Download or read book Evaluation of the Subcutaneous Route for Closed loop Control of Glucose written by Zlatko Trajanoski and published by . This book was released on 1995 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Discovery and Evaluation Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Download or read book 1995 IEEE Engineering in Medicine and Biology written by IEEE Engineering in Medicine and Biology Society. Annual Conference and published by Institute of Electrical & Electronics Engineers(IEEE). This book was released on 1997 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Managing Diabetes and Hyperglycemia in the Hospital Setting written by Boris Draznin and published by American Diabetes Association. This book was released on 2016-05-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.
Download or read book Type 1 Diabetes An Issue of Endocrinology and Metabolism Clinics of North America E Book written by Desmond A. Schatz and published by Elsevier Health Sciences. This book was released on 2010-09-21 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Endocrinology and Metabolism Clinics of North America provides the endocrinologist with essential updates on treatment of type 1 diabetes, with an eye toward future trends and developments. The Guest Editors brought together a remarkable group of notable authors, such as Paul Robertson, President of the National Diabetes Association. Topics covered include epidemiology; economics; contemporary management; inpatient management; update on insulin pumps and continuous glucose monitoring systems; update on studies aimed at interdicting and preventing type 1 diabetes; advances in the prediction, natural history, and mechanisms leading to type 1 diabetes; complications; hypoglycemia in type 1 diabetes; new lessons from animal models; the role of the gut in the genesis of type 1 diabetes and other autoimmune diseases; and an update on transplantation for reversing type 1 diabetes.
Download or read book Encyclopedia of Systems and Control written by John Baillieul and published by Springer. This book was released on 2015-07-29 with total page 1554 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Systems and Control collects a broad range of short expository articles that describe the current state of the art in the central topics of control and systems engineering as well as in many of the related fields in which control is an enabling technology. The editors have assembled the most comprehensive reference possible, and this has been greatly facilitated by the publisher’s commitment continuously to publish updates to the articles as they become available in the future. Although control engineering is now a mature discipline, it remains an area in which there is a great deal of research activity, and as new developments in both theory and applications become available, they will be included in the online version of the encyclopedia. A carefully chosen team of leading authorities in the field has written the well over 250 articles that comprise the work. The topics range from basic principles of feedback in servomechanisms to advanced topics such as the control of Boolean networks and evolutionary game theory. Because the content has been selected to reflect both foundational importance as well as subjects that are of current interest to the research and practitioner communities, a broad readership that includes students, application engineers, and research scientists will find material that is of interest.
Download or read book Introduction to Modeling in Physiology and Medicine written by Claudio Cobelli and published by Elsevier. This book was released on 2008-02-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises
Download or read book In Vivo Glucose Sensing written by David D. Cunningham and published by John Wiley & Sons. This book was released on 2009-11-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.
Download or read book Health Technology Assessment Reports written by and published by . This book was released on 1983 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electrical Electronics Abstracts written by and published by . This book was released on 1997 with total page 2240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prediction Methods for Blood Glucose Concentration written by Harald Kirchsteiger and published by Springer. This book was released on 2015-11-24 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of counter-measures. The glucose prediction algorithms described are also a key and critical ingredient of automated insulin delivery systems, the so-called “artificial pancreas”. The authors address the topic of blood-glucose prediction from medical, scientific and technological points of view. Simulation studies are utilized for complementary analysis but the primary focus of this book is on real applications, using clinical data from diabetic subjects. The text details the current state of the art by surveying prediction algorithms, and then moves beyond it with the most recent advances in data-based modeling of glucose metabolism. The topic of performance evaluation is discussed and the relationship of clinical and technological needs and goals examined with regard to their implications for medical devices employing prediction algorithms. Practical and theoretical questions associated with such devices and their solutions are highlighted. This book shows researchers interested in biomedical device technology and control researchers working with predictive algorithms how incorporation of predictive algorithms into the next generation of portable glucose measurement can make treatment of diabetes safer and more efficient.
Download or read book 4th Kuala Lumpur International Conference on Biomedical Engineering 2008 written by Noor Azuan Abu Osman and published by Springer Science & Business Media. This book was released on 2008-07-30 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is with great pleasure that we present to you a collection of over 200 high quality technical papers from more than 10 countries that were presented at the Biomed 2008. The papers cover almost every aspect of Biomedical Engineering, from artificial intelligence to biomechanics, from medical informatics to tissue engineering. They also come from almost all parts of the globe, from America to Europe, from the Middle East to the Asia-Pacific. This set of papers presents to you the current research work being carried out in various disciplines of Biomedical En- neering, including new and innovative researches in emerging areas. As the organizers of Biomed 2008, we are very proud to be able to come-up with this publication. We owe the success to many individuals who worked very hard to achieve this: members of the Technical Committee, the Editors, and the Inter- tional Advisory Committee. We would like to take this opportunity to record our thanks and appreciation to each and every one of them. We are pretty sure that you will find many of the papers illuminating and useful for your own research and study. We hope that you will enjoy yourselves going through them as much as we had enjoyed compiling them into the proceedings. Assoc. Prof. Dr. Noor Azuan Abu Osman Chairperson, Organising Committee, Biomed 2008
Download or read book Patient Specific Controller for an Implantable Artificial Pancreas written by Yvonne Ho and published by Springer. This book was released on 2018-09-14 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country’s prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant.
Download or read book Technological Advances in the Treatment of Type 1 Diabetes written by D. Bruttomesso and published by Karger Medical and Scientific Publishers. This book was released on 2014-11-17 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.
Download or read book Chance Discoveries in Real World Decision Making written by Yukio Ohsawa and published by Springer Science & Business Media. This book was released on 2006-09-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: For this book, the editors invited and called for contributions from indispensable research areas relevant to "chance discovery," which has been defined as the discovery of events significant for making a decision, and studied since 2000. From respective research areas as artificial intelligence, mathematics, cognitive science, medical science, risk management, methodologies for design and communication, the invited and selected authors in this book present their particular approaches to chance discovery. The chapters here show contributions to identifying rare or hidden events and explaining their significance, predicting future trends, communications for scenario development in marketing and design, identification effects and side-effects of medicines, etc. The methods presented in this book are based on the interaction of human, machine, and human's living environment, rather than based purely automated predictions of the future. This is a promising direction of computer-supported decision of human in a radically changing environment.
Download or read book Quantitative Systems Pharmacology written by Davide Manca and published by Elsevier. This book was released on 2018-07-18 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource. Outlines a model-based approach (based on Process Systems Engineering-OSE and Computer Aided Process Engineering-CAPE) in quantitative pharmacology Explains how therapeutics work in the human body and how anatomy and physiology influences drug efficacy Discusses how drugs are driven to specific targets using nanoparticles Offers insight into how in vitro and in vivo experiments help understand the drug mechanism of action and optimize their performance Includes case studies showing the positive outcome of these methods in personalized therapies, therapeutic drug monitoring, clinical trials analysis and drug formulation
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
