Download or read book Examining the Causal Relationship Between Genes Epigenetics and Human Health written by Wambuguh, Oscar J. and published by IGI Global. This book was released on 2019-03-22 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.
Download or read book Epigenetics and Human Health written by Alexander Haslberger and published by John Wiley & Sons. This book was released on 2009-12-21 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.
Download or read book Epigenetics and Pathology written by Kasirajan Ayyanathan and published by CRC Press. This book was released on 2013-11-25 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters.This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including: host-pathogen interactionscausal relationships between genes and the environmentthe effects
Download or read book Epigenetics and Complex Traits written by Anna K. Naumova and published by Springer Science & Business Media. This book was released on 2013-09-17 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic traits such as observed in common human disease. The relationship between epigenetics and genetics, however, has not been comprehensively summarized yet. The topic is being more and more appreciated lately due to considerable advances in genomic and epigenomic approaches to study the origins of human disease. The editors will focus not only on describing epigenetic characteristics, mechanisms and results, but also on how considerations of epigenetics can alter interpretation and analysis of risks for complex traits. This book will be a resource for those who have been working in human genetics or analysis of human genetic data and are studying the impact of epigenetics on inheritance. An overview will be given of the impacts of inter‐individual variation in epigenetic states from major changes (errors in genomic imprinting) that cause congenital developmental defects to subtle changes and their impact on complex traits. The editors will discuss the relationship between epigenetic changes and genetic changes in human disease. Several chapters will also focus on statistical analysis of epigenetics effects, either in human disease genetic studies, or in population genetics.
Download or read book Specific Gene Expression and Epigenetics written by Kasirajan Ayyanathan and published by Apple Academic Press. This book was released on 2021-03-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters. This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice. The book includes chapters on these topics: - Gene expression in colon cancer tissue - Epigenetics in human acute kidney injury - Embryologically relevant candidate genes in MRKH patients - DNA methylation in common skeletal disorders - Causal relationships in genomics - Predicting severe asthma exacerbations in children - Epigenetic understanding of gene-environment interactions in psychiatric disorders
Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer. This book was released on 2022-04-15 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this book provides a state of the art overview on basic concepts of epigenetic epidemiology and a comprehensive review of the rapidly evolving field of human epigenetics. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. Unlike our genetic inheritance, our epigenome is malleable throughout the lifecourse and is shaped by our environmental experiences. Population-based epidemiologic studies increasingly incorporate epigenetic components. These so called epigenome-wide association studies (EWAS) contribute substantially to our understanding of the relevance of epigenetic marks, such as DNA methylation, histone modification, and non-coding RNAs for disease causation. Written by leading experts in the field, the book opens with a comprehensive introduction of the principles of epigenetic epidemiology and discusses challenges in study design, analysis, and interpretation. It summarizes the latest advances in epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the epigenetic clock, and the role of epigenetics in the developmental origins hypothesis. The final part focuses on epigenetic epidemiology of various health conditions such as imprinting disorders, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, metabolic disorder and vascular disease, as well as neurodevelopmental and psychiatric disorders. Given its scope, Epigenetic Epidemiology is an indispensable resource for researchers working in the field of human epigenetics.
Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
Download or read book Examining a Developmental Approach to Childhood Obesity written by Institute of Medicine and published by National Academies Press. This book was released on 2015-09-08 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific evidence points to the origins of childhood obesity as an outcome of the dynamic interplay of genetic, behavioral, and environmental factors throughout early development, with a compelling body of evidence suggesting that both maternal and paternal nutritional and other exposures affect a child's risk of later obesity. The burgeoning field of epigenetics has led researchers to speculate that many of the observed associations between early developmental exposures and later risk of childhood obesity are mediated, at least in part, through epigenetic mechanisms. To explore the body of evolving science that examines the nexus of biology, environment, and developmental stage on risk of childhood obesity, the Institute of Medicine and the National Research Council convened a workshop in February 2015. The workshop focused on the prenatal period, infancy, and early childhood and addressed evidence from both animal and human studies. Workshop objectives were to (1) identify epigenetic-mediated relationships between exposure to risk factors during sensitive periods of development (gestation through age 3) and subsequent obesity-related outcomes; (2) explore the science around periods of plasticity and potential reversibility of obesity risk in the context of early childhood development; and (3) examine the translation of epigenetic science to guide early childhood obesity prevention and intervention to reduce obesity risk. This report summarizes the information presented and discussed at the workshop.
Download or read book Genes Behavior and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-12-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Download or read book Personal Genome Medicine written by Michael J. Malinowski and published by Cambridge University Press. This book was released on 2023-08-31 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Draws from the past and present of medicine in the U.S. to address the emerging future of personal genome medicine.
Download or read book Epigenetics written by C. David Allis and published by CSHL Press. This book was released on 2007 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer Science & Business Media. This book was released on 2012-01-03 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!
Download or read book Research Anthology on Blockchain Technology in Business Healthcare Education and Government written by Management Association, Information Resources and published by IGI Global. This book was released on 2020-09-30 with total page 1924 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though blockchain technology was originally created as a ledger system for bitcoin to operate on, using it for areas other than cryptocurrency has become increasingly popular as of late. The transparency and security provided by blockchain technology is challenging innovation in a variety of businesses and is being applied in fields that include accounting and finance, supply chain management, and education. With the ability to perform such tasks as tracking fraud and securing the distribution of medical records, this technology is key to the advancement of many industries. The Research Anthology on Blockchain Technology in Business, Healthcare, Education, and Government is a vital reference source that examines the latest scholarly material on trends, techniques, and uses of blockchain technology applications in a variety of industries, and how this technology can further transparency and security. Highlighting a range of topics such as cryptography, smart contracts, and decentralized blockchain, this multi-volume book is ideally designed for academics, researchers, industry leaders, managers, healthcare professionals, IT consultants, engineers, programmers, practitioners, government officials, policymakers, and students.
Download or read book The Oxford Handbook of Developmental Psychology Vol 1 written by Philip David Zelazo and published by Oxford University Press. This book was released on 2013-03-21 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehensive survey of what is now known about psychological development, from birth to biological maturity, and it highlights how cultural, social, cognitive, neural, and molecular processes work together to yield human behavior and changes in human behavior.
Download or read book Nutrition and Epigenetics written by Emily Ho and published by CRC Press. This book was released on 2014-10-16 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors mod
Download or read book Attractors and Higher Dimensions in Population and Molecular Biology Emerging Research and Opportunities written by Zhizhin, Gennadiy Vladimirovich and published by IGI Global. This book was released on 2019-06-28 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: In studying biology, one of the more difficult factors to predict is how parents attributes will affect their children and how those children will affect their own children. Organizing and calculating those vast statistics can become extremely tedious without the proper mathematical and reproductive knowledge. Attractors and Higher Dimensions in Population and Molecular Biology: Emerging Research and Opportunities is a collection of innovative research on the methods and applications of population logistics. While highlighting topics including gene analysis, crossbreeding, and reproduction, this book is ideally designed for academics, researchers, biologists, and mathematicians seeking current research on modeling the reproduction process of a biological population.
Download or read book Biomedical and Clinical Engineering for Healthcare Advancement written by Sriraam, N. and published by IGI Global. This book was released on 2019-07-05 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid development of new technologies has created a lasting impact in the healthcare sector during the past decades. Due to this influence, potential clinical problems have decreased while the quality of healthcare delivery and overall user friendliness has increased and contributed to cost-effective healthcare systems. Biomedical and Clinical Engineering for Healthcare Advancement is an essential reference source that discusses growth in healthcare applications driven by the adoption of new technologies, as well as the expansion of machine learning algorithms for clinical decision making. It focuses on combining vision, motion, data acquisition, and automated control to accelerate the development of affordable and portable medical devices. Featuring research on topics such as artificial intelligence, drug delivery, and retinal imaging, this book is ideally designed for healthcare professionals, biomedical engineers, biomedical professionals, clinicians, hospital directors, physicians, medical students, and clinical researchers.
