Download or read book Search for the evidence of endocrine disruption in the aquatic environment written by R I L. Eggen and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evidence of Endocrine Disruption in the Aquatic Environment written by Olwenn V. Martin and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Disruptors in the Environment written by Sushil K. Khetan and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruptors in the Environment A concise and engaging overview of endocrine disruption phenomena that brings complex concepts within the reach of non-specialists For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, Endocrine Disruptors in the Environment begins with an overview of the endocrine system and endocrine disruptors, discussing their salient features and presenting a historical perspective of endocrine disruption phenomena. It then goes on to cover hormone- signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs—including their detection, regulation, replacement, and remediation. Endocrine Disruptors in the Environment is the first book to detail the endocrine effects of several known environmental contaminants and their mechanism of endocrine disruption. Additionally, it: Covers both the chemistry and biology of endocrine disruption and compiles almost all the known endocrine disrupting environmental chemicals and their mechanisms of toxicity Addresses policy and regulatory issues relevant to EDCs including scientific uncertainty and precautionary policy Brings forth the use of Green Chemistry principles in avoiding endocrine disruption in the designing and screening for safer chemicals and remediation of the EDCs in aquatic environment Includes a useful glossary of technical terms, a list of acronyms, topical references, and a subject index Endocrine Disruptors in the Environment is an ideal book for environmental chemists and endocrine toxicologists, developmental biologists, endocrinologists, epidemiologists, environmental health scientists and advocates, and regulatory officials tasked with risk assessment in environment and health areas.
Download or read book Environmental Endocrine Disruptors written by A Crain and published by CRC Press. This book was released on 2000-08-17 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses many aspects of endocrine disruption by environmental encountered toxic substances. Initial chapters provide essential background information whilst later chapters address specific aspects of endocrine disrupting contaminants (EDC)
Download or read book Endocrine Disrupting Chemicals written by R M Harrison and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-term environmental effects of chemical exposure have long been of concern and, more recently, chemicals which cause changes to the sexual development of exposed organisms have been identified. It is thought that low-level exposure to a wide range of chemicals may be affecting endocrine function, leading to a reduction in fertility and an increase in reproductive cancers. Endocrine Disrupting Chemicals reviews the scientific evidence and attempts to put the subject into context. Along with an overview of the issue, there is discussion of the specialised aspects in relation to wildlife; environmental oestrogens and male reproduction; and naturally occurring oestrogenic substances. With contributions from representatives of the Medical Research Council's Institute for Environment and Health and the US Environmental Protection Agency, the articles provide a comprehensive and detailed review of current issues. This book will be of interest to a wide readership, including industrial and environmental scientists, managers and policy makers.
Download or read book Endocrine Disruption in Fish written by David E. Kime and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last half-century has shown a dramatic increase in the standard of living of millions of people in Europe, North America and many parts of the Third World. This has, in many ways been brought about by scientific and technical developments which were initiated in the 1940s and 1950s. Promises were then made that nuclear energy would provide electricity so cheap that it would not need metering, pesticides would end malnutrition throughout the world and plastics and other synthetic chemicals would revolutionise our manufacturing industry and our way of life. Whilst some of these promises have been fulfilled, the problems of long-term health risks to humans and wildlife arising from the use, production and disposal of these products were either unknown or deliberately understated. Nuclear power is rendered economically unviable when the real cost of decommissioning and storage of waste for several millenia is included, and the effects on health of both humans and wildlife of early pest eradication programmes with organochlorine pesticides were well documented in Rachel Carson's "Silent Spring". Evidence of the effects of aerosols and refrigerants on depletion of the ozone layer has led to restriction on the use of CFCs, and there is now increasing evidence of climate change resulting from our profligate use of fossil fuels.
Download or read book Endocrine disrupting Chemicals in Drinking Water written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Energy and Environment and published by . This book was released on 2012 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigations of Endocrine Disruption in Aquatic Systems Associated with the National Water Quality Assessment NAWQA Program written by and published by . This book was released on 1998 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sicker Fatter Poorer written by Leonardo Trasande and published by Houghton Mifflin. This book was released on 2019 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading voice in public health policy and top environmental medicine scientist reveals the alarming truth about how hormone-disrupting chemicals are affecting our daily lives--and what we can do to protect ourselves and fight back. Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we've turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Dr. Trasande exposes the chemicals that disrupt our hormonal systems and damage our health in irreparable ways. He shows us where these chemicals hide--in our homes, our schools, at work, in our food, and countless other places we can't control--as well as the workings of policy that protects the continued use of these chemicals in our lives. Drawing on extensive research and expertise, he outlines dramatic studies and emerging evidence about the rapid increases in neurodevelopmental, metabolic, reproductive, and immunological diseases directly related to the hundreds of thousands of chemicals that we are exposed to every day. Unfortunately, nowhere is safe. But, thanks to Dr. Trasande's work on the topic, and his commitment to effecting change, this book can help. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he shows us what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
Download or read book Endocrine Disrupters in Wastewater and Sludge Treatment Processes written by Jason W. Birkett and published by CRC Press. This book was released on 2002-11-25 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disrupting Chemicals (EDCs) have been shown to produce changes in the endocrine system of organisms, leading to increases in cancers and abnormalities in reproductive structure and function. This book presents research on the endocrine-disrupting effects of sewage and industrial effluents, covering the sources, fate, and transport of EDCs
Download or read book Tracing Endocrine Disruptors written by Corine Jantien Houtman and published by . This book was released on 2007 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Disruptors and The Developing Brain written by Andrea C. Gore and published by Biota Publishing. This book was released on 2012-05-01 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of endocrine disruption has been the focus of increasing attention from scientists and the general public in the past 30 years, amidst concerns that exposure to environmental chemicals with the potential to alter endocrine system function, known as endocrine disrupting chemicals (EDCs), may be contributing to an overall decline in wildlife populations and the reproductive health of humans. These concerns are based on observations of adverse effects of EDCs on marine and land animals, an increased incidence of reproductive and endocrine disease in humans, epidemiological evidence for links between body burden and disease, and endocrine disruption in laboratory animals following exposure to EDCs. Owing to its role in regulation of endocrine function as well as its responsiveness to hormones, the developing brain is an especially vulnerable target for many classes of EDCs. This book will address the evidence for EDC action on the developing brain, organized into 7 chapters. Topics covered include background about EDCs, evidence for exposures, concerns about EDC effects in the developing organism, and particularly on the developing nervous system, how EDCs perturb the brain's neuroendocrine systems, transgenerational epigenetic effects of EDCs, EDC effects on non-reproductive behaviors, and future perspectives. This is the first book completely dedicated to understanding links between EDCs and the developing brain, an area of emerging importance for human health.
Download or read book Assessment of Streams and Aquatic Organisms in the Vicinity of Birmingham Alabama for the Presence and Biological Activity of Endocrine disrupting Chemicals written by Bryan S. Arwood and published by . This book was released on 2015 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Freshwater ecosystems play a central role in the environment. Through various processes such as nutrient recycling, groundwater recharging, and the attenuation of many pollutants these biological systems help to maintain environmental health. Unfortunately, many recent studies have identified emerging threats to these special environments and the life they sustain. One source of mounting concern is a group of compounds that interact with the endocrine systems of humans and wildlife. Known as endocrine disrupting chemicals (EDCs), these natural and synthetic chemicals may mimic or interfere with the action of natural hormones--thus disrupting the endocrine system. Multiple studies have reported negative effects associated with EDCs on both the health of humans and wildlife; however more information is needed on the reproductive effects that EDCs may pose to wildlife, in particular fish inhabiting these freshwater ecosystems. Fish serve as a useful indicator of the health of an aquatic ecosystem. To this end, the scope of the current investigation provides an integrated approach in assessing the streams and aquatic organisms in the vicinity of Birmingham, Alabama for the presence and biological activity of EDCs. It follows a preliminary study conducted at several sites along the Cahaba River in which a yeast estrogen screen (YES) detected sufficient estrogenicity in water samples to imply the possible feminization of fish. Repeated samples were collected between 2012 and 2013 providing an assessment to the extent of seasonal and annual variation in estrogenic activity. Using the same YES assay as employed previously, it was determined that water samples collected at several wastewater treatment plant (WWTPs) outfalls contained estrogenic components in concentrations sufficient to cause endocrine disruption in aquatic organisms. Water samples were further analyzed using tandem liquid chromatograph/mass spectrometry and the predominant estrogenic components identified. At WWTPs where habitats were suitable, specimens of largescale stoneroller ( Campostoma oligolepis ) were collected and biomarkers of endocrine disruption evaluated. Such biomarkers included the presence of intersex, reduced gonad size in males and/or females, and reduced secondary sex characteristics within males. In each study described within this dissertation, chemical and biological evidence suggests that environmental estrogens were present at low-level concentrations during the sampling window represented here. Environmental estrogens detected in water samples from the WWTPs investigated illustrated non-significant seasonal influence of environmental concentration. Neither LC/MS nor the YES assay detected significant estrogen loading into receiving bodies of water via wastewater effluent. Additionally, biomarkers for endocrine disruption evaluated within C. oligolepis failed to detect significant differences in either histology or morphology between WWTP present and WWTP absent sites. We conclude that the WWTPs assessed in this study are not currently contributing environmental estrogens to the receiving waters in concentrations sufficient to produce discernible effects upon the fish populations within Jefferson County, Alabama; this is primarily due to their presence at low-level concentrations and intermittent persistence within receiving bodies of water.
Download or read book Transcriptomic Analysis of Endocrine Disruption in Californian Sentinel Fish Species written by and published by . This book was released on 2012 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine disruptors are the substances which disrupt the normal functioning of the endocrine system by interfering with the variety of hormone-regulated physiological pathways and causing adverse health effects on the organism's physiology. They include plasticizers, pesticides, detergents and pharmaceuticals. These substances find their way into rivers and the ocean through sewage discharge and sediments at the bottom. Humans are also exposed to these toxic chemicals owing to water and fish consumption. The pelagic fish, which are bottom feeders, are at the highest risk of exposure to these harmful chemicals which settle in ocean sediments. As evidence of the threat of endocrine disrupting chemicals (EDCs) is mounting, there is a need to revise our research and improve our diagnostic efforts. With the advent of high-throughput sequencing technologies, we can now look at the complete transcriptional characterization of an organism. Sentinel fish, indicators of the environmental hazards, provide assessment for the endocrine disrupting chemicals present in the marine environment. For this thesis project, the RNA-Sequencing data of Sardine, Mackerel and Turbot were analyzed to obtain detailed snapshots of the transcriptome in both control (unpolluted) and impacted (polluted) fish. The RNA-Seq analysis of the altered expression patterns of the genes involved in important metabolic and physiological processes will provide a powerful tool for obtaining complete picture of the endocrine disruption in aquatic organisms.
Download or read book Proceedings of the 1997 Great Lakes Endocrine Disrupters Symposium written by and published by . This book was released on 1997 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Regulation Epigenetics and Hormone Signaling written by Subhrangsu S. Mandal and published by John Wiley & Sons. This book was released on 2017-10-23 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.
Download or read book Road to regulation of endocrine disruptors and combination effects written by Karina Petersen and published by Nordic Council of Ministers. This book was released on 2014-05-06 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussions regarding regulation of endocrine disruptors (EDs) and combination effects are ongoing in Europe. Among the central topics of discussion are establishment of criteria for identification of EDs, whether there is a threshold for endocrine disrupting effects and how EDs should be handled within relevant EU regulations. In addition, a roadmap for further EU work regarding combination effects has been presented, but more detailed discussions are needed regarding scientific issues and regulatory intervention. Possible Member State initiatives to provide input to these EU processes were discussed in a Nordic workshop held in Oslo in November 2013. This report describes the workshop presentations, initiatives and thoughts from each of the Nordic countries, the plenary discussions, and the main workshop outcomes.
