Download or read book Current Advances in Drug Delivery Through Fast Dissolving Disintegrating Dosage Forms written by Vikas Anand Saharan and published by Bentham Science Publishers. This book was released on 2017-05-11 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability. This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.
Download or read book Fast dissolving tablets written by Dr.G.SANDHYARANI Guggilla and published by Lulu.com. This book was released on with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fast Dissolving Tablets written by Richa Maithani and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fast Dissolving Tablets written by Anas Rasheed and published by Createspace Independent Publishing Platform. This book was released on 2015-11-11 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The performance of fast dissolving tablets depends on the technology used in their manufacture. The orally disintegrating property of the tablet is attributable to a quick ingress of water into the tablet matrix, which creates porous structure and results in rapid disintegration. Hence, the basic approaches to develop fast dissolving tablets include maximizing the porous structure of the tablet matrix, incorporating the appropriate disintegrating agent and using highly water-soluble excipients in the formulation.
Download or read book Fast Dissolving Tablets of written by Manoj M. Nitalikar and published by LAP Lambert Academic Publishing. This book was released on 2012 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most commonly employed oral dosage forms are tablets and capsules. Compressed tablets are the most widely used dosage form for a number of reasons like they are convenient, easy to use, less expensive, tamper-proof, easy to pack and ship and more stable than other oral dosage form. Also tablets lend themselves to certain special release profile products such as enteric or delayed release products. products such as enteric or delayed release products.1 Solid dosage forms like tablet and capsule are most popular and preferred drug delivery system because they have high patient compliance, relatively easy to produce, easy to market, accurate dosing, and good physical and chemical stability.Oral drug delivery has been known for decades as the most widely utilized route of administration among all the routes that have been explored for the systemic delivery of drugs via various pharmaceutical products of different dosage forms. The reason that the oral route achieved such popularity may because of its ease of administration as well as the traditional belief that by oral administration the drug is well absorbed as the food stuffs that are ingested daily.
Download or read book Development of Fast Dissolving Tablets written by Basavaraj Nanjwade and published by LAP Lambert Academic Publishing. This book was released on 2011-12 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral drug delivery has been known for decades the most widely utilized route for administration among all the route that have been explored for systemic delivery of drugs via various pharmaceutical products of different dosage forms. The reasons that the oral route has achieved such popularity may be in part attributed to its ease of administration as well as the traditional belief that by oral administration the drug is well absorbed as the food stuffs that are ingested daily. In fact, the development of a pharmaceutical product for oral delivery, irrespective of its physical form involves varying extents of optimization of dosage form characteristics within the inherent constraints of GI physiology. Therefore, a fundamental understanding of various disciplines, including GI physiology, pharmacokinetics, pharmacodynamics and formulation design are essential to achieve a systemic approach to successful development of an oral pharmaceutical dosage form. The more sophisticated a delivery system, the greater is the complexity of these various disciplines involved in the design and optimization of the system. In any case, the scientific framework required for the successful development.
Download or read book Design Development of Fast Dissolving Tablets Using Novel Techniques written by Upendra Kulkarni and published by . This book was released on 2019-08-28 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fast Dissolving Tablets Of Chlorpromazine And Promethazine written by Gudas Ganesh Kumar and published by LAP Lambert Academic Publishing. This book was released on 2012 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chlorpromazine HCl and Promethazine HCl are potent anti-emetic. The central antimuscarinic actions of antihistamines are probably responsible for their anti-emetic effects. Fast dissolving tablets of Chlorpromazine HCl and Promethazine HCl were prepared using five superdisintegrants viz; sodium starch glycolate, crospovidone, croscarmellose, L-HPC and pregelatinised starch. The tablets were evaluated for weight variation, hardness, friability, disintegration time (1 min), dissolution rate, content uniformity, and were found to be within standard limit. It was concluded that the fast dissolving tablets with proper hardness, rapidly disintegrating with enhanced dissolution can be made using selected superdisintegrants. Among the different formulations of Chlorpromazine HCl and Promethazine HCl was prepared and studied and the formulation F2 and S2 containing crospovidone, mannitol and microcrystalline cellulose combination was found to be the fast dissolving formulation. In the present study an attempt has been made to prepare fast dissolving tablets of Chlorpromazine HCl and Promethazine HCl, by using different superdisintegrants with enhanced disintegration and dissolution rate
Download or read book Fast Dissolving Tablet Of An Anti inflammatory Drug written by Kalpen Patel and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Formulation And Evaluation Of Nebivolol Hcl Fast Dissolving Tablets written by Vanitha Kondi and published by LAP Lambert Academic Publishing. This book was released on 2015-06-16 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of the present study was the formulation and evaluation of Nebivolol Hcl fast dissolving tablet by solid dispersions. Fast dissolving tablets are novel types of tablets that dissolve / disintegrate / disperse in saliva within few seconds without water.The major category of Nebivolol Hcl is in the treatment of hypertension, adrenergic beta-antagonist and vasodilator. It is a poorly soluble and require enhancement of solubility and dissolution rate in its formulation development.
Download or read book Design of Tramadol HCl Fast Dissolving Tablets Using DBP written by Ravi Varma and published by LAP Lambert Academic Publishing. This book was released on 2014-07-14 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the present work is to design and evaluate fast dissolving tablets of Tramadol Hydrochloride using dehydrated banana powder a natural excipient as binder, diluent and disintegrant.( a patient friendly dosage form) 1)To prepare a stable and robust formulation of fast dissolving tablets of Tramadol Hydrochloride 2)To carryout dissolution studies of various products prepared. The DBP is "cost effective" than the other commonly used excipients to achieve the said versatile property. Moreover, banana powder is a "Natural excipient" with nutritional supplement which normally do not have any toxic to the consumers that to in less quantity (less than100mg/Tablet). Thus, DBP could alone be used as a natural binder, diluent and disintegrant in the formulation and development of Patient friendly and fast dissolving dosage forms.
Download or read book Formulation Evaluation of Fast Dissolving Tablets to Treat Migraine written by Piyush Agarwal and published by . This book was released on 2015-05-09 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride written by Nikunj Chapla and published by LAP Lambert Academic Publishing. This book was released on 2013 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is fast dissolving tablets (FDT) of Phenylephrine Hydrochloride, a selective 1 adrenergic receptor antagonist, used for nasal decongestant and producing mydriasis effect. In present work an attempt has been made by formulating fast dissolving tablets of Phenylephrine Hydrochloride by superdisintegrants addition method using croscarmellose sodium, crospovidone and sodium starch glycolate. A total of 10 batches were prepared by using various combination and concentration of superdisintegrants and evaluated for general appearance and physical parameters, drug content, in vitro disintegration, in vitro dispersion, in vitro drug release studies, kinetic studies and stability studies. Amongst all the formulations F2 and F9 were found to be better formulations which include single superdisintegrants and combination of superdisintegrants. Finally it was concluded that FDT of Phenylephrine Hydrochloride will be used as a novel drug dosage form for pediatrics and geriatrics.
Download or read book Drug Delivery to the Oral Cavity written by Tapash K. Ghosh and published by CRC Press. This book was released on 2005-02-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.
Download or read book Formulation and Evaluation of Fast Dissolving Tablet of Thiabendazole written by Pareek Ashish Kumar and published by LAP Lambert Academic Publishing. This book was released on 2015-11-30 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast Dissolving Tablets of Thiabendazole is designed for Providing the better and effective treatment against Helminthiasis. Fast Dissolving Tablet of Thiabendazole is designed with the aim to enhance the bioavailability of the dosage form. Helminthiasis infection is very common in urban areas and particularly in the childrens that are playing in soil so the Fast dissolving tablet of Thiabendazole provide cidal action by inhibiting the enzyme fumarate reductase so it provide a safest action and effective treatment.
Download or read book Pharmaceutical Dosage Forms written by Larry L. Augsburger and published by CRC Press. This book was released on 1990-03-30 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutraceutical Fast Dissolving Tablet For Management Of Type 2 Diabetes written by Manju Pandey and published by . This book was released on 2016-07-02 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
