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EBookClubs

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Book Prominin 1  CD133   New Insights on Stem   Cancer Stem Cell Biology

Download or read book Prominin 1 CD133 New Insights on Stem Cancer Stem Cell Biology written by Denis Corbeil and published by Springer Science & Business Media. This book was released on 2012-11-19 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​​​​​​​Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.

Book Master s Theses Directories

Download or read book Master s Theses Directories written by and published by . This book was released on 2007 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Education, arts and social sciences, natural and technical sciences in the United States and Canada".

Book Comparative Molecular Neurobiology

Download or read book Comparative Molecular Neurobiology written by Y. Pichon and published by Birkhäuser. This book was released on 2013-03-08 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is generally accepted that all living organisms present on earth derive from one single primordial cell born several billion years ago. One important step in the evolution occurred some 1. 5 billion years ago with the transition from small procaryote cells with relatively simple internal structures such as bacteria to larger and more compleX: eucaryotic cells such as those found in higher animals and plants. Large membrane proteins which enable the cells to communicate appeared early in evolution, and it is believed that the nerve membrane receptors and ionic channels which are observed today in both invertebrate and vertebrate species derive from a common ancestor. Basically, the three identified superfamilies, 1) ionotropic receptors (i. e. receptors containing an integral ionic channel), 2) metabotropic receptors (receptors coupled to G proteins) and 3) voltage-dependent ionic channels (Na+, K + and Ca2+ channels) were already well differentiated when vertebrates separated from invertebrate species. The large number of subtypes which are observed in each superfamily may be of more recent evolutionary origin. To understand how this happened, the best approach was to compare the sequences and the properties of the receptors and ionic channels in species sufficiently distant in the evolutionary tree. In the present volume, many of the best specialists in the field of comparative molecular neurobiology, several of them working on vertebrate and invertebrate species, have accepted to report their most recent findings.

Book Noncanonical Amino Acids

Download or read book Noncanonical Amino Acids written by Edward A. Lemke and published by . This book was released on 2018 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Germline Development

    Book Details:
  • Author : Joan Marsh
  • Publisher : John Wiley & Sons
  • Release : 1994-08-16
  • ISBN :
  • Pages : 344 pages

Download or read book Germline Development written by Joan Marsh and published by John Wiley & Sons. This book was released on 1994-08-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects classical cellular descriptive studies with more recent work on the molecular and genetic aspects regarding germline development. Prominent scientists discuss research on a range of organisms including insects, worms, birds, fish, amphibia, mammals and green algae. Specification of germ cells, their migration to the gonads and subsequent interactions with the soma and evolutionary factors of their segregation are among the topics covered.

Book Emerging Model Organisms

Download or read book Emerging Model Organisms written by and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume leading experts provide chapters on 23 emerging model systems, ranging from bat and butterfly to cave fish and choanoflagellates; cricket and finch to quail, snail and tomato.

Book Systems Genetics

    Book Details:
  • Author : Florian Markowetz
  • Publisher : Cambridge University Press
  • Release : 2015-07-02
  • ISBN : 131638098X
  • Pages : 287 pages

Download or read book Systems Genetics written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.

Book Computer Graphics 82

Download or read book Computer Graphics 82 written by and published by . This book was released on 1982 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shows How Computer Graphics Can Be Applied to the Communication & Presentation of Business Information. Reviews the Latest Hardware & Software; Covers the Traditional Areas CAD & Modeling Techniques; Explores Design in Computer Graphics; Also Covers Animation & Applications in the Media

Book The Ancient Genes

    Book Details:
  • Author : ReincarnatedSaint
  • Publisher : WWW.WEBNOVEL.COM (Cloudary Holdings Limited)
  • Release : 2020-08-31
  • ISBN :
  • Pages : 509 pages

Download or read book The Ancient Genes written by ReincarnatedSaint and published by WWW.WEBNOVEL.COM (Cloudary Holdings Limited). This book was released on 2020-08-31 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a place where Magic reigns supreme, what would our MC do as he finds himself being rejected by the world. This is the story of a boy who is lacks the ability to wield mana. After shaming his parents who are considered to be among the strongest Mages of the era. Our MC stands at the terrace of the School building planning to commit suicide. What has fate got stored in for our MC. Will he commit suicide ? If you want to know, join our MC as he struggles to find his path. In a world with mysteries and threats looming, what is waiting for him? ------------------------------------- All the characters and incidents in this story are imaginary. Please note that the chapter can be a bit slow. So please be a bit patient and read up to 50 chapter before making any opinion .......................... The Cover art is made by Valeriexx. And is currently being edited by Devrish. He has been a great help to me. Join the Discord : https://discord.gg/WTDaPfU DM me @ ReincarnatedSaint#2904 on Discord Instagram ID: @reincarnatedsaint

Book Pathophysiology of the Kidney

Download or read book Pathophysiology of the Kidney written by Neil A. Kurtzman and published by Charles C. Thomas Publisher. This book was released on 1977 with total page 1114 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Essential Zebrafish Methods  Genetics and Genomics

Download or read book Essential Zebrafish Methods Genetics and Genomics written by H. William Detrich III and published by Academic Press. This book was released on 2009-09-05 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. While genetically distant from humans, nonetheless the vertebrate zebrafish has comparable organs and tissues that make it the model organism for study of vertebrate development.This book, one of two new volumes in the Reliable Lab Solutions series dealing with zebrafish, brings together a robust and up-to-date collection of time-tested methods presented by the world’s leading scientists. Culled from previously published chapters in Methods in Cell Biology and updated by the original authors where relevant, it provides a comprehensive collection of protocols describing the most widely used techniques relevant to the study of zebrafish genetics and genomics. The methods in this volume were hand-selected by the editors, whose goal was to a provide a handy and cost-effective collection of fail-safe methods, tips, and "tricks of the trade" to both experienced researchers and more junior members in the lab. Provides busy researchers a quick reference for time-tested methods and protocols that really work, updated where possible by the original authors Gives pragmatic wisdom to the non-specialist from experts in the field with years of experience with trial and error

Book Pathophysiology of Cardiovascular Disease

Download or read book Pathophysiology of Cardiovascular Disease written by Naranjan S. Dhalla and published by Springer. This book was released on 2012-10-31 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.

Book Neurological and Psychiatric Disorders

Download or read book Neurological and Psychiatric Disorders written by Frank I. Tarazi and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, systematic, and advanced review of the scientific, preclinical, and clinical aspects of several major mental illnesses. The illnesses covered range from neurological disorders including Alzheimer's disease, Huntington's disease, and Parkinson's disease, to psychiatric disorders including schizophrenia, autism spectrum disorders, Tourette's syndrome and tic disorders, obsessive-compulsive disorder, unipolar depression, bipolar disorder, and attention deficit hyperactivity disorder. For each disorder, the authors uniformly discuss its incidence and prevalence, etiology, molecular targets and mechanisms of action, brain structures and pathways, animal models, signs and symptoms, genetics, treatments, and related medical terminology.

Book Renal and Metabolic Disorders

Download or read book Renal and Metabolic Disorders written by John A. Kellum and published by Oxford University Press, USA. This book was released on 2013-02-07 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a road map of the interactions among metabolic, electrolyte, acid-base and endocrine problems and suggesting clear lines of action for the ICU clinician. Each chapter provides guidelines for understanding "how did we get here" and "what should we do now", as quickly and safely as possible.