Download or read book Fifty years of progress in structural chemistry and molecular biology written by Linus Pauling and published by . This book was released on 1970 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A History of Molecular Biology written by Michel Morange and published by Harvard University Press. This book was released on 2000 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Download or read book The Molecular Vision of Life written by Lily E. Kay and published by Oxford University Press, USA. This book was released on 1993 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fascinating study examines the rise of American molecular biology to disciplinary dominance, focusing on the period between 1930 and the elucidation of DNA structure in the mid 1950s. Research undertaken during this period, with its focus on genetic structure and function, endowed scientists with then unprecedented power over life. By viewing the new biology as both a scientific and cultural enterprise, Lily E. Kay shows that the growth of molecular biology was a result of systematic efforts by key scientists and their sponsors to direct the development of biological research toward a shared vision of science and society. She analyzes the motivations and mechanisms empowering this vision by focusing on two key institutions: Caltech and its sponsor, the Rockefeller Foundation. Her study explores a number of vital, sometimes controversial topics, among them the role of private power centers in shaping scientific agenda, and the political dimensions of "pure" research. It also advances a sobering argument: the cognitive and social groundwork for genetic engineering and human genome projects was laid by the American architects of molecular biology during these early decades of the project. This book will be of interest to molecular biologists, historians, sociologists, and the general reader alike.
Download or read book The Engines of Hippocrates written by Barry Robson and published by John Wiley & Sons. This book was released on 2009-05-27 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique, integrative look at information-based medicine The convergence of medical science, biology, pharmacology, biomedical engineering, healthcare, and information technology is revolutionizing medical and scientific practice, and has broader social implications still being understood. The Engines of Hippocrates provides a unique, integrative, and holistic look at the new paradigm of information-based medicine, covering a broad range of topics for a wide readership. The authors take a comprehensive approach, examining the prehistory, history, and future of medicine and medical technology and its relation to information; how history led to such present-day discoveries as the structure of DNA, the human genome, and the discipline of bioinformatics; and what the future results of these discoveries may hold. Their far-ranging views are their own and not necessarily those of the IBM Corporation or other employers. The Engines of Hippocrates helps readers understand: Forces shaping the pharmaceutical and biomedical industries today, including personalized medicine, genomics, data mining, and bionanotechnology The relationship between pharmaceutical science today and other disciplines such as philosophy of health, history, economics, mathematics, and computer science The integrated role alternative and non-Western medicines could play in a new, information-based medicine Practical, ethical, organizational, technological, and social problems of information-based medicine, along with a novel data-centric computing model and a self-adaptive software engineering model, and corresponding information technology architectures, including perspectives on sharing remote data efficiently and securely for the common good An unmatched, cross-disciplinary perspective on the big picture of today and tomorrow's medicine, The Engines of Hippocrates provides a reference to interested readers both inside and outside the pharmaceutical and medical communities, as well as a peerless classroom supplement to students in a wide variety of disciplines.
Download or read book The 20th Century O Z written by Frank N. Magill and published by Routledge. This book was released on 2013-05-13 with total page 1418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume of the Dictionary of World Biography contains 250 entries on the lives of the individuals who shaped their times and left their mark on world history. This is not a who's who. Instead, each entry provides an in-depth essay on the life and career of the individual concerned. Essays commence with a quick reference section that provides basic facts on the individual's life and achievements. The extended biography places the life and works of the individual within an historical context, and the summary at the end of each essay provides a synopsis of the individual's place in history. All entries conclude with a fully annotated bibliography.
Download or read book The Black Box of Biology written by Michel Morange and published by Harvard University Press. This book was released on 2020-06-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Download or read book Partners in Science written by Robert E. Kohler and published by University of Chicago Press. This book was released on 1991 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Kohler shows exactly how entrepreneurial academic scientists became intimate "partners in science" with the officers of the large foundations created by John D. Rockefeller and Andrew Carnegie, and in so doing tells a fascinating story of how the modern system of grant-getting and grant-giving evolved, and how this funding process has changed the way laboratory scientists make their careers and do their work. "This book is a rich historical tapestry of people, institutions and scientific ideas. It will stand for a long time as a source of precise and detailed information about an important aspect of the scientific enterprise. . .It also contains many valuable lessons for the coming years."—John Ziman, Times Higher Education Supplement
Download or read book The Path to the Double Helix written by Robert Olby and published by Courier Corporation. This book was released on 2013-05-13 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a noted historian of science, this in-depth account traces how Watson and Crick achieved one of science's most dramatic feats: their 1953 discovery of the molecular structure of DNA.
Download or read book Molecularizing Biology and Medicine written by Soraya de Chadarevian and published by Taylor & Francis. This book was released on 2003-09-02 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.
Download or read book Linus Pauling written by Linus Pauling and published by World Scientific. This book was released on 2001 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pt. III. Biological macromolecules. ch. 11. Hemoglobin: Oxygen bonding and magnetic properties papers SP 82 to SP -- ch. 12. Antibodies: Structure and function papers SP 88 to SP 94 -- ch. 13. The alpha helix and the structure of proteins papers SP 95 to SP 111 -- ch. 14. Molecular biology: The role of large molecules in life and evolution papers SP 112 to SP 121 -- pt. IV. Health and medicine. ch. 15. Molecular disease papers SP 122 to SP 126 -- ch. 16. Physiological chemistry, effects of radiation, and health hazards papers SP 127 to SP 133 -- ch. 17. Orthomolecular medicine papers SP 134 to SP 144 -- pt. V. Summary of Linus Pauling's life and scientific work. ch. 18. Biographical memoir, by Prof. Jack D. Dunitz
Download or read book Linus Pauling Selected Scientific Papers In 2 Volumes Volume 2 written by Barclay Kamb and published by World Scientific. This book was released on 2001-11-02 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Linus Pauling wrote a stellar series of over 800 scientific papers spanning an amazing range of fields, some of which he himself initiated. This book is a selection of the most important of his writings in the fields of quantum mechanics, chemical bonding (covalent, ionic, metallic, and hydrogen bonding), molecular rotation and entropy, protein structure, hemoglobin, molecular disease, molecular evolution, the antibody mechanism, the molecular basis of anesthesia, orthomolecular medicine, radiation chemistry/biology, and nuclear structure. Through these papers the reader gets a fresh, unfiltered view of the genius of Pauling's many contributions to chemistry, chemical physics, molecular biology, and molecular medicine.
Download or read book The Enculturated Gene written by Duana Fullwiley and published by Princeton University Press. This book was released on 2011-11-27 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 1980s, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. After casual observations of how patients managed this painful blood disorder, the researchers in question postulated that the Senegalese type was less severe. The Enculturated Gene traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell "mild" in a social setting where public health priorities and economic austerity programs have forced people to improvise informal strategies of care. Duana Fullwiley shows how geneticists, who were fixated on population differences, never investigated the various modalities of self-care that people developed in this context of biomedical scarcity, and how local doctors, confronted with dire cuts in Senegal's health sector, wittingly accepted the genetic prognosis of better-than-expected health outcomes. Unlike most genetic determinisms that highlight the absoluteness of disease, DNA haplotypes for sickle cell in Senegal did the opposite. As Fullwiley demonstrates, they allowed the condition to remain officially invisible, never to materialize as a health priority. At the same time, scientists' attribution of a less severe form of Senegalese sickle cell to isolated DNA sequences closed off other explanations of this population's measured biological success. The Enculturated Gene reveals how the notion of an advantageous form of sickle cell in this part of West Africa has defined--and obscured--the nature of this illness in Senegal today.
Download or read book Legends in Their Own Time written by Anthony Serafini and published by Springer. This book was released on 2013-10-07 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: America's scientific giants of the 20th century have transformed the world in terms of scientific understanding, military preparedness, and the quality and comfort of our daily lives. In this exquisitely written book, Anthony Serafini - a respected historian and philosopher of science - regales the reader with vivid descriptions of the lives and contributions of the men and women who explored the depth of molecular structure, relativity, astronomy, quantum mechanics, nuclear research, and much, much more. These evocative and stunning portrayals of some of the greatest scientists who ever lived delve into the personalities and opinions of these pioneers. Furthermore, Serafini makes their significant discoveries accessible and meaningful to everyone. You will meet the indefatigable Lee De Forest, whose passion for wireless telegraphy resulted in the Audion Radio Tube, which broadcasted radio to thousands of America's living rooms. The roster of distinguished scientists continues with Ernest Lawrence, who began his academic career with the hope of becoming a physician. He later succumbed to the enticement of physics, becoming the first to discover how to unleash the unimaginable power within the nucleus. This discovery ultimately led to the creation of the atomic bomb. In addition, Robert Millikan astounded the scientific community by measuring the charge of an electron and convincing even the most hardened skeptics of the validity of the atomic theory of matter. Legends in Their Own Time recounts the most exciting events that took place during the Manhattan Project. It also explores the ongoing search for a Unified Field Theory of the cosmos - a goal that eluded even Albert Einstein. Serafini traces the evolution of scientists in America from a group of lackluster journeymen to world-renowned professionals, rivaling the scientific titans of Europe. This perceptive author portrays how the combination of politics and war has ironically contributed to the advancement of science. Through the author's insight and skill, this remarkable book recounts the fascinating history of the scientific geniuses who have built the foundations of modern science and technology.
Download or read book A Skeptical Biochemist written by Joseph Stewart Fruton and published by Harvard University Press. This book was released on 1992 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: An eminent pioneer of modern protein chemistry, Fruton (biochemistry emeritus, Yale U.) looks back on six decades in biochemical research and education to advance stimulating thoughts about science--how it is practical, how it is explained, and how its history is written. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book The Scientific 100 written by John Simmons and published by Kensington Publishing Corp.. This book was released on 2000-09-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Who are the great scientists throughout the ages, and what exactly did they do to earn their importance? From Archimedes to Newton to Einstein to Hawking, The Scientific 100 provides the fascinating answers. Vivid biographical sketches chronicle the lives and accomplishments of the world's preeminent scientists. And in the tradition of the Citadel Press 100 Series, they are ranked provocatively in order of influence--an inspiration for lively discussion. This unique volume is a browser's treasure trove and a handy reference for the general reader. John Simmons has been associated with Current Biography for more than fifteen years. He has written frequently about Nobel laureates in science. A member of the New York Academy of Sciences, he divides his time between New York City and Paris.
Download or read book The Structural Chemistry of Linus Pauling written by Robert John Paradowski and published by . This book was released on 1972 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bibliography of the History of Medicine written by and published by . This book was released on with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:
