Download or read book Exploring the Structural and Functional Organization of the Dorsal Zone of Auditory Cortex in Hearing and Deafness written by Melanie A. Kok and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent neuroscientific research has focused on cortical plasticity, which refers to the ability of the cerebral cortex to adapt as a consequence of experience. Over the past decade, an increasing number of studies have convincingly shown that the brain can adapt to the loss or impairment of a sensory system, resulting in the expansion or heightened ability of the remaining senses. A particular region in cat auditory cortex, the dorsal zone (DZ), has been shown to mediate enhanced visual motion detection in deaf animals. The purpose of this thesis is to further our understanding of the structure and function of DZ in both hearing and deaf animals, in order to better understand how the brain compensates following insult or injury to a sensory system, with the ultimate goal of improving the utility of sensory prostheses. First, I demonstrate that the brain connectivity profile of animals with early- and late-onset deafness is similar to that of hearing animals, but the projection strength to visual brain regions involved in motion processing increases as a consequence of deafness. Second, I specifically evaluate the functional impact of the strongest auditory connections to area DZ using reversible deactivation and electrophysiological recordings. I show that projections that ultimately originate in primary auditory cortex (A1) form much of the basis of the response of DZ neurons to auditory stimulation. Third, I show that almost half of the neurons in DZ are influenced by visual or somatosensory information. I further demonstrate that this modulation by other sensory systems can have effects that are opposite in direction during different portions of the auditory response. I also show that techniques that incorporate the responses of multiple neurons, such as multi-unit and local field potential recordings, may vastly overestimate the degree to which multisensory processing occurs in a given brain region. Finally, I confirm that individual neurons in DZ become responsive mainly to visual stimulation following deafness. Together, these results shed light on the function and structural organization of area DZ in both hearing and deaf animals, and will contribute to the development of a comprehensive model of cross-modal plasticity.
Download or read book The Auditory Cortex written by Jeffery A. Winer and published by Springer Science & Business Media. This book was released on 2010-12-02 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been substantial progress in understanding the contributions of the auditory forebrain to hearing, sound localization, communication, emotive behavior, and cognition. The Auditory Cortex covers the latest knowledge about the auditory forebrain, including the auditory cortex as well as the medial geniculate body in the thalamus. This book will cover all important aspects of the auditory forebrain organization and function, integrating the auditory thalamus and cortex into a smooth, coherent whole. Volume One covers basic auditory neuroscience. It complements The Auditory Cortex, Volume 2: Integrative Neuroscience, which takes a more applied/clinical perspective.
Download or read book The Functional Organization of the Auditory System written by Monica Muñoz-Lopez and published by Frontiers Media SA. This book was released on 2017-02-07 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook comprises s series of original research and review articles dealing with the anatomical, genetic, and physiological organization of the auditory system from humans to monkeys and mice.
Download or read book Auditory Cortex written by L.M. Aitkin and published by Springer. This book was released on 1990-07-31 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This account of the auditory cortex brings together research in the various disciplines of neuroscience. Its purpose is to give the reader an adequate background for understanding the mechanisms of normal auditory cortical function and cortical deafness. It is designed to inform readers with a variety of backgrouds, including physiologists, anatomists, psychologists and neurologists. To this end the terminology needed to express ideas about auditory cortical structure and function is related to a chapter in which methodology is stressed.
Download or read book The Human Auditory Cortex written by David Poeppel and published by Springer Science & Business Media. This book was released on 2012-04-12 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: We live in a complex and dynamically changing acoustic environment. To this end, the auditory cortex of humans has developed the ability to process a remarkable amount of diverse acoustic information with apparent ease. In fact, a phylogenetic comparison of auditory systems reveals that human auditory association cortex in particular has undergone extensive changes relative to that of other species, although our knowledge of this remains incomplete. In contrast to other senses, human auditory cortex receives input that is highly pre-processed in a number of sub-cortical structures; this suggests that even primary auditory cortex already performs quite complex analyses. At the same time, much of the functional role of the various sub-areas in human auditory cortex is still relatively unknown, and a more sophisticated understanding is only now emerging through the use of contemporary electrophysiological and neuroimaging techniques. The integration of results across the various techniques signify a new era in our knowledge of how human auditory cortex forms basis for auditory experience. This volume on human auditory cortex will have two major parts. In Part A, the principal methodologies currently used to investigate human auditory cortex will be discussed. Each chapter will first outline how the methodology is used in auditory neuroscience, highlighting the challenges of obtaining data from human auditory cortex; second, each methods chapter will provide two or (at most) three brief examples of how it has been used to generate a major result about auditory processing. In Part B, the central questions for auditory processing in human auditory cortex are covered. Each chapter can draw on all the methods introduced in Part A but will focus on a major computational challenge the system has to solve. This volume will constitute an important contemporary reference work on human auditory cortex. Arguably, this will be the first and most focused book on this critical neurological structure. The combination of different methodological and experimental approaches as well as a diverse range of aspects of human auditory perception ensures that this volume will inspire novel insights and spurn future research.
Download or read book The Auditory Cortex written by Peter Heil and published by Psychology Press. This book was released on 2005-05-06 with total page 929 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding human hearing is not only a scientific challenge but also a problem of growing social and political importance, given the steadily increasing numbers of people with hearing deficits or even deafness. This book is about the highest level of hearing in humans and other mammals. It brings together studies of both humans and animals thereby giving a more profound understanding of the concepts, approaches, techniques, and knowledge of the auditory cortex. All of the most up-to-date procedures of non-invasive imaging are employed in the research that is described.
Download or read book Reorganization of Auditory Cortex in Deaf People written by Martha Shiell and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "After early deafness, the brain can reorganize so that the sensory-deprived auditory cortex processes visual information. This cross-modal activity has been demonstrated numerous times in functional brain imaging research, but we still know little about the underlying mechanisms, the factors that constrain it, and its behavioural consequences. In this thesis, we address these unknowns in three studies that examine the functional, behavioural, and anatomical correlates of cross-modal reorganization in early-deaf adults. In study one, we used functional magnetic resonance imaging to identify cross-modal activity in the posterior superior temporal cortex of deaf people. With functional connectivity analysis, we explored the cortical network of this reorganized area and found enhanced interactions with primary visual cortex. Here, both the amplitude of the cross-modal activity and the strength of the audio-visual functional connectivity correlated with residual hearing, as measured by duration of hearing aid use: deaf people with more residual hearing showed less cross-modal reorganization. This study gives insight into the mechanism of cross-modal plasticity after deafness, revealing that it involves a network-level change and that it varies with the degree of auditory deprivation over the lifetime. In study two, we hypothesized that auditory deprivation causes compensatory changes to vision, and predicted that this would manifest as an improved ability in deaf people to detect visual motion. We designed a visual psychophysical test, which determined that people with early and profound deafness have lower motion detection thresholds than hearing controls. In study three, we followed up on the effect of study two, with the hypothesis that enhanced vision in deaf people is supported by cross-modal reorganization of auditory cortex. We measured cortical thickness with magnetic resonance imaging in early and profoundly deaf people, and found a correlation between visual motion detection thresholds and the thickness of the right posterior superior temporal cortex. This correlation implicates this area in compensatory vision and indicates an anatomical correlate - increased cortical thickness - of cross-modal plasticity. Based on the findings of these three studies, we conclude that cross-modal activity and increased cortical thickness in the right superior temporal cortex of deaf people reflect increased visual input to this area, and that these adaptations support enhanced visual motion detection, perhaps for sensory reorienting. We suggest that this plasticity may occur as a result of decreased activity-driven pruning after early auditory deprivation, and that it is interrupted when individuals exploit their residual hearing. This work illuminates the principles that govern cortical plasticity, and informs us on the organization and function of the right posterior superior temporal cortex." --
Download or read book The Central Auditory System written by Günter Ehret and published by Oxford University Press, USA. This book was released on 1997 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a graduate-level text on the neurobiology of hearing, covering the structure and function of the central auditory pathway of all mammals.
Download or read book Association and Auditory Cortices written by Alan Peters and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume deals with some of the association areas of the cerebral cortex and with the auditory cortex. In the first chapter, by Deepak Pandya and Edward Yeterian, the general architectural features and connections of cortical associ ation areas are considered; as these authors point out, in primates the association areas take up a considerable portion of the total cortical surface. Indeed, it is the development of the association areas that accounts for the greatest differ ences between the brains of primate and non primate species, and these areas have long been viewed as crucial in the formation of higher cognitive and be havioral functions. In the following chapter, Irving Diamond, David Fitzpatrick, and James Sprague consider the question of whether the functions of the as sociation areas depend on projections from the sensory areas of the cortex. They use the visual cortex to examine this question and show that there is a great deal of difference between species in the amount of dependence, the differences being paralleled by variations in the manner in which the geniculate and pulvinar nuclei of the thalamus project to the striate and extra striate cortical areas. One of the more interesting and perhaps least understood of the association areas is the cingulate cortex, discussed by Brent Vogt. Cingulate cortex has been linked with emotion and with affective responses to pain, and in his chapter Vogt gives an account of its cytoarchitecture, connections, and functions.
Download or read book Neuronal Mechanisms of Hearing written by Lindsay Aitkin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to the level of interest which is paid to the orga nization of meetings about the structure and function of the audi tory periphery, the central auditory system has received little attention in the last several years. However, much recent data accu mulated during this period has provided auditory physiologists with new ideas about the function of the central auditory system. The successful exploration of new anatomical tracing techniques (triti ated aminoacids, horseradish peroxidase, 2-deoxyglucose) together with the collection of electrophysiological data obtained with intra cellular and extracellular recordings from the receptors and neurones in the auditory pathway have considerably deepened our understanding of central auditory function. Particular interest was concentrated upon the development of the auditory system under normal conditions and in conditions ofaudi tory deprivation. Although, from the methodological point of view, the conditions of reversible auditory deprivation are complicated, promising new data appeared in this field. Similarly the specific ability of the auditory system to encode communication signals and speech sounds has been examined in many laboratories allover the world. A very fruitful method. based upon the results of electrical stimulation of cochlear nerve fibres in experimental animals, is the application of neuroprostheses in deaf patients. At the present time, the method still does not meet all requirements and many improvements will be necessary. Undoubtedly the exploration of the results of recent physiological experiments may help in the further improvement of neuroprostheses.
Download or read book The Human Auditory System written by Gastone G. Celesia and published by Elsevier. This book was released on 2015-03-06 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Human Auditory System: Fundamental Organization and Clinical Disorders provides a comprehensive and focused reference on the neuroscience of hearing and the associated neurological diagnosis and treatment of auditory disorders. This reference looks at this dynamic area of basic research, a multidisciplinary endeavor with contributions from neuroscience, clinical neurology, cognitive neuroscience, cognitive science communications disorders, and psychology, and its dramatic clinical application. - A focused reference on the neuroscience of hearing and clinical disorders - Covers both basic brain science, key methodologies and clinical diagnosis and treatment of audiology disorders - Coverage of audiology across the lifespan from birth to elderly topics
Download or read book Auditory Function written by Gerald M. Edelman and published by Wiley-Interscience. This book was released on 1988 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in anatomical, physiological, and psychophysical techniques and new formal analyses have made considerable advances in integrating the various aspects of hearing.
Download or read book The Functional Organization of the Auditory System written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook comprises s series of original research and review articles dealing with the anatomical, genetic, and physiological organization of the auditory system from humans to monkeys and mice.
Download or read book Evolution of Nervous Systems written by Georg F. Striedter and published by Academic Press. This book was released on 2016-11-23 with total page 2064 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution of Nervous Systems, Second Edition, Four Volume Set is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike. Presents a broad range of topics, ranging from genetic control of development in invertebrates, to human cognition, offering a one-stop resource for the evolution of nervous systems throughout the animal kingdom Incorporates the expertise of over 100 outstanding investigators who provide their conclusions in the context of the latest experimental results Presents areas of disagreement and consensus views that provide a holistic view of the subjects under discussion
Download or read book Stroke Syndromes 3ed written by Louis R. Caplan and published by Cambridge University Press. This book was released on 2012-07-12 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of dysfunction due to stroke, this revised edition remains the definitive guide to stroke patterns and syndromes.
Download or read book Development of the Auditory System written by Edwin W. Rubel and published by Springer. This book was released on 2011-10-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this volume have provided a detailed and integrated introduction to the behavioural, anatomical, and physiological changes that occur in the auditory system of developing animals. Edwin W Rubel is Virginia Merrill Bloedel Professor of Hearing Sciences at the Virginia Merrill Bloedel Hearing Research Center at the University of Washington, Arthur N. Popper is Professor and Chair of the Department of Zoology at the University of Maryland, while Richard R. Fay is Associate Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago. Each volume in this series is independent and authoritative; taken as a set, the series will be the definitive resource in the field.
Download or read book The Behavioral and Cognitive Neurology of Stroke written by Olivier Godefroy and published by Cambridge University Press. This book was released on 2007-01-18 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: The care of stroke patients has changed dramatically. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioural and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management and the likelihood and significance of long-term disability. This book will appeal to all clinicians involved in the care of stroke patients, as well as to neuropsychologists, other rehabilitation therapists and research scientists investigating the underlying neuroscience.
