Download or read book Fluka written by Alfredo Ferrari and published by . This book was released on 2005 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Biology written by Julio E. Celis and published by Elsevier. This book was released on 2006 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems. This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies. Topics covered include: Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocytochemistry (Volume 1) Organelle and Cellular Structures, Assays (Volume 2) Imaging Techniques, Electron Microscopy, Scanning Probe and Scanning Electron Microscopy, Microdissection, Tissue Arrays, Cytogenetics and In Situ Hybridization, Genomics and Transgenic Knockouts and Knock-down Methods (Volume 3) Transfer of Macromolecules, Expression Systems, Gene Expression Profiling (Volume 4) Indispensable bench companion for every life science laboratory Provides the latest information on the plethora of technologies needed to tackle complex biological problems Includes numerous illustrations, some in full color, supporting steps and results
Download or read book Proteins Peptides and Amino Acids SourceBook written by John Stephen White and published by Springer Science & Business Media. This book was released on 2002-04-15 with total page 1071 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins, Pep tides and Amino Acids SourceBook is the second in a series of reference books conceived to cover the explosive growth in commercially available biological reagents. The success of our first reference work, Source Book of Enzymes published in 1997, encouraged us to continue this series. Choosing proteins, peptides, and amino acids as the subject matter for the second volume was simple, given their preeminence in regulating biochemical processes and their importance to modern molecular biology. The SourceBook series was inspired by our difficulty in locating a suitable replacement for a depleted reagent in the midst of an urgent research project. To our dismay, we found the reagent supplier out of business and the product line no longer available. Other reagent catalogs on our library bookshelf offered a narrow selection and incom plete functional information. We were ultimately able to locate a satisfactory alternative only by making countless inquiries and paging through innumerable product catalogs and technical data sheets. We needed-but could not find-a single resource that cataloged available compounds, organized them in a logical and accessible format, provided critical technical information to distinguish one from another, and told us where we could buy them.
Download or read book Advanced Asymmetric Synthesis written by G.R. Stephenson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric synthesis is one of the most critical strategic subjects in organic chemistry, and this book describes advanced techniques and their applications to the industrial and laboratory synthesis of important chiral molecules. The international team of highly respected authors provide rigorous and concise reviews of their areas of expertise.
Download or read book Advanced Monte Carlo for Radiation Physics Particle Transport Simulation and Applications written by Andreas Kling and published by Springer Science & Business Media. This book was released on 2014-02-22 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the state of the art of Monte Carlo methods in radiation physics and particle transport simulation and applications. Special attention is paid to algorithm development for modeling, and the analysis of experiments and measurements in a variety of fields.
Download or read book Synthesis and Analytics of Rigidified Peptide Architectures Neuropeptide Y Dipeptide Scan Ring Chain Equilibria of Iminopeptides Thiazole Amino Acids for Thiopeptide Antibiotics written by Sebastian Enck and published by Logos Verlag Berlin GmbH. This book was released on 2010 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The architectures (three-dimensional shapes) of peptides determine their respective biological functions. Therefore, the correct alignment of functionalities in a structure by constraining the flexibility is a key process in evolution as well as in medicinal chemistry in order to increase binding affinity and selectivity. The rigidification of a peptide chain can have local effects (incorporation of the amino acid proline) or it can globally restrain flexibility (macrocyclization). Furthermore, the combination of both strategies has given rise to complex antibiotics with highly optimized modes of action. This work approaches these principles in three topics and for different purposes. The first chapter presents a novel scanning strategy which utilizes synthetic local rigidifications for the evaluation of Neuropeptide Y structure and receptor binding patterns. The fundamental process of macrocyclization is topic of the second chapter. For iminopeptides, ring-chain equilibria can be established and controlled, thereby allowing for the thermodynamic analysis of the ring closure. This leads to the identification of structural determinants that influence the inclination of a peptide chain to close the ring. In the third chapter, a sugarbased synthetic pathway leading to highly functionalized thiazole dipeptides is described. This strategy led to the synthesis of core motivs of complex thiopeptide antibiotics, as well as to diastereomers and homologs thereof.
Download or read book Predicting the T2K Neutrino Flux and Measuring Oscillation Parameters written by Tomislav Vladisavljevic and published by Springer Nature. This book was released on 2020-09-14 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports the calculation of neutrino production for the T2K experiment; the most precise a priori estimate of neutrino production that has been achieved for any accelerator-based neutrino oscillation experiment to date. The production of intense neutrino beams at accelerator facilities requires exceptional understanding of chains of particle interactions initiated within extended targets. In this thesis, the calculation of neutrino production for T2K has been improved by using measurements of particle production from a T2K replica target, taken by the NA61/SHINE experiment. This enabled the reduction of the neutrino production uncertainty to the level of 5%, which will have a significant impact on neutrino oscillation and interaction measurements by T2K in the coming years. In addition to presenting the revised flux calculation methodology in an accessible format, this thesis also reports a joint T2K measurement of muon neutrino and antineutrino disappearance, and the accompanying electron neutrino and antineutrino appearance, with the updated beam constraint.
Download or read book Handbook of X ray Imaging written by Paolo Russo and published by CRC Press. This book was released on 2017-12-14 with total page 2606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing chapter contributions from over 130 experts, this unique publication is the first handbook dedicated to the physics and technology of X-ray imaging, offering extensive coverage of the field. This highly comprehensive work is edited by one of the world’s leading experts in X-ray imaging physics and technology and has been created with guidance from a Scientific Board containing respected and renowned scientists from around the world. The book's scope includes 2D and 3D X-ray imaging techniques from soft-X-ray to megavoltage energies, including computed tomography, fluoroscopy, dental imaging and small animal imaging, with several chapters dedicated to breast imaging techniques. 2D and 3D industrial imaging is incorporated, including imaging of artworks. Specific attention is dedicated to techniques of phase contrast X-ray imaging. The approach undertaken is one that illustrates the theory as well as the techniques and the devices routinely used in the various fields. Computational aspects are fully covered, including 3D reconstruction algorithms, hard/software phantoms, and computer-aided diagnosis. Theories of image quality are fully illustrated. Historical, radioprotection, radiation dosimetry, quality assurance and educational aspects are also covered. This handbook will be suitable for a very broad audience, including graduate students in medical physics and biomedical engineering; medical physics residents; radiographers; physicists and engineers in the field of imaging and non-destructive industrial testing using X-rays; and scientists interested in understanding and using X-ray imaging techniques. The handbook's editor, Dr. Paolo Russo, has over 30 years’ experience in the academic teaching of medical physics and X-ray imaging research. He has authored several book chapters in the field of X-ray imaging, is Editor-in-Chief of an international scientific journal in medical physics, and has responsibilities in the publication committees of international scientific organizations in medical physics. Features: Comprehensive coverage of the use of X-rays both in medical radiology and industrial testing The first handbook published to be dedicated to the physics and technology of X-rays Handbook edited by world authority, with contributions from experts in each field
Download or read book Ion Selective Electrode Reviews written by J. D. R. Thomas and published by Elsevier. This book was released on 2013-10-22 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion-Selective Electrode Reviews, Volume 5 is a collection of articles that covers ion-speciation. The book aims to present the advancements of the range and capabilities of selective ion-sensors. The topics covered in the selection are neutral carrier based ion-selective electrodes; reference electrodes and liquid junction effects in ion-selective electrode potentiometry; ion transfer across water/organic phase boundaries and analytical; and carbon substrate ion-selective electrodes. The text will be of great use to chemists and chemical engineers.
Download or read book Blood cells in nuclear medicine part II written by Gerhard F. Fueger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: G. F. FUEGER Among the many processes in Physiology few appear mo~e inviting to be studied by tracers and external imaging than the variety of the routes of migratory (blood) cells in health and disease. Much emphasis has been placed lately on the methods of labelling of the white blood cells. It is obviously quite important and necessary to refine the methods of leucocytic labelling, particularly to search for ways to label selectively a specific group of white blood cells, but there is also the need to review and keep abreast with the developing knowledge of the white blood cells themselves, especially their behaviour under pathological conditions, as seen by histology and scintigraphy, their biological properties, their immunological characteristics and the mechanisms of the control of leucocytic functions. Similarly, it appears desirable to analyze animal models of inflammation as well as to review the dosimetry and the biodistribution of labelled white blood cells in humans. This book is the result of a cooperative effort to review certain highlights of the physiology of leucocytes, labelled and unlabelled, as a corollary to the effort concerning the labelling of white blood cells. In preparing this book we aim for a better understanding and definition of the goals to be achieved by the successful labelling of the migratory cells of the body. XI CONTRIBUTORS Becker, H. Medizinische Universitaetsklinik der Uni versitaet Graz, Graz, Landeskrankenhaus, haus, Austria Bjurman, B. Department of Radiation Physics, General Hospital, Malmoe, Sweden Chiles, C.
Download or read book Charged Particles in Oncology written by Marco Durante and published by Frontiers Media SA. This book was released on 2018-01-31 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
Download or read book Molecular Morphology in Human Tissues written by Gerhard W. Hacker and published by CRC Press. This book was released on 2004-12-29 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Morphology in Human Tissues: Techniques and Applications presents the most advanced molecular morphological techniques to date. This integrated approach to molecular morphology provides powerful analytical and diagnostic tools at the genome level, making the diagnosis and management of cancer, viral infections, and other diseases more pre
Download or read book Ion Selective Microelectrodes written by Daniel Ammann and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microelectrode technique is today the most widely used method in electrophy siology. Microelectrodes offer a unique approach to measurements of electrical pa rameters and ion activities of single cells. Several important breakthroughs in trans port physiology have arisen from microelectrode studies. Undoubtedly, there is a progressively wide-spread use of conventional and ion-selective microelectrodes. Due to their particular dimension and properties micro electrodes are exclusive ly applied to measurements on living matter. This must have many consequences to my thoughts on experiments with microelectrodes. In this book, my concern is fo cussing on the description of an intracellular method that should lead to reliable in formation on cellular parameters. The methodical basis for any meaningful applica tion is treated extensively. However, technical perfection and accurate results are not the only concern when working on animals and human beings. Rather, my thoughts are governed by the intellectual and moral mastery of the experimental ap proach on living subjects. A measurement with microelectrodes usually necessitates the sacrifice of an ani mal. This is an immense fact, and means that the knowledge gained by the experi ment must justify the death of a living subject.
Download or read book Calculating X ray Tube Spectra written by Gavin Poludniowski and published by CRC Press. This book was released on 2022-05-09 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calculating x-ray tube spectra provides a comprehensive review of the modelling of x-ray tube emissions, with a focus on medical imaging and radiotherapy applications. It begins by covering the relevant background, before discussing modelling approaches, including both analytical formulations and Monte Carlo simulation. Historical context is provided, based on the past century of literature, as well as a summary of recent developments and insights. The book finishes with example applications for spectrum models, including beam quality prediction and the calculation of dosimetric and image-quality metrics. This book will be a valuable resource for postgraduate and advanced undergraduate students studying medical radiation physics, in addition to those in teaching, research, industry and healthcare settings whose work involves x-ray tubes. Key Features: Covers simple modelling approaches as well as full Monte Carlo simulation of x-ray tubes Bremsstrahlung and characteristic contributions to the spectrum are discussed in detail Learning is supported by free open-source software and an online repository of code.
Download or read book Calorimetry In Particle Physics Proceedings Of The Tenth International Conference Calor02 written by Ren-yuan Zhu and published by World Scientific. This book was released on 2003-01-16 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Conference on Calorimetry in Particle Physics is the major forum for the state-of-the-art developments of calorimetry technologies. The Tenth Conference was attended by more than 150 physicists from 16 countries and covered all aspects of calorimetric particle detection and measurements, with emphasis on high energy physics and astrophysics experiments.The proceedings contain three parts: introductory papers, contributed papers and perspective papers. The introduction starts with a historical review of calorimetry developments, and continues with overviews of the current status of calorimetry in high energy physics and astrophysics, which are followed by discussions on calorimetry in future accelerator facilities, such as linear colliders and the Super B factories. A “hot” technology regarding the “energy flow concept” is also discussed. The contributed papers are organized in 11 sessions. The perspective papers summarize the physics and limitation of calorimeter applications in high energy physics, astrophysics and medical industries.
Download or read book Radiation in Medicine and Biology written by Pandit B. Vidyasagar and published by CRC Press. This book was released on 2017-05-08 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the conventional and emerging applications of radiations, which include radio waves and ultraviolet and gamma radiations. It discusses new techniques in radiation therapy and the effects of ionizing radiations on biological systems. The applications of radiations in the synthesis and use of nanoparticles along with the effects of hypergravity indicate a new trend. The book offers a concise account of the latest studies carried out so far and shows the new initiatives to be undertaken in the field of medicine and biology. It covers the medical use of radiations, such as ferrous sulfate–benzoic acid–xylenol orange dosimetry, Co-60 tomotherapy, radio-electro-chemotherapy, and fractional radiotherapy, and radiobiological effects, such as the effects of cell phone radiations on human health parameters and the combined effects of radiations and hypergravity on plants.
Download or read book Porins of Lyme Disease and Relapsing Fever Spirochetes written by Marcus Thein and published by BoD – Books on Demand. This book was released on 2012 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
