Download or read book Experimenting with Humans and Animals written by Anita Guerrini and published by JHU Press. This book was released on 2003-07-02 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethical questions about the use of animals and humans in research remain among the most vexing within both the scientific community and society at large. These often rancorous arguments have gone on, however, with little awareness of their historical antecedents. Experimentation on animals and particularly humans is often assumed to be a uniquely modern phenomenon, but the ideas and attitudes that encourage the biological and medical sciences to experiment on living creatures date from the earliest expression of Western thought. Here, Anita Guerrini looks at the history of these practices from vivisection in ancient Alexandria to present-day battles over animal rights and medical research employing human subjects. Guerrini discusses key historical episodes, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent AIDS research. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy.--From publisher description.

Download or read book The Human Experiment written by Jane Poynter and published by Basic Books. This book was released on 2006-08-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's a story that has never been told … until now. Imagine being sealed into a closed environment for two years — cut off from the outside world with only seven other people — enduring never-ending hunger, severely low levels of oxygen, and extremely difficult relationships. Crew members struggled to survive in Biosphere 2, where they swore nothing would go in or out — no food or water, not even air — all in the name of science. For the first time, biospherian Jane Poynter — who lived and loved in the Biosphere — is ready to share what really happened in there. She takes readers on a riveting, fast-paced trip through shattered lives, scientific discovery, cults, love, fears of insanity, and inspiring human endurance. The eight biospherians who closed themselves into the Biosphere emerged 730 days later… much wiser, thinner, and having done what many had said was impossible.

Download or read book The Uses of Humans in Experiment written by and published by BRILL. This book was released on 2016-03-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethics in human experimentation has a long history and The Uses of Humans in Experiment draws on examples from the early modern period to illustrate how humans have been both subjects and instruments over the past four centuries.

Download or read book Designing Human Practices written by Paul Rabinow and published by University of Chicago Press. This book was released on 2012-05-21 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2006 anthropologists Paul Rabinow and Gaymon Bennett set out to rethink the role that human sciences play in biological research, creating the Human Practices division of the Synthetic Biology Engineering Research Center—a facility established to create design standards for the engineering of new enzymes, genetic circuits, cells, and other biological entities—to formulate a new approach to the ethical, security, and philosophical considerations of controversial biological work. They sought not simply to act as watchdogs but to integrate the biosciences with their own discipline in a more fundamentally interdependent way, inventing a new, dynamic, and experimental anthropology that they could bring to bear on the center’s biological research. Designing Human Practices is a detailed account of this anthropological experiment and, ultimately, its rejection. It provides new insights into the possibilities and limitations of collaboration, and diagnoses the micro-politics which effectively constrained the potential for mutual scientific flourishing. Synthesizing multiple disciplines, including biology, genetics, anthropology, and philosophy, alongside a thorough examination of funding entities such as the National Science Foundation, Designing Human Practices pushes the social study of science into new and provocative territory, utilizing a real-world experience as a springboard for timely reflections on how the human and life sciences can and should transform each other.

Download or read book Biomedical Ethics and the Law written by James M. Humber and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years, an increasing number of colleges and universities have added courses in biomedical ethics to their curricula. To some extent, these additions serve to satisfy student demands for "relevance. " But it is also true that such changes reflect a deepening desire on the part of the academic community to deal effectively with a host of problems which must be solved if we are to have a health-care delivery system which is efficient, humane, and just. To a large degree, these problems are the unique result of both rapidly changing moral values and dramatic advances in biomedical technology. The past decade has witnessed sudden and conspicuous controversy over the morality and legality of new practices relating to abortion, therapy for the mentally ill, experimentation using human subjects, forms of genetic interven tion, and euthanasia. Malpractice suits abound, and astronomical fees for malpractice insurance threaten the very possibility of medical and health-care practice. Without the backing of a clear moral consensus, the law is frequently forced into resolving these conflicts only to see the moral issues involved still hotly debated and the validity of the existing law further questioned. Take abortion, for example. Rather than settling the legal issue, the Supreme Court's original abortion decision in Roe v. Wade (1973), seems only to have spurred further legal debate. And of course, whether or not abortion is a mo rally ac ceptable procedure is still the subject of heated dispute.

Download or read book Experiments in Democracy written by Benjamin J. Hurlbut and published by Columbia University Press. This book was released on 2017-01-31 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human embryo research touches upon strongly felt moral convictions, and it raises such deep questions about the promise and perils of scientific progress that debate over its development has become a moral and political imperative. From in vitro fertilization to embryonic stem cell research, cloning, and gene editing, Americans have repeatedly struggled with how to define the moral status of the human embryo, whether to limit its experimental uses, and how to contend with sharply divided public moral perspectives on governing science. Experiments in Democracy presents a history of American debates over human embryo research from the late 1960s to the present, exploring their crucial role in shaping norms, practices, and institutions of deliberation governing the ethical challenges of modern bioscience. J. Benjamin Hurlbut details how scientists, bioethicists, policymakers, and other public figures have attempted to answer a question of great consequence: how should the public reason about aspects of science and technology that effect fundamental dimensions of human life? Through a study of one of the most significant science policy controversies in the history of the United States, Experiments in Democracy paints a portrait of the complex relationship between science and democracy, and of U.S. society's evolving approaches to evaluating and governing science's most challenging breakthroughs.

Download or read book The Plutonium Files written by Eileen Welsome and published by Delta. This book was released on 2010-10-20 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition.

Download or read book Experimenting with Humans and Animals written by Anita Guerrini and published by JHU Press. This book was released on 2022-08-02 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The author discusses key historical episodes in the use of living beings in experiments in science and medicine. This new edition emphasizes a broader understanding of experimentation and has material on prisoners and slaves as experimental subjects, gene therapy, and self-experimentation"--

Download or read book Experiment and the Making of Meaning written by D.C. Gooding and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: . . . the topic of 'meaning' is the one topic discussed in philosophy in which there is literally nothing but 'theory' - literally nothing that can be labelled or even ridiculed as the 'common sense view'. Putnam, 'The Meaning of Meaning' This book explores some truths behind the truism that experimentation is a hallmark of scientific activity. Scientists' descriptions of nature result from two sorts of encounter: they interact with each other and with nature. Philosophy of science has, by and large, failed to give an account of either sort of interaction. Philosophers typically imagine that scientists observe, theorize and experiment in order to produce general knowledge of natural laws, knowledge which can be applied to generate new theories and technologies. This view bifurcates the scientist's world into an empirical world of pre-articulate experience and know how and another world of talk, thought and argument. Most received philosophies of science focus so exclusively on the literary world of representations that they cannot begin to address the philosophical problems arising from the interaction of these worlds: empirical access as a source of knowledge, meaning and reference, and of course, realism. This has placed the epistemological burden entirely on the predictive role of experiment because, it is argued, testing predictions is all that could show that scientists' theorizing is constrained by nature. Here a purely literary approach contributes to its own demise. The epistemological significance of experiment turns out to be a theoretical matter: cruciality depends on argument, not experiment.

Download or read book Doctors from Hell written by Vivien Spitz and published by Sentient Publications. This book was released on 2005 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chilling story of human depravity and ultimate justice, told for the first time by an eyewitness court reporter for the Nuremberg war crimes trial of Nazi doctors. This is the account of 22 men and 1 woman and the torturing and killing by experiment they authorized in the name of scientific research and patriotism. Doctors from Hell includes trial transcripts that have not been easily available to the general public and previously unpublished photographs used as evidence in the trial. The author describes the experience of being in bombed-out, dangerous, post-war Nuremberg, where she lived for two years while working on the trial. Once a Nazi sympathizer tossed bombs into the dining room of the hotel where she lived moments before she arrived for dinner. She takes us into the courtroom to hear the dramatic testimony and see the reactions of the defendants to the proceedings. This landmark trial resulted in the establishment of the Nuremberg code, which set the guidelines for medical research involving human beings. A significant addition to the literature on World War II and the Holocaust, medical ethics, human rights, and the barbaric depths to which human beings can descend.

Download or read book The Ecology of Human Development written by Urie BRONFENBRENNER and published by Harvard University Press. This book was released on 2009-06-30 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a book that challenges the very basis of the way psychologists have studied child development. According to Urie Bronfenbrenner, one of the world's foremost developmental psychologists, laboratory studies of the child's behavior sacrifice too much in order to gain experimental control and analytic rigor. Laboratory observations, he argues, too often lead to "the science of the strange behavior of children in strange situations with strange adults for the briefest possible periods of time." To understand the way children actually develop, Bronfenbrenner believes that it will be necessary to observe their behavior in natural settings, while they are interacting with familiar adults over prolonged periods of time. This book offers an important blueprint for constructing such a new and ecologically valid psychology of development. The blueprint includes a complete conceptual framework for analysing the layers of the environment that have a formative influence on the child. This framework is applied to a variety of settings in which children commonly develop, ranging from the pediatric ward to daycare, school, and various family configurations. The result is a rich set of hypotheses about the developmental consequences of various types of environments. Where current research bears on these hypotheses, Bronfenbrenner marshals the data to show how an ecological theory can be tested. Where no relevant data exist, he suggests new and interesting ecological experiments that might be undertaken to resolve current unknowns. Bronfenbrenner's groundbreaking program for reform in developmental psychology is certain to be controversial. His argument flies in the face of standard psychological procedures and challenges psychology to become more relevant to the ways in which children actually develop. It is a challenge psychology can ill-afford to ignore.

Download or read book For the Good of Mankind written by Vicki Oransky Wittenstein and published by Twenty-First Century Books. This book was released on 2013-08-01 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiment: A child is deliberately infected with the deadly smallpox disease without his parents' informed consent. Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Incidents like these paved the way for crucial, lifesaving medical discoveries. But they also harmed and humiliated their test subjects. How do doctors balance the need to test new medicines and procedures with their ethical duty to protect the rights of humans? Take a journey through some of history's greatest medical advances—and its most horrifying medical atrocities—to discover how human suffering has gone hand in hand with medical advancement.

Download or read book Acres of Skin written by Allen M. Hornblum and published by Routledge. This book was released on 2013-05-13 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time of increased interest and renewed shock over the Tuskegee syphilis experiments, Acres of Skin sheds light on yet another dark episode of American medical history. In this disturbing expose, Allen M. Hornblum tells the story of Philadelphia's Holmesburg Prison.

Download or read book When Experiments Travel written by Adriana Petryna and published by Princeton University Press. This book was released on 2009-04-27 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil, When Experiments Travel documents the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets. Providing a unique perspective on globalized clinical trials, When Experiments Travel raises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today. When Experiments Travel challenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.

Download or read book In the Name of Science written by Andrew Goliszek and published by St. Martin's Press. This book was released on 2003-11-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, as Andrew Goliszek proves in this compendious, chilling, and eye-opening book, has always had its dark side. Behind the bright promise of life-saving vaccines and life-enhancing technologies lies the true cost of the efforts to develop them. Knowledge has a price; often that price has been human suffering. The ethical limits governing use of the human body in experimentation have been breached, redefined, and breached again---from the moment the first plague-ridden corpse was heaved over the fortifications of a besieged medieval city to the use of cutting-edge gene therapy today. Those limits are in constant need of redefinition, for the goals and the techniques have become both more refined and more secretive. The German and Japanese human experiments of the 1930s and 1940s horrified the world when they came to light. These barbaric exercises in pseudoscience grew out of assumptions of racial superiority. The subjects were deemed subhuman; ordinary guidelines could therefore be suspended. What has happened in the decades since World War II has differed only in degree. Explicitly or implicitly, any organization or government that undertakes or sponsors scientific research applies some measure of human worth. Experimentation rests upon an equation that balances suffering against gain, the good of the collective against the rights of the individual, and the risk of unknown consequences against the rewards of scientific discovery. Everything depends upon who makes that equation. The sobering and gripping accumulation of evidence in this book proves exactly what has been justified in the name of science. The science of "eugenics" justified enforced sterilization. The need to gain an upper hand in the Cold War justified CIA experiments involving mind control and drugs. The desperate race to control nuclear proliferation was used to justify radiation experiments whose effects are still being felt today. Chemical warfare, gene therapy, molecular medicine: These subjects dominate headlines and even direct our government's foreign policy, yet the whole truth about the experimentation behind them has never been made public. Though not a cheering book, In the Name of Science is a crucially important one, and it deserves a wide audience. A biologist by training, Goliszek presents each topic clearly and explains fully its significance and implications. Connecting the history of scientific experimentation through time with the topics that are likely to dominate the future, he has performed an invaluable service. No other book on the market provides the research included here, or presents it with such persuasive force.

Download or read book Ethics by Committee written by Noortje Jacobs and published by University of Chicago Press. This book was released on 2022-08-26 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Ethics boards have become obligatory passage points in today's medical science, and we forget how novel they really are. The use of humans in experiments is an age-old practice that records show goes back to at least the third century BC and, since the early modern period, as a practice it has become increasingly popular. Yet, in most countries around the world, hardly any formal checks and balances existed to govern the communal oversight of experiments involving human subjects until at least the 1960s. Ethics by Committee traces the rise of ethics boards for human experimentation in the second half of the twentieth century. Using the Netherlands as a case-study, Noortje Jacobs shows how the authority of physicians to make decisions about clinical research gave way in most developed nations to formal mechanisms of communal decision-making that served to regiment the behavior of individual researchers. This historically unprecedented change in scientific governance came out of a growing international wariness of medical research in the decades after World War II. Research ethics committees were originally intended not only to make human experimentation more ethical but also to raise its epistemic quality. By examining complex negotiations over the appropriate governance of human subjects research, Ethics by Committee advances our understanding not only of the history of research ethics and the randomized controlled trial but also, more broadly, of how liberal democracies in the late twentieth century have sought to resolve public concerns over charged issues in medicine and science"--

Download or read book Scarlet Experiment written by Jeff Karnicky and published by U of Nebraska Press. This book was released on 2016-11-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emily Dickinson's poem "Split the Lark" refers to the "scarlet experiment" by which scientists destroy a bird in order to learn more about it. Indeed, humans have killed hundreds of millions of birds--for science, fashion, curiosity, and myriad other reasons. In the United States alone, seven species of birds are now extinct and another ninety-three are endangered. Conversely, the U.S. conservation movement has made bird-watching more popular than ever, saving countless bird populations; and while the history of actual physical human interaction with birds is complicated, our long aesthetic and scientific interest in them is undeniable. Since the beginning of the modern conservation movement in the mid-nineteenth century, human understanding of and interaction with birds has changed profoundly. In Scarlet Experiment, Jeff Karnicky traces the ways in which birds have historically been seen as beautiful creatures worthy of protection and study and yet subject to experiments--scientific, literary, and governmental--that have irrevocably altered their relationship with humans. This examination of the management of bird life in America from the nineteenth century to today, which focuses on six bird species, finds that renderings of birds by such authors as Henry David Thoreau, Emily Dickinson, Don DeLillo, and Christopher Cokinos, have also influenced public perceptions and actions. Scarlet Experiment speculates about the effects our decisions will have on the future of North American bird ecology.