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Book Experimental and Clinical Neurotoxicology

Download or read book Experimental and Clinical Neurotoxicology written by Peter S. Spencer and published by . This book was released on 1980 with total page 958 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text.The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index.In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.

Book Clinical Neurotoxicology

    Book Details:
  • Author : Michael R. Dobbs
  • Publisher : Elsevier Health Sciences
  • Release : 2009-01-01
  • ISBN : 0323052606
  • Pages : 729 pages

Download or read book Clinical Neurotoxicology written by Michael R. Dobbs and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You'll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors-such as heavy metals and pesticides-and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. And, Expert Consult functionality allows you to access the full text of the book online, from any Internet connection. Provides a complete listing of neurotoxic agents-from manufactured to environmental-so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson's Disease, motor neuron disease, as well as other issues that are still in question. Includes access to www.expertconsult.com, a companion website where you can quickly search the complete contents of the book. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Book Experimental Neurotoxicology Methods

Download or read book Experimental Neurotoxicology Methods written by Jordi Llorens and published by Springer Nature. This book was released on 2021-07-23 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.

Book Neurotoxicology

    Book Details:
  • Author : Louis W. Chang
  • Publisher : Elsevier
  • Release : 1995-04-20
  • ISBN : 0080537472
  • Pages : 875 pages

Download or read book Neurotoxicology written by Louis W. Chang and published by Elsevier. This book was released on 1995-04-20 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. Discusses neurobehavioral testing methods for assessment of neural dysfunctions Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity Presents step-by-step procedures for many methods Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

Book Environmental Neurotoxicology

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 1992-02-01
  • ISBN : 0309045312
  • Pages : 167 pages

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Book Neurotoxicology in Vitro

Download or read book Neurotoxicology in Vitro written by V. Pentreath and published by CRC Press. This book was released on 1999-05-27 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a distinguished panel of experts, students and researchers will find that this comprehensive and accessible volume provides a framework for the study of nerve cells ^in vitro^n for use in experimental neurotoxicology.

Book Neurotoxicology

    Book Details:
  • Author : Mohamed B. Abou-Donia
  • Publisher : CRC Press
  • Release : 1992-07-15
  • ISBN : 9781439805428
  • Pages : 642 pages

Download or read book Neurotoxicology written by Mohamed B. Abou-Donia and published by CRC Press. This book was released on 1992-07-15 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology. It discusses neurotoxic agents, describes the methods for studying neurotoxic actions, covers factors affecting neurotoxicity, and inc

Book Handbook of Developmental Neurotoxicology

Download or read book Handbook of Developmental Neurotoxicology written by William Slikker Jr. and published by Elsevier. This book was released on 1998-08-10 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. Written by internationally recognized experts on developmental neurotoxicology Includes extensive references Well illustrated with diagrams, charts and tables Provides coverage of basic neurobiology as well as neurotoxicology

Book Neuroprotective Agents

Download or read book Neuroprotective Agents written by Bruce Trembly and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Veterinary Toxicology

    Book Details:
  • Author : Ramesh C Gupta
  • Publisher : Elsevier
  • Release : 2011-04-28
  • ISBN : 0080481604
  • Pages : 1233 pages

Download or read book Veterinary Toxicology written by Ramesh C Gupta and published by Elsevier. This book was released on 2011-04-28 with total page 1233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Book Reviews in Environmental Health  1998

Download or read book Reviews in Environmental Health 1998 written by Gary E. R. Hook and published by DIANE Publishing. This book was released on 2000-02 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "man who invented the future," Verne created the prototype for modern science fiction. His prophetic 1870 adventure novel, featuring a bizarre underwater craft commanded by the mysterious Captain Nemo, predated the submarine. The crowning achievement of Verne's literary career, the book influenced H. G. Wells and later generations of writers.

Book Neurotoxicity of Nanomaterials and Nanomedicine

Download or read book Neurotoxicity of Nanomaterials and Nanomedicine written by Xinguo Jiang and published by Academic Press. This book was released on 2016-10-03 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology Includes the most common nanoparticles, their applications, and mechanisms Provides one of the first books to focus on nanomedicine and neurotoxicity

Book Neurotoxicology

    Book Details:
  • Author : Peter G. Bernad
  • Publisher : Lexis Law Publishing (Va)
  • Release : 1998-01-01
  • ISBN : 9780327001324
  • Pages : 407 pages

Download or read book Neurotoxicology written by Peter G. Bernad and published by Lexis Law Publishing (Va). This book was released on 1998-01-01 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Drinking Water and Health

    Book Details:
  • Author : National Research Council
  • Publisher : National Academies Press
  • Release : 1986-02-01
  • ISBN : 0309036879
  • Pages : 476 pages

Download or read book Drinking Water and Health written by National Research Council and published by National Academies Press. This book was released on 1986-02-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.

Book Alterations of Metabolites in the Nervous System

Download or read book Alterations of Metabolites in the Nervous System written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: In neurosciences one may say, '"All roads lead to Rome. " It seems as though wherever one starts, the course of investigation leads to the same major ques tions about nervous system function and dysfunction. In thinking about what to write in this preface, it occurred to me that it might be best to deal with that with which I am most familiar and to trace to some extent my own '"road to Rome. '' As I look over my work of the last 37 years, it becomes clear to me that it can be epitomized as a search for patterns. What usually began as a single minded devotion to in-depth analysis of one or a small number of variables always has led to questions of how the results might relate to the whole living unit, whether it is cell, tissue, or organism. For a number of years after my discovery in the vertebrate central nervous system of -y-aminobutyric acid (GABA) and the enzyme which forms it, L glutamate decarboxylase (GAD), and the identification of GABA as a major inhibitory neurotransmitter by others, I felt that my laboratory, largely bio chemical, was wandering in the wilderness of the complexities of the vertebrate CNS without definitively coming to terms with problems related to GABAergic transmitter functions and the roles of GABA neurons in information processing.

Book Selective Neurotoxicity

    Book Details:
  • Author : Hans Herken
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642851177
  • Pages : 891 pages

Download or read book Selective Neurotoxicity written by Hans Herken and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 891 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the overwhelmingly successful response to the first printing in hardcover, the hottest topics in Selective Neurotoxicity are now available in this special softcover edition". Researchers are provided with well-grounded information on the cellular and subcellular targets of neurotoxins and their mode of action at the level of ion-channels, receptors and neurotransmitters. The use of bacterial toxins as a tool in neuroscientific research is an important aspect in this context. The chapters that interest clinicians as well deal with protective barriers in the peripheral and central nervous system and metabolic disorders that cause neurotoxins to be built up in the human body. The induction of tumors by neuroptropic carcinogens is included.

Book Foundations of Environmental and Occupational Neurotoxicology

Download or read book Foundations of Environmental and Occupational Neurotoxicology written by Jose A. Valciukas and published by Routledge. This book was released on 2019-07-09 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jose A. Valciukas, in Foundations of Environmental and Occupational Neurotoxicology, has written a thorough, lively, and educational study on toxic substances and their effects. Written in a manner that is accessible to both professionals and non-professionals, Dr. Valciukas explains how health and human behavior may be adversely affected by neurotoxins. He introduces his study with a history of environmental and occupational neurotoxicology.