Download or read book Exploration of Interaction Between Plasmodium Falciparum Hsp70 x PfHsp70 x and Human Hsp70 Hsp90 Organizing Protein human Hop written by Blessing Mabate and published by . This book was released on 2017 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Characterization of the Hsp70 Hsp90 Organizing Protein Hop written by Sheril Daniel and published by . This book was released on 2012 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In silico Analysis of Plasmodium Falciparum Hop Protein and Its Interactions with Hsp70 and Hsp90 written by Crystal-Leigh Clitheroe and published by . This book was released on 2013 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Heat Shock Proteins of Malaria written by Addmore Shonhai and published by Springer Nature. This book was released on 2021-09-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular parasite stages. Thoroughly revised, this work provides a general introduction to the structural and functional features of heat shock proteins with a special focus on their role as molecular chaperones in ensuring protein quality control. The emphasis is on the heat shock protein families from Plasmodium falciparum, and their role in proteostasis and the development of malaria pathology. Moreover, the authors explore the latest prospects of targeting heat shock proteins in antimalarial drug discovery either directly or in combination therapies. Readers will experience a functional analysis of the individual families of heat shock proteins and their cooperation in functional networks, including both the parasite-resident proteome and the exportome released into host cells during intracellular stages. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts associated with Plasmodium species are discussed in detail. The book highlights the role of heat shock proteins in the development and function of these structures. Biochemical expertise and the inclusion of novel therapeutic solutions make this collection a unique reference for experts in heat shock protein research, parasitology and infectious diseases, cell stress, molecular biology and drug discovery. Not least, advances in malaria control will contribute to ending epidemics and ensuring healthy lives in line with the UN Sustainable Development Goals.
Download or read book Establishment of Interaction Partners of Plasmodium Falciparum Heat Shock Protein 70 x PfHsp70 x written by Florina Semakaleng Monyai and published by . This book was released on 2018 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antimalarial Chemotherapy written by Philip J. Rosenthal and published by Springer Science & Business Media. This book was released on 2001-04-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.
Download or read book The Dream House written by Craig Higginson and published by Pan Macmillan South africa. This book was released on 2016-04-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: A farmhouse is being reproduced a dozen times, with slight variations, throughout a valley. Three small graves have been dug in the front garden, the middle one lying empty. A woman in a wheelchair sorts through boxes while her husband clambers around the old demolished buildings, wondering where the animals have gone. A young woman – called ‘the barren one’ behind her back – dreams of love, while an ageing headmaster contemplates the end of his life. At the entrance to the long dirt driveway, a car appears and pauses – pointed towards the house like a silver bullet, ticking with heat. So begins The Dream House, Craig Higginson’s riveting and unforgettable novel set in the Midlands of KwaZulu-Natal. Written with dark wit, a stark poetic style and extraordinary tenderness, this is a story about the state of a nation and a deep meditation on memory, ageing, meaning, family, love and loss. This updated 2016 edition contains new content, with Craig Higginson exploring the background to The Dream House, his varied experiences in a farmhouse in KwaZulu-Natal and the subsequent and poignant motivations for this moving novel.
Download or read book The Geometry of Violence written by Leonhard Praeg and published by AFRICAN SUN MeDIA. This book was released on 2007-09-01 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: ?[Praeg] applies the notion of ?sacrificial violence?, as developed by Girard, to the genocide in Rwanda, necklace burnings in South Africa, and the phenomenon of family murders. He shows how there is an underlying logic tying these together, while at the same time resisting a unifying (modernist) discourse which attempts to eradicate the differences. This is an extremely interesting, at times fascinating, text. It is very well written and ... [the] insights gained leave no option but to rethink the manifestation of violence fundamentally.? ? Paul Cilliers Department of Philosophy, Stellenbosch University
Download or read book AIDS Intimacy and Care in Rural KwaZulu Natal written by Patricia C. Henderson and published by Amsterdam University Press. This book was released on 2011 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how HIV/AIDS became part of the lives of the people of the mountainous Okhahlamba in the South African province of KwaZulu-Natal. Based on extensive research in the area between 2003 and 2006, the author shows what impact the disease had - and still does - for adults and children, and the different ways people tried to find answers to the devastating presence of HIV / AIDS. Henderson focuses on informal care by family members and volunteers at a time when anti-retroviral drugs were not yet available. She also shows what it meant to the community once the drugs became available.
Download or read book Molecular Chaperones in the Cell written by Peter A. Lund and published by Oxford University Press, USA. This book was released on 2001 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this text, leading experts synthesise our body of knowledge , and the reader gains not only a fuller understanding of the roles of chaperones in the context of cellular processes, but also an insight into the nature of these proteins.
Download or read book First Steps in Research written by Kobus Maree and published by . This book was released on 2019 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A theoretical and practical guide on how to conduct and report on research at undergraduate and postgraduate level. Uses the most current perspectives in the field; both locally and internationally; to facilitate the understanding and application of theories; goals; methods and strategies. Aimed at scholars; academics; researchers; and Master's and doctoral students who are conceptualising and conducting research
Download or read book Antjie Krog and the Post Apartheid Public Sphere written by Anthea Garman and published by University of Kwazulu Natal Press. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antjie Krog has been known in Afrikaans literary circles and the media for decades because of her poetry and her strong political convictions. Often known simply as 'Antjie, ' she is also affectionately called 'our beloved poet' and our 'Joan of Arc' by Afrikaans commentators. It was through her work on the Truth and Reconciliation Commission as an SABC radio journalist and her subsequent book, Country of My Skull, that Antjie Krog then became known to English-speakers in South Africa and across the world. Her work catapulted her particular brand of poetics and politics, honed over many years of her opposition to apartheid, into the South African public sphere at a time when the country was not only looking for a humane and just resolution after the apartheid era, but was also establishing itself as a new democracy. These were heady days as South Africa discovered an exciting place in the world, as the country realized it had things to say and teach about race, conflict, and justice. It was also a time when the new government was seeking solutions and urging all those who could contribute positively to stand up and speak out. The language of 'public intellectuals' was in the air. This book considers how Antjie Krog - the prolific poet, journalist, non-fiction author, academic, and researcher - has made a significant contribution to the South African post-apartheid public sphere. Krog's inimitable style, rooted in her sensibility as a poet, has allowed her to develop a particular persona and subjectivity as a writer of testimony and witness. [Subject: Politics, African Studies, Apartheid Studies, Literature
Download or read book Wish to Live written by Ruth Nicole Brown and published by Peter Lang Incorporated, International Academic Publishers. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intergenerational account capturing the contemporary politics and poetics of hip-hop feminism.
Download or read book John Solilo written by John Solilo and published by University of Kwazulu Natal Press. This book was released on 2016 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: For 40 years, between 1900 and 1939, John Solilo (1864-1940) was a prolific contributor to Xhosa-language newspapers under his own name and under the pseudonyms Mde-ngelimi (Master Wordsmith) and Kwanguye (It's Still Him). He submitted letters and articles on a variety of issues, local news reports from Cradock and Uitenhage, and a considerable body of poetry. Solilo's major literary contribution was his collection of poems entitled Izala, published in 1925, the earliest volume of poetry by a single author in the history of Xhosa literature. His poetry was inspired by umoya wembongi, the spirit of the imbongi, the praise poet whose stirring declamations roused his audiences to action or contemplation. Solilo's literary reputation today, however, is at variance with his prominence as a major author in the first four decades of the twentieth century: he is hardly mentioned, if at all, by literary historians. That neglect is perhaps not surprising: Izala has long been out of print, and copies can no longer be located. The present volume is therefore an exercise in reclamation and restitution. In restoring to the public domain the 65 poems that made up Izala and adding an additional 28 that were published in newspapers both before and after the appearance of Izala, the editors hope to revive John Solilo's reputation as a poet, and to establish his status as a pre-eminent Xhosa author. Jeff Opland commenced his academic career as a medievalist, but for the past 40 years he has assembled a collection of oral and printed poetry and has devoted himself to defining and restoring the heritage of literature in the Xhosa language. Amongst other works, with Peter Mtuze he edited two anthologies of Xhosa literature, Isigodlo sikaPhalo (1983) and Izwi labantu (1994). Opland is currently Visiting Professor in the School of Languages: African Language Studies at Rhodes University. Peter T. Mtuze is the most prolific living isiXhosa writer. He has authored and co-authored no fewer than 30 books. His main contribution is in creative writing: he has produced novels, short stories, essays, drama, poetry, autobiography and language books. Mtuze's first book, UDingezweni, which appeared as far back as 1966, is regarded as a classic novel. One of his singular achievements was his translation of former President Nelson Mandela's autobiography, Long Walk to Freedom, into isiXhosa. He worked on the University of Fort Hare Xhosa Dictionary Project, at the University of South Africa and at Rhodes University, where he retired as Professor Emeritus. (Series: Publications of the Opland Collection of Xhosa Literature, Vol. 3) [Subject: Poetry, African Studies]
Download or read book Molecular Aspects of Plant Salinity Stress and Tolerance written by Jen-Tsung Chen and published by MDPI. This book was released on 2021-09-08 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
Download or read book D L P Yali Manisi Imbongi Entsha written by D. L. P. Yali-Manisi and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: David Livingstone Phakamile Yali-Manisi (1926-99) was a Thembu imbongi, the most powerful exponent of the art of praise poetry in the Xhosa language, in the second half of the twentieth century. His literary career, however, was blighted by circumstances beyond his control, and he died in total obscurity. A supporter of the African National Congress, he was the author of the earliest poem in praise of Nelson Mandela (1954).
Download or read book Country of My Skull written by Antjie Krog and published by Crown. This book was released on 2007-12-18 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since Nelson Mandela dramatically walked out of prison in 1990 after twenty-seven years behind bars, South Africa has been undergoing a radical transformation. In one of the most miraculous events of the century, the oppressive system of apartheid was dismantled. Repressive laws mandating separation of the races were thrown out. The country, which had been carved into a crazy quilt that reserved the most prosperous areas for whites and the most desolate and backward for blacks, was reunited. The dreaded and dangerous security force, which for years had systematically tortured, spied upon, and harassed people of color and their white supporters, was dismantled. But how could this country--one of spectacular beauty and promise--come to terms with its ugly past? How could its people, whom the oppressive white government had pitted against one another, live side by side as friends and neighbors? To begin the healing process, Nelson Mandela created the Truth and Reconciliation Commission, headed by the renowned cleric Archbishop Desmond Tutu. Established in 1995, the commission faced the awesome task of hearing the testimony of the victims of apartheid as well as the oppressors. Amnesty was granted to those who offered a full confession of any crimes associated with apartheid. Since the commission began its work, it has been the central player in a drama that has riveted the country. In this book, Antjie Krog, a South African journalist and poet who has covered the work of the commission, recounts the drama, the horrors, the wrenching personal stories of the victims and their families. Through the testimonies of victims of abuse and violence, from the appearance of Winnie Mandela to former South African president P. W. Botha's extraordinary courthouse press conference, this award-winning poet leads us on an amazing journey. Country of My Skull captures the complexity of the Truth Commission's work. The narrative is often traumatic, vivid, and provocative. Krog's powerful prose lures the reader actively and inventively through a mosaic of insights, impressions, and secret themes. This compelling tale is Antjie Krog's profound literary account of the mending of a country that was in colossal need of change.
