Download or read book Evolution and Control in Biological Systems written by Alexander B. Kurzhanski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the IIASA Workshop, November 30-December 4, 1987, Laxenburg, Austria

Download or read book Evolution and Control in Biological Systems written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Evolution and Control in Biological Systems written by INTERNATIONAL INSTITUTE FOR APPLIED SYSTEMS ANALYSIS. Laxenburg (AT) and published by . This book was released on 1989 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Feedback Control in Systems Biology written by Carlo Cosentino and published by CRC Press. This book was released on 2011-10-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.

Download or read book Hormones as Tokens of Selection written by Hugo van den Berg and published by CRC Press. This book was released on 2019-04-30 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones as Tokens of Selection addresses deep questions in biology: How are biological systems controlled? How can one formulate general theories of homeostasis and control and instantiate such theories in mathematical models? How can one use evolutionary arguments to guide our answers to these questions, recognising that the control mechanisms themselves are a product of evolution? Biological systems are exceptionally varied and extremely difficult to understand, because they are complex and experimentation remains limited relative to the challenges at hand. Moreover, biological phenomena occur at a wide range of temporal and spatial scales. Such a deeply convoluted subject calls for a unifying and coherent theoretical foundation — one which recognises and departs from the primary importance of mathematical modelling and key physicochemical principles to theory formation in the life sciences. This Focus monograph proposes and outlines such a foundation, departing from the deceptively simple proposition that hormones are tokens of evolutionary pressures. Features Provides a coherent and unified approach to a multifaceted problem Pays close attention to both the biological and mathematical modelling aspects of the subject matter, exploring the philosophical background where appropriate Written in a concise and innovative style

Download or read book Robustness and Evolvability in Living Systems written by Andreas Wagner and published by Princeton University Press. This book was released on 2013-10-24 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations.

Download or read book Understanding the Dynamics of Biological Systems written by Werner Dubitzky and published by Springer Science & Business Media. This book was released on 2011-01-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as a communication platform to bridge the cultural, conceptual, and technological gap among the key systems biology disciplines of biology, mathematics, and information technology. To support this goal, contributors were asked to adopts an approach that appeals to audiences from different backgrounds.

Download or read book Control Theory and Systems Biology written by Pablo A. Iglesias and published by MIT Press. This book was released on 2010 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.

Download or read book Evolutionary Systems Biology written by Orkun S. Soyer and published by Springer Science & Business Media. This book was released on 2012-07-23 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover “evolutionary design principles” and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.

Download or read book Evolutionary Systems written by G. Vijver and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three well known revolutions of the past centuries - the Copernican, the Darwinian and the Freudian - each in their own way had a deflating and mechanizing effect on the position of humans in nature. They opened up a richness of disillusion: earth acquired a more modest place in the universe, the human body and mind became products of a long material evolutionary history, and human reason, instead of being the central, immaterial, locus of understanding, was admitted into the theater of discourse only as a materialized and frequently out-of-control actor. Is there something objectionable to this picture? Formulated as such, probably not. Why should we resist the idea that we are in certain ways, and to some degree, physically, biologically or psychically determined? Why refuse to acknowledge the fact that we are materially situated in an ever evolving world? Why deny that the ways of inscription (traces of past events and processes) are co-determinative of further "evolutionary pathways"? Why minimize the idea that each intervention, of each natural being, is temporally and materially situated, and has, as such, the inevitable consequence of changing the world? The point is, however, that there are many, more or less radically different, ways to consider the "mechanization" of man and nature. There are, in particular, many ways to get the message of "material and evolutionary determination", as well as many levels at which this determination can be thought of as relevant or irrelevant.

Download or read book Systems Evolutionary Biology written by Bor-Sen Chen and published by Academic Press. This book was released on 2018-02-03 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Evolutionary Biology: Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology discusses the evolutionary game theory and strategies of nonlinear stochastic biological networks under random genetic variations and environmental disturbances and their application to systematic synthetic biology design. The book provides more realistic stochastic biological system models to mimic the real biological systems in evolutionary process and then introduces network evolvability, stochastic evolutionary game theory and strategy based on nonlinear stochastic networks in evolution. Readers will find remarkable, revolutionary information on genetic evolutionary biology that be applied to economics, engineering and bioscience. - Explains network fitness, network evolvability and network robustness of biological networks from the systematic perspective - Discusses the evolutionary noncooperative and cooperative game strategies of biological networks - Offers detailed diagrams to help readers understand biological networks, their systematic behaviors and the simulational results of evolutionary biological networks - Includes examples in every chapter with computational simulation to illustrate the solution procedure of evolutionary theory, strategy and results

Download or read book The Evolution of Biological Organization as a Function of Information written by Ilse Walker and published by . This book was released on 2005 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic concepts. Biological information: the necklace principle of coding. Analogy as a biophysical concept. Symmetry in biological structure and function. Biological complexity: problems of analysis. Growth in the organic hierarchy. Cyclic function and the problem of control. The evolution of the cooperative group and structural individualization. The evolution of systemic mortality as a consequence of central control. Maintenance of information. Mutation and selection. Population growth and selection. Competition. Competition and biodiversity.

Download or read book Evolutionary Change written by Aron Katsenelinboigen and published by Routledge. This book was released on 2019-06-07 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1997 Evolutionary Change addresses the somatic mechanism of change. Although astounding advances in molecular biology have opened up new engineering possibilities to shape our future in terms of "improving" the human species as well as eradicating all kinds of pathological characteristics of biological development, these possibilities pose potentially serious dangers. They arise primarily from the local nature of changes that are introduced and the impact of the environment on the overall development of the biological system. The book explores the biological mechanisms of change in their entirety – as they fit into the general dynamics of biological systems – and demonstrates the pitfalls of tackling change from a narrow perspective, using cancer as an example of certain pathological manifestations of these mechanisms of change.

Download or read book Genomic Control Process written by Isabelle S. Peter and published by Academic Press. This book was released on 2015-01-21 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome

Download or read book Biological Robustness written by Marta Bertolaso and published by Springer. This book was released on 2019-01-04 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews examples and notions of robustness at several levels of biological organization. It tackles many philosophical and conceptual issues and casts an outlook on the future challenges of robustness studies in the context of a practice-oriented philosophy of science. The focus of discussion is on concrete case studies. These highlight the necessity of a level-dependent description of robust biological behaviors.Experts from the neurosciences, biochemistry, ecology, biology, and the history and the philosophy of life sciences provide a multiplex perspective on the topic. Contributions span from protein folding, to cell-level robustness, to organismal and developmental robustness, to sensorimotor systems, up to the robustness of ecological systems.Several chapters detail neurobiological case-studies. The brain, the poster child of plasticity in biology, offers multiple examples of robustness. Neurobiology explores the importance of temporal organization and multiscalarity in making this robustness-with-plasticity possible. The discussion also includes structures well beyond the brain, such as muscles and the complex feedback loops involved in the peculiar robustness of music perception. Overall, the volume grounds general reflections upon concrete case studies, opening to all the life sciences but also to non-biological and bio-inspired fields such as post-modern engineering. It will appeal to researchers, students, as well as non-expert readers.

Download or read book Evolutionary Systems Biology written by Anton Crombach and published by Springer Nature. This book was released on 2021-08-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition captures the advances made in the field of evolutionary systems biology since the publication of the first edition. The first edition focused on laying the foundations of evolutionary systems biology as an interdisciplinary field, where a way of thinking and asking questions is combined with a wide variety of tools, both experimental and theoretical/computational. Since publication of the first edition, evolutionary systems biology is now a well-known term describing this growing field. The new edition provides an overview of the current status and future developments of this interdisciplinary field. Chapters highlight several key achievements from the last decade and outline exciting new developments, including an understanding of the interplay between complexity and predictability in evolutionary systems, new viewpoints and methods to study organisms in evolving populations at the level of the genome, gene regulatory network, and metabolic network, and better analysis and modeling techniques that will open new avenues of scientific inquiry.

Download or read book Evolutionary Biology written by John S. Torday and published by John Wiley & Sons. This book was released on 2012-09-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrative view of the evolution of genetics and the naturalworld Even in this advanced age of genomics, the evolutionary processof unicellular and multicellular organisms is continually indebate. Evolutionary Biology, Cell–Cell Communication, andComplex Disease challenges current wisdom by using physiology topresent an integrative view of the nature, origins, and evolutionof fundamental biological systems. Providing a deeper understanding of the way genes relate to thetraits of living organisms, this book offers useful informationapplying evolutionary biology, functional genomics, and cellcommunication studies to complex disease. Examining the 4.5billion-year evolution process from environment adaptations tocell-cell communication to communication of genetic information forreproduction, Evolutionary Biology hones in on the "why and how" ofevolution by uniquely focusing on the cell as the smallest unit ofbiologic structure and function. Based on empirically derived data rather than associationstudies, Evolutionary Biology covers: A model for forming testable hypotheses in complex diseasestudies The integrating role played by the evolution of metabolism,especially lipid metabolism The evolutionary continuum from development to homeostasis Regeneration and aging mediated by signaling molecules Ambitious and game-changing Evolutionary Biology suggests thatbiology began as a mechanism for reducing energy within the cell,defying the Second Law of Thermodynamics. An ideal text for thoseinterested in forward thinking scientific study, the insightspresented in Evolutionary Biology help practitioners effectivelycomprehend the evolutionary process.