Download or read book Landmark Experiments in Molecular Biology written by Michael Fry and published by Academic Press. This book was released on 2016-06-10 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling

Download or read book Experimental Design for Biologists written by David J. Glass and published by CSHL Press. This book was released on 2007 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.

Download or read book Experimental Design for Laboratory Biologists written by Stanley E. Lazic and published by Cambridge University Press. This book was released on 2016-12-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Download or read book Developmental Biology written by Mary S. Tyler and published by Sinauer Associates, Incorporated. This book was released on 1994 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Collecting Experiments written by Bruno J. Strasser and published by University of Chicago Press. This book was released on 2019-06-07 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, curators, and analysts. Collecting Experiments traces the development and use of data collections, especially in the experimental life sciences, from the early twentieth century to the present. It shows that the current revolution is best understood as the coming together of two older ways of knowing—collecting and experimenting, the museum and the laboratory. Ultimately, Bruno J. Strasser argues that by serving as knowledge repositories, as well as indispensable tools for producing new knowledge, these databases function as digital museums for the twenty-first century.

Download or read book How Scientists Think written by By George Johnson and published by . This book was released on 2020-01-20 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise book is an intriguing way to foster critical thinking and reinforce the scientific method in your biology course. It expands on the experiments offered in Biology, with 21 chapters devoted to discussions of classic genetics or molecular biology experiments-many on which the study of biology is founded. This short companion is intended to ... provide students with a closer look at some key experiments, as a way of learning how a proper experiment is put together, of seeing how control works, of appreciating the raw originality that sometimes adds flavor and excitement to science-and, above all, of seeing how science is really done. Clean, clear thinking lies at the heart of every good experiment.

Download or read book Great Experiments in Biology written by Mordecai Lionel Gabriel and published by . This book was released on 1964 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Introduction to Experimental Biophysics written by Jay L. Nadeau and published by CRC Press. This book was released on 2016-04-19 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s

Download or read book Experimental Developmental Biology written by Laura R. Keller and published by Academic Press. This book was released on 1999 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is designed for use as a lab manual in college-level courses in developmental biology or animal development. In each exercise, students examine gametes and developing embryos of a single species, and also perform several experiments to probe its developmental process.

Download or read book The Knowledge Machine How Irrationality Created Modern Science written by Michael Strevens and published by Liveright Publishing. This book was released on 2020-10-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The Knowledge Machine is the most stunningly illuminating book of the last several decades regarding the all-important scientific enterprise.” —Rebecca Newberger Goldstein, author of Plato at the Googleplex A paradigm-shifting work, The Knowledge Machine revolutionizes our understanding of the origins and structure of science. • Why is science so powerful? • Why did it take so long—two thousand years after the invention of philosophy and mathematics—for the human race to start using science to learn the secrets of the universe? In a groundbreaking work that blends science, philosophy, and history, leading philosopher of science Michael Strevens answers these challenging questions, showing how science came about only once thinkers stumbled upon the astonishing idea that scientific breakthroughs could be accomplished by breaking the rules of logical argument. Like such classic works as Karl Popper’s The Logic of Scientific Discovery and Thomas Kuhn’s The Structure of Scientific Revolutions, The Knowledge Machine grapples with the meaning and origins of science, using a plethora of vivid historical examples to demonstrate that scientists willfully ignore religion, theoretical beauty, and even philosophy to embrace a constricted code of argument whose very narrowness channels unprecedented energy into empirical observation and experimentation. Strevens calls this scientific code the iron rule of explanation, and reveals the way in which the rule, precisely because it is unreasonably close-minded, overcomes individual prejudices to lead humanity inexorably toward the secrets of nature. “With a mixture of philosophical and historical argument, and written in an engrossing style” (Alan Ryan), The Knowledge Machine provides captivating portraits of some of the greatest luminaries in science’s history, including Isaac Newton, the chief architect of modern science and its foundational theories of motion and gravitation; William Whewell, perhaps the greatest philosopher-scientist of the early nineteenth century; and Murray Gell-Mann, discoverer of the quark. Today, Strevens argues, in the face of threats from a changing climate and global pandemics, the idiosyncratic but highly effective scientific knowledge machine must be protected from politicians, commercial interests, and even scientists themselves who seek to open it up, to make it less narrow and more rational—and thus to undermine its devotedly empirical search for truth. Rich with illuminating and often delightfully quirky illustrations, The Knowledge Machine, written in a winningly accessible style that belies the import of its revisionist and groundbreaking concepts, radically reframes much of what we thought we knew about the origins of the modern world.

Download or read book An Introduction to the Study of Experimental Medicine written by Claude Bernard and published by . This book was released on 1927 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: First English translation of the classical work on the principles of physiological investigation in life sciences.

Download or read book Illustrated Guide to Home Biology Experiments written by Robert Bruce Thompson and published by Maker Media, Inc.. This book was released on 2012-04-17 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experience the magic of biology in your own home lab. This hands-on introduction includes more than 30 educational (and fun) experiments that help you explore this fascinating field on your own. Perfect for middle- and high-school students and DIY enthusiasts, this full-color guide teaches you the basics of biology lab work and shows you how to set up a safe lab at home. The Illustrated Guide to Home Biology Experiments is also written with the needs of homeschoolers firmly in mind, as well as adults who are eager to explore the science of nature as a life-long hobby. To get the most from the experiments, we recommend using this guide in conjunction with a standard biology text, such as the freely downloadable CK-12 Biology (ck-12.org). Master the use of the microscope, including sectioning and staining Build and observe microcosms, soda-bottle worlds of pond life Investigate the chemistry of life from simple acids, bases, and buffers to complex carbohydrates, proteins, lipids, enzymes, and DNA Extract, isolate, and observe DNA Explore photosynthesis, osmosis, nitrogen fixation, and other life processes Investigate the cell cycle (mitosis and cytokinesis) Observe populations and ecosystems, and perform air and water pollution tests Investigate genetics and inheritance Do hands-on microbiology, from simple culturing to micro-evolution of bacteria by forced selection Gain hands-on lab experience to prepare for the AP Biology exam Through their company, The Home Scientist, LLC (thehomescientist.com/biology), the authors also offer inexpensive custom kits that provide specialized equipment and supplies you’ll need to complete the experiments. Add a microscope and some common household items and you’re good to go.

Download or read book Experimental Design and Data Analysis for Biologists written by Gerry P. Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Download or read book Key Experiments in Practical Developmental Biology written by Manuel Marí-Beffa and published by Cambridge University Press. This book was released on 2005-03-24 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 2005, this unique resource presents 27 easy-to-follow laboratory exercises for use in student practical classes in developmental biology. These experiments provide key insights into developmental questions, and many of them are described by the leaders in the field who carried out the original research. This book intends to bridge the gap between experimental work and the laboratory classes taken at the undergraduate and post-graduate levels. All chapters follow the same format, taking the students from materials and methods, through results and discussion, so that they learn the underlying rationale and analysis employed in the research. The book will be an invaluable resource for graduate students and instructors teaching practical developmental biology courses. Chapters include teaching concepts, discussion of the degree of difficulty of each experiment, potential sources of failure, as well as the time required for each experiment to be carried out in a class with students.

Download or read book Experimental Work in Biology written by Donald Gordon Mackean and published by John Murray. This book was released on 1975 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Asking Questions in Biology written by Christopher J. Barnard and published by Prentice Hall. This book was released on 1993 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively book explores how to: Formulate hypotheses and predictions; Design critical observations and experiments to test them; Choose appropriate statistical analyses; Present results and write reports