAR cannot be calculated. Both the RDA and the AI may be used as goals for individual intake. Tolerable Upper Intake Levels (ULs). Intakes below the UL are unlikely to pose risks of adverse health effects in healthy people. This new framework encompasses both essential nutrients and other food components thought to pay a role in health, such as dietary fiber. It incorporates functional endpoints and examines the relationship between dose and response in determining adequacy and the hazards of excess intake for each nutrient.
Download or read book Fluoride in Drinking water written by John Kirtley Fawell and published by World Health Organization. This book was released on 2006 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluoride is known to occur at elevated concentration in a number of parts of the world, where it can be a significant cause of disease. The primary focus of this book is the prevention of adverse health effects from excessive levels of fluoride in drinking water. The book fills the urgent need, identified for updating the WHO Guidelines for Drinking-water Quality, for information on the occurrence of fluoride, its health effects, ways of reducing excess levels, and methods for analysis of fluoride in water. The draft document, produced by a working group of experts convened to consider protection from fluoride and its control, was issued for extensive review and consultation. The resultant book, which incorporates the comments received, was further peer reviewed by experts in developed and developing countries. It is aimed at a wide range of individuals, including health workers and sanitary engineers who may require a broad introduction to the subject with more detailed guidance in some specific areas. Fluoride in Drinking-waterwill be an invaluable reference source for all those concerned with the management of drinking water containing fluoride and the health effects arising from its consumption, including water sector managers and practitioners, as well as health sector staff at policy and implementation levels. It will also be of interest to researchers, students, development workers, and consultants.
Download or read book Fluorine and Health written by Alain Tressaud and published by Elsevier. This book was released on 2008-06-06 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics
Download or read book Prevalence and Severity of Dental Fluorosis in the United States 1999 2004 written by Eugenio D. Beltrán-Aguilar and published by . This book was released on 2010 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Dental fluorosis refers to changes in the appearance of tooth enamel that are caused by long-term ingestion of fluoride during the time teeth are forming. Studies conducted in the 1930s showed that the severity of tooth decay was lower and dental fluorosis was higher in areas with more fluoride in the drinking water. In response to these findings, community water fluoridation programs were developed to add fluoride to drinking water to reach an optimal level for preventing tooth decay, while limiting the chance of developing dental fluorosis. By the 1980s, studies in selected U.S. communities reported an increase in dental fluorosis, paralleling the expansion of water fluoridation and the increased availability of other sources of ingested fluoride, such as fluoride toothpaste (if swallowed) and fluoride supplements. This report describes the prevalence of dental fluorosis in the United States and changes in the prevalence and severity of dental fluorosis among adolescents between 1986-1987 and 1999-2004. Data from the National Health and Nutrition Examination Survey, 1999-2004 and the 1986-1987 National Survey of Oral Health in U.S. School Children." - p. 1.
Download or read book Fluorides in Caries Prevention written by John J. Murray and published by Butterworth-Heinemann. This book was released on 1991 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Download or read book Coal burning Type of Endemic Fluorosis written by Zhi-Zhong Guan and published by Springer Nature. This book was released on 2021-11-18 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endemic fluorosis is caused by excessive intake of fluorine in drinking water, air, food, tea and other media in a specific natural environment for a long time, which involves at least 25 countries, such as China, India, Vietnam, Iran, Egypt, Mexico, Argentina and influences more than 200 million of population. China and India are the countries with the most extensive endemic fluorosis and the most serious damages. There are three main intake sources of endemic fluorosis, e.g., drinking water, coal-burning pollution and drinking tea. Coal-burning type of endemic fluorosis was established in Guizhou Province of China in 1970’s. The residents in the areas used indoor stoves with no flue to burn coals with high content of fluoride to bake grains in the autumn and heat in the winter. This results in excessive intake of fluorine and then leads chronic poisoning. It has been confirmed that 13 provinces of China with 34.3 million of population are influenced by this type of fluorosis with severe injuries to most organs of human body. The content of this book covers the epidemiology, pathological changes, molecular pathogenesis and clinical treatments of the disease. This book is a suitable reference for the researchers and graduate students in this field, which is helpful to improve the understanding of this disease and to take preventive measures.
Download or read book The Case Against Fluoride written by Paul H. Connett and published by Chelsea Green Publishing. This book was released on 2010 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the case of water fluoridation, the chemicals used to fluoridate the water that more than 180 million people drink each day are not pharmaceutical grade, but rather hazardous waste products of the phosphate fertilizer industry; it is illegal to dump them into rivers and lakes or release them into the atmosphere. And water fluoridation is a prime example of one of the worst medical practices possible-forced medication with no control over the dose or who gets it. Perhaps most shocking of all, it is not subject to any federal regulation. At once painstakingly-documented and also highly-readable, The Case Against Fluoride brings new research to light, including links between fluoride and harm to the brain, bones, and kidneys, and argues that while there is possible value in topical applications like brushing your teeth with fluoride toothpaste, the evidence that swallowing fluoride reduces tooth decay is surprisingly weak.
Download or read book Systematic Reviews in Health Care written by Matthias Egger and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
Download or read book Toxicological Profile for Fluorides Hydrogen Fluoride and Fluorine written by and published by . This book was released on 1993 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reviews of Environmental Contamination and Toxicology Volume 211 written by David M. Whitacre and published by Springer Science & Business Media. This book was released on 2011-02-03 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Download or read book Scientific Knowledge in Controversy written by Brian Martin and published by SUNY Press. This book was released on 1991-01-01 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Knowledge in Controversy: The Social Dynamics of the Fluoridation Debate is a study of today's most heated and long-lived health controversy as well as a study of the role of power in science. It uses the tools of sociology of knowledge and political economy to analyze battles over scientific evidence and the struggle for scientific credibility, the exercise of professional power to suppress opponents, and the role of corporate interests in the debate. The evidence from a variety of countries offers a new perspective on the fluoridation issue and also shows how to link the analysis of rhetoric in scientific disputes with the wider analysis of power in society.
Download or read book Planning and Care for Children and Adolescents with Dental Enamel Defects written by Bernadette K. Drummond and published by Springer. This book was released on 2014-11-24 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defective development of tooth enamel or dentin is a significant dental problem for children and adolescents in various respects, and dentists and other oral health workers find managing these problems challenging and stressful. While a considerable amount of relevant research is currently being undertaken, much further investigation is needed. This book discusses the known causes of defective dental enamel and explains why it is so difficult to restore. Most importantly, it presents the signs and symptoms that allow accurate diagnosis and documents the best contemporary management. The full range of enamel defects is considered, including defects in primary teeth and permanent teeth, associated syndromes, molar incisor hypomineralization, and genetic defects. The clinical chapters are well illustrated, providing clear guidelines for each procedure. In addition, avenues for future research are identified, with explanation of their rationale.
Download or read book Advancing Oral Health in America written by Institute of Medicine and published by National Academies Press. This book was released on 2012-01-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though it is highly preventable, tooth decay is a common chronic disease both in the United States and worldwide. Evidence shows that decay and other oral diseases may be associated with adverse pregnancy outcomes, respiratory disease, cardiovascular disease, and diabetes. However, individuals and many health care professionals remain unaware of the risk factors and preventive approaches for many oral diseases. They do not fully appreciate how oral health affects overall health and well-being. In Advancing Oral Health in America, the Institute of Medicine (IOM) highlights the vital role that the Department of Health and Human Services (HHS) can play in improving oral health and oral health care in the United States. The IOM recommends that HHS design an oral health initiative which has clearly articulated goals, is coordinated effectively, adequately funded and has high-level accountability. In addition, the IOM stresses three key areas needed for successfully maintaining oral health as a priority issue: strong leadership, sustained interest, and the involvement of multiple stakeholders from both the public and private sectors. Advancing Oral Health in America provides practical recommendations that the Department of Health and Human Services can use to improve oral health care in America. The report will serve as a vital resource for federal health agencies, health care professionals, policy makers, researchers, and public and private health organizations.
