Download or read book Far Ultraviolet Resonance Raman Studies of Protein Components written by Leland Carter Mayne and published by . This book was released on 1988 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultraviolet Resonance Raman Spectroscopy of Proteins and Protein Components written by Robert Allen Copeland and published by . This book was released on 1986 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultraviolet Resonance Raman Spectroscopy of Proteinsandprotein Components written by Robert Allen Copeland and published by . This book was released on 1986 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Spectroscopic Methods for Determining Protein Structure in Solution written by Henry A. Havel and published by VCH Publishers. This book was released on 1996 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultraviolet Resonance Raman Studies of Fast Protein Dynamics Initiated by Microsecond Mixing written by Íñigo Rafael Rodríguez Mendieta and published by . This book was released on 2005 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Deep Ultraviolet Resonance Raman Spectroscopy of Membrane Proteins written by Christopher Halsey and published by . This book was released on 2012 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultraviolet Resonance Raman Spectroscopic Studies of Nucleic Acids and Proteins written by Christine Anne Grygon and published by . This book was released on 1989 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Resonance Raman Spectra of Polyenes and Aromatics written by Thomas G. Spiro and published by Wiley-Interscience. This book was released on 1987 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Masters Theses in the Pure and Applied Sciences written by Wade H. Shafer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Masters Theses in the Pure and Applied Sciences was first conceived, published, and disseminated by the Center for Information and Numerical Data Analysis and Synthesis (CINDAS) * at Purdue University in 1957, starting its coverage of theses with the academic year 1955. Beginning with Volume 13, the printing and dissemination phases of the activity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all con cerned if the printing and distribution of the volumes were handled by an interna tional publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Cor poration of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 34 (thesis year 1989) a total of 13,377 theses titles from 26 Canadian and 184 United States universities. We are sure that this broader base for these titles reported will greatly enhance the value of this important annual reference work. While Volume 34 reports theses submitted in 1989, on occasion, certain univer sities do report theses submitted in previous years but not reported at the time.
Download or read book Monitoring Membrane Protein Structural Changes and Interactions Via Deep UV Resonance Raman Spectroscopy written by Mia C. Brown and published by . This book was released on 2015 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane proteins perform a variety of functions within our cells. They transport nutrients and waste across the lipid barrier, transmit signals from one part of the body to another, and run our immune system. However, despite their ubiquitous and vital presence in all organisms, relatively little is known about this class of proteins compared to their soluble counterparts. In this work I have set out to use deep UV resonance Raman (DUVRR) spectroscopy to characterize structural and environmental transitions of proteins and applied the results to studies involving intramembrane proteases and their substrates. DUVRR has been used extensively to observe protein secondary structure. This work contains the results of three main studies I have conducted during my graduate career. In the first I show results from the first experiment to look simultaneously at both secondary and tertiary structure as a protein transitions from a molten globule to ordered state. In the second study tracks the structural and environmental changes of a small peptide as it transitions from a soluble, disordered state through two membrane-bound, structurally ordered states. I was then able to apply the findings of these experiments to study intramembrane proteolysis, wherein I describe substrate characteristics and their interactions with proteases.
Download or read book Resonance Raman Studies of Small Conjugated Diene Molecules in the Far Ultraviolet written by Gary David Strahan and published by . This book was released on 1989 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Protein Structure written by Robert Austin and published by Springer. This book was released on 2014-11-14 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is concerned with the physical aspects of molecular and electronic tunneling in biological systems, and the extent to which protein structure controls these events. The scope is very broad and this volume could almost be a textbook in biophysics. Both fundamental processes and the extrapolation to physiological events are stressed. The discussion sections are remarkably frank and offer insight into the basic problems confronting physists and chemists as they seek to apply their techniques to biological systems. This book on the physics of biomolecules reflects recent progress in understanding the biological function of the key protein molecules from detailed knowledge of their physics. New and exciting are the glasslike aspects of protein structures and the discussion of proteins as fractals. Other topics dealt with are low-temperature kinetics and reactivity, structure and charge exchange, and charge separation in photosynthetic reaction centers.
Download or read book Methods in Protein Structure and Stability Analysis Vibrational spectroscopy written by Vladimir N. Uversky and published by Nova Publishers. This book was released on 2007 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein research is a frontier field in science. Proteins are widely distributed in plants and animals and are the principal constituents of the protoplasm of all cells, and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and serve as enzymes, structural elements, hormones, immunoglobulins, etc., and are involved throughout the body, and in photosynthesis. This book gathers new leading-edge research from throughout the world in this exciting and exploding field of research.
Download or read book Development of Advanced Chemometric Methods for Analysis of Deep ultraviolet Resonance Raman and Circular Dichroism Spectroscopic Data for Protein Secondary Structure Determination written by Olayinka Oshokoya and published by . This book was released on 2015 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Determination of protein secondary structure ([alpha]-helical, [beta]-sheet, and disordered motifs) has become an area of great importance in biochemistry and biophysics as protein secondary structure is directly related to protein function and protein related diseases. While NMR and x-ray crystallography can predict placement of each atom in proteins to within an angstrom, optical methods (CD, Raman, IR) are the preferred techniques for rapid evaluation of protein secondary structure content. Such techniques require calibration data to predict unknown protein secondary structure content where accuracy may be improved with the application of multivariate analysis. We compare protein secondary structure predictions obtained from multivariate analysis of ultraviolet resonance Raman (UVRR) and circular dichroism (CD) spectroscopic data using classical and partial least squares, and multivariate curve resolution-alternating least squares is made. Based on this analysis, the suggested best approach to rapid and accurate secondary structure determination is a combination of both CD and UVRR spectroscopy.
Download or read book Deep UV Resonance Raman Spectral Properties of Alpha Helical Membrane Proteins written by Anahita Zare and published by . This book was released on 2017 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane protein function and structure determination is vital for pharmaceutical development and disease prevention. Despite the various methods of protein structure elucidation in use, a need still exists for techniques that are of adequate resolution, rapid, inexpensive, and compatible with the membrane environment of these proteins. Deep UV resonance Raman (dUVRR) spectroscopy is an emerging structurally sensitive spectroscopic technique for analyzing membrane protein structure. The backbone amide modes are resonance enhanced in dUVRR spectra while the membrane's lipid features are not, resulting in strong membrane protein spectral features in near native environments. In order to better define dUVRR spectral features of membrane proteins, a series of model helical peptides, poly(LA)7, were designed. By substituting select residues of the transmembrane region of poly(LA)7, the propensity of helical structure within a membrane has also been studied. Using these model membrane peptides in increasingly dehydrated environments (aqueous, surfactant, and bilayer), hydration depended changes in the spectra are characterized.
Download or read book Resonance Raman Studies of Protein cofactor Interactions in Wild Type and Mutant Purple Bacterial Reaction Centers written by Lei Chen and published by . This book was released on 2005 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Advanced Chemometric Methods for the Analysis of Deep UV Resonance Raman Spectra of Proteins written by John Simpson and published by . This book was released on 2009 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultra violet resonance Raman (UVRR) is a powerful spectroscopic technique for determining the secondary structural content of proteins in solution. However, the analyses of UVRR spectra can be problematic due to the difficulty of determining the pure secondary structure Raman spectra. The use of multi-excitation datasets can help to alleviate the difficulty in determining the pure secondary structure Raman spectra, but due to increasing spectral resolution as excitation wavelength increases, multi-excitation datasets are notoriously difficult to align spectral features. In addition, the subtraction of the water band can be difficult when relying on an internal intensity standard. To address these difficulties we demonstrate the use of a series of chemometric methods. To determine the pure secondary structure Raman spectra, we demonstrate the use of multivariate curve resolution using the alternating least squares algorithm (MCRALS) with a multi-excitation data set. To alleviate mis-alignment in multi-excitation data, we demonstrate the use of correlation optimized warping (COW). We also propose a new water band subtraction method which will reliably determine the water band concentration and remove it, without an over subtraction. Finally, we demonstrate the use of parallel factor analysis (PARAFAC) for the characterization of the behavior of the flavonoid quercetin in solution with the protein bovine serum albumin.
