Download or read book Flexible Fabrication of Three dimensional Multi layered Microstructures Using a Scanning Laser System written by Hui Yu and published by . This book was released on 2006 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: With the rapid development of microfluidic systems, there is high demand for fabrication methods for the micro-components that can be used to realize complex three-dimensional (3D) geometrics and high integration levels. In this research, we developed a scanning laser system, which allows rapid processing of freeform multi-layered microstructures. More importantly it enables rapid prototyping of three-dimensional microdevices at low cost. The capabilities of three-dimensional manufacturing, inclined patterning, and multi-layered manufacturing have been demonstrated. Specifically, both in-plane and out-of-plane processing is feasible using spot-by-spot controllable laser pulsing. The laser processing perpendicular to the specimen surface is realized by fine-tuning the sample focal level and laser intensity. A variety of 3D microstructures have been created which including: oblique micropillar arrays, micro T-plugs, embedded microchannels, and freestanding microcantilevers with controllable beam thickness. Micro-optical components such as concave and convex microlenses have been manufactured and characterized. Many microfluidic microstructures/microdevices, for example microvalve, electrostatic regulator and microparticle capture chip, have been developed by utilizing the three-dimensional and multi-layered manufacturing capabilities of our direct UV laser writing. Furthermore, we have successfully applied our technology for biomedical instrumentation. For example, the manufacture of hollow metallic microneedle array has been demonstrated and its ability of penetrating into skin has been studied. Our system has also been adapted for scanning measuring the dynamics of single cells. The primary material we used for initial process validation is SU-8. However, the manufacture of a board range of materials such as metals and semiconductors by using the ultrafast scanning laser has also been demonstrated. ompared to the existing manufacturing techniques, our method greatly simplifies fabrication processes, potentially reducing the design-to-fabrication time to a few hours. Furthermore, the process can be set up in a conventional manufacturing environment without the need for clean room facilities. The rapid and low-cost characteristics allow our method to be extremely beneficial during the product development stages. The results presented in this research serve as the first crucial step towards the rapid manufacturing of microdevices with mechanical, optical, and/or biological functionalities.

Download or read book Microfluidics and Nanofluidics Handbook written by Sushanta K. Mitra and published by CRC Press. This book was released on 2016-04-19 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive handbook presents fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications of microfluidics and nanofluidics. The second volume focuses on topics related to experimental and numerical methods. It also covers fabrication and applications in a variety of areas, from aerospace to biological systems. Reflecting the inherent nature of microfluidics and nanofluidics, the book includes as much interdisciplinary knowledge as possible. It provides the fundamental science background for newcomers and advanced techniques and concepts for experienced researchers and professionals.

Download or read book Microfluidics and Nanofluidics Handbook 2 Volume Set written by Sushanta K. Mitra and published by CRC Press. This book was released on 2011-09-20 with total page 1767 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, two-volume handbook on Microfluidics and Nanofluidics, this text covers fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications with special emphasis on the energy sector. Each chapter begins with introductory coverage to a subject and then narrows in on advanced techniques and concepts, thus making it valuable to students and practitioners. The author pays special attention to applications of microfluidics in the energy sector and provides insight into the world of opportunities nanotechnology has to offer. Figures, tables, and equations to illustrate concepts.

Download or read book Fabrication of Three Dimensional Microstructures by UV Laser induced Polymerization written by Xinming Huang and published by . This book was released on 1996 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Femtosecond Laser Micromachining written by Roberto Osellame and published by Springer Science & Business Media. This book was released on 2012-03-05 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Femtosecond laser micromachining of transparent material is a powerful and versatile technology. In fact, it can be applied to several materials. It is a maskless technology that allows rapid device prototyping, has intrinsic three-dimensional capabilities and can produce both photonic and microfluidic devices. For these reasons it is ideally suited for the fabrication of complex microsystems with unprecedented functionalities. The book is mainly focused on micromachining of transparent materials which, due to the nonlinear absorption mechanism of ultrashort pulses, allows unique three-dimensional capabilities and can be exploited for the fabrication of complex microsystems with unprecedented functionalities.This book presents an overview of the state of the art of this rapidly emerging topic with contributions from leading experts in the field, ranging from principles of nonlinear material modification to fabrication techniques and applications to photonics and optofluidics.

Download or read book 3D Laser Microfabrication written by Hiroaki Misawa and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough introduction to 3D laser microfabrication technology, leading readers from the fundamentals and theory to its various potent applications, such as the generation of tiny objects or three-dimensional structures within the bulk of transparent materials. The book also presents new theoretical material on dielectric breakdown, allowing a better understanding of the differences between optical damage on surfaces and inside the bulk, as well as a look into the future. Chemists, physicists, materials scientists and engineers will find this a valuable source of interdisciplinary knowledge in the field of laser optics and nanotechnology.

Download or read book 3D Printing of Pharmaceuticals written by Abdul W. Basit and published by Springer. This book was released on 2018-08-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.

Download or read book Laser Micro Nano Manufacturing and 3D Microprinting written by Anming Hu and published by Springer Nature. This book was released on 2020-11-28 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the latest advances in laser techniques for micro-nano-manufacturing and an in-depth analysis of applications, such as 3D printing and nanojoining. Lasers have gained increasing significance as a precise tool for advanced manufacturing. Written by world leading scientists, the first part of the book presents the fundamentals of laser interaction with materials at the micro- and nanoscale, including multiphoton excitation and nonthermal melting, and allows readers to better understand advanced processing. In the second part, the authors focus on various advanced fabrications, such as laser peening, surface nanoengineering, and plasmonic heating. Finally, case studies are devoted to special applications, such as 3D printing, microfluidics devices, energy devices, and plasmonic and photonic waveguides. This book integrates both theoretical and experimental analysis. The combination of tutorial chapters and concentrated case studies will be critically attractive to undergraduate and graduate students, researchers, and engineers in the relevant fields. Readers will grasp the full picture of the application of laser for micro-nanomanufacturing and 3D printing.

Download or read book A Focus on SLM and SLS Methods in 3D Printing written by Emerald Group Publishing Limited and published by Emerald Group Publishing. This book was released on 2015-10-29 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Focus on SLM and SLS Methods in 3D Printing is an indispensable collection of articles for anyone involved in additive manufacturing - from academics and researchers through to engineers and managers within the manufacturing industry.

Download or read book Soft lithographical Fabrication of Three dimensional Photonic Crystals in the Optical Regime written by Jae-Hwang Lee and published by . This book was released on 2006 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes several projects to realize low-cost and high-quality three-dimensional (3D) microfabrication using non-photolithographic techniques for layer-by-layer photonic crystals. Low-cost, efficient 3D microfabrication is a demanding technique not only for 3D photonic crystals but also for all other scientific areas, since it may create new functionalities beyond the limit of planar structures. We have developed an advanced microtransfer molding technique, called two-polymer microtransfer molding (2P-[mu]TM) that shows an extremely high yield in layer-by-layer microfabrication sufficient to produce highly layered microstructures. The use of two different photo-curable prepolymers, a filler and an adhesive, allows for fabrication of layered microstructures without thin films between layers. Second, we also had to develop an alignment technique. We studied the 1st-order diffracted moiré fringes of transparent multilayered structures comprised of irregularly deformed periodic patterns. We demonstrate the alignment method for the case of layer-by-layer microstructures using soft lithography. The alignment method yields high contrast of fringes even when the materials being aligned have very weak contrasts. The imaging method of diffracted moiré fringes is a versatile visual tool for the microfabrication of transparent deformable microstructures in layer-by-layer fashion. Third, we developed several methods to convert a polymer template to dielectric or metallic structures, for instance, metallic infiltration using electrodeposition, metallic coating using sputter deposition, dielectric infiltration using titania nano-slurry, and dielectric coating using atomic layer deposition of Titania. By several different developed techniques, high quality photonic crystals have been successfully fabricated; however, I will focus on a line of techniques to reach metallic photonic crystals in this dissertation since they are completely characterized at this moment. In addition to the attempts for photonic crystal fabrication, our non-photolithographic technique is applied for other photonic applications such as small optical waveguides whose diameter is comparable to the wavelength of guided light. By 2P-[mu]TM, we achieve low cost, high yield, high fidelity, and tailorable fabrication of small waveguides. Embedded semiconductor quantum-dots and grating couplers are used for efficient internal and external light source, respectively.

Download or read book Micro Total Analysis Systems 2004 written by Thomas Laurell and published by Royal Society of Chemistry. This book was released on 2004 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Laser Assisted Fabrication of Materials written by Jyotsna Dutta Majumdar and published by Springer Science & Business Media. This book was released on 2012-11-03 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laser assisted fabrication involves shaping of materials using laser as a source of heat. It can be achieved by removal of materials (laser assisted cutting, drilling, etc.), deformation (bending, extrusion), joining (welding, soldering) and addition of materials (surface cladding or direct laser cladding). This book on ́Laser assisted Fabrication’ is aimed at developing in-depth engineering concepts on various laser assisted macro and micro-fabrication techniques with the focus on application and a review of the engineering background of different micro/macro-fabrication techniques, thermal history of the treated zone and microstructural development and evolution of properties of the treated zone.

Download or read book Microelectromechanical Systems written by and published by . This book was released on 2004 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Microtas 2004 written by Thomas Laurell and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Eighth International Conference on Miniaturized Systems in Chemistry and Life Science - MicroTas 2004 - is an annual meeting focusing on the research, development and application of miniaturized technologies and methodologies in chemistry and life science. The conference is celebrating its tenth anniversary after the first workshop at the University of Twente, The Netherlands in 1994. This research field is rapidly developing and changing towards a domain where core competence areas such as microfluidics, micro- and nanotechnology, materials science, chemistry, biology, and medicine are melting together to a truly interdisciplinary meeting place. This volume is the second in a two volume set, a valuable reference collection to all working in this field.

Download or read book Soft Lithographical Fabrication of Three dimensional Photonic Crystals in the Optical Regime written by and published by . This book was released on 2006 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes several projects to realize low-cost and high-quality three-dimensional (3D) microfabrication using non-photolithographic techniques for layer-by-layer photonic crystals. Low-cost, efficient 3D microfabrication is a demanding technique not only for 3D photonic crystals but also for all other scientific areas, since it may create new functionalities beyond the limit of planar structures. However, a novel 3D microfabrication technique for photonic crystals implies the development of a complete set of sub-techniques for basic layer-by-layer stacking, inter-layer alignment, and material conversion. One of the conventional soft lithographic techniques, called microtransfer molding (?TM), was developed by the Whitesides group in 1996. Although ?TM technique potentially has a number of advantages to overcome the limit of conventional photolithographic techniques in building up 3D microstructures, it has not been studied intensively after its demonstration. This is mainly because of technical challenges in the nature of layer-by-layer fabrication, such as the demand of very high yield in fabrication. After two years of study on conventional ?TM, We have developed an advanced microtransfer molding technique, called two-polymer microtransfer molding (2P-?TM) that shows an extremely high yield in layer-by-layer microfabrication sufficient to produce highly layered microstructures. The use of two different photo-curable prepolymers, a filler and an adhesive, allows for fabrication of layered microstructures without thin films between layers. The capabilities of 2P-?TM are demonstrated by the fabrication of a wide-area 12-layer microstructure with high structural fidelity. Second, we also had to develop an alignment technique. We studied the 1st-order diffracted moire fringes of transparent multilayered structures comprised of irregularly deformed periodic patterns. By a comparison study of the diffracted moire fringe pattern and detailed microscopy of the structure, we show that the diffracted moire fringe can be used as a nondestructive tool to analyze the alignment of multilayered structures. We demonstrate the alignment method for the case of layer-by-layer microstructures using soft lithography. The alignment method yields high contrast of fringes even when the materials being aligned have very weak contrasts. The imaging method of diffracted moire fringes is a versatile visual tool for the microfabrication of transparent deformable microstructures in layer-by-layer fashion. Third, we developed several methods to convert a polymer template to dielectric or metallic structures, for instance, metallic infiltration using electrodeposition, metallic coating using sputter deposition, dielectric infiltration using titania nano-slurry, and dielectric coating using atomic layer deposition of Titania. By several different developed techniques, high quality photonic crystals have been successfully fabricated; however, I will focus on a line of techniques to reach metallic photonic crystals in this dissertation since they are completely characterized at this moment. In addition to the attempts for photonic crystal fabrication, our non-photolithographic technique is applied for other photonic applications such as small optical waveguides whose diameter is comparable to the wavelength of guided light. Although, as guiding medium, polymers have tremendous potential because of their enormous variation in optical, chemical and mechanical properties, their application for optical waveguides is limited in conventional photolithography. By 2P-?TM, we achieve low cost, high yield, high fidelity, and tailorable fabrication of small waveguides. Embedded semiconductor quantum-dots and grating couplers are used for efficient internal and external light source, respectively.

Download or read book Micro and Nanosystems written by David A. LaVan and published by . This book was released on 2004 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, a continuation of the MEMS, NEMS, and molecular machines symposium of the 2002 MRS Fall Meeting, is devoted to the investigation of materials and device behavior at the micro-, nano-, and molecular scale as well as interdisciplinary work futhering the design and development of micro-, nano-, and molecular devices. New materials and fabrication techniques are introduced, and ongoing issues such as reliability, surface effects, processing and packaging, biocompatibility, and stability are discussed. Projects coupling micro-and nanoscale approaches to solve ongoing issues in the development of small-scale systems are featured. Topics include: nanotechnology; alternative fabrication techniques; micro- and nanofluidics; applied micro- and nanotechnology; mechanical properties; biotechnology and nanotechnology; alternative materials and metrology; and surface engineering and tribology.

Download or read book Femtosecond Laser 3D Micromachining for Microfluidic and Optofluidic Applications written by Koji Sugioka and published by Springer Science & Business Media. This book was released on 2013-09-24 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Femtosecond lasers opened up new avenue in materials processing due to its unique features of ultrashort pulse width and extremely high peak intensity. One of the most important features of femtosecond laser processing is that strong absorption can be induced even by materials which are transparent to the femtosecond laser beam due to nonlinear multiphoton absorption. The multiphoton absorption allows us to perform not only surface but also three-dimensionally internal microfabrication of transparent materials such as glass. This capability makes it possible to directly fabricate three-dimensional microfluidics, micromechanics, microelectronics and microoptics embedded in the glass. Further, these microcomponents can be easily integrated in a single glass microchip by the simple procedure using the femtosecond laser. Thus, the femtosecond laser processing provides some advantages over conventional methods such as traditional semiconductor processing or soft lithography for fabrication of microfluidic, optofludic and lab-on-a-chip devices and thereby many researches on this topic are currently being carried out. This book presents a comprehensive review on the state of the art and future prospects of femtosecond laser processing for fabrication of microfluidics and optofludics including principle of femtosecond laser processing, detailed fabrication procedures of each microcomponent and practical applications to biochemical analysis.